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Phase behavior of mixed Langmuir monolayers from amphiphilic block copolymers and an antimicrobial peptide

Haefele, Thomas and Kita-Tokarczyk, Katarzyna and Meier, Wolfgang. (2006) Phase behavior of mixed Langmuir monolayers from amphiphilic block copolymers and an antimicrobial peptide. Langmuir, 22 (3). pp. 1164-1172.

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Official URL: http://edoc.unibas.ch/dok/A5265243

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Abstract

The behavior of binary monolayers from PMOXA-PDMS-PMOXA triblock copolymers and alamethicin, an antimicrobial peptide, was investigated in the context of formation of novel biocomposite nanostructured materials. The properties of mixed monolayers were studied by surface pressure-area isotherms and Brewster angle imaging. As reported previously, functionality of alamethicin relies on its aggregation properties in lipid mono- and bilayers. This is also the case in polymer matrixes, however, here the mixing properties differ from lipid-peptide systems due to the polymers' structural specificity. The peptide influence on the polymer films is provided in detail for the first time, and supported by the compressibility data to assess the elastic properties of such composite membranes. [on SciFinder (R)]
Faculties and Departments:05 Faculty of Science > Departement Chemie > Chemie > Makromolekulare Chemie (Meier)
UniBasel Contributors:Kita-Tokarczyk, Katarzyna and Meier, Wolfgang P.
Item Type:Article, refereed
Article Subtype:Research Article
Bibsysno:Link to catalogue
Publisher:American Chemical Society
ISSN:0743-7463
e-ISSN:1520-5827
Note:Publication type according to Uni Basel Research Database: Journal article
Language:English
Identification Number:
Last Modified:11 Mar 2020 15:41
Deposited On:22 Mar 2012 14:06

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