Why do people with anxiety disorders become depressed? : a prospective-longitudinal community study

Wittchen, H.-U. and Kessler, R. C. and Pfister, H. and Höfler, M. and Lieb, R.. (2000) Why do people with anxiety disorders become depressed? : a prospective-longitudinal community study. Acta psychiatrica Scandinavica. Supplementum, 406. pp. 14-23.

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Official URL: http://edoc.unibas.ch/dok/A5253557

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Objective: To examine the temporal relationships of anxiety and depressive disorders, their risk factors and to explore why people with anxiety develop depression. Method: Data from an original 4-5-year prospective-longitudinal community study (N = 3021) of adolescents and young adults with DSM-IV anxiety and depressive disorders identified with the Composite International Diagnostic Interview are used to examine risk factors, as well as course and outcome. Results: (i) Anxiety disorders, except for panic disorder, are almost always primary conditions. (ii) Over the follow-up period, rates of comorbid anxiety-depression increased substantially and resulted in increased impairment and disabilities. (iii) Predictors for first onset of 'pure' depressive and 'pure' anxiety disorders revealed recognizable differences. (iv) Baseline clinical characteristics of anxiety disorders were significantly associated with an increased risk to develop major depression over the follow-up period. Conclusion: Findings suggest that most anxiety disorders are primary disorders that substantially increase the risk for secondary depression.
Faculties and Departments:07 Faculty of Psychology > Departement Psychologie > Forschungsbereich Klinische Psychologie und Neurowissenschaften > Klinische Psychologie und Epidemiologie (Lieb)
UniBasel Contributors:Lieb, Roselind
Item Type:Article, refereed
Article Subtype:Research Article
Note:Also published in: Anxiety and depression. - Copenhagen : Munksgaard, 2000. - S. 14-23 -- Publication type according to Uni Basel Research Database: Journal article
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Last Modified:22 Mar 2012 14:27
Deposited On:22 Mar 2012 14:00

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