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Items where Division is "05 Faculty of Science > Departement Chemie > Chemie > Molecular Bionics (Seebeck)"

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Number of items at this level: 56.

2022

Beliaeva, Mariia A. and Atac, Reyhan and Seebeck, Florian P.. (2022) Bacterial Degradation of Nτ-Methylhistidine. ACS Chemical Biology, 17 (7). pp. 1989-1995.

Beliaeva, Mariia A. and Seebeck, Florian P.. (2022) Discovery and Characterization of the Metallopterin-Dependent Ergothioneine Synthase from Caldithrix abyssi. JACS Au, 2 (9). pp. 2098-2107.

Igareta, Nico Valerio. Expanding the secondary coordination sphere of streptavidin-based artificial metalloenzymes and their characterization. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Leisinger, Florian. How structure guides function: ergothioneine anabolism and catabolism formylglycine generating enzyme methyl transferases. 2022, Doctoral Thesis, University of Basel, Faculty of Science.

Wen, Xiaojin and Leisinger, Florian and Leopold, Viviane and Seebeck, Florian P.. (2022) Synthetic Reagents for Enzyme-Catalyzed Methylation. Angewandte Chemie International Edition, 61 (41). e202208746.

2021

Beliaeva, Mariia A. and Burn, Reto and Lim, David and Seebeck , Florian P.. (2021) In Vitro Production of Ergothioneine Isotopologues. Angewandte Chemie International Edition, 60 (10). pp. 5209-5212.

Beliaeva, Mariia A. and Leisinger, Florian and Seebeck, Florian P.. (2021) In Vitro Reconstitution of a Five-Step Pathway for Bacterial Ergothioneine Catabolism. ACS Chemical Biology, 16 (2). pp. 397-403.

Burn, Reto. Enzymatic strategies for carbon-sulfur bond formation in ergothioneine biosynthesis. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Duncombe, Todd and Ponti, Aron and Seebeck, Florian Peter and Dittrich, Petra. (2021) UV-Vis Spectra-Activated Droplet Sorting for Label-Free Chemical Identification and Collection of Drople. Analytical Chemistry, 93 (38). pp. 13008-13013.

Leisinger, Florian and Miarzlou , Dzmitry A. and Seebeck, Florian P.. (2021) Non-Coordinative Binding of O2 at the Active Center of a Copper-Dependent Enzyme. Angewandte Chemie International Edition, 60 (11). pp. 6154-6159.

Miarzlou, Dzmitry. Insights into the mechanism and structure of formylglycine generating enzyme. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

Peng, Jiaming and Liao, Cangsong and Bauer, Carste and Seebeck, Florian Peter. (2021) Fluorinated S-Adenosylmethionine as a Reagent for Enzyme-Catalyzed Fluoromethylation. Angewandte Chemie International Edition, 60 (52). pp. 27178-27183.

Schneider, Peter and Henßen, Birgit and Paschold, Beatrix and Chapple, Benjamin P. and Schatton, Marcel and Seebeck, Florian Peter and Classen , Thomas and Pietruszka, Jörg. (2021) Biocatalytic C3-Indole Methylation-A Useful Tool for the Natural-Product-Inspired Stereoselective Synthesis of Pyrroloindoles. Angewandte Chemie International Edition, 60 (43). pp. 23412-23418.

Vallapurackal, Jaicy. Development of a Microfluidics-Based Screening Assay for the High-Throughput Directed Evolution of Artificial Metalloenzymes. 2021, Doctoral Thesis, University of Basel, Faculty of Science.

2020

Flückger, Sebastian and Igareta, Nico V. and Seebeck, Florian P.. (2020) Convergent Evolution of Fungal Cysteine Dioxygenases. ChemBioChem, 21 (21). pp. 3082-3086.

Goncharenko, Kristina V. and Flückiger, Sebastian and Liao, Cangsong and Lim, David and Stampfli, Anja R. and Seebeck, Florian P.. (2020) Selenocysteine as a Substrate, an Inhibitor and a Mechanistic Probe for Bacterial and Fungal Iron-Dependent Sulfoxide Synthases. Chemistry - A European Journal, 26 (6). pp. 1328-1334.

Liao, Cangsong and Seebeck, Florian P.. (2020) Asymmetric β-Methylation of l- and d-α-Amino Acids by a Self-Contained Enzyme Cascade. Angewandte Chemie International Edition, 59 (18). pp. 7184-7187.

Lim, David and Wen, Xiaojin and Seebeck, Florian P.. (2020) Selenoimidazolium Salts as Supramolecular Reagents for Protein Alkylation. Chembiochem : a European journal of chemical biology, 21 (24). pp. 3515-3520.

Maurer, Alice. The Mechanism of Enzyme-catalyzed Ergothioneine Degradation. 2020, Doctoral Thesis, University of Basel, Faculty of Science.

Maurer, Alice and Seebeck, Florian P.. (2020) Reexamination of the Ergothioneine Biosynthetic Methyltransferase EgtD from Mycobacterium tuberculosis as a Protein Kinase Substrate. ChemBioChem, 21 (20). pp. 2908-2911.

Milito, Alfonsina and Castellano, Immacolata and Burn, Reto and Seebeck, Florian P. and Brunet, Christophe and Palumbo, Anna. (2020) First evidence of ovothiol biosynthesis in marine diatoms. Free radical biology and medicine, 152. pp. 680-688.

Stampfli, Anja R. and Blankenfeldt, Wulf and Seebeck, Florian P.. (2020) Structural basis of ergothioneine biosynthesis. Current Opinion in Structural Biology, 65. pp. 1-8.

Stampfli, Anja R. and Seebeck, Florian P.. (2020) The catalytic mechanism of sulfoxide synthases. Current Opinion in Chemical Biology, 59. pp. 111-118.

2019

Di Girolamo, Salvatore. First characterization of a class F sortase and establishment of a microreactor-based assay for its directed evolution. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Engi, Pascal. Chemical probes for mechanistic enzymology. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Leisinger, Florian and Burn, Reto and Meury, Marcel and Lukat, Peer and Seebeck, Florian P.. (2019) Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis. Journal of the American Chemical Society, 141 (17). pp. 6906-6914.

Liao, Cangsong and Seebeck, Florian P.. (2019) S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reactions. Nature Catalysis , 2 (8). pp. 696-701.

Liao, Cangsong and Seebeck, Florian Peter. (2019) In vitro reconstitution of bacterial DMSP biosynthesis. Angew. Chemie Int. Ed, 35. pp. 3553-3556.

Lim, David and Gründemann, Dirk and Seebeck, Florian P.. (2019) Total Synthesis and Functional Characterization of Selenoneine. Angewandte Chemie International Edition, 58 (42). pp. 15026-15030.

Maurer, Alice and Leisinger, Florian and Lim, David and Seebeck, Florian P.. (2019) Structure and Mechanism of Ergothionase from Treponema denticola. Chemistry - A European Journal, 25 (44). pp. 10298-10303.

Miarzlou, Dzmitry A. and Leisinger, Florian and Joss, Daniel and Häussinger, Daniel and Seebeck, Florian P.. (2019) Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen. Chemical Science, 10 (29). pp. 7049-7058.

Stampfli, Anja R.. The Diversity of the Iron-dependent Sulfoxide Synthases in Ergothioneine Biosynthesis. 2019, Doctoral Thesis, University of Basel, Faculty of Science.

Stampfli, Anja R. and Goncharenko, Kristina V. and Meury, Marcel and Dubey, Badri N. and Schirmer, Tilman and Seebeck, Florian P.. (2019) An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum. Journal of American Chemical Society, 141 (13). pp. 5275-5285 .

2018

Castellano, Immacolata and Seebeck, Florian P.. (2018) On ovothiol biosynthesis and biological roles: from life in the ocean to therapeutic potential. Natural Product Reports, 35 (12). pp. 1241-1250.

Flückiger, Sebastian. Mechanistic studies of sulfur-carbon bond formation by metal-dependent enzymes. 2018, Doctoral Thesis, University of Basel, Faculty of Science.

Gamage, Akshamal M. and Liao, Cangsong and Cheah, Irwin K. and Chen, Yahua and Lim, Daniel R. X. and Ku, Joanne W. K. and Chee, Rhonda Sin Ling and Gengenbacher, Martin and Seebeck, Florian P. and Halliwell, Barry and Gan, Yunn-Hwen. (2018) The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection. FASEB Journal, 32 (12). pp. 6395-6409.

Misson, Laëtitia and Burn, Reto and Vit, Allegra and Hildesheim, Julia and Beliaeva, Mariia A. and Blankenfeldt, Wulf and Seebeck, Florian P.. (2018) Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD. ACS Chemical Biology, 13 (5). pp. 1333-1342.

2017

Burn, Reto and Misson, Laëtitia and Meury, Marcel and Seebeck, Florian P.. (2017) Anaerobic Origin of Ergothioneine. Angewandte Chemie International Edition, 56 (41). pp. 12508-12511.

Faponle, Abayomi S. and Seebeck, Florian P. and de Visser, Sam P.. (2017) Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme. Journal of the American Chemical Society, 139 (27). pp. 9259-9270.

Goncharenko, Kristina. The catalytic mechanism of the iron-dependent sulfoxide synthase EgtB. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Knop, Matthias. Identification and characterization of a novel copper dependent enzyme. 2017, Doctoral Thesis, University of Basel, Faculty of Science.

Knop, Matthias and Dang, Thanh Quy and Jeschke, Gunnar and Seebeck, Florian P.. (2017) Copper is a Cofactor of the Formylglycine-Generating Enzyme. ChemBioChem, 18 (2). pp. 161-165.

Knop, Matthias and Lemnaru, Roxana and Seebeck, Florian P.. (2017) Mutation of Conserved Residues Increases in Vitro Activity of the Formylglycine-Generating Enzyme. ChemBioChem, 18 (17). pp. 1755-1761.

Liao, Cangsong and Seebeck, Florian P.. (2017) Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria. ChemBioChem, 18 (21). pp. 2115-2118.

Meury, Marcel and Knop, Matthias and Seebeck, Florian P.. (2017) Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme. Angewandte Chemie International Edition, 56 (28). pp. 8115-8119.

2016

Goncharenko, Kristina and Seebeck, Florian P.. (2016) Conversion of a non-heme iron-dependent sulfoxide synthase into a thiol dioxygenase by a single point mutation. Chemical Communications , 52 (9). pp. 1945-1948.

Lemnaru, Roxana. A chemoenzymatic strategy for protein-nanocellulose conjugates. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

Misson, Laëtitia. Insights into the mechanism and regulation of EgtD, a novel histidine methyltransferase from ergothioneine biosynthesis. 2016, Doctoral Thesis, University of Basel, Faculty of Science.

2015

Goncharenko, Kristina V. and Vit, Allegra and Blankenfeldt, Wulf and Seebeck, Florian P.. (2015) Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway. Angewandte Chemie International Edition, 54 (9). pp. 2821-2824.

Knop, Matthias and Engi, Pascal and Lemnaru, Roxana and Seebeck, Florian P.. (2015) In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I). ChemBioChem, 16 (15). pp. 2147-2150.

Vit, Allegra and Mashabela, Gabriel and Blankenfeldt, Wulf and Seebeck, Florian P.. (2015) Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC. ChemBioChem, 16 (10). pp. 1490-1496.

Vit, Allegra and Misson, L. and Blankenfeldt, W. and Seebeck, Florian P.. (2015) Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis. ChemBioChem, 16 (1). pp. 119-125.

2014

Vit, Allegra and Misson, Laetitia and Blankenfeldt, W. and Seebeck, Florian. (2014) Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 70 (5). pp. 676-680.

2013

Mashabela, Gabriel and Florian, Seebeck. (2013) Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis. Chemical Communications, 49 (70). pp. 7714-7716.

Seebeck, Florian. (2013) Thiohistidine biosynthesis. Chimia, 67 (5). pp. 333-336.

2012

Hofmann, Frank and Szostak, Jack W. and Seebeck, Florian P.. (2012) In vitro selection of functional lantipeptides. Journal of the American Chemical Society, 134 (19). pp. 8038-8041.

This list was generated on Thu Mar 28 03:59:04 2024 CET.