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Items where Division is "05 Faculty of Science > Departement Biozentrum > Neurobiology > Pharmacology/Neurobiology (Rüegg)"

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Number of items at this level: 166.

May 2016

Reinhard, Judith R. and Kriz, Alexander and Galic, Milos and Angliker, Nico and Rajalu, Mathieu and Vogt, Kaspar E. and Rüegg, Markus A.. (2016) The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory. Nature communications, 7. p. 11613.

21 March 2016

Guridi, Maitea and Kupr, Barbara and Romanino, Klaas and Lin, Shuo and Falcetta, Denis and Tintignac, Lionel and Rüegg, Markus A.. (2016) Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism. Skeletal muscle, 6. p. 13.

9 February 2016

Zhang, Lianjun and Tschumi, Benjamin O. and Lopez-Mejia, Isabel C. and Oberle, Susanne G. and Meyer, Marten and Samson, Guerric and Rüegg, Markus A. and Hall, Michael N. and Fajas, Lluis and Zehn, Dietmar and Mach, Jean-Pierre and Donda, Alena and Romero, Pedro. (2016) Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. Cell reports, 14 (5). pp. 1206-1217.

February 2016

Schell, Christoph and Kretz, Oliver and Liang, Wei and Kiefer, Betina and Schneider, Simon and Sellung, Dominik and Bork, Tillmann and Leiber, Christian and Rüegg, Markus A. and Mallidis, Con and Schlatt, Stefan and Mayerhofer, Artur and Huber, Tobias B. and Grahammer, Florian. (2016) The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. American journal of pathology, 186 (2). pp. 324-336.

6 January 2016

Ruegsegger, Céline and Stucki, David M. and Steiner, Silvio and Angliker, Nico and Radecke, Julika and Keller, Eva and Zuber, Benoît and Rüegg, Markus A. and Saxena, Smita. (2016) Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. Neuron, 89 (1). pp. 129-146.

2016

Shende, Pankaj and Xu, Lifen and Morandi, Christian and Pentassuglia, Laura and Heim, Philippe and Lebboukh, Sonia and Berthonneche, Corinne and Pedrazzini, Thierry and Kaufmann, Beat A. and Hall, Michael N. and Rüegg, Markus A. and Brink, Marijke. (2016) Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovascular research, 109 (1). pp. 103-114.

4 December 2015

Aimi, Fabio and Georgiopoulou, Stavroula and Kalus, Ina and Lehner, Fabienne and Hegglin, Alica and Limani, Përparim and Gomes de Lima, Vinicius and Rüegg, Markus A. and Hall, Michael N. and Lindenblatt, Nicole and Haas, Elvira and Battegay, Edouard J. and Humar, Rok. (2015) Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Scientific reports, 5. p. 17705.

10 November 2015

Guridi, Maitea and Tintignac, Lionel A. and Lin, Shuo and Kupr, Barbara and Castets, Perrine and Rüegg, Markus A.. (2015) Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21. Science signaling, 8 (402). ra113.

October 2015

Angliker, Nico and Burri, Michael and Zaichuk, Mariana and Fritschy, Jean-Marc and Rüegg, Markus A.. (2015) mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. The European journal of neuroscience, 42 (8). pp. 2595-2612.

2015

Angliker, Nico. Distinct and common functions of mTORC1 and mTORC2 in Purkinje cells. 2015, PhD Thesis, University of Basel, Faculty of Science.

Carr, T. D. and Feehan, R. P. and Hall, M. N. and Rüegg, M. A. and Shantz, L. M.. (2015) Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis, Vol. 36, H. 4. S. 487-497.

Domi, Teuta and Porrello, Emanuela and Velardo, Daniele and Capotondo, Alessia and Biffi, Alessandra and Tonlorenzi, Rossana and Amadio, Stefano and Ambrosi, Alessandro and Miyagoe-Suzuki, Yuko and Takeda, Shin'ichi and Ruegg, Markus A. and Previtali, Stefano Carlo. (2015) Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A. Skeletal muscle, Vol. 5, H. 1. S. 30.

Lopez, Rubén J. and Mosca, Barbara and Treves, Susan and Maj, Marcin and Bergamelli, Leda and Calderon, Juan C. and Bentzinger, C. Florian and Romanino, Klaas and Hall, Michael N. and Rüegg, Markus A. and Delbono, Osvaldo and Caputo, Carlo and Zorzato, Francesco. (2015) Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. The biochemical journal, Vol. 466, H. 1. S. 123-135.

Ma, S. and Venkatesh, A. and Langellotto, F. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Experimental eye research, Vol. 135. S. 1-13.

Martin, Sally K. and Fitter, Stephen and Dutta, Ankit K. and Matthews, Mary P. and Walkley, Carl R. and Hall, Michael N. and Ruegg, Markus A. and Gronthos, Stan and Zannettino, Andrew C. W.. (2015) Brief Report: The Differential Roles of mTORC1 and mTORC2 in Mesenchymal Stem Cell Differentiation. Stem cells, Vol. 33, H. 4. S. 1359-1365.

Ormazabal, Maitea Guridi. Skeletal muscle mTORC1 regulates whole-body metabolism. 2015, PhD Thesis, University of Basel, Faculty of Science.

Tintignac, Lionel A. and Brenner, Hans-Rudolf and Rüegg, Markus A.. (2015) Mechanisms Regulating Neuromuscular Junction Development and Function and Causes of Muscle Wasting. Physiological reviews, Vol. 95, no. 3. S. 809-852.

Venkatesh, A. and Ma, S. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. The Journal of clinical investigation, Vol. 125, H. 4. S. 1446-1458.

Zhang, Yina and Lin, Shuo and Karakatsani, Andromachi and Rüegg, Markus A. and Kröger, Stephan. (2015) Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles. The European journal of neuroscience, Vol. 41, H. 1. S. 69-78.

2014

Chen, J. and Tu, X. and Esen, E. and Joeng, K. S. and Lin, C. and Arbeit, J. M. and Rüegg, M. A. and Hall, M. N. and Ma, L. and Long, F.. (2014) WNT7B promotes bone formation in part through mTORC1. PLoS genetics, Vol. 10, H. 1 , e1004145.

Chou, Po-Chien and Oh, Won Jun and Wu, Chang-Chih and Moloughney, Joseph and Rüegg, Markus A. and Hall, Michael N. and Jacinto, Estela and Werlen, Guy. (2014) Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development. Journal of immunology, Vol. 193, H. 3. S. 1162-1170.

Grahammer, F. and Haenisch, N. and Steinhardt, F. and Sander, L. and Roerden, M. and Arnold, F. and Cordts, T. and Wanner, N. and Reichardt, W. and Kerjaschki, D. and Ruegg, M. A. and Hall, M. N. and Moulin, P. and Busch, H. and Boerries, M. and Walz, G. and Artunc, F. and Huber, T. B.. (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, H. 27 , E2817-E2826.

Hettwer, Stefan and Lin, Shuo and Kucsera, Stefan and Haubitz, Monika and Oliveri, Filippo and Fariello, Ruggero G. and Ruegg, Markus A. and Vrijbloed, Jan W.. (2014) Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction. PLoS one, Vol. 9, H. 2 , e88739.

Kleinert, Maximilian and Sylow, Lykke and Fazakerley, Daniel J. and Krycer, James R. and Thomas, Kristen C. and Oxbøll, Anne-Julie and Jordy, Andreas B. and Jensen, Thomas E. and Yang, Guang and Schjerling, Peter and Kiens, Bente and James, David E. and Ruegg, Markus A. and Richter, Erik A.. (2014) Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo. Molecular metabolism, Vol. 3, H. 6. S. 630-641.

Lebrun-Julien, F. and Bachmann, L. and Norrmén, C. and Trötzmüller, M. and Köfeler, H. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination. Journal of neuroscience, Vol. 34, H. 25. S. 8432-8448.

Miloslavski, Rachel and Cohen, Elad and Avraham, Adam and Iluz, Yifat and Hayouka, Zvi and Kasir, Judith and Mudhasani, Rajini and Jones, Stephen N. and Cybulski, Nadine and Rüegg, Markus A. and Larsson, Ola and Gandin, Valentina and Rajakumar, Arjuna and Topisirovic, Ivan and Meyuhas, Oded. (2014) Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. Journal of molecular cell biology, Vol. 6, H. 3. S. 255-266.

Norrmén, C. and Figlia, G. and Lebrun-Julien, F. and Pereira, J. A. and Trötzmüller, M. and Köfeler, H. C. and Rantanen, V. and Wessig, C. and van Deijk, A. F. and Smit, A. B. and Verheijen, M. G. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells. Cell reports, Vol. 9, H. 2. S. 646-660.

Olivieri, Stefano. Biosynthesis and release of brain-derived neurotrophic factor : a study using neurons derived from embryonic stem cells. 2014, PhD Thesis, University of Basel, Faculty of Science.

Steiner, Esther and Enzmann, Gaby U. and Lyck, Ruth and Lin, Shuo and Rüegg, Markus A. and Kröger, Stephan and Engelhardt, Britta. (2014) The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell & tissue research, Vol. 358, H. 2. S. 465-479.

Zhang, Lianjun and Tschumi, Benjamin O. and Corgnac, Stéphanie and Rüegg, Markus A. and Hall, Michael N. and Mach, Jean-Pierre and Romero, Pedro and Donda, Alena. (2014) Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function. Journal of immunology, Vol. 193, H. 4. S. 1759-1765.

2013

Bentzinger, C. Florian and Lin, Shuo and Romanino, Klaas and Castets, Perrine and Guridi, Maitea and Summermatter, Serge and Handschin, Christoph and Tintignac, Lionel A. and Hall, Michael N. and Rüegg, Markus A.. (2013) Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal muscle, Vol. 3, H. 1 , 6.

Castets, P. and Lin, S. and Rion, N. and Di Fulvio, S. and Romanino, K. and Guridi, M. and Frank, S. and Tintignac, L. A. and Sinnreich, M. and Ruegg, M. A.. (2013) Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell metabolism, Vol. 17, H. 5. S. 731-744.

Castets, Perrine and Rüegg, Markus A.. (2013) MTORC1 determines autophagy through ULK1 regulation in skeletal muscle. Autophagy, Vol. 9, H. 9 , S. 1435 - 1437.

Cloëtta, Dimitri and Thomanetz, Venus and Baranek, Constanze and Lustenberger, Regula M. and Lin, Shuo and Oliveri, Filippo and Atanasoski, Suzana and Rüegg, Markus A.. (2013) Inactivation of mTORC1 in the Developing Brain Causes Microcephaly and Affects Gliogenesis. Journal of neuroscience, Vol. 33, H. 18. S. 7799-7810.

Song, Jian and Lokmic, Zerina and Lämmermann, Tim and Rolf, Julia and Wu, Chuan and Zhang, Xueli and Hallmann, Rupert and Hannocks, Melanie-Jane and Horn, Nathalie and Ruegg, Markus A. and Sonnenberg, Arnoud and Georges-Labouesse, Elisabeth and Winkler, Thomas H. and Kearney, John F. and Cardell, Susanna and Sorokin, Lydia. (2013) Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 31 , S. E2915-2924.

Thomanetz, Venus and Angliker, Nico and Cloëtta, Dimitri and Lustenberger, Regula M. and Schweighauser, Manuel and Oliveri, Filippo and Suzuki, Noboru and Rüegg, Markus A.. (2013) Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology. The journal of cell biology, Vol. 201, H. 2. S. 293-308.

2012

Blättler, Sharon M. and Cunningham, John T. and Verdeguer, Francisco and Chim, Helen and Haas, Wilhelm and Liu, Huifei and Romanino, Klaas and Rüegg, Markus A. and Gygi, Steven P. and Shi, Yang and Puigserver, Pere. (2012) Yin yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. Cell metabolism, Vol. 15, H. 4. S. 505-517.

Blättler, Sharon M. and Verdeguer, Francisco and Liesa, Marc and Cunningham, John T. and Vogel, Rutger O. and Chim, Helen and Liu, Huifei and Romanino, Klaas and Shirihai, Orian S. and Vazquez, Francisca and Rüegg, Markus A. and Shi, Yang and Puigserver, Pere. (2012) Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Molecular and cellular biology, Vol. 32, H. 16. S. 3333-3346.

Haefeli, Roman Hans. Molecular effects of Idebenone. 2012, PhD Thesis, University of Basel, Faculty of Science.

Hagiwara, Asami and Cornu, Marion and Cybulski, Nadine and Polak, Pazit and Betz, Charles and Trapani, Francesca and Terracciano, Luigi and Heim, Markus H. and Rüegg, Markus A. and Hall, Michael N.. (2012) Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell metabolism, Vol. 15, H. 5. S. 725-738.

Lustenberger, Regula Maria. The role of raptor during brain development and in adult forebrain neurons. 2012, PhD Thesis, University of Basel, Faculty of Science.

Meinen, Sarina and Lin, Shuo and Ruegg, Markus A.. (2012) Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A). Skeletal muscle, Vol. 2, H. 1. S. 18.

Meinen, Sarina and Lin, Shuo and Rüegg, Markus A. and Punga, Anna Rostedt. (2012) Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS. PLoS one, Vol. 7, H. 8 , e44148.

Punga, Anna Rostedt and Ruegg, Markus A.. (2012) Signaling and aging at the neuromuscular synapse : lessons learnt from neuromuscular diseases. Current opinion in pharmacology, Vol. 12, H. 3. S. 340-346.

Reinhard, Judith. The function of Copine 6 in the brain. 2012, PhD Thesis, University of Basel, Faculty of Science.

Romanino, Klaas Emilio Antonius Anna. The role of mTOR complex 1 in skeletal muscle. 2012, PhD Thesis, University of Basel, Faculty of Science.

Steiner, Esther and Enzmann, Gaby U. and Lin, Shuo and Ghavampour, Sharang and Hannocks, Melanie-Jane and Zuber, Benoît and Rüegg, Markus A. and Sorokin, Lydia and Engelhardt, Britta. (2012) Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia, Vol. 60, No. 11. S. 1646-1659.

Thomanetz, Venus. mTORC2 controls neuron size and Purkinje cell morphology independent of mTORC1. 2012, PhD Thesis, University of Basel, Faculty of Science.

2011

Baldo, Barbara. Innovative approaches to monitor mutant huntingtin and to facilitate its degradation in Huntington's disease models. 2011, PhD Thesis, University of Basel, Faculty of Science.

Escher, Claudia Andrea. Proteomic profiling of Duchenne muscular dystrophy : protein patterns and candidate markers of disease. 2011, PhD Thesis, University of Basel, Faculty of Science.

Godel, M. and Hartleben, B. and Herbach, N. and Liu, S. and Zschiedrich, S. and Lu, S. and Debreczeni-Mor, A. and Lindenmeyer, M. T. and Rastaldi, M. -P. and Hartleben, G. and Wiech, T. and Fornoni, A. and Nelson, R. G. and Kretzler, M. and Wanke, R. and Pavenstadt, H. and Kerjaschki, D. and Cohen, C. D. and Hall, M. N. and Ruegg, M. A. and Inoki, K. and Walz, G. and Huber, T. B.. (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. The Journal of clinical investigation, Vol. 121, H. 6. S. 2197-2209.

Inoki, K. and Mori, H. and Wang, J. and Suzuki, T. and Hong, S. and Yoshida, S. and Blattner, S. M. and Ikenoue, T. and Ruegg, M. A. and Hall, M. N. and Kwiatkowski, D. J. and Rastaldi, M. P. and Huber, T. B. and Kretzler, M. and Holzman, L. B. and Wiggins, R. C. and Guan, K. -L.. (2011) mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. The Journal of clinical investigation, Vol. 121, H. 6. S. 2181-2196.

Laxhmi Chellappa, Sarah. Circadian and ultradian NREM-REM sleep modulation of dream recall : effects of age and spectral activity. 2011, PhD Thesis, University of Basel, Faculty of Science.

Meinen, Sarina and Lin, Shuo and Thurnherr, Raphael and Erb, Michael and Meier, Thomas and Rüegg, Markus A.. (2011) Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO molecular medicine, Vol. 3, H. 8. S. 465-479.

Punga, A. R. and Lin, S. and Oliveri, F. and Meinen, S. and Ruegg, M. A.. (2011) Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice. Experimental neurology, Vol. 230, H. 2. S. 207-217.

Punga, A. R. and Maj, M. and Lin, S. and Meinen, S. and Ruegg, M. A.. (2011) MuSK levels differ between adult skeletal muscles and influence postsynaptic plasticity. The European journal of neuroscience, Vol. 33, H. 5. S. 890-898.

Rieker, Claus and Dev, Kumlesh K. and Lehnhoff, Katja and Barbieri, Samuel and Ksiazek, Iwona and Kauffmann, Sabine and Danner, Simone and Schell, Heinrich and Boden, Cindy and Ruegg, Markus A. and Kahle, Philipp J. and van der Putten, Herman and Shimshek, Derya R.. (2011) Neuropathology in mice expressing mouse alpha-synuclein. PLoS one, Vol. 6, H. 9 , e24834.

Romanino, Klaas and Mazelin, Laetitia and Albert, Verena and Conjard-Duplany, Agnès and Lin, Shuo and Bentzinger, C. Florian and Handschin, Christoph and Puigserver, Pere and Zorzato, Francesco and Schaeffer, Laurent and Gangloff, Yann-Gaël and Rüegg, Markus A.. (2011) Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 51. S. 20808-20813.

Shende, P. and Plaisance, I. and Morandi, C. and Pellieux, C. and Berthonneche, C. and Zorzato, F. and Krishnan, J. and Lerch, R. and Hall, M. N. and Ruegg, M. A. and Pedrazzini, T. and Brink, M.. (2011) Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation, Vol. 123, H. 10. S. 1073-1082.

Yazdani Shektaei, Morteza. Disease modelling of a human neurodevelopmental disorder using mouse embryonic stem cells. 2011, PhD Thesis, University of Basel, Faculty of Science.

2010

Cloëtta, Dimitri Yves Reto. A conditional mouse model for the characterization of mTORC1 function in muscle and brain. 2010, PhD Thesis, University of Basel, Faculty of Science.

Escher, Claudia and Lochmüller, Hanns and Fischer, Dirk and Frank, Stephan and Reimann, Jens and Walter, Maggie C. and Ehrat, Markus and Ruegg, Markus A. and Gygax, Daniel. (2010) Reverse protein arrays as novel approach for protein quantification in muscular dystrophies. Neuromuscular disorders, Vol. 20. S. 302-309.

Kriz, Alexander. Copine 6, a novel calcium sensor translating synaptic activity into spine plasticity : or, "Copine 6 a brainsporter in action". 2010, PhD Thesis, University of Basel, Faculty of Science.

Miglino, Nicola Romolo. Novel molecular pathologies in asthma and COPD. 2010, PhD Thesis, University of Basel, Faculty of Science.

Rüegg, Markus A. and Glass, David J.. (2010) Molecular mechanisms and treatment options for muscle wasting eiseases. Annual review of pharmacology and toxicology, Vol. 51. S. 373-395.

2009

Bentzinger, Conrad Florian. Function of mTOR complex 1 and 2 in skeletal muscle. 2009, PhD Thesis, University of Basel, Faculty of Science.

Clavaguera, Florence. Initiation and spreading of Tau pathology. is β-Amyloid the only key? 2009, PhD Thesis, University of Basel, Faculty of Science.

Cybulski, N. and Polak, P. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2009) mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, H. 24. S. 9902-9907.

Egler, Viviane. A combinatorial preclinical in vitro strategy against human glioblastoma cells. specific targeting of protein kinases, histone deacetylases and glycolysis. 2009, PhD Thesis, University of Basel, Faculty of Science.

Erb, M. and Meinen, S. and Barzaghi, P. and Sumanovski, L. T. and Courdier-Fruh, I. and Ruegg, M. A. and Meier, T.. (2009) Omigapil ameliorates the pathology of muscle dystrophy caused by laminin-α2 deficiency. Journal of pharmacology and experimental therapeutics, Vol. 331, H. 3. S. 787-795.

Huze, C. and Bauche, S. and Richard, P. and Chevessier, F. and Goillot, E. and Gaudon, K. and Ben Ammar, A. and Chaboud, A. and Grosjean, I. and Lecuyer, H. -A. and Bernard, V. and Rouche, A. and Alexandri, N. and Kuntzer, T. and Fardeau, M. and Fournier, E. and Brancaccio, A. and Ruegg, M. A. and Koenig, J. and Eymard, B. and Schaeffer, L. and Hantai, D.. (2009) Identification of an agrin mutation that causes congenital myasthenia and affects synapse function. American journal of human genetics, Vol. 85, H. 2. S. 155-167.

Patursky-Polischuk, I. and Stolovich-Rain, M. and Hausner-Hanochi, M. and Kasir, J. and Cybulski, N. and Avruch, J. and Ruegg, M. A. and Hall, M. N. and Meyuhas, O.. (2009) The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Molecular and cellular biology, Vol. 29, H. 3. S. 640-649.

Risson, Valérie and Mazelin, Laetitia and Roceri, Mila and Sanchez, Hervé and Moncollin, Vincent and Corneloup, Claudine and Richard-Bulteau, Hélène and Vignaud, Alban and Baas, Dominique and Defour, Aurélia and Freyssenet, Damien and Tanti, Jean-François and Le-Marchand-Brustel, Yannick and Ferrier, Bernard and Conjard-Duplany, Agnès and Romanino, Klaas and Bauché, Stéphanie and Hantaï, Daniel and Mueller, Matthias and Kozma, Sara C. and Thomas, George and Rüegg, Markus A. and Ferry, Arnaud and Pende, Mario and Bigard, Xavier and Koulmann, Nathalie and Schaeffer, Laurent and Gangloff, Yann-Gaël. (2009) Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy. The Journal of cell biology, Vol. 187, H. 6. S. 859-874.

Willmann, R. and Possekel, S. and Dubach-Powell, J. and Meier, T. and Ruegg, M. A.. (2009) Mammalian animal models for Duchenne muscular dystrophy. Neuromuscular Disorders, Vol. 19, H. 4. S. 241-249.

2008

Annaheim, Christine. Untersuchungen über die funktionelle Rolle des Neurotrophinrezeptors p75 basierend auf embryonalen Stammzellen der Maus. 2008, PhD Thesis, University of Basel, Faculty of Science.

Bentzinger, C. F. and Romanino, K. and Cloetta, D. and Lin, S. and Mascarenhas, J. B. and Oliveri, F. and Xia, J. and Casanova, E. and Costa, C. F. and Brink, M. and Zorzato, F. and Hall, M. N. and Ruegg, M. A.. (2008) Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, Vol. 8, H. 5. S. 411-424.

Giacometti, Emanuela. Epigenetic and central nervous system function : insights from the study of the rett syndrome mouse model. 2008, PhD Thesis, University of Basel, Faculty of Science.

Heitz, Stéphane. Neuronal death mechanisms in cerebellar Purkinje cells. 2008, PhD Thesis, University of Basel, Faculty of Science.

Lin, S. and Landmann, L. and Ruegg, M. A. and Brenner, H. R.. (2008) The role of nerve- versus muscle-derived factors in mammalian neuromuscular junction formation. Journal of neuroscience, Vol. 28, H. 13. S. 3333-3340.

Lin, S. and Maj, M. and Bezakova, G. and Magyar, J. P. and Brenner, H. R. and Ruegg, M. A.. (2008) Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice. Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, H. 32. S. 11406-11411.

Maj, Marcin. Functional characterization of MuSK, receptor tyrosine kinase required for the formation and the maintenance of nerve-muscle synapses : "in vivo" and "in vitro" approaches. 2008, PhD Thesis, University of Basel, Faculty of Science.

Polak, P. and Cybulski, N. and Feige, J. N. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2008) Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration. Cell Metabolism, Vol. 8, H. 5. S. 399-410.

Reiterer, V. and Maier, S. and Sitte, H. H. and Kriz, A. and Ruegg, M. A. and Hauri, H. P. and Freissmuth, M. and Farhan, H.. (2008) Sec24- and ARFGAP1-dependent trafficking of GABA transporter-1 is a prerequisite for correct axonal targeting. Journal of neuroscience, Vol. 28, H. 47. S. 12453-12464.

Sivasankaran, Balasubramanian. The role of NOTCH2 gene in human malignant glial brain tumours. 2008, PhD Thesis, University of Basel, Faculty of Science.

Zhang, Yan-Ping. Optical analysis of synaptic plasticity in rat hippocampus. 2008, PhD Thesis, University of Basel, Faculty of Science.

2007

Camilleri, A. A. and Willmann, R. and Sadasivam, G. and Lin, S. and Ruegg, M. A. and Gesemann, M. and Fuhrer, C.. (2007) Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors. BMC Neuroscience, Vol. 8 , 46.

Cueni, Lucius D.. Low-voltage-activated Ca²+ channels. from burst generators to Ca²+ sources in thalamic oscillatory activity. 2007, PhD Thesis, University of Basel, Faculty of Science.

Failly, Mike. Combinatorial strategy using protein kinase inhibitors and a cytotoxic compound for highly resistant glioblastoma cells : "in vitro studies". 2007, PhD Thesis, University of Basel, Faculty of Science.

Hausser, H. -J. and Ruegg, M. A. and Brenner, R. E. and Ksiazek, I.. (2007) Agrin is highly expressed by chondrocytes and is required for normal growth. Histochemistry and cell biology, Vol. 127, H. 4. S. 363-374.

Ksiazek, Iwona and Burkhardt, Constanze and Lin, Shuo and Seddik, Riad and Maj, Marcin and Bezakova, Gabriela and Jucker, Mathias and Arber, Silvia and Caroni, Pico and Sanes, Joshua R. and Bettler, Bernhard and Ruegg, Markus A.. (2007) Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. Journal of neuroscience, Vol. 27, H. 27. S. 7183-7195.

Meinen, S. and Barzaghi, P. and Lin, S. and Lochmuller, H. and Ruegg, M. A.. (2007) Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages. The Journal of cell biology, Vol. 176, H. 7. S. 979-993.

Plachta, N. and Annaheim, C. and Bissiere, S. and Lin, S. and Ruegg, M. and Hoving, S. and Muller, D. and Poirier, F. and Bibel, M. and Barde, Y. -A.. (2007) Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nature neuroscience, Vol. 10, H. 6. S. 712-719.

Ruiz, Christian. Identification and validation of novel amplification target genes in human breast cancer. 2007, PhD Thesis, University of Basel, Faculty of Science.

2006

Annies, M. and Bittcher, G. and Ramseger, R. and Loschinger, J. and Woll, S. and Porten, E. and Abraham, C. and Ruegg, M. A. and Kroger, S.. (2006) Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites. Molecular and cellular neuroscience, Vol. 31, H. 3. S. 515-524.

Bittcher, Godela. The role of transmembrane agrin in reorganizing the cytoskeleton in neurons and non-neuronal cells. 2006, PhD Thesis, University of Basel, Faculty of Science.

Bolmont, Tristan. Mechanisms underlying the initiation of cerebral betaamyloidosis and neurofibrillary tau pathology : new insights form transgenic mice. 2006, PhD Thesis, University of Basel, Faculty of Science.

Ermini, Florian V.. Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease. 2006, PhD Thesis, University of Basel, Faculty of Science.

Galic, Milos. Regulation of dendritic spine morphogenesis and synapse formation by copines. 2006, PhD Thesis, University of Basel, Faculty of Science.

Güntert, Andreas. Characterization of amyloid-ß and other proteins related to Alzheimer's disease, their role in neurodegeneration and biomarker discovery. 2006, PhD Thesis, University of Basel, Faculty of Science.

Jokic, N. and Gonzalez de Aguilar, J. -L. and Dimou, L. and Lin, S. and Fergani, A. and Ruegg, M. A. and Schwab, M. E. and Dupuis, L. and Loeffler, J. -P.. (2006) The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO reports, Vol. 7, H. 11. S. 1162-1167.

Meinen, S. and Ruegg, M. A.. (2006) Congenital muscular dystrophy: mini-agrin delivers in mice. Gene Therapy, Vol. 13, H. 11. S. 869-870.

Possekel, S. and Meier, T. and Ruegg, M. A.. (2006) Peripheral signaling pathways involved in muscle loss. In: Pharmacotherapy of cachexia. Boca Raton, FL, USA, S. 543-564.

Ruegg, M. A.. (2006) Commonalities and differences in muscular dystrophies : mechanisms and molecules involved in merosin-deficient congenital muscular dystrophy. In: Molecular mechanisms of muscular dystrophies. Georgetown, Tex., S. 74-81.

Scotton, P. and Bleckmann, D. and Stebler, M. and Sciandra, F. and Brancaccio, A. and Meier, T. and Stetefeld, J. and Ruegg, M. A.. (2006) Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin. Journal of Biological Chemistry, Vol. 281, H. 48. S. 36835-36845.

Scotton, Patrick. New approaches to identify interactors of MuSK, a receptor tyrosine kinase required for the formation of the nerve-muscle synapse. 2006, PhD Thesis, University of Basel, Faculty of Science.

2005

Bentzinger, C. F. and Barzaghi, P. and Lin, S. and Ruegg, M. A.. (2005) Overexpression of mini-agrin in skeletal muscle increases muscle integrity and regenerative capacity in laminin-alpha2-deficient mice. The FASEB Journal, Vol. 19, H. 8. S. 934-942.

Madhavan, R. and Zhao, X. T. and Ruegg, M. A. and Peng, H. B.. (2005) Tyrosine phosphatase regulation of MuSK-dependent acetylcholine receptor clustering. Molecular and cellular neuroscience, Vol. 28, H. 3. S. 403-416.

Mascarenhas, J. B. and Ruegg, M. A. and Sasaki, T. and Eble, J. A. and Engel, J. and Stetefeld, J.. (2005) Structure and laminin-binding specificity of the NtA domain expressed in eukaryotic cells. Matrix Biology, Vol. 23, H. 8. S. 507-513.

Meinen, Sarina. Artificial restoration of the linkage between laminin and dystroglycan ameliorates the disease progression of MDC1A muscular dystrophy at all stages. 2005, PhD Thesis, University of Basel, Faculty of Science.

Ruegg, M. A.. (2005) Organization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve-muscle synapse. Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, H. 16. S. 5643-5644.

Sadasivam, G. and Willmann, R. and Lin, S. and Erb-Vogtli, S. and Kong, X. C. and Ruegg, M. A. and Fuhrer, C.. (2005) Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors. Journal of neuroscience, Vol. 25, H. 45. S. 10479-10493.

Smirnov, S. P. and Barzaghi, P. and McKee, K. K. and Ruegg, M. A. and Yurchenco, P. D.. (2005) Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering. Journal of Biological Chemistry, Vol. 280, H. 50. S. 41449-41457.

Stetefeld, J. and Ruegg, M. A.. (2005) Structural and functional diversity generated by alternative mRNA splicing. Trends in biochemical sciences, Vol. 30, H. 9. S. 515-521.

2004

Jacinto, E. and Loewith, R. and Schmidt, A. and Lin, S. and Ruegg, M. A. and Hall, A. and Hall, M. N.. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology, Vol. 6, H. 11. S. 1122-1128.

Kong, X. C. and Barzaghi, P. and Ruegg, M. A.. (2004) Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference. EMBO reports, Vol. 5, H. 2. S. 183-188.

Ruegg, M. A. and McMahan, U. J.. (2004) Agrin. In: Encyclopedia of Neuroscience. Amsterdam.

Stetefeld, J. and Alexandrescu, A. T. and Maciejewski, M. W. and Jenny, M. and Rathgeb-Szabo, K. and Schulthess, T. and Landwehr, R. and Frank, S. and Ruegg, M. A. and Kammerer, R. A.. (2004) Modulation of agrin function by alternative splicing and Ca2+ binding. Structure: with folding and design, Vol. 12, H. 3. S. 503-515.

2003

Bartoccioni, E. and Marino, M. and Evoli, A. and Ruegg, M. A. and Scuderi, F. and Provenzano, C.. (2003) Identification of disease-specific autoantibodies in seronegative myasthenia gravis. Annals of the New York Academy of Sciences, Vol. 998. S. 356-358.

Bezakova, G. and Ruegg, M. A.. (2003) New insights into the roles of agrin. Nature reviews. Molecular cell biology, Vol. 4, H. 4. S. 295-308.

De Paola, Vincenzo. Pre-synaptic terminal dynamics in the hippocampus. 2003, PhD Thesis, University of Basel, Faculty of Science.

Eusebio, A. and Oliveri, F. and Barzaghi, P. and Ruegg, M. A.. (2003) Expression of mouse agrin in normal, denervated and dystrophic muscle. Neuromuscular Disorders, Vol. 13, H. 5. S. 408-415.

Guo, L. T. and Zhang, X. U. and Kuang, W. and Xu, H. and Liu, L. A. and Vilquin, J. -T. and Miyagoe-Suzuki, Y. and Takeda, S. and Ruegg, M. A. and Wewer, U. M. and Engvall, E.. (2003) Laminin alpha2 deficiency and muscular dystrophy : genotype-phenotype correlation in mutant mice. Neuromuscular Disorders, Vol. 13, H. 3. S. 207-215.

Kong, Xian Chu. RNA interference: a new tool to study gene functions in adult mammalian muscle "in vivo". 2003, PhD Thesis, University of Basel, Faculty of Science.

Mascarenhas, J. B. and Ruegg, M. A. and Winzen, U. and Halfter, W. and Engel, J. and Stetefeld, J.. (2003) Mapping of the laminin-binding site of the N-terminal agrin domain (NtA). The EMBO journal, Vol. 22, H. 3. S. 529-536.

2002

Abicht, A. and Stucka, R. and Schmidt, C. and Briguet, A. and Hopfner, S. and Song, I. -H. and Pongratz, D. and Muller-Felber, W. and Ruegg, M. A. and Lochmuller, H.. (2002) A newly identified chromosomal microdeletion and an N-box mutation of the AChR epsilon gene cause a congenital myasthenic syndrome. Brain, Vol. 125, H. 5. S. 1005-1013.

Bixby, J. L. and Baerwald-De la Torre, K. and Wang, C. and Rathjen, F. G. and Ruegg, M. A.. (2002) A neuronal inhibitory domain in the N-terminal half of agrin. Journal of neurobiology, Vol. 50, H. 2. S. 164-179.

Pun, S. and Sigrist, M. and Santos, A. F. and Ruegg, M. A. and Sanes, J. R. and Jessell, T. M. and Arber, S. and Caroni, P.. (2002) An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron, Vol. 34, H. 3. S. 357-370.

2001

Alexandrescu, A. T. and Maciejewski, M. W. and Ruegg, M. A. and Engel, J. and Kammerer, R. A.. (2001) 1H, 13C and 15N backbone assignments for the C-terminal globular domain of agrin. Journal of biomolecular NMR, Vol. 20, H. 3. S. 295-296.

Moll, J. and Barzaghi, P. and Lin, S. and Bezakova, G. and Lochmuller, H. and Engvall, E. and Muller, U. and Ruegg, M. A.. (2001) An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy. Nature, Vol. 413 , H. 6853. S. 302-307.

Neumann, F. R. and Bittcher, G. and Annies, M. and Schumacher, B. and Kroger, S. and Ruegg, M. A.. (2001) An alternative amino-terminus expressed in the central nervous system converts agrin to a type II transmembrane protein. Molecular and cellular neuroscience, Vol. 17, H. 1. S. 208-225.

Ruegg, M. A.. (2001) Molecules involved in the formation of synaptic connections in muscle and brain. Matrix Biology, Vol. 20, H. 1. S. 3-12.

Stetefeld, J. and Jenny, M. and Schulthess, T. and Landwehr, R. and Schumacher, B. and Frank, S. and Ruegg, M. A. and Engel, J. and Kammerer, R. A.. (2001) The laminin-binding domain of agrin is structurally related to N-TIMP-1. Nature Structural biology, Vol. 8, H. 8. S. 705-709.

2000

Briguet, A. and Ruegg, M. A.. (2000) The Ets transcription factor GABP is required for postsynaptic differentiation in vivo. Journal of neuroscience, Vol. 20, H. 16. S. 5989-5996.

Halfter, W. and Dong, S. and Schurer, B. and Osanger, A. and Schneider, W. and Ruegg, M. and Cole, G. J.. (2000) Composition, synthesis, and assembly of the embryonic chick retinal basal lamina. Developmental biology, Vol. 220, H. 2. S. 111-128.

Meier, T. and Ruegg, M. A.. (2000) The Role of Dystroglycan and Its Ligands in Physiology and Disease. News in physiological sciences, Vol. 15. S. 255-259.

Sommer, B. and Barbieri, S. and Hofele, K. and Wiederhold, K. and Probst, A. and Mistl, C. and Danner, S. and Kauffmann, S. and Spooren, W. and Tolnay, M. and Bilbe, G. and Kafmann, S. and Caromi, P. and Ruegg, M. A.. (2000) Mouse models of alpha-synucleinopathy and Lewy pathology. Experimental gerontology, Vol. 35, no. 9-10. S. 1389-1403.

van der Putten, H. and Wiederhold, K. H. and Probst, A. and Barbieri, S. and Mistl, C. and Danner, S. and Kauffmann, S. and Hofele, K. and Spooren, W. P. and Ruegg, M. A. and Lin, S. and Caroni, P. and Sommer, B. and Tolnay, M. and Bilbe, G.. (2000) Neuropathology in mice expressing human alpha-synuclein. Journal of neuroscience, Vol. 20, H. 16. S. 6021-6029.

1999

Kammerer, R. A. and Schulthess, T. and Landwehr, R. and Schumacher, B. and Lustig, A. and Yurchenco, P. D. and Ruegg, M. A. and Engel, J. and Denzer, A. J.. (1999) Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin gamma1 chain. The EMBO journal, Vol. 18, H. 23. S. 6762-6770.

1998

Denzer, A. J. and Schulthess, T. and Fauser, C. and Schumacher, B. and Kammerer, R. A. and Engel, J. and Ruegg, M. A.. (1998) Electron microscopic structure of agrin and mapping of its binding site in laminin-1. The EMBO journal, Vol. 17, H. 2. S. 335-343.

Gesemann, M. and Brancaccio, A. and Schumacher, B. and Ruegg, M. A.. (1998) Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue. Journal of Biological Chemistry, Vol. 273, H. 1. S. 600-605.

Groffen, A. J. and Ruegg, M. A. and Dijkman, H. and van de Velden, T. J. and Buskens, C. A. and van den Born, J. and Assmann, K. J. and Monnens, L. A. and Veerkamp, J. H. and van den Heuvel, L. P.. (1998) Agrin is a major heparan sulfate proteoglycan in the human glomerular basement membrane. Journal of histochemistry and cytochemistry, Vol. 46, H. 1. S. 19-27.

Meier, T. and Marangi, P. A. and Moll, J. and Hauser, D. M. and Brenner, H. R. and Ruegg, M. A.. (1998) A minigene of neural agrin encoding the laminin-binding and acetylcholine receptor-aggregating domains is sufficient to induce postsynaptic differentiation in muscle fibres. The European journal of neuroscience, Vol. 10, H. 10. S. 3141-3152.

Meier, T. and Ruegg, M. A. and Wallace, B. G.. (1998) Muscle-specific agrin isoforms reduce phosphorylation of AChR gamma and delta subunits in cultured muscle cells. Molecular and cellular neuroscience, Vol. 11, H. 4. S. 206-216.

Nawrotzki, R. and Loh, N. Y. and Ruegg, M. A. and Davies, K. E. and Blake, D. J.. (1998) Characterisation of alpha-dystrobrevin in muscle. Journal of cell science, Vol. 111, H. 17. S. 2595-2605.

Ruegg, M. A. and Bixby, J. L.. (1998) Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction. Trends in neurosciences, Vol. 21, H. 1. S. 22-27.

Sieb, J. P. and Dorfler, P. and Tzartos, S. and Wewer, U. M. and Ruegg, M. A. and Meyer, D. and Baumann, I. and Lindemuth, R. and Jakschik, J. and Ries, F.. (1998) Congenital myasthenic syndromes in two kinships with end-plate acetylcholine receptor and utrophin deficiency. Neurology, Vol. 50, H. 1. S. 54-61.

1997

Campagna, J. A. and Ruegg, M. A. and Bixby, J. L.. (1997) Evidence that agrin directly influences presynaptic differentiation at neuromuscular junctions in vitro. The European journal of neuroscience, Vol. 9, H. 11. S. 2269-2283.

Denzer, A. J. and Brandenberger, R. and Gesemann, M. and Chiquet, M. and Ruegg, M. A.. (1997) Agrin binds to the nerve-muscle basal lamina via laminin. The Journal of cell biology, Vol. 137, H. 3. S. 671-683.

Denzer, A. J. and Hauser, D. M. and Gesemann, M. and Ruegg, M. A.. (1997) Synaptic differentiation : the role of agrin in the formation and maintenance of the neuromuscular junction. Cell & [and] tissue research, Vol. 290, H. 2. S. 357-365.

Meier, T. and Hauser, D. M. and Chiquet, M. and Landmann, L. and Ruegg, M. A. and Brenner, H. R.. (1997) Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers. Journal of neuroscience, Vol. 17, H. 17. S. 6534-6544.

1996

Gesemann, M. and Cavalli, V. and Denzer, A. J. and Brancaccio, A. and Schumacher, B. and Ruegg, M. A.. (1996) Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptor. Neuron, Vol. 16, H. 4. S. 755-767.

Jones, G. and Herczeg, A. and Ruegg, M. A. and Lichtsteiner, M. and Kroger, S. and Brenner, H. R.. (1996) Substrate-bound agrin induces expression of acetylcholine receptor epsilon-subunit gene in cultured mammalian muscle cells. Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, H. 12. S. 5985-5990.

Meier, T. and Gesemann, M. and Cavalli, V. and Ruegg, M. A. and Wallace, B. G.. (1996) AChR phosphorylation and aggregation induced by an agrin fragment that lacks the binding domain for alpha-dystroglycan. The EMBO journal, Vol. 15, H. 11. S. 2625-2631.

Ruegg, M. A.. (1996) Agrin, laminin beta 2 (s-laminin) and ARIA : their role in neuromuscular development. Current Opinion in Neurobiology, Vol. 6, H. 1. S. 97-103.

Yamada, H. and Denzer, A. J. and Hori, H. and Tanaka, T. and Anderson, L. V. and Fujita, S. and Fukuta-Ohi, H. and Shimizu, T. and Ruegg, M. A. and Matsumura, K.. (1996) Dystroglycan is a dual receptor for agrin and laminin-2 in Schwann cell membrane. Journal of biological chemistry, Vol. 271 , no. 38. S. 23418-23423.

1995

Brancaccio, A. and Ruegg, M. A. and Engel, J.. (1995) Cloning and sequencing of mouse skeletal muscle alpha-dystroglycan. Matrix biology, Vol. 14, H. 8. S. 681-685.

Campagna, J. A. and Ruegg, M. A. and Bixby, J. L.. (1995) Agrin is a differentiation-inducing "stop signal" for motoneurons in vitro. Neuron, Vol. 15, H. 6. S. 1365-1374.

Denzer, A. J. and Gesemann, M. and Schumacher, B. and Ruegg, M. A.. (1995) An amino-terminal extension is required for the secretion of chick agrin and its binding to extracellular matrix. The Journal of cell biology, Vol. 131, H. 6. S. 1547-1560.

Gesemann, M. and Denzer, A. J. and Ruegg, M. A.. (1995) Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site. The Journal of cell biology, Vol. 128, H. 4. S. 625-636.

1992

McMahan, U. J. and Horton, S. E. and Werle, M. J. and Honig, L. S. and Kroger, S. and Ruegg, M. A. and Escher, G.. (1992) Agrin isoforms and their role in synaptogenesis. Current opinion in cell biology, Vol. 4, H. 5. S. 869-874.

Ruegg, M. A. and Tsim, K. W. and Horton, S. E. and Kroger, S. and Escher, G. and Gensch, E. M. and McMahan, U. J.. (1992) The agrin gene codes for a family of basal lamina proteins that differ in function and distribution. Neuron, Vol. 8, H. 4. S. 691-699.

Tsim, K. W. and Ruegg, M. A. and Escher, G. and Kroger, S. and McMahan, U. J.. (1992) cDNA that encodes active agrin. Neuron, Vol. 8, H. 4. S. 677-689.

1991

Stoeckli, E. T. and Kuhn, T. B. and Duc, C. O. and Ruegg, M. A. and Sonderegger, P.. (1991) The axonally secreted protein axonin-1 is a potent substratum for neurite growth. The Journal of cell biology, Vol. 112, H. 3. S. 449-455.

1989

Ruegg, M. A. and Stoeckli, E. T. and Kuhn, T. B. and Heller, M. and Zuellig, R. and Sonderegger, P.. (1989) Purification of axonin-1, a protein that is secreted from axons during neurogenesis. The EMBO journal, Vol. 8, H. 1. S. 55-63.

Ruegg, M. A. and Stoeckli, E. T. and Lanz, R. B. and Streit, P. and Sonderegger, P.. (1989) A homologue of the axonally secreted protein axonin-1 is an integral membrane protein of nerve fiber tracts involved in neurite fasciculation. Journal of cell biology, 109, H. 5 (5). pp. 2363-2378.

Stoeckli, E. T. and Lemkin, P. F. and Kuhn, T. B. and Ruegg, M. A. and Heller, M. and Sonderegger, P.. (1989) Identification of proteins secreted from axons of embryonic dorsal-root-ganglia neurons. European journal of biochemistry, Vol. 180, H. 2. S. 249-258.

This list was generated on Sat Mar 25 03:55:21 2017 CET.