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Items where Division is "05 Faculty of Science > Departement Biozentrum > Growth & Development > Biochemistry (Hall)"

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Number of items at this level: 250.

17 May 2016

Swierczynska, Marta M. and Hall, Michael N.. (2016) eIF4A moonlights as an off switch for TORC1. The EMBO journal, 35 (10). pp. 1013-1014.

22 April 2016

Drägert, Katja and Bhattacharya, Indranil and Hall, Michael N. and Humar, Rok and Battegay, Edouard and Haas, Elvira. (2016) Basal mTORC2 activity and expression of its components display diurnal variation in mouse perivascular adipose tissue. Biochemical and biophysical research communications, 473 (1). pp. 317-322.

9 February 2016

Zhang, Lianjun and Tschumi, Benjamin O. and Lopez-Mejia, Isabel C. and Oberle, Susanne G. and Meyer, Marten and Samson, Guerric and Rüegg, Markus A. and Hall, Michael N. and Fajas, Lluis and Zehn, Dietmar and Mach, Jean-Pierre and Donda, Alena and Romero, Pedro. (2016) Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. Cell reports, 14 (5). pp. 1206-1217.

2 February 2016

Dazert, Eva and Colombi, Marco and Boldanova, Tujana and Moes, Suzette and Adametz, David and Quagliata, Luca and Roth, Volker and Terracciano, Luigi and Heim, Markus H. and Jenoe, Paul and Hall, Michael N.. (2016) Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient. Proceedings of the National Academy of Sciences of the United States of America, 113 (5). pp. 1381-1386.

January 2016

Shimobayashi, Mitsugu and Hall, Michael N.. (2016) Multiple amino acid sensing inputs to mTORC1. Cell research, 26 (1). pp. 7-20.

2016

Albert, Verena and Svensson, Kristoffer and Shimobayashi, Mitsugu and Colombi, Marco and Muñoz, Sergio and Jimenez, Veronica and Handschin, Christoph and Bosch, Fatima and Hall, Michael N.. (2016) mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO molecular medicine, 8 (3). pp. 232-246.

Fonseca, Bruno D. and Graber, Tyson E. and Hoang, Huy-Dung and González, Asier and Soukas, Alexandre A. and Hernández, Greco and Alain, Tommy and Swift, Stephanie L. and Weisman, Ronit and Meyer, Christian and Robaglia, Christophe and Avruch, Joseph and Hall, Michael N.. (2016) Evolution of TOR and Translation Control. In: Evolution of the Protein Synthesis Machinery and Its Regulation. Cham, pp. 327-412.

Guri, Yakir. mTORC2 promotes tumor growth via lipid synthesis. 2016, PhD Thesis, University of Basel, Faculty of Science.

Guri, Yakir and Hall, Michael N.. (2016) mTOR Signaling Confers Resistance to Targeted Cancer Drugs. Trends in Cancer, 2 (11). pp. 688-97.

Shende, Pankaj and Xu, Lifen and Morandi, Christian and Pentassuglia, Laura and Heim, Philippe and Lebboukh, Sonia and Berthonneche, Corinne and Pedrazzini, Thierry and Kaufmann, Beat A. and Hall, Michael N. and Rüegg, Markus A. and Brink, Marijke. (2016) Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovascular research, 109 (1). pp. 103-114.

Swierczynska, Marta M. and Hall, Michael N.. (2016) mTOR in Metabolic and Endocrine Disorders. In: Molecules to Medicine with mTOR. Translating Critical Pathways into Novel Therapeutic Strategies. London, pp. 347-364.

4 December 2015

Aimi, Fabio and Georgiopoulou, Stavroula and Kalus, Ina and Lehner, Fabienne and Hegglin, Alica and Limani, Përparim and Gomes de Lima, Vinicius and Rüegg, Markus A. and Hall, Michael N. and Lindenblatt, Nicole and Haas, Elvira and Battegay, Edouard J. and Humar, Rok. (2015) Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. Scientific reports, 5. p. 17705.

October 2015

Liko, Dritan and Hall, Michael N.. (2015) mTOR in health and in sickness. Journal of molecular medicine, 93 (10). pp. 1061-1073.

2015

Albert, Verena. The role of hypothalamic mTORC1 and adipose tissue mTORC2 in organismal energetics. 2015, PhD Thesis, University of Basel, Faculty of Science.

Albert, Verena and Cornu, Marion and Hall, Michael N.. (2015) mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. Biochemical and Biophysical Research Communications, Vol. 464, H. 2. S. 480-486.

Albert, Verena and Hall, Michael N.. (2015) Reduced C/EBPβ-LIP translation improves metabolic health. EMBO reports, Vol. 16, H. 8. S. 881-882.

Carr, T. D. and Feehan, R. P. and Hall, M. N. and Rüegg, M. A. and Shantz, L. M.. (2015) Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors. Carcinogenesis, Vol. 36, H. 4. S. 487-497.

Drägert, Katja and Bhattacharya, Indranil and Pellegrini, Giovanni and Seebeck, Petra and Azzi, Abdelhalim and Brown, Steven A. and Georgiopoulou, Stavroula and Held, Ulrike and Blyszczuk, Przemyslaw and Arras, Margarete and Humar, Rok and Hall, Michael N. and Battegay, Edouard and Haas, Elvira. (2015) Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood Pressure. Hypertension, 66 (2). pp. 332-339.

González, A. and Shimobayashi, M. and Eisenberg, T. and Merle, D. A. and Pendl, T. and Hall, M. N. and Moustafa, T.. (2015) TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae. PLoS one, Vol. 10, H. 3 , e0120250.

Hindupur, Sravanth K. and González, Asier and Hall, Michael N.. (2015) The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control. Cold Spring Harbor perspectives in biology, Vol. 7, H. 8. S. 1-21.

Lopez, Rubén J. and Mosca, Barbara and Treves, Susan and Maj, Marcin and Bergamelli, Leda and Calderon, Juan C. and Bentzinger, C. Florian and Romanino, Klaas and Hall, Michael N. and Rüegg, Markus A. and Delbono, Osvaldo and Caputo, Carlo and Zorzato, Francesco. (2015) Raptor ablation in skeletal muscle decreases Cav1.1 expression and affects the function of the excitation-contraction coupling supramolecular complex. Biochemical Journal, 466 (1). pp. 123-135.

Ma, S. and Venkatesh, A. and Langellotto, F. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival. Experimental eye research, Vol. 135. S. 1-13.

Martin, S. K. and Fitter, S. and Dutta, A. K. and Matthews, M. P. and Walkley, C. R. and Hall, M. N. and Ruegg, M. A. and Gronthos, S. and Zannettino, A. C. W.. (2015) The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem cells, Vol. 33, H. 4. S. 1359-1365.

Oliveira, A. P. and Dimopoulos, S. and Busetto, A. G. and Christen, S. and Dechant, R. and Falter, L. and Haghir, C. M. and Jozefczuk, S. and Ludwig, C. and Rudroff, F. and Schulz, J. C. and González, A. and Soulard, A. and Stracka, D. and Aebersold, R. and Buhmann, J. M. and Hall, M. N. and Peter, M. and Sauer, U. and Stelling, J.. (2015) Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptome. Molecular systems biology, Vol. 11, H. 4. S. 802.

Stracka, Daniele. Upstream regulation of yeast TOR complexes. 2015, PhD Thesis, University of Basel, Faculty of Science.

Vanella, Rosario. Yeast-based strategy for identification of 11β-HSD1 inhibitors. 2015, PhD Thesis, University of Basel, Faculty of Science.

Venkatesh, A. and Ma, S. and Le, Y. Z. and Hall, M. N. and Rüegg, M. A. and Punzo, C.. (2015) Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. The Journal of clinical investigation, Vol. 125, H. 4. S. 1446-1458.

2014

Albert, V. and Hall, M. N.. (2014) mTOR signaling in cellular and organismal energetics. Current opinion in cell biology, Vol. 33C. S. 55-66.

Benjamin, D. and Hall, M. N.. (2014) mTORC1: Turning Off Is Just as Important as Turning On. Cell, Vol. 156, H. 4. S. 627-628.

Chen, J. and Tu, X. and Esen, E. and Joeng, K. S. and Lin, C. and Arbeit, J. M. and Rüegg, M. A. and Hall, M. N. and Ma, L. and Long, F.. (2014) WNT7B promotes bone formation in part through mTORC1. PLoS genetics, Vol. 10, H. 1 , e1004145.

Chou, Po-Chien and Oh, Won Jun and Wu, Chang-Chih and Moloughney, Joseph and Rüegg, Markus A. and Hall, Michael N. and Jacinto, Estela and Werlen, Guy. (2014) Mammalian target of rapamycin complex 2 modulates αβTCR processing and surface expression during thymocyte development. Journal of immunology, Vol. 193, H. 3. S. 1162-1170.

Cornu, M. and Oppliger, W. and Albert, V. and Robitaille, A. M. and Trapani, F. and Quagliata, L. and Fuhrer, T. and Sauer, U. and Terracciano, L. and Hall, M. N.. (2014) Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21. Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, H. 32. S. 11592-11599.

Faller, W. J. and Jackson, T. J. and Knight, J. R. P. and Ridgway, R. A. and Jamieson, T. and Karim, S. A. and Jones, C. and Radulescu, S. and Huels, D. J. and Myant, K. B. and Dudek, K. M. and Casey, H. A. and Scopelliti, A. and Cordero, J. B. and Vidal, M. and Pende, M. and Ryazanov, A. G. and Sonenberg, N. and Meyuhas, O. and Hall, M. N. and Bushell, M. and Willis, A. E. and Sansom, O. J.. (2014) mTORC1-mediated translational elongation limits intestinal tumour initiation and growth. Nature, Vol. 517, H. 7535. S. 497-500.

Grahammer, F. and Haenisch, N. and Steinhardt, F. and Sander, L. and Roerden, M. and Arnold, F. and Cordts, T. and Wanner, N. and Reichardt, W. and Kerjaschki, D. and Ruegg, M. A. and Hall, M. N. and Moulin, P. and Busch, H. and Boerries, M. and Walz, G. and Artunc, F. and Huber, T. B.. (2014) mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, H. 27 , E2817-E2826.

Keglowich, Laura Franziska. Airway wall remodeling in asthma : novel mechanisms of human bronchial smooth muscle cells in the induction of angiogenesis. 2014, PhD Thesis, University of Basel, Faculty of Science.

Lebrun-Julien, F. and Bachmann, L. and Norrmén, C. and Trötzmüller, M. and Köfeler, H. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination. Journal of neuroscience, Vol. 34, H. 25. S. 8432-8448.

Norrmén, C. and Figlia, G. and Lebrun-Julien, F. and Pereira, J. A. and Trötzmüller, M. and Köfeler, H. C. and Rantanen, V. and Wessig, C. and van Deijk, A. F. and Smit, A. B. and Verheijen, M. G. and Rüegg, M. A. and Hall, M. N. and Suter, U.. (2014) mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells. Cell reports, Vol. 9, H. 2. S. 646-660.

Shimobayashi, M. and Hall, M. N.. (2014) Making new contacts : the mTOR network in metabolism and signalling crosstalk. Nature reviews. Molecular cell biology, Vol. 15, H. 3. S. 155-162.

Siamer, S. and Guillas, I. and Shimobayashi, M. and Kunz, C. and Hall, M. N. and Barny, M. A.. (2014) Expression of the bacterial type III effector DspA/E in Saccharomyces cerevisiae downregulates the sphingolipid biosynthetic pathway leading to growth-arrest. Journal of biological chemistry, Vol. 289, H. 26. S. 18466-18477.

Stracka, Daniele and Jozefczuk, Szymon and Rudroff, Florian and Sauer, Uwe and Hall, Michael N.. (2014) Nitrogen Source Activates TOR (Target of Rapamycin) Complex 1 via Glutamine and Independently of Gtr/Rag Proteins. Journal of biological chemistry, Vol. 289, H. 36. S. 25010-25020.

Umemura, A. and Park, E. J. and Taniguchi, K. and Lee, J. H. and Shalapour, S. and Valasek, M. A. and Aghajan, M. and Nakagawa, H. and Seki, E. and Hall, M. N. and Karin, M.. (2014) Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell metabolism, Vol. 20, H. 1. S. 133-144.

Zhang, Lianjun and Tschumi, Benjamin O. and Corgnac, Stéphanie and Rüegg, Markus A. and Hall, Michael N. and Mach, Jean-Pierre and Romero, Pedro and Donda, Alena. (2014) Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function. Journal of immunology, Vol. 193, H. 4. S. 1759-1765.

de Cabo, R. and Carmona-Gutierrez, D. and Bernier, M. and Hall, M. N. and Madeo, F.. (2014) The Search for Antiaging Interventions : From Elixirs to Fasting Regimens. Cell, Vol. 157, H. 7. S. 1515-1526.

2013

Benjamin, D. and Hall, M. N.. (2013) TSC on the peroxisome controls mTORC1. Nature Cell Biology, Vol. 15, H. 10. S. 1135-1136.

Bentzinger, C. Florian and Lin, Shuo and Romanino, Klaas and Castets, Perrine and Guridi, Maitea and Summermatter, Serge and Handschin, Christoph and Tintignac, Lionel A. and Hall, Michael N. and Rüegg, Markus A.. (2013) Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal muscle, Vol. 3, H. 1 , 6.

Betz, C. and Hall, M. N.. (2013) Where is mTOR and what is it doing there? Journal of cell biology, Vol. 203, H. 4. S. 563-574.

Betz, C. and Stracka, D. and Prescianotto-Baschong, C. and Frieden, M. and Demaurex, N. and Hall, M. N.. (2013) mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 31. S. 12526-12534.

Bhattacharya, I. and Drägert, K. and Albert, V. and Contassot, E. and Damjanovic, M. and Hagiwara, A. and Zimmerli, L. and Humar, R. and Hall, M. N. and Battegay, E. J. and Haas, E.. (2013) Rictor in Perivascular Adipose Tissue Controls Vascular Function by Regulating Inflammatory Molecule Expression. Arteriosclerosis, thrombosis, and vascular biology, Vol. 33, H. 9. S. 2105-2111.

Blazek, M. and Betz, C. and Reth, M. and Hall, M. N. and Zengerle, R. and Meier, M.. (2013) Proximity Ligation Assay for High Content Profiling of Cell Signaling Pathways on a Microfluidic Chip. Molecular & cellular proteomics, Vol. 12. S. 3898-3907.

Cornu, Marion and Albert, Verena and Hall, Michael N.. (2013) mTOR in aging, metabolism, and cancer. Current opinion in genetics & development, Vol. 23, H. 1 , S. 53–62.

Hall, M. N.. (2013) On mTOR nomenclature. Biochemical Society transactions, Vol. 41, H. 4. S. 8817-8888.

Robitaille, A. M. and Christen, S. and Shimobayashi, M. and Cornu, M. and Fava, L. L. and Moes, S. and Prescianotto-Baschong, C. and Sauer, U. and Jenoe, P. and Hall, M. N.. (2013) Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis. Science, Vol. 339, H. 6125. S. 1320-1323.

Saldivia, M. and Barquilla, A. and Bart, J. M. and Diaz-González, R. and Hall, M. N. and Navarro, M.. (2013) Target of rapamycin (TOR) kinase in Trypanosoma brucei : an extended family. Biochemical Society transactions, Vol. 41, H. 4. S. 934-938.

Sauer, E. and Imseng, S. and Maier, T. and Hall, M. N.. (2013) Conserved sequence motifs and the structure of the mTOR kinase domain. Biochemical Society transactions, Vol. 41, H. 4. S. 889-895.

Schlatter, Ivan. Functional analysis of "MEMO / MHO1", an evolutionary conserved gene, in yeast and mammalian cells. 2013, PhD Thesis, University of Basel, Faculty of Science.

Schultze, Simon Manuel. The role of systemically perturbed PTEN and PKBß/AKT2 signaling in accumulation of hepatic lipids. 2013, PhD Thesis, University of Basel, Faculty of Science.

Shende, Pankaj. Dissecting the roles of mTORC1 and mTORC2 in the mouse heart. 2013, PhD Thesis, University of Basel, Faculty of Science.

Shimobayashi, M. and Oppliger, W. and Moes, S. and Jenö, P. and Hall, M. N.. (2013) TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis. Molecular biology of the cell, Vol. 24, H. 6. S. 870-881.

Shortt, J. and Martin, B. P. and Newbold, A. and Hannan, K. M. and Devlin, J. R. and Baker, A. J. and Ralli, R. and Cullinane, C. and Schmitt, C. A. and Reimann, M. and Hall, M. N. and Wall, M. and Hannan, R. D. and Pearson, R. B. and McArthur, G. A. and Johnstone, R. W.. (2013) Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas. Blood, Vol. 121, H. 15. S. 2964-2974.

Thedieck, K. and Holzwarth, B. and Prentzell, M. T. and Boehlke, C. and Kläsener, K. and Ruf, S. and Sonntag, A. G. and Maerz, L. and Grellscheid, S. N. and Kremmer, E. and Nitschke, R. and Kuehn, E. W. and Jonker, J. W. and Groen, A. K. and Reth, M. and Hall, M. N. and Baumeister, R.. (2013) Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells. Cell, Vol. 154, H. 4. S. 859-874.

Wyder Peters, L. and Molle, K. D. and Thiemeyer, A. and Knopf, A. and Goxe, M. and Guerry, P. and Brodbeck, D. and Colombi, M. and Hall, M. N. and Moroni, C. and Regenass, U.. (2013) An Isogenic Cell Panel Identifies Compounds That Inhibit Proliferation of mTOR-Pathway Addicted Cells by Different Mechanisms. Journal of biomolecular screening, Vol. 19, H. 1. S. 131-144.

2012

Appenzeller-Herzog, Christian and Hall, Michael N.. (2012) Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends in cell biology : TCB, 22 (5). pp. 272-282.

Barquilla, A. and Saldivia, M. and Diaz, R. and Bart, J. -M. and Vidal, I. and Calvo, E. and Hall, M. N. and Navarro, M.. (2012) Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Iss. 36. S. 14399-14404.

Betz, Charles. mTOR complex 2 - akt signaling is physically and functionally at mam. 2012, PhD Thesis, University of Basel, Faculty of Science.

Cardon, C. M. and Beck, T. and Hall, M. N. and Rutter, J.. (2012) PAS kinase promotes cell survival and growth through activation of Rho1. Science signaling, Vol. 5, H. 209 , ra9.

Cremonesi, Alessio. Characterization of the yeast rapamycin-sensitive phosphoproteome. 2012, PhD Thesis, University of Basel, Faculty of Science.

Cybulski, Nadine and Zinzalla, Vittoria and Hall, Michael N.. (2012) Inducible raptor and rictor Knockout Mouse Embryonic Fibroblasts. Methods in molecular biology (Humana Press), 821. S. 267-278.

Durán, R. V. and Hall, M. N.. (2012) Leucyl-tRNA synthetase : double duty in amino acid sensing. Cell research, Vol. 22. S. 1207-1209.

Durán, R. V. and Hall, M. N.. (2012) Regulation of TOR by small GTPases. EMBO reports, Vol. 13, H. 2. S. 121-128.

Durán, R. V. and Mackenzie, E. D. and Boulahbel, H. and Frezza, C. and Heiserich, L. and Tardito, S. and Bussolati, O. and Rocha, S. and Hall, M. N. and Gottlieb, E.. (2012) HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene, Vol. 31. S. 1-8.

Durán, R. V. and Oppliger, W. and Robitaille, A. M. and Heiserich, L. and Skendaj, R. and Gottlieb, E. and Hall, M. N.. (2012) Glutaminolysis activates Rag-mTORC1 signaling. Molecular cell, Vol. 47, H. 3. S. 349-358.

Durán, Raúl V. and Hall, Michael N.. (2012) Glutaminolysis feeds mTORC1. Cell cycle, Vol. 11, H. 22. S. 4107-4108.

Hagiwara, Asami and Cornu, Marion and Cybulski, Nadine and Polak, Pazit and Betz, Charles and Trapani, Francesca and Terracciano, Luigi and Heim, Markus H. and Rüegg, Markus A. and Hall, Michael N.. (2012) Hepatic mTORC2 activates glycolysis and lipogenesis through akt, glucokinase, and SREBP1c. Cell metabolism, Vol. 15, H. 5. S. 725-738.

Liu, Q. and Ren, T. and Fresques, T. and Oppliger, W. and Niles, B. J. and Hur, W. and Sabatini, D. M. and Hall, M. N. and Powers, T. and Gray, N. S.. (2012) Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS chemical biology, Vol. 7, H. 6. S. 982-987.

Robitaille, A. M. and Hall, M. N.. (2012) Ramping up mitosis : an AMPKα2-regulated signaling network promotes mitotic progression. Molecular cell, Vol. 45, H. 1. S. 8-9.

Robitaille, Aaron M.. Quantitative phosphoproteomics reveal that mTOR regulates cell growth and proliferation by phosphorylating a functionally diverse set of substrates. 2012, PhD Thesis, University of Basel, Faculty of Science.

2011

Benjamin, Don and Colombi, Marco and Moroni, Christoph and Hall, Michael N.. (2011) Rapamycin passes the torch: a new generation of mTOR inhibitors. Nature reviews. Drug discovery, Vol. 10, H. 11. S. 868-880.

Chan, J. C. and Hannan, K. M. and Riddell, K. and Ng, P. Y. and Peck, A. and Lee, R. S. and Hung, S. and Astle, M. V. and Bywater, M. and Wall, M. and Poortinga, G. and Jastrzbeski, K. and Sheppard, K. E. and Hemmings, B. A. and Hall, M. N. and Johnstone, R. W. and McArthur, G. A. and Hannan, R. D. and Pearson, R. B.. (2011) AKT is a critical regulator of rRNA synthesis and cooperates with c-MYC to control ribosome biogenesis in cancer. Science signaling, Vol. 4, H. 188 , ra56.

Colombi, M. and Molle, K. D. and Benjamin, D. and Rattenbacher-Kiser, K. and Schaefer, C. and Betz, C. and Thiemeyer, A. and Regenass, U. and Hall, M. N. and Moroni, C.. (2011) Genome-wide shRNA screen reveals increased mitochondrial dependence upon mTORC2 addiction. Oncogene, Vol. 30, H. 13. S. 1551-1565.

Dazert, E. and Hall, M. N.. (2011) mTOR signaling in disease. Current opinion in cell biology, Vol. 23, H. 6. S. 744-755.

Godel, M. and Hartleben, B. and Herbach, N. and Liu, S. and Zschiedrich, S. and Lu, S. and Debreczeni-Mor, A. and Lindenmeyer, M. T. and Rastaldi, M. -P. and Hartleben, G. and Wiech, T. and Fornoni, A. and Nelson, R. G. and Kretzler, M. and Wanke, R. and Pavenstadt, H. and Kerjaschki, D. and Cohen, C. D. and Hall, M. N. and Ruegg, M. A. and Inoki, K. and Walz, G. and Huber, T. B.. (2011) Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. The Journal of clinical investigation, Vol. 121, H. 6. S. 2197-2209.

Hall, M. N.. (2011) Growth grows up COCB themed issue on cell division, growth, and death. Current opinion in cell biology, Vol. 23, H. 6. S. 705-706.

Hall, M. N.. (2011) The history and perspectives of TOR research. Jikken Igaku (Experimental Medicine), Vol. 29. S. 862-864.

Inoki, K. and Mori, H. and Wang, J. and Suzuki, T. and Hong, S. and Yoshida, S. and Blattner, S. M. and Ikenoue, T. and Ruegg, M. A. and Hall, M. N. and Kwiatkowski, D. J. and Rastaldi, M. P. and Huber, T. B. and Kretzler, M. and Holzman, L. B. and Wiggins, R. C. and Guan, K. -L.. (2011) mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. The Journal of clinical investigation, Vol. 121, H. 6. S. 2181-2196.

Loewith, R. and Hall, M. N.. (2011) Target of Rapamycin (TOR) in nutrient signaling and growth control. Genetics, Vol. 189, H. 4. S. 1177-1201.

Schmitz-Rohmer, Debora. Mammalian NDR kinases : tumor suppressors with essential functions in embryonic development. 2011, PhD Thesis, University of Basel, Faculty of Science.

Shende, P. and Plaisance, I. and Morandi, C. and Pellieux, C. and Berthonneche, C. and Zorzato, F. and Krishnan, J. and Lerch, R. and Hall, M. N. and Ruegg, M. A. and Pedrazzini, T. and Brink, M.. (2011) Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation, 123 (10). pp. 1073-1082.

Zinzalla, V. and Stracka, D. and Oppliger, W. and Hall, M. N.. (2011) Activation of mTORC2 by Association with the Ribosome. Cell, Vol. 144, H. 5. S. 757-768.

2010

Tamanoi, F. and Hall, M. N., eds. (2010) Structure, Function and Regulation of TOR Complexes from Yeasts to Mammals. The enzymes, Vol. 27-28. Amsterdam.

Blagosklonny, Mikhail V. and Campisi, Judy and Sinclair, David A. and Bartke, Andrzej and Blasco, Maria A. and Bonner, William M. and Bohr, Vilhelm A. and Brosh, Robert M. and Brunet, Anne and Depinho, Ronald A. and Donehower, Lawrence A. and Finch, Caleb E. and Finkel, Toren and Gorospe, Myriam and Gudkov, Andrei V. and Hall, Michael N. and Hekimi, Siegfried and Helfand, Stephen L. and Karlseder, Jan and Kenyon, Cynthia and Kroemer, Guido and Longo, Valter and Nussenzweig, Andre and Osiewacz, Heinz D. and Peeper, Daniel S. and Rando, Thomas A. and Rudolph, K. Lenhard and Sassone-Corsi, Paolo and Serrano, Manuel and Sharpless, Norman E. and Skulachev, Vladimir P. and Tilly, Jonathan L. and Tower, John and Verdin, Eric and Vijg, Jan. (2010) Impact papers on aging in 2009. Aging, Vol. 2, H. 3. S. 111-121.

Cornu, M. and Hall, M. N.. (2010) mTORC1 and mTORC2 in energy homeostasis. In: Structure, function and regulation of TOR complexes from yeasts to mammals, Part B. Amsterdam, S. 263-278.

Cybulski, Nadine. New insights into the "in vivo" and "in vitro" functions of mammalian TOR complex 2. 2010, PhD Thesis, University of Basel, Faculty of Science.

Michels, A. A. and Robitaille, A. M. and Buczynski-Ruchonnet, D. and Hodroj, W. and Reina, J. H. and Hall, M. N. and Hernandez, N.. (2010) mTORC1 directly phosphorylates and regulates human MAF1. Molecular and cellular biology, Vol. 30, H. 15. S. 3749-3757.

Soulard, A. and Cremonesi, A. and Moes, S. and Schutz, F. and Jeno, P. and Hall, M. N.. (2010) The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates. Molecular biology of the cell, Vol. 21, H. 19. S. 3475-3486.

Thedieck, K. and Hall, M. N.. (2010) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, S. 2285-2293.

Zinzalla, V. and Sturgill, T. W. and Hall, . (2010) TOR complexes : composition, structure and phosphorylation. In: Structure, function and regulation of TOR complexes from yeasts to mammals, Part A. Amsterdam, S. 1-20.

2009

Blagosklonny, Mikhail V. and Hall, Michael N.. (2009) Growth and aging : a common molecular mechanism. Aging, Vol. 1, H. 4. S. 357-362.

Cohen, A. and Hall, M. N.. (2009) An amino acid shuffle activates mTORC1. Cell, Vol. 136, H. 3. S. 399-400.

Cybulski, N. and Hall, M. N.. (2009) TOR complex 2 : a signaling pathway of its own. Trends in biochemical sciences, Vol. 34, H. 12. S. 620-627.

Cybulski, N. and Polak, P. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2009) mTOR complex 2 in adipose tissue negatively controls whole-body growth. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, H. 24. S. 9902-9907.

Fan, Xiucheng. Investigation of quantitative and qualitative MtDNA alteration in breast cancer. 2009, PhD Thesis, University of Basel, Faculty of Science.

Kalender, Adem. Regulation of the mTOR/S6K pathway by cellular energy. 2009, PhD Thesis, University of Basel, Faculty of Science.

Patursky-Polischuk, I. and Stolovich-Rain, M. and Hausner-Hanochi, M. and Kasir, J. and Cybulski, N. and Avruch, J. and Ruegg, M. A. and Hall, M. N. and Meyuhas, O.. (2009) The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner. Molecular and cellular biology, Vol. 29, H. 3. S. 640-649.

Polak, P. and Hall, M. N.. (2009) mTOR and the control of whole body metabolism. Current opinion in cell biology, Vol. 21, H. 2. S. 209-218.

Soulard, A. and Cohen, A. and Hall, M. N.. (2009) TOR signaling in invertebrates. Current opinion in cell biology, Vol. 21, H. 6. S. 825-836.

Sturgill, T. W. and Hall, M. N.. (2009) Activating Mutations in TOR Are in Similar Structures As Oncogenic Mutations in PI3KCalpha. ACS chemical biology, Vol. 4, no. 12. S. 999-1015.

2008

Bentzinger, C. F. and Romanino, K. and Cloetta, D. and Lin, S. and Mascarenhas, J. B. and Oliveri, F. and Xia, J. and Casanova, E. and Costa, C. F. and Brink, M. and Zorzato, F. and Hall, M. N. and Ruegg, M. A.. (2008) Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metabolism, Vol. 8, H. 5. S. 411-424.

Christen, Verena. Interferon alpha signaling in viral hepatitis. 2008, PhD Thesis, University of Basel, Faculty of Science.

Gander, S. and Bonenfant, D. and Altermatt, P. and Martin, D. E. and Hauri, S. and Moes, S. and Hall, M. N. and Jenoe, P.. (2008) Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. Rapid communications in mass spectrometry, Vol. 22, H. 23. S. 3743-3753.

Hall, M. N.. (2008) mTOR - what does it do? Transplantation proceedings, Vol. 40, no. 10 , S5-S8.

Jiang, H. and Schiffer, E. and Song, Z. and Wang, J. and Zurbig, P. and Thedieck, K. and Moes, S. and Bantel, H. and Saal, N. and Jantos, J. and Brecht, M. and Jeno, P. and Hall, M. N. and Hager, K. and Manns, M. P. and Hecker, H. and Ganser, A. and Dohner, K. and Bartke, A. and Meissner, C. and Mischak, H. and Ju, Z. and Rudolph, K. L.. (2008) Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, H. 32. S. 11299-11304.

Necker, Judith. Hereditary colorectal cancer : assessment of genotype-phenotype correlations and analysis of rare susceptibility genes in familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC). 2008, PhD Thesis, University of Basel, Faculty of Science.

Polak, P. and Cybulski, N. and Feige, J. N. and Auwerx, J. and Ruegg, M. A. and Hall, M. N.. (2008) Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration. Cell Metabolism, Vol. 8, H. 5. S. 399-410.

Polak, Pazit. Regulation of adipogenesis and adipose maintenance by the mammalian TOR complex 1. 2008, PhD Thesis, University of Basel, Faculty of Science.

Robitaille, A. M. and Hall, M. N.. (2008) mTor. UCSD Nature Molecular Pages, 2008, A000094.

Sturgill, T. W. and Cohen, A. and Diefenbacher, M. and Trautwein, M. and Martin, D. E. and Hall, M. N.. (2008) TOR1 and TOR2 have distinct locations in live cells. Eukaryotic Cell, Vol. 7, H. 10. S. 1819-1830.

Zinzalla, V. and Hall, M. N.. (2008) Signal transduction : linking nutrients to growth. Nature, Vol. 454. S. 287-288.

2007

Anastasiou, Dimitrios. Identification of novel mechanisms regulating the NAD+ -dependent deacetylase SIRT1. 2007, PhD Thesis, University of Basel, Faculty of Science.

Emter, Roger. Functional dissection of the C-terminal part of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator alpha (PGC-1[alpha]). 2007, PhD Thesis, University of Basel, Faculty of Science.

Gander, Stefan. Functional analysis of the "Saccharomyces cerevisiae" Npr1 protein kinase. 2007, PhD Thesis, University of Basel, Faculty of Science.

Li, Weimin and Petrimpol, Marco and Molle, Klaus D. and Hall, Michael N. and Battegay, Edouard J. and Humar, Rok. (2007) Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2. Circulation research, Vol. 100, H. 1. S. 79-87.

Soulard, A. and Hall, M. N.. (2007) SnapShot : mTOR signaling. Cell, Vol. 129, H. 2. S. 434.

Sturgill, T. W. and Hall, M. N.. (2007) Holding back TOR advances mitosis. Nature Cell Biology, Vol. 9, H. 11. S. 1221-1222.

Thedieck, K. and Polak, P. and Kim, M. L. and Molle, K. D. and Cohen, A. and Jeno, P. and Arrieumerlou, C. and Hall, M. N.. (2007) PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS one, Vol. 2, H. 11 , e1217.

Urban, J. and Soulard, A. and Huber, A. and Lippman, S. and Mukhopadhyay, D. and Deloche, O. and Wanke, V. and Anrather, D. and Ammerer, G. and Riezman, H. and Broach, J. R. and De Virgilio, C. and Hall, M. N. and Loewith, R.. (2007) Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. Molecular cell, Vol. 26, H. 5. S. 663-674.

2006

Linder, P. and Shore, D. and Hall, M. N., eds. (2006) Landmark papers in yeast biology. New York.

Di Cara, Alessandro. Disruption of ribosome biogenesis triggers a p21/p53-mediated cell cycle checkpoint. 2006, PhD Thesis, University of Basel, Faculty of Science.

Honma, Yoshimi and Kitamura, Aiko and Shioda, Ryo and Maruyama, Hironori and Ozaki, Kanako and Oda, Yoko and Mini, Thierry and Jenö, Paul and Maki, Yasushi and Yonezawa, Kazuyoshi and Hurt, Ed and Ueno, Masaru and Uritani, Masahiro and Hall, Michael N. and Ushimaru, Takashi. (2006) TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. The EMBO journal, Vol. 25, H. 16. S. 3832-3842.

Martin, D. E. and Powers, T. and Hall, M. N.. (2006) Regulation of ribosome biogenesis : where is TOR? Cell Metabolism, Vol. 4, H. 4. S. 259-260.

Molle, Klaus-Dieter. Regulation of the mammalian target of rapamycin complex 2 (mTORC2). 2006, PhD Thesis, University of Basel, Faculty of Science.

Mulet, J. M. and Martin, D. E. and Loewith, R. and Hall, M. N.. (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. Journal of Biological Chemistry, Vol. 281, H. 44. S. 33000-33007.

Polak, P. and Hall, M. N.. (2006) mTORC2 Caught in a SINful Akt. Developmental cell, Vol. 11, H. 4. S. 433-434.

Shioda, Ryo. Functional analysis of TOR complex 2 and its control of sphingolipid biosynthesis in "Saccharomyces cerevisiae". 2006, PhD Thesis, University of Basel, Faculty of Science.

Wahl, Patricia R. and Serra, Andreas L. and Le Hir, Michel and Molle, Klaus D. and Hall, Michael N. and Wüthrich, Rudolf P.. (2006) Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Nephrology, dialysis, transplantation, Vol. 21, H. 3. S. 598-604.

Wullschleger, S. and Loewith, R. and Hall, M. N.. (2006) TOR signaling in growth and metabolism. Cell, Vol. 124, H. 3. S. 471-484.

2005

Dames, S. A. and Mulet, J. M. and Rathgeb-Szabo, K. and Hall, M. N. and Grzesiek, S.. (2005) The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. Journal of biological chemistry, Vol. 280, H. 21. S. 20558-20564.

Kamada, Y. and Fujioka, Y. and Suzuki, N. N. and Inagaki, F. and Wullschleger, S. and Loewith, R. and Hall, M. N. and Ohsumi, Y.. (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Molecular and Cellular Biology, Vol. 25, H. 16. S. 7239-7248.

Li, Weimin. Responses to hypoxia via mTOR : role in endothelial cell proliferation and HIF-1[alpha] stabilization. 2005, PhD Thesis, University of Basel, Faculty of Science.

Martin, D. E. and Hall, M. N.. (2005) The expanding TOR signaling network. Current opinion in cell biology, Vol. 17, H. 2. S. 158-166.

Meier, Karsten D.. Mechanisms of sphingolipid functions during heat stress in "Saccharomyces cerevisiae". 2005, PhD Thesis, University of Basel, Faculty of Science.

Schmidlin-Stalder, Martin. Regulation of mRNA stability via BRF1 and other AU-binding proteins. 2005, PhD Thesis, University of Basel, Faculty of Science.

Wullschleger, S. and Loewith, R. and Oppliger, W. and Hall, M. N.. (2005) Molecular organization of target of rapamycin complex 2. Journal of Biological Chemistry, Vol. 280, H. 35. S. 30697-30704.

Zamurovic, Natasa. Transcriptional program of osteoblast differentiation : coordinated activation of Notch, Wnt, and TGF-[beta] signaling pathways in MC3T3 cell line. 2005, PhD Thesis, University of Basel, Faculty of Science.

2004

Hall, M. N. and Raff, M. and Thomas, G., eds. (2004) Cell growth : control of cell size. Cold Spring Harbor monograph series, 42. New York.

Thomas, George and Sabatini, David M. and Hall, Michael N., eds. (2004) TOR : target of rapamycin. Current topics in microbiology and immunology, 279. Heidelberg.

Audhya, Anjon and Loewith, Robbie and Parsons, Ainslie B. and Gao, Lu and Tabuchi, Mitsuaki and Zhou, Huilin and Boone, Charles and Hall, Michael N. and Emr, Scott D.. (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. The EMBO journal, Vol. 23, H. 19. S. 3747-3757.

Bucior, Iwona. Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition and adhesion. 2004, PhD Thesis, University of Basel, Faculty of Science.

Burri, L. and Vascotto, K. and Fredersdorf, S. and Tiedt, R. and Hall, M. N. and Lithgow, T.. (2004) Zim17 : a novel zinc finger protein essential for protein import into mitochondria. Journal of Biological Chemistry, Vol. 279, H. 48. S. 50243-50249.

Crespo, J. L. and Helliwell, S. B. and Wiederkehr, C. and Demougin, P. and Fowler, B. and Primig, M. and Hall, M. N.. (2004) NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. Journal of biological chemistry, Vol. 279, H. 36. S. 37512-37517.

Jacinto, E. and Loewith, R. and Schmidt, A. and Lin, S. and Ruegg, M. A. and Hall, A. and Hall, M. N.. (2004) Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nature Cell Biology, Vol. 6, H. 11. S. 1122-1128.

Loewith, R. and Hall, M. N.. (2004) TOR signaling in yeast : temporal and spatial control of cell growth. In: Cell growth. New York, S. 139-166.

Lorberg, A. and Hall, M. N.. (2004) TOR - the first 10 years. Current topics in microbiology and immunology, 279. S. 1-18.

Martin, D. E. and Demougin, P. and Hall, M. N. and Bellis, M.. (2004) Rank difference analysis of microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data. BMC bioinformatics, Vol. 5 , 148.

Martin, D. E. and Soulard, A. and Hall, M. N.. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell, Vol. 119, H. 7. S. 969-979.

Morales-Johansson, H. and Jenoe, P. and Cooke, F. T. and Hall, M. N.. (2004) Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4. Journal of biological chemistry, Vol. 279 , no. 38. S. 39604-39610.

Morales-Johansson, Helena. Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae". 2004, PhD Thesis, University of Basel, Faculty of Science.

Schmelzle, T. and Beck, T. and Martin, D. E. and Hall, M. N.. (2004) Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast. Molecular and cellular biology, Vol. 24, H. 1. S. 338-351.

Schmelzle, T. and Crespo, J. L. and Hall, M. N.. (2004) Translational control by amino acids and energy. In: Handbook of cell signaling, Vol. 3. San Diego, California, S. 299-303.

Schmidt, Karsten. Analysis of the structure and function of protein phosphatase 2A. 2004, PhD Thesis, University of Basel, Faculty of Science.

Schreiber, Sylvia Nicole. The transcriptional coactivator PGC-1[alpha] as a modulator of ERR[alpha] and GR signaling : function in mitochondrial biogenesis. 2004, PhD Thesis, University of Basel, Faculty of Science.

Um, Sung Hee. The role of S6K1 in development and maintenance of nutrient homeostasis. 2004, PhD Thesis, University of Basel, Faculty of Science.

Wullschleger, Stephan. Characterization of TOR complex 2 (TORC2) in "Saccharomyces cerevisiae". 2004, PhD Thesis, University of Basel, Faculty of Science.

2003

Bonenfant, D. and Schmelzle, T. and Jacinto, E. and Crespo, J. L. and Mini, T. and Hall, M. N. and Jenoe, P.. (2003) Quantitation of changes in protein phosphorylation : a simple method based on stable isotope labeling and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 3. S. 880-885.

Jacinto, E. and Hall, M. N.. (2003) Tor signalling in bugs, brain and brawn. Nature reviews. Molecular cell biology, Vol. 4, H. 2. S. 117-126.

2002

Crespo, J. L. and Hall, M. N.. (2002) Elucidating TOR signaling and rapamycin action : lessons from Saccharomyces cerevisiae. Microbiology and molecular biology reviews, Vol. 66, H. 4. S. 579-591.

Crespo, J. L. and Powers, T. and Fowler, B. and Hall, M. N.. (2002) The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine. Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, H. 10. S. 6784-6789.

Desrivieres, S. and Cooke, F. T. and Morales-Johansson, H. and Parker, P. J. and Hall, M. N.. (2002) Calmodulin controls organization of the actin cytoskeleton via regulation of phosphatidylinositol (4,5)-bisphosphate synthesis in Saccharomyces cerevisiae. The Biochemical Journal, Vol. 366, Pt. 3. S. 945-951.

Loewith, R. and Jacinto, E. and Wullschleger, S. and Lorberg, A. and Crespo, J. L. and Bonenfant, D. and Oppliger, W. and Jenoe, P. and Hall, M. N.. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Molecular cell, Vol. 10, H. 3. S. 457-468.

Schmelzle, T. and Helliwell, S. B. and Hall, M. N.. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Molecular and Cellular Biology, Vol. 22, H. 5. S. 1329-1339.

Schmidt, A. and Schmelzle, T. and Hall, M. N.. (2002) The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae. Molecular microbiology, Vol. 45, H. 5. S. 1433-1441.

2001

Beck, T. and Delley, P. A. and Hall, M. N.. (2001) Control of the actin cytoskeleton by extracellular signals. In: Molecular interactions of actin, Vol. 1: Actin structure and actin-binding proteins. Heidelberg, S. 231-262.

Crespo, J. L. and Daicho, K. and Ushimaru, T. and Hall, M. N.. (2001) The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae. Journal of biological chemistry, Vol. 276 , no. 37. S. 34441-34444.

Friant, S. and Lombardi, R. and Schmelzle, T. and Hall, M. N. and Riezman, H.. (2001) Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. The EMBO journal, Vol. 20, H. 23. S. 6783-6792.

Hall, M. N. and Sabatini, D. M.. (2001) TOR and Control of Cell Growth. In: Cahiers de la Fondation des Treilles, 13. Paris, S. 62-82.

Jacinto, E. and Guo, B. and Arndt, K. T. and Schmelzle, T. and Hall, M. N.. (2001) TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Molecular cell, Vol. 8, H. 5. S. 1017-1026.

Lombardi, Ruben. Molecular dissection of the internalization step of endocytosis in "Saccharomyces cerevisiae" : Rvs167p and binding partners. 2001, PhD Thesis, University of Basel, Faculty of Science.

2000

Brachat, A. and Liebundguth, N. and Rebischung, C. and Lemire, S. and Scharer, F. and Hoepfner, D. and Demchyshyn, V. and Howald, I. and Dusterhoft, A. and Mostl, D. and Pohlmann, R. and Kotter, P. and Hall, M. N. and Wach, A. and Philippsen, P.. (2000) Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Yeast, Vol. 16, H. 3. S. 241-253.

Cosentino, G. P. and Schmelzle, T. and Haghighat, A. and Helliwell, S. B. and Hall, M. N. and Sonenberg, N.. (2000) Eap1p, a novel eukaryotic translation initiation factor 4E-associated protein in Saccharomyces cerevisiae. Molecular and Cellular Biology, Vol. 20, H. 13. S. 4604-4613.

Kunz, J. and Loeschmann, A. and Deuter-Reinhard, M. and Hall, M. N.. (2000) FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast. Molecular microbiology, Vol. 37, H. 6. S. 1480-1493.

Kunz, J. and Schneider, U. and Howald, I. and Schmidt, A. and Hall, M. N.. (2000) HEAT repeats mediate plasma membrane localization of Tor2p in yeast. Journal of Biological Chemistry, Vol. 275, H. 47. S. 37011-37020.

Schmelzle, T. and Hall, M. N.. (2000) TOR, a central controller of cell growth. Cell, Vol. 103, H. 2. S. 253-262.

1999

Beck, T. and Hall, M. N.. (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature, Vol. 402. S. 689-692.

Beck, T. and Schmidt, A. and Hall, M. N.. (1999) Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast. The Journal of cell biology, Vol. 146, H. 6. S. 1227-1238.

Danaie, P. and Altmann, M. and Hall, M. N. and Trachsel, H. and Helliwell, S. B.. (1999) CLN3 expression is sufficient to restore G1-to-S-phase progression in Saccharomyces cerevisiae mutants defective in translation initiation factor eIF4E. The Biochemical Journal, Vol. 340, Pt. 1. S. 135-141.

Delley, P. A. and Hall, M. N.. (1999) Cell wall stress depolarizes cell growth via hyperactivation of RHO1. The Journal of cell biology, Vol. 147, H. 1. S. 163-174.

Inagaki, M. and Schmelzle, T. and Yamaguchi, K. and Irie, K. and Hall, M. N. and Matsumoto, K.. (1999) PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast. Molecular and Cellular Biology, Vol. 19, H. 12. S. 8344-8352.

1998

Bickle, M. and Delley, P. A. and Schmidt, A. and Hall, M. N.. (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. The EMBO journal, Vol. 17, H. 8. S. 2235-2245.

Cooke, F. T. and Dove, S. K. and McEwen, R. K. and Painter, G. and Holmes, A. B. and Hall, M. N. and Michell, R. H. and Parker, P. J.. (1998) The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Current biology, Vol. 8, H. 22. S. 1219-1222.

Desrivieres, S. and Cooke, F. T. and Parker, P. J. and Hall, M. N.. (1998) MSS4, a phosphatidylinositol-4-phosphate 5-kinase required for organization of the actin cytoskeleton in Saccharomyces cerevisiae. Journal of Biological Chemistry, Vol. 273, H. 25. S. 15787-15793.

Helliwell, S. B. and Howald, I. and Barbet, N. and Hall, M. N.. (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics, Vol. 148, No. 1. S. 99-112.

Helliwell, S. B. and Schmidt, A. and Ohya, Y. and Hall, M. N.. (1998) The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Current biology, Vol. 8, H. 22. S. 1211-1214.

Schmidt, A. and Beck, T. and Koller, A. and Kunz, J. and Hall, M. N.. (1998) The TOR nutrient signalling pathway phosphorylates NPR1 and inhibits turnover of the tryptophan permease. The EMBO journal, Vol. 17, H. 23. S. 6924-6931.

Schmidt, A. and Hall, M. N.. (1998) Signaling to the actin cytoskeleton. Annual review of cell and developmental biology, Vol. 14. S. 305-338.

1997

Schmidt, A. and Bickle, M. and Beck, T. and Hall, M. N.. (1997) The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Cell, Vol. 88, H. 4. S. 531-542.

Thomas, G. and Hall, M. N.. (1997) TOR signalling and control of cell growth. Current opinion in cell biology, Vol. 9, H. 6. S. 782-787.

1996

Barbet, N. C. and Schneider, U. and Helliwell, S. B. and Stansfield, I. and Tuite, M. F. and Hall, M. N.. (1996) TOR controls translation initiation and early G1 progression in yeast. Molecular biology of the cell, Vol. 7, H. 1. S. 25-42.

Beretta, L. and Gingras, A. C. and Svitkin, Y. V. and Hall, M. N. and Sonenberg, N.. (1996) Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. The EMBO journal, Vol. 15, H. 3. S. 658-664.

Hall, M. N.. (1996) Drug discovery : rational serendipity. Trends in biochemical sciences, Vol. 21. S. 322-323.

Hall, M. N.. (1996) The TOR signalling pathway and growth control in yeast. Biochemical Society transactions, Vol. 24, H. 1. S. 234-239.

Hall, M. N.. (1996) Yeast cloning book cloning. Trends in cell biology, Vol. 6. S. 80.

Koller, A. and Heitman, J. and Hall, M. N.. (1996) Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. Genetics, Vol. 144, No. 3. S. 957-966.

Schmidt, A. and Kunz, J. and Hall, M. N.. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, H. 24. S. 13780-13785.

1994

Garcia-Bustos, J. F. and Marini, F. and Stevenson, I. and Frei, C. and Hall, M. N.. (1994) PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. The EMBO journal, Vol. 13, H. 10. S. 2352-2361.

Hall, M. N.. (1994) Cytosplasm-to-nucleus signaling in yeast: use of immunosuppressive drugs as probes. In: Trafic des Protéines chez les Microorganismes. Paris, S. 55-57.

Helliwell, S. B. and Wagner, P. and Kunz, J. and Deuter-Reinhard, M. and Henriquez, R. and Hall, M. N.. (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Molecular biology of the cell, Vol. 5, H. 1. S. 105-118.

Hottiger, T. and De Virgilio, C. and Hall, M. N. and Boller, T. and Wiemken, A.. (1994) The role of trehalose synthesis for the acquisition of thermotolerance in yeast : II. Physiological concentrations of trehalose increase the thermal stability of proteins in vitro. European journal of biochemistry, Vol. 219, H. 1-2. S. 187-193.

Schmidt, A. and Hall, M. N. and Koller, A.. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Molecular and Cellular Biology, Vol. 14, H. 10. S. 6597-6606.

1993

Hall, M. N. and Linder, P. and Hall, M. N., eds. (1993) The early days of yeast genetics. New York.

Heitman, J. and Koller, A. and Cardenas, M. E. and Hall, M. N.. (1993) Identification of immunosuppressive drug targets in yeast. Methods, Vol. 5, no. 2. S. 176-187.

Heitman, J. and Koller, A. and Kunz, J. and Henriquez, R. and Schmidt, A. and Movva, N. R. and Hall, M. N.. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Molecular and cellular biology, Vol. 13, H. 8. S. 5010-5019.

Kunz, J. and Hall, M. N.. (1993) Cyclosporin A, FK506 and rapamycin : more than just immunosuppression. Trends in biochemical sciences, Vol. 18, H. 9. S. 334-348.

Kunz, J. and Henriquez, R. and Schneider, U. and Deuter-Reinhard, M. and Movva, N. R. and Hall, M. N.. (1993) Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell, Vol. 73, H. 3. S. 585-596.

Wagner, P. and Hall, M. N.. (1993) Nuclear protein transport is functionally conserved between yeast and higher eukaryotes. FEBS letters, Vol. 321, H. 2/3. S. 261-266.

1992

Davis, E. S. and Becker, A. and Heitman, J. and Hall, M. N. and Brennan, M. B.. (1992) A yeast cyclophilin gene essential for lactate metabolism at high temperature. Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, H. 23. S. 11169-11173.

Heitman, J. and Movva, N. R. and Hall, M. N.. (1992) Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. The New Biologist, Vol. 4, no. 5. S. 448-460.

Tinland, B. and Koukolíková-Nicola, Z. and Hall, M. N. and Hohn, B.. (1992) The T-DNA-linked VirD2 protein contains two distinct functional nuclear localization signals. Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, H. 16. S. 7442-7446.

1991

Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1991) Nuclear protein localization. Biochimica et biophysica acta, Vol. 1071, H. 1. S. 83-101.

Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Nuclear import substrates compete for a limited number of binding sites : evidence for different classes of yeast nuclear import receptors. Journal of biological chemistry, Vol. 266 , no. 33. S. 22303-22306.

Garcia-Bustos, J. F. and Wagner, P. and Hall, M. N.. (1991) Yeast cell-free nuclear protein import requires ATP hydrolysis. Experimental cell research, Vol. 192, H. 1. S. 213-219.

Heitman, J. and Movva, N. R. and Hall, M. N.. (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science, Vol. 253, no. 5022. S. 905-909.

Heitman, J. and Movva, N. R. and Hiestand, P. C. and Hall, M. N.. (1991) FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, H. 5. S. 1948-1952.

Tinland, B. and Hall, M. N. and Hohn, B.. (1991) Mechanism of T-DNA transfer. In: Proceedings of the 5th International Symposium on the molecular genetics of plant-microbe interactions, Interlaken, Switzerland, September 9-14, 1990. Dordrecht, S. 79-84.

1990

Hall, M. N. and Craik, C. and Hiraoka, Y.. (1990) Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, H. 18. S. 6954-6958.

Wagner, P. and Kunz, J. and Koller, A. and Hall, M. N.. (1990) Active transport of proteins into the nucleus. FEBS letters, Vol. 275, H. 1/2. S. 1-5.

1988

Hall, M. N. and Fried, S. R.. (1988) Is nuclear protein localization receptor-mediated? In: Molecular Biology of Intracellular Protein Sorting and Organelle Assembly. New York, S. 187-192.

Silver, P. A. and Hall, M. N.. (1988) Transport of proteins into the nucleus. In: Protein transfer and organelle biogenesis. San Diego, Calif., S. 749-769.

1987

Benson, S. A. and Hall, M. N. and Rasmussen, B. A.. (1987) Signal sequence mutations that alter coupling of secretion and translation of an Escherichia coli outer membrane protein. Journal of bacteriology, Vol. 169, H. 10. S. 4686-4691.

Hall, M. N. and Johnson, A. D.. (1987) Homeo domain of the yeast repressor alpha 2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science, Vol. 237, no. 4818. S. 1007-1012.

1986

Garcia-Bustos, J. and Heitman, J. and Hall, M. N.. (1986) Nuclear protein localization signals in yeast. In: Yeast cell biology (UCLA-Symposia on molecular and cellular biology, N.S. Vol. 33). Alan R. Liss, Inc., S. 421-425.

Hall, M. N.. (1986) Considerations on the mechanism of nuclear protein localization in yeast. In: Nucleocytoplasmic transport. Heidelberg, S. 247-252.

1985

Benson, S. A. and Hall, M. N. and Silhavy, T. J.. (1985) Genetic analysis of protein export in Escherichia coli K12. Annual Review of Biochemistry, Vol. 54. S. 101-134.

Hall, M. N.. (1985) Studies on the mechanism of nuclear protein localization in yeast. In: Protein transport and secretion. New York, S. 196-200.

Silhavy, T. J. and Benson, S. A. and Hall, M. N.. (1985) A mechanism to couple transport and export. In: Microbiology - 1985. Washington, S. 454-458.

1984

Berman, M. L. and Jackson, D. E. and Fowler, A. and Zabin, I. and Christensen, L. and Fiil, N. P. and Hall, M. N.. (1984) Gene fusion techniques: Cloning vectors for manipulating IacZ gene fusions. Gene analysis techniques, Vol. 1, H. 3. S. 43-51.

Hall, M. N. and Hereford, L. and Herskowitz, I.. (1984) Targeting of E. coli beta-galactosidase to the nucleus in yeast. Cell, Vol. 36, H. 4. S. 1057-1065.

1983

Hall, M. N. and Gabay, J. and Schwartz, M.. (1983) Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli. The EMBO journal, Vol. 2, H. 1. S. 15-19.

Taylor, R. K. and Hall, M. N. and Silhavy, T. J.. (1983) Isolation and characterization of mutations altering expression of the major outer membrane porin proteins using the local anaesthetic procaine. Journal of molecular biology, Vol. 166, H. 3. S. 273-282.

1982

Benson, S. and Emr, S. and Hall, M. and Silhavy, T. and Sodergren, E.. (1982) Genetic approaches to study export of LamB to the outer membrane. Annales de Microbiologie, Vol. 133a, H. 1. S. 115-122.

Hall, M. N. and Gabay, J. and Debarbouille, M. and Schwartz, M.. (1982) A role for mRNA secondary structure in the control of translation initiation. Nature, Vol. 295. S. 616-618.

Hall, M. N. and Schwartz, M.. (1982) Reconsidering the early steps of protein secretion. Annales de Microbiologie, Vol. 133a, H. 1. S. 123-127.

Hall, M. N. and Schwartz, M. and Silhavy, T. J.. (1982) Sequence information within the lamB genes in required for proper routing of the bacteriophage lambda receptor protein to the outer membrane of Escherichia coli K-12. Journal of molecular biology, Vol. 156, H. 1. S. 93-112.

1981

Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1981) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. In: Membrane transport and neuroreceptors. New York, S. 81-97.

Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the major outer membrane proteins of Escherichia coli. Annual Review of Genetics, Vol. 15. S. 91-142.

Hall, M. N. and Silhavy, T. J.. (1981) Genetic analysis of the ompB locus in Escherichia coli K-12. Journal of molecular biology, Vol. 151, H. 1. S. 1-15.

Hall, M. N. and Silhavy, T. J.. (1981) The ompB locus and the regulation of the major outer membrane porin proteins of Escherichia coli K12. Journal of molecular biology, Vol. 146, H. 1. S. 23-43.

Taylor, R. K. and Hall, M. N. and Enquist, L. and Silhavy, T. J.. (1981) Identification of OmpR : a positive regulatory protein controlling expression of the major outer membrane matrix porin proteins of Escherichia coli K-12. Journal of bacteriology, Vol. 147, H. 1. S. 255-258.

1980

Emr, S. D. and Hall, M. N. and Silhavy, T. J.. (1980) A mechanism of protein localization : the signal hypothesis and bacteria. The Journal of cell biology, Vol. 86, H. 3. S. 701-711.

Hall, M. N. and Emr, S. D. and Silhavy, T. J.. (1980) Genetic studies on mechanisms of protein localization in Escherichia coli K-12. Journal of Supramolecular Structure, Vol. 13, H. 2. S. 147-163.

Moreno, F. and Fowler, A. V. and Hall, M. and Silhavy, T. J. and Zabin, I. and Schwartz, M.. (1980) A signal sequence is not sufficient to lead beta-galactosidase out of the cytoplasm. Nature, Vol. 286. S. 356-359.

1979

Hall, M. N. and Silhavy, T. J.. (1979) Transcriptional regulation of Escherichia coli K-12 major outer membrane protein 1b. Journal of bacteriology, Vol. 140, H. 2. S. 342-350.

This list was generated on Wed Sep 20 03:54:19 2017 CEST.