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Items where Division is "05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molecular and Systems Toxicology (Odermatt)"

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Number of items at this level: 93.

May 2016

Canonica, Jérémie and Sergi, Chloé and Maillard, Marc and Klusonova, Petra and Odermatt, Alex and Koesters, Robert and Loffing-Cueni, Dominique and Loffing, Johannes and Rossier, Bernard and Frateschi, Simona and Hummler, Edith. (2016) Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype. Pflügers Archiv : European journal of physiology, 468 (5). pp. 895-908.

Mani, Orlando and Nashev, Lyubomir G. and Livelo, Christopher and Baker, Michael E. and Odermatt, Alex. (2016) Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone. The Journal of steroid biochemistry and molecular biology, 159. pp. 31-40.

April 2016

Odermatt, Alex and Strajhar, Petra and Engeli, Roger T.. (2016) Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools. The Journal of steroid biochemistry and molecular biology, 158. pp. 9-21.

Ramming, Thomas and Kanemura, Shingo and Okumura, Masaki and Inaba, Kenji and Appenzeller-Herzog, Christian. (2016) Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover. Redox biology, 7. pp. 14-20.

March 2016

Strajhar, Petra and Schmid, Y. and Liakoni, E. and Dolder, P. C. and Rentsch, K. M. and Kratschmar, Denise V. and Odermatt, Alex and Liechti, Matthias E.. (2016) Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects. Journal of neuroendocrinology, 28 (3). p. 12374.

February 2016

Rizner, Tea Lanisnik and Sasano, Hironobu and Choi, Man Ho and Odermatt, Alex and Adamski, Jerzy. (2016) Recommendations for description and validation for antibodies for research use. The journal of steroid biochemistry and molecular biology, 156. pp. 40-42.

January 2016

Engeli, Roger T. and Rhouma, Bochra Ben and Sager, Christoph P. and Tsachaki, Maria and Birk, Julia and Fakhfakh, Faiza and Keskes, Leila and Belguith, Neila and Odermatt, Alex. (2016) Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development. The Journal of steroid biochemistry and molecular biology, 155. pp. 147-154.

December 2015

Kaserer, Teresa and Beck, Katharina and Akram, Muhamad and Odermatt, Alex and Schuster, Daniela. (2015) Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases. Molecules, 20 (12). pp. 22799-22832.

Shelton, Luke M. and Lister, Adam and Walsh, Joanne and Jenkins, Rosalind E. and Wong, Michael H. L. and Rowe, Cliff and Ricci, Emanuele and Ressel, Lorenzo and Fang, Yongxiang and Demougin, Philippe and Vukojevic, Vanja and O'Neill, Paul M. and Goldring, Christopher E. and Kitteringham, Neil R. and Park, B. Kevin and Odermatt, Alex and Copple, Ian M.. (2015) Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney international, 88 (6). pp. 1261-1273.

1 November 2015

Di Chiara, Marianna and Glaudemans, Bob and Loffing-Cueni, Dominique and Odermatt, Alex and Al-Hasani, Hadi and Devuyst, Olivier and Faresse, Nourdine and Loffing, Johannes. (2015) Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. American journal of physiology. Gastrointestinal and liver physiology, 309 (9). F779-F790.

November 2015

Seibert, Julia K. and Quagliata, Luca and Quintavalle, Cristina and Hammond, Thomas G. and Terracciano, Luigi and Odermatt, Alex. (2015) A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer. Cancer medicine, 4 (11). pp. 1717-1729.

July 2015

Odermatt, Alex and Klusonova, Petra. (2015) 11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story. The journal of steroid biochemistry and molecular biology, 151. pp. 85-92.

Tsachaki, Maria and Birk, Julia and Egert, Aurélie and Odermatt, Alex. (2015) Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1672-1682.

June 2015

Delaunay-Moisan, Agnès and Appenzeller-Herzog, Christian. (2015) The antioxidant machinery of the endoplasmic reticulum: Protection and signaling. Free radical biology & medicine, 83. pp. 341-351.

Ramming, Thomas and Okumura, Masaki and Kanemura, Shingo and Baday, Sefer and Birk, Julia and Moes, Suzette and Spiess, Martin and Jenö, Paul and Bernèche, Simon and Inaba, Kenji and Appenzeller-Herzog, Christian. (2015) A PDI-catalyzed thiol-disulfide switch regulates the production of hydrogen peroxide by human Ero1. Free radical biology & medicine, 83. pp. 361-372.

May 2015

Tonoli, David and Fürstenberger, Cornelia and Boccard, Julien and Hochstrasser, Denis and Jeanneret, Fabienne and Odermatt, Alex and Rudaz, Serge. (2015) Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells. Chemical research in toxicology, 28 (5). pp. 955-966.

April 2015

Vuorinen, Anna and Seibert, Julia and Papageorgiou, Vassilios P. and Rollinger, Judith M. and Odermatt, Alex and Schuster, Daniela and Assimopoulou, Andreana N.. (2015) Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1. Planta medica, 81 (6). pp. 525-532.

2015

Seibert, Julia Katharina. Characterization of the 11β-hydroxysteroid dehydrogenase 1-related short-chain dehydrogenase/reductase DHRS7. 2015, PhD Thesis, University of Basel, Faculty of Science.

Vuorinen, Anna and Odermatt, Alex and Schuster, Daniela. (2015) Reprint of "In silico methods in the discovery of endocrine disrupting chemicals". The Journal of steroid biochemistry and molecular biology, 153 (September 2015). pp. 93-101.

2014

Blüthgen, Nancy. Effects of UV filters (benzophenones and octocrylene) and mifepristone on different life stages of zebrafish (Danio rerio). 2014, PhD Thesis, University of Basel, Faculty of Science.

Chantong, Boonrat. Regulation of microglial cell function by corticosteroids and disruption by organotins. 2014, PhD Thesis, University of Basel, Faculty of Science.

Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells. Toxicology letters, Vol. 230, H. 2. S. 177-187.

Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive G i -proteins in murine BV-2 microglia cells. Journal of neuroinflammation, Vol. 11, H. 1. S. 190.

Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. S. 136-146.

Fürstenberger, Cornelia. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes. 2014, PhD Thesis, University of Basel, Faculty of Science.

Legeza, Balázs and Balázs, Zoltán and Odermatt, Alex. (2014) Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism. FEBS letters, Vol. 588, H. 3. S. 490-496.

Penno, Carlos A. and Morgan, Stuart A. and Rose, Adam J. and Herzig, Stephan and Lavery, Gareth G. and Odermatt, Alex. (2014) 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Molecular metabolism, Vol. 3, H. 5. S. 554-564.

Ramming, Thomas and Hansen, Henning Gram and Nagata, Kazuhiro and Ellgaard, Lars and Appenzeller-Herzog, Christian. (2014) GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum. Free radical biology & medicine, Vol. 70 , S. 106–116.

Seibert, Julia and Hysek, Cédric M. and Penno, Carlos A. and Schmid, Yasmin and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2014) Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects. Neuroendocrinology, Vol. 100, Issue 1. S. 17-25.

Vuorinen, Anna and Engeli, Roger and Meyer, Arne and Bachmann, Fabio and Griesser, Ulrich J. and Schuster, Daniela and Odermatt, Alex. (2014) Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors. Journal of medicinal chemistry, Vol. 57, H. 14. S. 5995-6007.

2013

Appenzeller-Herzog, Christian and Birk, Julia. (2013) Erratum: Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 255 , 1 S..

Birk, Julia and Meyer, Mariangela and Aller, Isabel and Hansen, Henning G. and Odermatt, Alex and Dick, Tobias P. and Meyer, Andreas J. and Appenzeller-Herzog, Christian. (2013) Endoplasmic reticulum : reduced and oxidized glutathione revisited. Journal of cell science, Vol. 126, H. 7. S. 1604-1617.

Birk, Julia and Ramming, Thomas and Odermatt, Alex and Appenzeller-Herzog, Christian. (2013) Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 108 , 10 S.. S. 108.

Boudon, Stéphanie. Characterization of phototoxicity reactions in human and animal skin models. 2013, PhD Thesis, University of Basel, Faculty of Science.

Legeza, Balazs. Generation and utilization of NADPH in the endoplasmic reticulum : novel insight into the role of luminal NADPH in pathophysiological processes. 2013, PhD Thesis, University of Basel, Faculty of Science.

Legeza, Balázs and Balázs, Zoltán and Nashev, Lyubomir G. and Odermatt, Alex. (2013) The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase. Endocrinology, Vol. 154, H. 1. S. 205-213.

Marchais-Oberwinkler, Sandrine and Xu, Kuiying and Wetzel, Marie and Perspicace, Enrico and Negri, Matthias and Meyer, Arne and Odermatt, Alex and Möller, Gabriele and Adamski, Jerzy and Hartmann, Rolf W.. (2013) Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis. Journal of Medicinal Chemistry, Vol. 56, H. 1. S. 167-181.

Meyer, Arne. The role of the endoplasmic reticulum in the metabolism of "xenobiotica". 2013, PhD Thesis, University of Basel, Faculty of Science.

Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Da Cunha, Thierry and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1. Biochemical pharmacology, Vol. 85, H. 9. S. 1370-1378.

Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1. Drug metabolism and disposition, Vol. 41, H. 9. S. 1671-1678.

Montero, Davide and Tachibana, Christine and Rahr Winther, Jakob and Appenzeller-Herzog, Christian. (2013) Intracellular glutathione pools are heterogeneously concentrated. Redox biology, Vol. 1, H. 1. S. 508-513.

Nashev, Lyubomir G. and Atanasov, Atanas G. and Baker, Michael E. and Odermatt, Alex. (2013) Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals. International journal of cell biology, Vol. 2013 , art. 769536.

Pandya, Keyur and Dietrich, David and Seibert, Julia and Vederas, John C. and Odermatt, Alex. (2013) Synthesis of sterically encumbered 11β-aminoprogesterone derivatives and evaluation as 11β-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists. Bioorganic & medicinal chemistry letters, Vol. 21, H. 21. S. 6274-6281.

Penno, C. A. and Arsenijevic, D: Da Cunha and Kullak-Ublick, G. A. and Montani, J.-P. and Odermatt, A.. (2013) Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry. Analytical methods, Vol. 5. S. 1155-1164.

Penno, Carlos A. and Morgan, Stuart A. and Vuorinen, Anna and Schuster, Daniela and Lavery, Gareth G. and Odermatt, Alex. (2013) Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid. Journal of lipid research, Vol. 54, H. 10. S. 2874-2883.

Penno, Carlos Alberto. The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis. 2013, PhD Thesis, University of Basel, Faculty of Science.

Ramming, Thomas and Appenzeller-Herzog, Christian. (2013) Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum. International journal of cell biology, Vol. 2013 , 180906.

Wright, Jordan and Birk, Julia and Haataja, Leena and Liu, Ming and Ramming, Thomas and Weiss, Michael A. and Appenzeller-Herzog, Christian and Arvan, Peter. (2013) Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. Journal of biological chemistry, Vol. 288, H. 43. S. 31010-31018.

2012

Appenzeller-Herzog, Christian. (2012) Updates on "Endoplasmic Reticulum Redox". Antioxidants & redox signaling, Vol. 16, No. 8. S. 760-762.

Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. S. 260.

Fürstenberger, Cornelia and Vuorinen, Anna and Da Cunha, Thierry and Kratschmar, Denise V. and Saugy, Martial and Schuster, Daniela and Odermatt, Alex. (2012) The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation. Toxicological sciences, Vol. 126, H. 2. S. 353-361.

Hansen, Henning Gram and Schmidt, Jonas Damgård and Søltoft, Cecilie Lützen and Ramming, Thomas and Geertz-Hansen, Henrik Marcus and Christensen, Brian and Sørensen, Esben Skipper and Juncker, Agnieszka Sierakowska and Appenzeller-Herzog, Christian and Ellgaard, Lars. (2012) Hyperactivity of the ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. Journal of biological chemistry, Vol. 287, H. 47. S. 39513-39523.

Kratschmar, Denise V. and Calabrese, Diego and Walsh, Jo and Lister, Adam and Birk, Julia and Appenzeller-Herzog, Christian and Moulin, Pierre and Goldring, Chris E. and Odermatt, Alex. (2012) Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells. PLoS one, Vol. 7, H. 5 , e36774.

Meyer, Arne and Strajhar, Petra and Murer, Céline and Da Cunha, Thierry and Odermatt, Alex. (2012) Species-specific differences in the inhibition of human and zebrafish 11β-hydroxysteroid dehydrogenase 2 by thiram and organotins. Toxicology, Vol. 301, H. 1-3. S. 72-78.

Nashev, Lyubomir G. and Vuorinen, Anna and Praxmarer, Lukas and Chantong, Boonrat and Cereghetti, Diego and Winiger, Rahel and Schuster, Daniela and Odermatt, Alex. (2012) Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action. PLoS one, Vol. 7, H. 10 , e46958.

Odermatt, Alex and Kratschmar, Denise V.. (2012) Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases : an overview. Molecular and cellular endocrinology, Vol. 350, H. 2. S. 168-186.

Ramming, Thomas and Appenzeller-Herzog, Christian. (2012) The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more. Antioxidants & redox signaling, Vol. 16, No. 10. S. 1109-1118.

Vacchi-Suzzi, Caterina. MicroRNAs regulatory networks in cardiotoxicity. 2012, PhD Thesis, University of Basel, Faculty of Science.

Veyrat-Durebex, Christelle and Deblon, Nicolas and Caillon, Aurélie and Andrew, Ruth and Altirriba, Jordi and Odermatt, Alex and Rohner-Jeanrenaud, Françoise. (2012) Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue. PLoS one, Vol. 7, H. 3 , e34002.

2011

Appenzeller-Herzog, Christian. (2011) Glutathione- and non-glutathione-based oxidant control in the endoplasmic reticulum. Journal of cell science, Vol. 124, H. 6. S. 847-855.

Blumberg, Bruce and Iguchi, Taisen and Odermatt, Alex. (2011) Endocrine disrupting chemicals. The journal of steroid biochemistry and molecular biology, Vol. 127, H. 1/2. S. 1-3.

Gaware, Rawindra and Khunt, Rupesh and Czollner, Laszlo and Stanetty, Christian and Da Cunha, Thierry and Kratschmar, Denise V. and Odermatt, Alex and Kosma, Paul and Jordis, Ulrich and Classen-Houben, Dirk. (2011) Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 19, H. 6. S. 1866-1880.

Kratschmar, Denise V. and Vuorinen, Anna and Da Cunha, Thierry and Wolber, Gerhard and Classen-Houben, Dirk and Doblhoff, Otto and Schuster, Daniela and Odermatt, Alex. (2011) Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11?-hydroxysteroid dehydrogenase type 2. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. S. 129-142.

Odermatt, Alex. (2011) The Western-style diet : a major risk factor for impaired kidney function and chronic kidney disease. American journal of physiology. Renal Physiology, Vol. 301, H. 5 , F919-931.

Odermatt, Alex and Da Cunha, Thierry and Penno, Carlos A. and Chandsawangbhuwana, Charlie and Reichert, Christian and Wolf, Armin and Dong, Min and Baker, Michael E.. (2011) Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11?-hydroxysteroid dehydrogenase 1. The Biochemical Journal, Vol. 436, H. 3. S. 621-629.

Reichenbach, Stephan and Leunig, Michael and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Bonel, Harald and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Jüni, Peter. (2011) Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage : a cross-sectional study in young men. Arthritis and rheumatism, Vol. 63, H. 12. S. 4023-4030.

Schuster, Daniela and Kowalik, Dorota and Kirchmair, Johannes and Laggner, Christian and Markt, Patrick and Aebischer-Gumy, Christel and Ströhle, Fabian and Möller, Gabriele and Wolber, Gerhard and Wilckens, Thomas and Langer, Thierry and Odermatt, Alex and Adamski, Jerzy. (2011) Identification of chemically diverse, novel inhibitors of 17?-hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. S. 148-161.

2010

Appenzeller-Herzog, Christian and Riemer, Jan and Zito, Ester and Chin, King-Tung and Ron, David and Spiess, Martin and Ellgaard, Lars. (2010) Disulphide production by Ero1alpha-PDI relay is rapid and effectively regulated. The EMBO journal, Vol. 29, H. 19. S. 3318-3329.

Beseda, Igor and Czollner, Laszlo and Shah, Priti S. and Khunt, Rupesh and Gaware, Rawindra and Kosma, Paul and Stanetty, Christian and Del Ruiz-Ruiz, Maria Carmen and Amer, Hassan and Mereiter, Kurt and Da Cunha, Thierry and Odermatt, Alex and Classen-Houben, Dirk and Jordis, Ulrich. (2010) Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases. Bioorganic & medicinal chemistry, Vol. 18, H. 1. S. 433-454.

Nashev, Lyubomir G. and Schuster, Daniela and Laggner, Christian and Sodha, Seloni and Langer, Thierry and Wolber, Gerhard and Odermatt, Alex. (2010) The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals. Biochemical Pharmacology, Vol. 79, Issue 8. S. 1189-1199.

Odermatt, Alex and Nashev, Lyubomir G.. (2010) The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations. The journal of steroid biochemistry and molecular biology, Vol. 119, H. 1-2. S. 1-13.

Reichenbach, Stephan and Jüni, Peter and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Trelle, Sven and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Leunig, Michael. (2010) Prevalence of cam-type deformity on hip magnetic resonance imaging in young males : a cross-sectional study. Arthritis care & research, Vol. 62, H. 9. S. 1319-1327.

Rollinger, Judith M. and Kratschmar, Denise V. and Schuster, Daniela and Pfisterer, Petra H. and Gumy, Christel and Aubry, Evelyne M. and Brandstötter, Sarah and Stuppner, Hermann and Wolber, Gerhard and Odermatt, Alex. (2010) 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorganic & medicinal chemistry, Vol. 18, H. 4. S. 1507-1515.

Senesi, Silvia and Legeza, Balázs and Balázs, Zoltán and Csala, Miklós and Marcolongo, Paola and Kereszturi, Eva and Szelényi, Péter and Egger, Christine and Fulceri, Rosella and Mandl, József and Giunti, Roberta and Odermatt, Alex and Bánhegyi, Gábor and Benedetti, Angelo. (2010) Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum : possible implication in the metabolic syndrome. Endocrinology, Vol. 151, H. 10. S. 4830-4839.

Stanetty, Christian and Czollner, Laszlo and Koller, Iris and Shah, Priti and Gaware, Rawindra and Cunha, Thierry Da and Odermatt, Alex and Jordis, Ulrich and Kosma, Paul and Classen-Houben, Dirk. (2010) Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 18, H. 21. S. 7522-7541.

2009

Aubry, E. M. and Odermatt, A.. (2009) Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities. Endocrinology, Vol. 150, No. 6. S. 2700-2708.

Balazs, Z. and Nashev, L. G. and Chandsawangbhuwana, C. and Baker, M. E. and Odermatt, A.. (2009) Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. Molecular and cellular endocrinology, Vol. 301, H. 1-2. S. 117-122.

Classen-Houben, D. and Schuster, D. and Da Cunha, T. and Odermatt, A. and Wolber, G. and Jordis, U. and Kueenburg, B.. (2009) Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid. The journal of steroid biochemistry and molecular biology, Vol. 113, H. 3-5. S. 248-252.

Dzyakanchuk, A. A. and Balazs, Z. and Nashev, L. G. and Amrein, K. E. and Odermatt, A.. (2009) 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. Molecular and cellular endocrinology, Vol. 301, H. 1-2. S. 137-141.

Gumy, C. and Thurnbichler, C. and Aubry, E. M. and Balazs, Z. and Pfisterer, P. and Baumgartner, L. and Stuppner, H. and Odermatt, A. and Rollinger, J. M.. (2009) Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines. Fitoterapia, Vol. 80, no.3. S. 200-205.

Odermatt, A.. (2009) Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors. Expert opinion on therapeutic patents, Vol. 19, H. 10. S. 1477-1483.

Odermatt, A. and Atanasov, A. G.. (2009) Mineralocorticoid receptors : Emerging complexity and functional diversity. Steroids, Vol. 74, H. 2. S. 163-171.

Riemer, Jan and Appenzeller-Herzog, Christian and Johansson, Linda and Bodenmiller, Bernd and Hartmann-Petersen, Rasmus and Ellgaard, Lars. (2009) A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, H. 35. S. 14831-14836.

2008

Atanasov, Atanas G. and Nashev, Lyubomir G. and Gelman, Laurent and Legeza, Balazs and Sack, Ragna and Portmann, Reto and Odermatt, Alex. (2008) Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen. Biochimica et biophysica acta. Molecular cell research, Vol. 1783, Issue 8. S. 1536-1543.

Balazs, Z. and Schweizer, R. A. and Frey, F. J. and Rohner-Jeanrenaud, F. and Odermatt, A.. (2008) DHEA induces 11beta-HSD2 by acting on CCAAT/enhancer-binding proteins. Journal of the American Society of Nephrology, Vol. 19, H. 1. S. 92-101.

Gumy, C. and Chandsawangbhuwana, C. and Dzyakanchuk, A. A. and Kratschmar, D. V. and Baker, M. E. and Odermatt, A.. (2008) Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production. PLoS one, Vol. 3, H. 10 , e3545.

Kardon, Tamás and Senesi, Silvia and Marcolongo, Paola and Legeza, Balázs and Bánhegyi, Gábor and Mandl, József and Fulceri, Rosella and Benedetti, Angelo. (2008) Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes. FEBS letters, Vol. 582, H. 13. S. 1809-1815.

Odermatt, Alex and Gumy, Christel. (2008) Disruption of glucocorticoid and mineralocorticoid receptor-mediated responses by environmental chemicals. Chimia, Vol. 62, H. 5. S. 335-339.

Odermatt, Alex and Gumy, Christel. (2008) Glucocorticoid and mineralocorticoid action : Why should we consider influences by environmental chemicals? Biochemical Pharmacology, Volume 76, Issue 10. S. 1184-1193.

Schuster, Daniela and Nashev, Lyubomir G. and Kirchmair, Johannes and Laggner, Christian and Wolber, Gerhard and Langer, Thierry and Odermatt, Alex. (2008) Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. Journal of medicinal chemistry, Vol. 51, no. 14. S. 4188-4199.

2007

Atanasov, A. G. and Ignatova, I. D. and Nashev, L. G. and Dick, B. and Ferrari, P. and Frey, F. J. and Odermatt, A.. (2007) Impaired protein stability of 11beta-hydroxysteroid dehydrogenase type : a novel mechanism of apparent mineralocorticoid excess. Journal of the American Society of Nephrology, Vol. 18, H. 4. S. 1262-1270.

Nashev, L. G. and Chandsawangbhuwana, C. and Balazs, Z. and Atanasov, A. G. and Dick, B. and Frey, F. J. and Baker, M. E. and Odermatt, A.. (2007) Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. PLoS one, Vol. 2, H. 6 , e561.

2005

Appenzeller-Herzog, C. and Nyfeler, B. and Burkhard, P. and Santamaria, I. and Lopez-Otin, C. and Hauri, H. -P.. (2005) Carbohydrate- and conformation-dependent cargo capture for ER-exit. Molecular biology of the cell, Vol. 16, H. 3. S. 1258-1267.

This list was generated on Sun Apr 23 03:57:13 2017 CEST.