Items where Author is "Wymann, M. P."

2013

Erhart, D. and Zimmermann, M. and Jacques, O. and Wittwer, M. B. and Ernst, B. and Constable, E. and Zvelebil, M. and Beaufils, F. and Wymann, M. P.. (2013) Chemical development of intracellular protein heterodimerizers. Chemistry & Biology, 20 (4). pp. 549-557.

Barthwal, M. K. and Anzinger, J. J. and Xu, Q. and Bohnacker, T. and Wymann, M. P. and Kruth, H. S.. (2013) Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation. PLoS ONE, Vol. 8, H. 3 , e58054.

Wymann, M. P. and Solinas, G.. (2013) Inhibition of phosphoinositide 3-kinase γ attenuates inflammation, obesity, and cardiovascular risk factors. Annals of the New York Academy of Sciences, Vol. 1280. pp. 44-47.

Wymann, M. P. and Simons, K.. (2013) Membrane dynamics in physiology and disease. The FEBS journal, Vol. 280, H. 12. p. 2729.

Walser, R. and Burke, J. E. and Gogvadze, E. and Bohnacker, T. and Zhang, X. and Hess, D. and Kuenzi, P. and Leitges, M. and Hirsch, E. and Williams, R. L. and Laffargue, M. and Wymann, M. P.. (2013) PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control. PLoS Biology, Vol. 11, H. 6 , e1001587.

Schmidt, C. and Schneble, N. and Muller, J. P. and Bauer, R. and Perino, A. and Marone, R. and Rybalkin, S. D. and Wymann, M. P. and Hirsch, E. and Wetzker, R.. (2013) Phosphoinositide 3-kinase gamma mediates microglial phagocytosis via lipid kinase-independent control of cAMP. Neuroscience, Vol. 233. pp. 44-53.

Collmann, E. and Bohnacker, T. and Marone, R. and Dawson, J. and Rehberg, M. and Stringer, R. and Krombach, F. and Burkhart, C. and Hirsch, E. and Hollingworth, G. J. and Thomas, M. and Wymann, M. P.. (2013) Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergy. Journal of allergy and clinical immunology, Vol. 132, H. 4. pp. 959-968.

2012

Reichel, C. A. and Puhr-Westerheide, D. and Zuchtriegel, G. and Uhl, B. and Berberich, N. and Zahler, S. and Wymann, M. P. and Luckow, B. and Krombach, F.. (2012) C-C motif chemokine CCL3 and canonical neutrophil attractants promote neutrophil extravasation through common and distinct mechanisms. Blood, Vol. 120, H. 4. pp. 880-890.

Harris, S. J. and Ciuclan, L. and Finan, P. M. and Wymann, M. P. and Walker, C. and Westwick, J. and Ward, S. G. and Thomas, M. J.. (2012) Genetic ablation of PI3Kgamma results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels. European journal of immunology, Vol. 42, H. 12. pp. 3394-3404.

Fougerat, A. and Smirnova, N. F. and Gayral, S. and Malet, N. and Hirsch, E. and Wymann, M. P. and Perret, B. and Martinez, L. O. and Douillon, M. and Laffargue, M.. (2012) Key role of PI3Kgamma in monocyte chemotactic protein-1-mediated amplification of PDGF-induced aortic smooth muscle cell migration. British journal of pharmacology, Vol. 166, no. 5. pp. 1643-1653.

Schaefer, T. and Zajonz, A. and Lorentz, P. and Bohnacker, T. and Wymann, M. P. and Schweighoffer, T.. (2012) Luminal decoration of blood vessels by activated perivasal mast cells in allergic rhinitis. Allergy, Vol. 67, H. 4. pp. 510-520.

Wymann, M. P. and Schultz, C.. (2012) The chemical biology of phosphoinositide 3-kinases. ChemBioChem, Vol. 13, H. 14. pp. 2022-2035.

2011

Perino, A. and Ghigo, A. and Ferrero, E. and Morello, F. and Santulli, G. and Baillie, G. S. and Damilano, F. and Dunlop, A. J. and Pawson, C. and Walser, R. and Levi, R. and Altruda, F. and Silengo, L. and Langeberg, L. K. and Neubauer, G. and Heymans, S. and Lembo, G. and Wymann, M. P. and Wetzker, R. and Houslay, M. D. and Iaccarino, G. and Scott, J. D. and Hirsch, E.. (2011) Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ. Molecular cell, Vol. 42, H. 1. pp. 84-95.

Reichel, C. A. and Lerchenberger, M. and Uhl, B. and Rehberg, M. and Berberich, N. and Zahler, S. and Wymann, M. P. and Krombach, F.. (2011) Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature. PLoS ONE, Vol. 6, H. 2 , e17229.

2008

Fougerat, A. and Gayral, S. and Gourdy, P. and Schambourg, A. and Rückle, T. and Schwarz, M. K. and Rommel, C. and Hirsch, E. and Arnal, J. F. and Salles, J. P. and Perret, B. and Breton-Douillon, M. and Wymann, M. P. and Laffargue, M.. (2008) Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes. Circulation, Vol. 117, H. 10. pp. 1310-1317.

Wymann, M. P. and Schneiter, R.. (2008) Lipid signalling in disease. Nature reviews. Molecular cell biology, Vol. 9, H. 2. pp. 162-176.

Ciraolo, E. and Iezzi, M. and Marone, R. and Marengo, S. and Curcio, C. and Costa, C. and Azzolino, O. and Gonella, C. and Rubinetto, C. and Wu, H. and Dastrù, W. and Martin, E. L. and Silengo, L. and Altruda, F. and Turco, E. and Lanzetti, L. and Musiani, P. and Rückle, T. and Rommel, C. and Backer, J. M. and Forni, G. and Wymann, M. P. and Hirsch, E.. (2008) Phosphoinositide 3-kinase p110beta activity : key role in metabolism and mammary gland cancer but not development. Science signaling, Vol. 1, H. 36 , ra3.

Marone, R. and Cmiljanovic, V. and Giese, B. and Wymann, M. P.. (2008) Targeting phosphoinositide 3-kinase-Moving towards therapy. Biochimica et biophysica acta, Vol. 1784, H. 1. pp. 159-185.