Items where Author is "Wichmann, Jürgen"

12 February 2015

Jaeschke, Georg and Kolczewski, Sabine and Spooren, Will and Vieira, Eric and Bitter-Stoll, Nadia and Boissin, Patrick and Borroni, Edilio and Büttelmann, Bernd and Ceccarelli, Simona and Clemann, Nicole and David, Beatrice and Funk, Christoph and Guba, Wolfgang and Harrison, Anthony and Hartung, Thomas and Honer, Michael and Huwyler, Jörg and Kuratli, Martin and Niederhauser, Urs and Pähler, Axel and Peters, Jens-Uwe and Petersen, Ann and Prinssen, Eric and Ricci, Antonio and Rueher, Daniel and Rueher, Marianne and Schneider, Manfred and Spurr, Paul and Stoll, Theodor and Tännler, Daniel and Wichmann, Jürgen and Porter, Richard H. and Wettstein, Joseph G. and Lindemann, Lothar. (2015) Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators: Discovery of 2-Chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (Basimglurant, RO4917523), a Promising Novel Medicine for Psychiatric Diseases. Journal of medicinal chemistry, 58 (3). pp. 1358-1371.

2010

Woltering, Thomas J. and Wichmann, Jürgen and Goetschi, Erwin and Knoflach, Frédéric and Ballard, Theresa M. and Huwyler, Jörg and Gatti, Silvia. (2010) Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives : Part 4. In vivo active potent and selective non-competitive metabotropic glutamate receptor 2/3 antagonists. Bioorganic & medicinal chemistry letters, Vol. 20, H. 23. pp. 6969-6974.

2009

Vieira, Eric and Huwyler, Jörg and Jolidon, Synèse and Knoflach, Frédéric and Mutel, Vincent and Wichmann, Jürgen. (2009) Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers. Bioorganic and Medicinal Chemistry Letters, 19 (6). pp. 1666-1669.

2008

Woltering, Thomas J. and Wichmann, Jürgen and Goetschi, Erwin and Adam, Geo and Kew, James N. C. and Knoflach, Frédéric and Ballard, Theresa M. and Huwyler, Jörg and Mutel, Vincent and Gatti, Silvia. (2008) Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists. Bioorganic and Medicinal Chemistry Letters, 18 (8). pp. 2725-2729.

2007

Jaeschke, Georg and Porter, Richard and Büttelmann, Bernd and Ceccarelli, Simona M. and Guba, Wolfgang and Kuhn, Bernd and Kolczewski, Sabine and Huwyler, Jörg and Mutel, Vincent and Peters, Jens-Uwe and Ballard, Theresa and Prinssen, Eric and Vieira, Eric and Wichmann, Jürgen and Spooren, Will. (2007) Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 17 (5). pp. 1307-1311.