Items where Author is "Wenzler, Tanja"

2018

Wiedemar, Natalie and Graf, Fabrice E. and Zwyer, Michaela and Ndomba, Emiliana and Kunz Renggli, Christina and Cal, Monica and Schmidt, Remo S. and Wenzler, Tanja and Mäser, Pascal. (2018) Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei. Molecular Microbiology, 107 (1). pp. 57-67.

Farahat, Abdelbasset A. and Ismail, Mohamed A. and Kumar, Arvind and Wenzler, Tanja and Brun, Reto and Paul, Ananya and Wilson, W. David and Boykin, David W.. (2018) Indole and benzimidazole bichalcophenes: synthesis, DNA binding and antiparasitic activity. European Journal of Medicinal Chemistry, 143. pp. 1590-1596.

2016

Wenzler, Tanja and Schumann Burkard, Gabriela and S. Schmidt, Remo and Mäser, Pascal and Bergner, Andreas and Roditi, Isabel and Brun, Reto. (2016) A new approach to chemotherapy : drug-induced differentiation kills African trypanosomes. Scientific Reports, 6. p. 22451.

Patrick, Donald A. and Wenzler, Tanja and Yang, Sihyung and Weiser, Patrick T. and Wang, Michael Zhuo and Brun, Reto and Tidwell, Richard R.. (2016) Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense. Bioorganic & medicinal chemistry, 24 (11). pp. 2451-2465.

Farahat, Abdelbasset A. and Bennett-Vaughn, Cheree and Mineva, Ekaterina M. and Kumar, Arvind and Wenzler, Tanja and Brun, Reto and Liu, Yang and Wilson, W. David and Boykin, David W.. (2016) Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI. Bioorganic & medicinal chemistry letters, 26 (24). pp. 5907-5910.

2014

Patrick, Donald A. and Bakunov, Stanislav A. and Bakunova, Svetlana M. and Wenzler, Tanja and Brun, Reto and Tidwell, Richard R.. (2014) Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 22 (1). pp. 559-576.

Wenzler, Tanja and Yang, Sihyung and Patrick, Donald A. and Braissant, Olivier and Ismail, Mohamed A. and Tidwell, Richard R. and Boykin, David W. and Wang, Michael Zhuo and Brun, Reto. (2014) In vitro and In vivo evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness. Antimicrobial agents and chemotherapy, Vol. 58, H. 8. pp. 4452-4463.

Wenzler, Tanja. In vitro studies and in vivo evaluation of novel diamidines for 2nd stage sleeping sickness. 2014, Doctoral Thesis, University of Basel, Faculty of Science.

Yang, Sihyung and Wenzler, Tanja and Miller, Patrik N. and Wu, Huali and Boykin, David W. and Brun, Reto and Wang, Michael Zhuo. (2014) Pharmacokinetic comparison to determine the mechanisms underlying the differential efficacies of cationic diamidines against first- and second-stage human African trypanosomiasis. Antimicrobial agents and chemotherapy, Vol. 58, H. 7. pp. 4064-4074.

Tatipaka, Hari Babu and Gillespie, J. Robert and Chatterjee, Arnab K. and Norcross, Neil R. and Hulverson, Matthew A. and Ranade, Ranae M. and Nagendar, Pendem and Creason, Sharon A. and McQueen, Joshua and Duster, Nicole A. and Nagle, Advait and Supek, Frantisek and Molteni, Valentina and Wenzler, Tanja and Brun, Reto and Glynne, Richard and Buckner, Frederick S. and Gelb, Michael H.. (2014) Substituted 2-phenylimidazopyridines : a new class of drug leads for human African trypanosomiasis. Journal of medicinal chemistry, 57 (3). pp. 828-835.

Liu, Zong-Ying and Wenzler, Tanja and Brun, Reto and Zhu, Xiaohua and Boykin, David W.. (2014) Synthesis and antiparasitic activity of new bis-arylimidamides : DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 83. pp. 167-173.

2013

Malebo, Hamisi M. and Wenzler, Tanja and Cal, Monical and Swaleh, Sauda M. and Hassanali, Ahmed and Sequin, Urs and Machocho, Alex K and Haeussinger, Daniel and Dalsgaard, Petur and Omolo, Maurice O. and Hamburger, Matthias and Brun, Reto and Ndiege, Isaiah O.. (2013) Anti-protozoal and structure-activity relationships of chemical constituents of Acridocarpus chloropterus Oliver (Malpighiaceae) from Tanzania. International Journal of Natural Products Research, 3 (4). pp. 74-81.

Graf, Fabrice E. and Ludin, Philipp and Wenzler, Tanja and Kaiser, Marcel and Brun, Reto and Pyana, Patient Pati and Büscher, Philippe and de Koning, Harry P. and Horn, David and Mäser, Pascal. (2013) Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol. PLoS neglected tropical diseases, Vol. 7, H. 10 , e2475.

Wenzler, Tanja and Yang, Sihyung and Braissant, Olivier and Boykin, David W. and Brun, Reto and Wang, Michael Zhuo. (2013) Pharmacokinetics, Trypanosoma brucei gambiense efficacy, and time of drug action of DB829, a preclinical candidate for treatment of second-stage human African trypanosomiasis. Antimicrobial agents and chemotherapy, Vol. 57, H. 11. pp. 5330-5343.

Patrick, Donald A. and Bakunov, Stanislav A. and Bakunova, Svetlana M. and Jones, Susan Kilgore and Wenzler, Tanja and Barszcz, Todd and Kumar, Arvind and Boykin, David W. and Werbovetz, Karl A. and Brun, Reto and Tidwell, Richard R.. (2013) Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 67. pp. 310-324.

Hu, Laixing and Patel, Alpa and Bondada, Lavanya and Yang, Sihyung and Wang, Michael Zhuo and Munde, Manoj and Wilson, W. David and Wenzler, Tanja and Brun, Reto and Boykin, David W.. (2013) Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues. Bioorganic & medicinal chemistry, 21 (21). pp. 6732-6741.

Patrick, Donald A. and Ismail, Mohamed A. and Arafa, Reem K. and Wenzler, Tanja and Zhu, Xiaohua and Pandharkar, Trupti and Jones, Susan Kilgore and Werbovetz, Karl A. and Brun, Reto and Boykin, David W. and Tidwell, Richard R.. (2013) Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 56 (13). pp. 5473-5494.