Items where Author is "Tidwell, R. R."

2012

Thuita, J. K. and Wang, M. Z. and Kagira, J. M. and Denton, C. L. and Paine, M. F. and Mdachi, R. E. and Murilla, G. A. and Ching, S. and Boykin, D. W. and Tidwell, R. R. and Hall, J. E. and Brun, R.. (2012) Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis. PLoS neglected tropical diseases, Vol. 6, H. 7 , e1734.

2011

Bakunov, S. A. and Bakunova, S. M. and Wenzler, T. and Ghebru, M. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2011) Correction to synthesis and antiprotozoal activity of cationic1,4-diphenyl-1H-1,2,3-triazoles. Journal of medicinal chemistry, 54 (12). p. 4281.

Nehrbass-Stuedli A., and Boykin, D. and Tidwell, R. R. and Brun, R.. (2011) Novel diamidines with activity against Babesia divergens in Vitro and Babesia microti in Vivo. Antimicrobial agents and chemotherapy : AAC, Vol. 55, H. 7. pp. 3439-3445.

Reid, C. S. and Patrick, D. A. and He, S. and Fotie, J. and Premalatha, K. and Tidwell, R. R. and Wang, M. Z. and Liu, Q. and Gershkovich, P. and Wasan, K. M. and Wenzler, T. and Brun, R. and Werbovetz, K. A.. (2011) Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols : effect of core substitutions and salt formation. Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemenination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, 19 (1). pp. 513-523.

2010

Paine, M. F. and Wang, M. Z. and Generaux, C. N. and Boykin, D. W. and Wilson, W. D. and de Koning H. P., and Olson, C. A. and Pohlig, G. and Burri, C. and Brun, R. and Murilla, G. A. and Thuita, J. K. and Barrett, M. P. and Tidwell, R. R.. (2010) Diamidines for human African trypanosomiasis. Current opinion in investigational drugs, Vol. 11, H. 8. pp. 876-883.

Gillingwater, K. and Kumar, A. and Ismail, M. A. and Arafa, R. K. and Stephens, C. E. and Boykin, D. W. and Tidwell, R. R. and Brun, R.. (2010) In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. Veterinary parasitology : an international scientific journal, Vol. 169. pp. 264-272.

Bakunov, S. A. and Bakunova, S. M. and Wenzler, T. and Ghebru, M. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2010) Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. Journal of Medicinal Chemistry, 53 (1). pp. 254-272.

2009

Mdachi, R. E. and Thuita, J. K. and Kagira, J. M. and Ngotho, J. M. and Murilla, G. A. and Ndung'u J. M., and Tidwell, R. R. and Hall, J. E. and Brun, R.. (2009) Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 3. pp. 953-957.

Gillingwater, K. and Kumar, A. and Anbazhagan, M. and Boykin, D. W. and Tidwell, R. R. and Brun, R.. (2009) In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 12. pp. 5074-5079.

Wenzler, T. and Boykin, D. W. and Ismail, M. A. and Hall, J. E. and Tidwell, R. R. and Brun, R.. (2009) New treatment option for second stage African sleeping sickness: In vitro and in vivo efficacy of aza analogs of DB289. Antimicrobial agents and chemotherapy : AAC, Vol. 53, H. 10. pp. 4185-4192.

Bakunova, S. M. and Bakunov, S. A. and Patrick, D. A. and Kumar, E. V. and Ohemeng, K. A. and Bridges, A. S. and Wenzler, T. and Barszcz, T. and Jones, S. K. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2009) Structure-activity study of pentamidine analogues as antiprotozoal agents. Journal of Medicinal Chemistry, 52 (7). pp. 2016-2035.

Patrick, D. A. and Bakunov, S. A. and Bakunova, S. M. and Suresh Kumar E. V., and Chen, H. and Jones, S. K. and Wenzler, T. and Barzcz, T. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2009) Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European Journal of Medicinal Chemistry, 44 (9). pp. 3543-3551.

Bakunova, S. M. and Bakunov, S. A. and Wenzler, T. and Barszcz, T. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2009) Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. Journal of Medicinal Chemistry, 52 (15). pp. 4657-4667.

Bakunov, S. A. and Bakunova, S. M. and Bridges, A. S. and Wenzler, T. and Barszcz, T. and Werbovetz, K. A. and Brun, R. and Tidwell, R. R.. (2009) Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif. Journal of Medicinal Chemistry, 52 (18). pp. 5763-5767.