Items where Author is "Sauerwein, Robert W."

2019

Schalkwijk, Joost and Allman, Erik L. and Jansen, Patrick A. M. and de Vries, Laura E. and Verhoef, Julie M. J. and Jackowski, Suzanne and Botman, Peter N. M. and Beuckens-Schortinghuis, Christien A. and Koolen, Karin M. J. and Bolscher, Judith M. and Vos, Martijn W. and Miller, Karen and Reeves, Stacy A. and Pett, Helmi and Trevitt, Graham and Wittlin, Sergio and Scheurer, Christian and Sax, Sibylle and Fischli, Christoph and Angulo-Barturen, Iñigo and Jiménez-Diaz, Mariá Belén and Josling, Gabrielle and Kooij, Taco W. A. and Bonnert, Roger and Campo, Brice and Blaauw, Richard H. and Rutjes, Floris P. J. T. and Sauerwein, Robert W. and Llinás, Manuel and Hermkens, Pedro H. H. and Dechering, Koen J.. (2019) Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum. Science Translational Medicine, 11 (510). eaas9917.

2017

Paquet, Tanya and Le Manach, Claire and Cabrera, Diego González and Younis, Yassir and Henrich, Philipp P. and Abraham, Tara S. and Lee, Marcus C. S. and Basak, Rajshekhar and Ghidelli-Disse, Sonja and Lafuente-Monasterio, María José and Bantscheff, Marcus and Ruecker, Andrea and Blagborough, Andrew M. and Zakutansky, Sara E. and Zeeman, Anne-Marie and White, Karen L. and Shackleford, David M. and Mannila, Janne and Morizzi, Julia and Scheurer, Christian and Angulo-Barturen, Iñigo and Martínez, María Santos and Ferrer, Santiago and Sanz, Laura María and Gamo, Francisco Javier and Reader, Janette and Botha, Mariette and Dechering, Koen J. and Sauerwein, Robert W. and Tungtaeng, Anchalee and Vanachayangkul, Pattaraporn and Lim, Chek Shik and Burrows, Jeremy and Witty, Michael J. and Marsh, Kennan C. and Bodenreider, Christophe and Rochford, Rosemary and Solapure, Suresh M. and Jiménez-Díaz, María Belén and Wittlin, Sergio and Charman, Susan A. and Donini, Cristina and Campo, Brice and Birkholtz, Lyn-Marie and Hanson, Kirsten K. and Drewes, Gerard and Kocken, Clemens H. M. and Delves, Michael J. and Leroy, Didier and Fidock, David A. and Waterson, David and Street, Leslie J. and Chibale, Kelly. (2017) Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Science translational medicine, 9 (387). eaad9735.

2016

Le Bihan, Amélie and de Kanter, Ruben and Angulo-Barturen, Iñigo and Binkert, Christoph and Boss, Christoph and Brun, Reto and Brunner, Ralf and Buchmann, Stephan and Burrows, Jeremy and Dechering, Koen J. and Delves, Michael and Ewerling, Sonja and Ferrer, Santiago and Fischli, Christoph and Gamo-Benito, Francisco Javier and Gnädig, Nina F. and Heidmann, Bibia and Jiménez-Díaz, María Belén and Leroy, Didier and Martínez, Maria Santos and Meyer, Solange and Moehrle, Joerg J. and Ng, Caroline L. and Noviyanti, Rintis and Ruecker, Andrea and Sanz, Laura María and Sauerwein, Robert W. and Scheurer, Christian and Schleiferboeck, Sarah and Sinden, Robert and Snyder, Christopher and Straimer, Judith and Wirjanata, Grennady and Marfurt, Jutta and Price, Ric N. and Weller, Thomas and Fischli, Walter and Fidock, David A. and Clozel, Martine and Wittlin, Sergio. (2016) Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling. PLoS medicine, 13 (10). e1002138.

2015

Baragaña, Beatriz and Hallyburton, Irene and Lee, Marcus C. S. and Norcross, Neil R. and Grimaldi, Raffaella and Otto, Thomas D. and Proto, William R. and Blagborough, Andrew M. and Meister, Stephan and Wirjanata, Grennady and Ruecker, Andrea and Upton, Leanna M. and Abraham, Tara S. and Almeida, Mariana J. and Pradhan, Anupam and Porzelle, Achim and Martínez, María Santos and Bolscher, Judith M. and Woodland, Andrew and Norval, Suzanne and Zuccotto, Fabio and Thomas, John and Simeons, Frederick and Stojanovski, Laste and Osuna-Cabello, Maria and Brock, Paddy M. and Churcher, Tom S. and Sala, Katarzyna A. and Zakutansky, Sara E. and Jiménez-Díaz, María Belén and Sanz, Laura Maria and Riley, Jennifer and Basak, Rajshekhar and Campbell, Michael and Avery, Vicky M. and Sauerwein, Robert W. and Dechering, Koen J. and Noviyanti, Rintis and Campo, Brice and Frearson, Julie A. and Angulo-Barturen, Iñigo and Ferrer-Bazaga, Santiago and Gamo, Francisco Javier and Wyatt, Paul G. and Leroy, Didier and Siegl, Peter and Delves, Michael J. and Kyle, Dennis E. and Wittlin, Sergio and Marfurt, Jutta and Price, Ric N. and Sinden, Robert E. and Winzeler, Elizabeth A. and Charman, Susan A. and Bebrevska, Lidiya and Gray, David W. and Campbell, Simon and Fairlamb, Alan H. and Willis, Paul A. and Rayner, Julian C. and Fidock, David A. and Read, Kevin D. and Gilbert, Ian H.. (2015) A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature, Vol. 522, H. 7556. pp. 315-320.

Slater, Hannah C. and Ross, Amanda and Ouédraogo, André Lin and White, Lisa J. and Nguon, Chea and Walker, Patrick G. T. and Ngor, Pengby and Aguas, Ricardo and Silal, Sheetal P. and Dondorp, Arjen M. and La Barre, Paul and Burton, Robert and Sauerwein, Robert W. and Drakeley, Chris and Smith, Thomas A. and Bousema, Teun and Ghani, Azra C.. (2015) Assessing the impact of next-generation rapid diagnostic tests on Plasmodium falciparum malaria elimination strategies. Nature, 528 (7580). S94-S101.

Obiero, Joshua M. and Shekalaghe, Seif and Hermsen, Cornelus C. and Mpina, Maxmillian and Bijker, Else M. and Roestenberg, Meta and Teelen, Karina and Billingsley, Peter F. and Sim, B. Kim Lee and James, Eric R. and Daubenberger, Claudia A. and Hoffman, Stephen L. and Abdulla, Salim and Sauerwein, Robert W. and Scholzen, Anja. (2015) Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection. Infection and immunity, Vol. 83, H. 5. pp. 2185-2196.

Richie, Thomas L. and Billingsley, Peter F. and Sim, B. Kim Lee and James, Eric R. and Chakravarty, Sumana and Epstein, Judith E. and Lyke, Kirsten E. and Mordmüller, Benjamin and Alonso, Pedro and Duffy, Patrick E. and Doumbo, Ogobara K. and Sauerwein, Robert W. and Tanner, Marcel and Abdulla, Salim and Kremsner, Peter G. and Seder, Robert A. and Hoffman, Stephen L.. (2015) Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines. Vaccine, 33 (52). pp. 7452-7461.

2014

Shekalaghe, Seif and Rutaihwa, Mastidia and Billingsley, Peter F. and Chemba, Mwajuma and Daubenberger, Claudia A. and James, Eric R. and Mpina, Maximillian and Ali Juma, Omar and Schindler, Tobias and Huber, Eric and Gunasekera, Anusha and Manoj, Anita and Simon, Beatus and Saverino, Elizabeth and Church, L. W. Preston and Hermsen, Cornelus C. and Sauerwein, Robert W. and Plowe, Christopher and Venkatesan, Meera and Sasi, Philip and Lweno, Omar and Mutani, Paul and Hamad, Ali and Mohammed, Ali and Urassa, Alwisa and Mzee, Tutu and Padilla, Debbie and Ruben, Adam and Sim, B. Kim Lee and Tanner, Marcel and Abdulla, Salim and Hoffman, Stephen L.. (2014) Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites. American journal of tropical medicine and hygiene, Vol. 91, H. 3. pp. 471-480.

Kuhen, Kelli L. and Chatterjee, Arnab K. and Rottmann, Matthias and Gagaring, Kerstin and Borboa, Rachel and Buenviaje, Jennifer and Chen, Zhong and Francek, Carolyn and Wu, Tao and Nagle, Advait and Barnes, S. Whitney and Plouffe, David and Lee, Marcus C. S. and Fidock, David A. and Graumans, Wouter and van de Vegte-Bolmer, Marga and van Gemert, Geert J. and Wirjanata, Grennady and Sebayang, Boni and Marfurt, Jutta and Russell, Bruce and Suwanarusk, Rossarin and Price, Ric N. and Nosten, Francois and Tungtaeng, Anchalee and Gettayacamin, Montip and Sattabongkot, Jetsumon and Taylor, Jennifer and Walker, John R. and Tully, David and Patra, Kailash P. and Flannery, Erika L. and Vinetz, Joseph M. and Renia, Laurent and Sauerwein, Robert W. and Winzeler, Elizabeth A. and Glynne, Richard J. and Diagana, Thierry T.. (2014) KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission. Antimicrobial agents and chemotherapy, Vol. 58, H. 9. pp. 5060-5067.

2013

McNamara, Case W. and Lee, Marcus C. S. and Lim, Chek Shik and Lim, Siau Hoi and Roland, Jason and Nagle, Advait and Simon, Oliver and Yeung, Bryan K. S. and Chatterjee, Arnab K. and McCormack, Susan L. and Manary, Micah J. and Zeeman, Anne-Marie and Dechering, Koen J. and Kumar, T. R. Santha and Henrich, Philipp P. and Gagaring, Kerstin and Ibanez, Maureen and Kato, Nobutaka and Kuhen, Kelli L. and Fischli, Christoph and Rottmann, Matthias and Plouffe, David M. and Bursulaya, Badry and Meister, Stephan and Rameh, Lucia and Trappe, Joerg and Haasen, Dorothea and Timmerman, Martijn and Sauerwein, Robert W. and Suwanarusk, Rossarin and Russell, Bruce and Renia, Laurent and Nosten, Francois and Tully, David C. and Kocken, Clemens H. M. and Glynne, Richard J. and Bodenreider, Christophe and Fidock, David A. and Diagana, Thierry T. and Winzeler, Elizabeth A.. (2013) Targeting Plasmodium PI(4)K to eliminate malaria. Nature, Vol. 504, H. 7479. pp. 248-253.