Items where Author is "Read, Kevin D."

2020

Harrison, Justin R. and Sarkar, Sandipan and Hampton, Shahienaz and Riley, Jennifer and Stojanovski, Laste and Sahlberg, Christer and Appelqvist, Pia and Erath, Jessey and Mathan, Vinodhini and Rodriguez, Ana and Kaiser, Marcel and Pacanowska, Dolores Gonzalez and Read, Kevin D. and Johansson, Nils Gunnar and Gilbert, Ian H.. (2020) Discovery and optimization of a compound series active against Trypanosoma cruzi, the causative agent of chagas disease. Journal of medicinal chemistry, 63 (6). pp. 3066-3089.

De Rycker, Manu and Horn, David and Aldridge, Bree and Amewu, Richard K. and Barry, Clifton E. and Buckner, Frederick S. and Cook, Sarah and Ferguson, Michael A. J. and Gobeau, Nathalie and Herrmann, Jennifer and Herrling, Paul and Hope, William and Keiser, Jennifer and Lafuente-Monasterio, Maria Jose and Leeson, Paul D. and Leroy, Didier and Manjunatha, Ujjini H. and McCarthy, James and Miles, Timothy J. and Mizrahi, Valerie and Moshynets, Olena and Niles, Jacquin and Overington, John P. and Pottage, John and Rao, Srinivasa P. S. and Read, Kevin D. and Ribeiro, Isabela and Silver, Lynn L. and Southern, Jen and Spangenberg, Thomas and Sundar, Shyam and Taylor, Caitlin and Van Voorhis, Wes and White, Nicholas J. and Wyllie, Susan and Wyatt, Paul G. and Gilbert, Ian H.. (2020) Setting our sights on infectious diseases. ACS infectious diseases, 6 (1). pp. 3-13.

2019

Baragaña, Beatriz and Forte, Barbara and Choi, Ryan and Nakazawa Hewitt, Stephen and Bueren-Calabuig, Juan A. and Pisco, João Pedro and Peet, Caroline and Dranow, David M. and Robinson, David A. and Jansen, Chimed and Norcross, Neil R. and Vinayak, Sumiti and Anderson, Mark and Brooks, Carrie F. and Cooper, Caitlin A. and Damerow, Sebastian and Delves, Michael and Dowers, Karen and Duffy, James and Edwards, Thomas E. and Hallyburton, Irene and Horst, Benjamin G. and Hulverson, Matthew A. and Ferguson, Liam and Jiménez-Díaz, María Belén and Jumani, Rajiv S. and Lorimer, Donald D. and Love, Melissa S. and Maher, Steven and Matthews, Holly and McNamara, Case W. and Miller, Peter and O'Neill, Sandra and Ojo, Kayode K. and Osuna-Cabello, Maria and Pinto, Erika and Post, John and Riley, Jennifer and Rottmann, Matthias and Sanz, Laura M. and Scullion, Paul and Sharma, Arvind and Shepherd, Sharon M. and Shishikura, Yoko and Simeons, Frederick R. C. and Stebbins, Erin E. and Stojanovski, Laste and Straschil, Ursula and Tamaki, Fabio K. and Tamjar, Jevgenia and Torrie, Leah S. and Vantaux, Amélie and Witkowski, Benoît and Wittlin, Sergio and Yogavel, Manickam and Zuccotto, Fabio and Angulo-Barturen, Iñigo and Sinden, Robert and Baum, Jake and Gamo, Francisco-Javier and Mäser, Pascal and Kyle, Dennis E. and Winzeler, Elizabeth A. and Myler, Peter J. and Wyatt, Paul G. and Floyd, David and Matthews, David and Sharma, Amit and Striepen, Boris and Huston, Christopher D. and Gray, David W. and Fairlamb, Alan H. and Pisliakov, Andrei V. and Walpole, Chris and Read, Kevin D. and Van Voorhis, Wesley C. and Gilbert, Ian H.. (2019) Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (14). pp. 7015-7020.

2016

Baragaña, Beatriz and Norcross, Neil R. and Wilson, Caroline and Porzelle, Achim and Hallyburton, Irene and Grimaldi, Raffaella and Osuna-Cabello, Maria and Norval, Suzanne and Riley, Jennifer and Stojanovski, Laste and Simeons, Frederick R. C. and Wyatt, Paul G. and Delves, Michael J. and Meister, Stephan and Duffy, Sandra and Avery, Vicky M. and Winzeler, Elizabeth A. and Sinden, Robert E. and Wittlin, Sergio and Frearson, Julie A. and Gray, David W. and Fairlamb, Alan H. and Waterson, David and Campbell, Simon F. and Willis, Paul and Read, Kevin D. and Gilbert, Ian H.. (2016) Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy. Journal of medicinal chemistry, 59 (21). pp. 9672-9685.

Russell, Stephanie and Rahmani, Raphaël and Jones, Amy J. and Newson, Harriet L. and Neilde, Kevin and Cotillo, Ignacio and Rahmani Khajouei, Marzieh and Ferrins, Lori and Qureishi, Sana and Nguyen, Nghi and Martinez-Martinez, Maria S. and Weaver, Donald F. and Kaiser, Marcel and Riley, Jennifer and Thomas, John and De Rycker, Manu and Read, Kevin D. and Flematti, Gavin R. and Ryan, Eileen and Tanghe, Scott and Rodriguez, Ana and Charman, Susan A. and Kessler, Albane and Avery, Vicky M. and Baell, Jonathan B. and Piggott, Matthew J.. (2016) Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides. Journal of Medicinal Chemistry, 59 (21). pp. 9686-9720.

Norcross, Neil R. and Baragaña, Beatriz and Wilson, Caroline and Hallyburton, Irene and Osuna-Cabello, Maria and Norval, Suzanne and Riley, Jennifer and Stojanovski, Laste and Simeons, Frederick R. C. and Porzelle, Achim and Grimaldi, Raffaella and Wittlin, Sergio and Duffy, Sandra and Avery, Vicky M. and Meister, Stephan and Sanz, Laura and Jiménez-Díaz, Belén and Angulo-Barturen, Iñigo and Ferrer, Santiago and Martínez, María Santos and Gamo, Francisco Javier and Frearson, Julie A. and Gray, David W. and Fairlamb, Alan H. and Winzeler, Elizabeth A. and Waterson, David and Campbell, Simon F. and Willis, Paul and Read, Kevin D. and Gilbert, Ian H.. (2016) Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials. Journal of Medicinal Chemistry, 59 (13). pp. 6101-6120.

2015

Baragaña, Beatriz and Hallyburton, Irene and Lee, Marcus C. S. and Norcross, Neil R. and Grimaldi, Raffaella and Otto, Thomas D. and Proto, William R. and Blagborough, Andrew M. and Meister, Stephan and Wirjanata, Grennady and Ruecker, Andrea and Upton, Leanna M. and Abraham, Tara S. and Almeida, Mariana J. and Pradhan, Anupam and Porzelle, Achim and Martínez, María Santos and Bolscher, Judith M. and Woodland, Andrew and Norval, Suzanne and Zuccotto, Fabio and Thomas, John and Simeons, Frederick and Stojanovski, Laste and Osuna-Cabello, Maria and Brock, Paddy M. and Churcher, Tom S. and Sala, Katarzyna A. and Zakutansky, Sara E. and Jiménez-Díaz, María Belén and Sanz, Laura Maria and Riley, Jennifer and Basak, Rajshekhar and Campbell, Michael and Avery, Vicky M. and Sauerwein, Robert W. and Dechering, Koen J. and Noviyanti, Rintis and Campo, Brice and Frearson, Julie A. and Angulo-Barturen, Iñigo and Ferrer-Bazaga, Santiago and Gamo, Francisco Javier and Wyatt, Paul G. and Leroy, Didier and Siegl, Peter and Delves, Michael J. and Kyle, Dennis E. and Wittlin, Sergio and Marfurt, Jutta and Price, Ric N. and Sinden, Robert E. and Winzeler, Elizabeth A. and Charman, Susan A. and Bebrevska, Lidiya and Gray, David W. and Campbell, Simon and Fairlamb, Alan H. and Willis, Paul A. and Rayner, Julian C. and Fidock, David A. and Read, Kevin D. and Gilbert, Ian H.. (2015) A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature, Vol. 522, H. 7556. pp. 315-320.

Woodland, Andrew and Thompson, Stephen and Cleghorn, Laura A. T. and Norcross, Neil and De Rycker, Manu and Grimaldi, Raffaella and Hallyburton, Irene and Rao, Bhavya and Norval, Suzanne and Stojanovski, Laste and Brun, Reto and Kaiser, Marcel and Frearson, Julie A. and Gray, David W. and Wyatt, Paul G. and Read, Kevin D. and Gilbert, Ian H.. (2015) Discovery of inhibitors of Trypanosoma brucei by phenotypic screening of a focused protein kinase library. ChemMedChem, 10 (11). pp. 1809-1820.

2013

Murugesan, Dinakaran and Kaiser, Marcel and White, Karen L. and Norval, Suzanne and Riley, Jennifer and Wyatt, Paul G. and Charman, Susan A. and Read, Kevin D. and Yeates, Clive and Gilbert, Ian H.. (2013) Structure-activity relationship studies of pyrrolone antimalarial agents. ChemMedChem : chemistry enabling drug discovery, Vol. 8, H. 9. pp. 1537-1544.