Items where Author is "Nigg, E. A."
Number of items: 135. 2011Jakobsen, L. and Vanselow, K. and Skogs, M. and Toyoda, Y. and Lundberg, E. and Poser, I. and Falkenby, L. G. and Bennetzen, M. and Westendorf, J. and Nigg, E. A. and Uhlen, M. and Hyman, A. A. and Andersen, J. S.. (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. The EMBO journal, Vol. 30. pp. 1520-1535. Alexander, J. and Lim, D. and Joughin, B. A. and Hegemann, B. and Hutchins, J. R. A. and Ehrenberger, T. and Ivins, F. and Sessa, F. and Hudecz, O. and Nigg, E. A. and Fry, A. M. and Musacchio, A. and Stukenberg, P. T. and Mechtler, K. and Peters, J. -M. and Smerdon, S. J. and Yaffe, M. B.. (2011) Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Science Signaling, Vol. 4, H. 179 , ra42. Santamaria, A. and Wang, B. and Elowe, S. and Malik, R. and Zhang, F. and Bauer, M. and Schmidt, A. and Sillje, H. H. and Koerner, R. and Nigg, E. A.. (2011) The Plk1-dependent phosphoproteome of the early mitotic spindle. Molecular & cellular proteomics, Vol. 10, H. 1 , M110.004457. 2010Wang, L. H. -C. and Mayer, B. and Stemmann, O. and Nigg, E. A.. (2010) Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division. Journal of cell science, Vol. 123, H. 5. pp. 806-813. Malik, R. and Dulla, K. and Nigg, E. A. and Korner, R.. (2010) From proteome lists to biological impact tools and strategies for the analysis of large MS data sets. Proteomics, Vol. 10, H. 6. pp. 1270-1283. Guderian, G. and Westendorf, J. and Uldschmid, A. and Nigg, E. A.. (2010) Plk4 trans-autophosphorylation regulates centriole number by controlling betaTrCP-mediated degradation. Journal of cell science, Vol. 123, H. 13. pp. 2163-2169. Olsen, J. V. and Vermeulen, M. and Santamaria, A. and Kumar, C. and Miller, M. L. and Jensen, L. J. and Gnad, F. and Cox, J. and Jensen, T. S. and Nigg, E. A. and Brunak, S. and Mann, M.. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Science Signaling, Vol. 3, H. 104 , ra3. Dulla, K. and Daub, H. and Hornberger, R. and Nigg, E. A. and Korner, R.. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Molecular & cellular proteomics, Vol. 9, H. 6. pp. 1167-1181. Hubner, N. C. and Wang, L. H. and Kaulich, M. and Descombes, P. and Poser, I. and Nigg, E. A.. (2010) Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma, Vol. 119, H. 2. pp. 149-165. von Schubert, C. and Xue, G. and Schmuckli-Maurer, J. and Woods, K. L. and Nigg, E. A. and Dobbelaere, D. A. E.. (2010) The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biology, Vol. 8, H. 9 , e1000499. Elowe, S. and Dulla, K. and Uldschmid, A. and Li, X. and Dou, Z. and Nigg, E. A.. (2010) Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. Journal of cell science, Vol. 123, H. 1. pp. 84-94. 2007Duensing, A. and Liu, Y. and Perdreau, S. A. and Kleylein-Sohn, J. and Nigg, E. A. and Duensing, S.. (2007) Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates. Oncogene, Vol. 26, H. 43. pp. 6280-6288. 2002Meraldi, P. and Nigg, E. A.. (2002) The centrosome cycle. FEBS letters, Vol. 521, H. 1-3. pp. 9-13. Heitlinger, E. and Peter, M. and Lustig, A. and Villiger, W. and Nigg, E. A. and Aebi, U.. (2002) The role of the head and tail domain in lamin structure and assembly : analysis of bacterially expressed chicken lamin A and truncated B2 lamins. Journal of structural biology, Vol. 108, H. 1. pp. 74-89. 2001Nigg, E. A.. (2001) Cell cycle regulation by protein kinases and phosphatases. Ernst Schering Research Foundation workshop, Vol. 34. pp. 19-46. Meraldi, P. and Nigg, E. A.. (2001) Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. Journal of cell science, Vol. 114, H. 20. pp. 3749-3757. Duncan, P. I. and Pollet, N. and Niehrs, C. and Nigg, E. A.. (2001) Cloning and characterization of Plx2 and Plx3, two additional Polo-like kinases from Xenopus laevis. Experimental cell research, Vol. 270, H. 1. pp. 78-87. Silljé, H. H. and Nigg, E. A.. (2001) Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. Current biology, Vol. 11, no. 13. pp. 1068-1073. Nigg, E. A.. (2001) Mitotic kinases as regulators of cell division and its checkpoints. Nature reviews. Molecular cell biology, Vol. 2, H. 1. pp. 21-32. Araújo, S. J. and Nigg, E. A. and Wood, R. D.. (2001) Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome. Molecular and cellular biology, Vol. 21, H. 7. pp. 2281-2291. Donaldson, M. M. and Tavares, A. A. and Hagan, I. M. and Nigg, E. A. and Glover, D. M.. (2001) The mitotic roles of Polo-like kinase. Journal of cell science, Vol. 114, H. 13. pp. 2357-2358. 2000Pahlavan, G. and Polanski, Z. and Kalab, P. and Golsteyn, R. and Nigg, E. A. and Maro, B.. (2000) Characterization of polo-like kinase 1 during meiotic maturation of the mouse oocyte. Developmental biology, Vol. 220, H. 2. pp. 392-400. Smits, V. A. and Klompmaker, R. and Arnaud, L. and Rijksen, G. and Nigg, E. A. and Medema, R. H.. (2000) Polo-like kinase-1 is a target of the DNA damage checkpoint. Nature Cell Biology, Vol. 2, H. 9. pp. 672-676. Fry, A. M. and Mayor, T. and Nigg, E. A.. (2000) Regulating centrosomes by protein phosphorylation. Current topics in developmental biology, Vol. 49. pp. 291-312. Fry, A. M. and Descombes, P. and Twomey, C. and Bacchieri, R. and Nigg, E. A.. (2000) The NIMA-related kinase X-Nek2B is required for efficient assembly of the zygotic centrosome in Xenopus laevis. Journal of cell science, Vol. 113, H. 11. pp. 1973-1984. Mayor, T. and Stierhof, Y. D. and Tanaka, K. and Fry, A. M. and Nigg, E. A.. (2000) The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. The Journal of cell biology, Vol. 151, H. 4. pp. 837-846. 1999Fry, A. M. and Arnaud, L. and Nigg, E. A.. (1999) Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif. Journal of biological chemistry, Vol. 274, H. 23. pp. 16304-16310. Meraldi, P. and Lukas, J. and Fry, A. M. and Bartek, J. and Nigg, E. A.. (1999) Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nature Cell Biology, Vol. 1, H. 2. pp. 88-93. Tanaka, K. and Nigg, E. A.. (1999) Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators. Journal of biological chemistry, Vol. 274, H. 19. pp. 13491-13497. Silljé, H. H. and Takahashi, K. and Tanaka, K. and Van Houwe, G. and Nigg, E. A.. (1999) Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. The EMBO journal, Vol. 18, H. 20. pp. 5691-5702. Mayor, T. and Meraldi, P. and Stierhof, Y. D. and Nigg, E. A. and Fry, A. M.. (1999) Protein kinases in control of the centrosome cycle. FEBS letters, Vol. 452, H. 1/2. pp. 92-95. 1998Fry, A. M. and Meraldi, P. and Nigg, E. A.. (1998) A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators. The EMBO journal, Vol. 17, H. 2. pp. 470-481. Fry, A. M. and Mayor, T. and Meraldi, P. and Stierhof, Y. D. and Tanaka, K. and Nigg, E. A.. (1998) C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. The Journal of cell biology, Vol. 141, H. 7. pp. 1563-1574. Arnaud, L. and Pines, J. and Nigg, E. A.. (1998) GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes. Chromosoma, Vol. 107, H. 6-7. pp. 424-429. Marshall, C. J. and Nigg, E. A.. (1998) Oncogenes and cell proliferation cancer genes : lessons from genetics and biochemistry. Current opinion in genetics & development, Vol. 8, H. 1. pp. 11-13. Nigg, E. A.. (1998) Polo-like kinases : positive regulators of cell division from start to finish. Current opinion in cell biology, Vol. 10, H. 6. pp. 776-783. Blangy, A. and Chaussepied, P. and Nigg, E. A.. (1998) Rigor-type mutation in the kinesin-related protein HsEg5 changes its subcellular localization and induces microtubule bundling. Cell Motility And The Cytoskeleton, Vol. 40, H. 2. pp. 174-182. Descombes, P. and Nigg, E. A.. (1998) The polo-like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. The EMBO Journal, 17 (5). pp. 1328-1335. 1997Lane, H. A. and Nigg, E. A.. (1997) Cell-cycle control : POLO-like kinases join the outer circle. Trends in cell biology, Vol. 7, H. 2. pp. 63-68. Fry, A. M. and Nigg, E. A.. (1997) Characterization of mammalian NIMA-related kinases. Methods in enzymology, vol. 283. pp. 270-282. Nigg, E. A.. (1997) Nucleocytoplasmic transport : signals, mechanisms and regulation. Nature, Vol. 386. pp. 779-787. Mundt, K. E. and Golsteyn, R. M. and Lane, H. A. and Nigg, E. A.. (1997) On the regulation and function of human polo-like kinase 1 (PLK1) : effects of overexpression on cell cycle progression. Biochemical and Biophysical Research Communications, Vol. 239, H. 2. pp. 377-385. Blangy, A. and Arnaud, L. and Nigg, E. A.. (1997) Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150. Journal of biological chemistry, Vol. 272, H. 31. pp. 19418-19424. Tanaka, K. and Parvinen, M. and Nigg, E. A.. (1997) The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. Experimental cell research, Vol. 237, H. 2. pp. 264-274. 1996Lane, H. A. and Nigg, E. A.. (1996) Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes. The Journal of cell biology, Vol. 135, H. 6. pp. 1701-1713. Nigg, E. A.. (1996) Cyclin-dependent kinase 7 : at the cross-roads of transcription, DNA repair and cell cycle control? Current opinion in cell biology, Vol. 8, H. 3. pp. 312-317. Leclerc, V. and Tassan, J. P. and O'Farrell, P. H. and Nigg, E. A. and Léopold, P.. (1996) Drosophila Cdk8, a kinase partner of cyclin C that interacts with the large subunit of RNA polymerase II. Molecular Biology of the Cell, 7 (4). pp. 505-513. Nigg, E. A. and Blangy, A. and Lane, H. A.. (1996) Dynamic changes in nuclear architecture during mitosis : on the role of protein phosphorylation in spindle assembly and chromosome segregation. Experimental cell research, Vol. 229, H. 2. pp. 174-180. Adamczewski, J. P. and Rossignol, M. and Tassan, J. P. and Nigg, E. A. and Moncollin, V. and Egly, J. M.. (1996) MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH. The EMBO journal, Vol. 15, H. 8. pp. 1877-1884. Golsteyn, R. M. and Lane, H. A. and Mundt, K. E. and Arnaud, L. and Nigg, E. A.. (1996) The family of polo-like kinases. Progress in cell cycle research, Vol. 2. pp. 107-114. Gold, M. O. and Tassan, J. P. and Nigg, E. A. and Rice, A. P. and Herrmann, C. H.. (1996) Viral transactivators E1A and VP16 interact with a large complex that is associated with CTD kinase activity and contains CDK8. Nucleic Acids Research, 24 (19). pp. 3771-3777. 1995Ossipow, V. and Tassan, J. P. and Nigg, E. A. and Schibler, U.. (1995) A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell, Vol. 83, H. 1. pp. 137-146. Fry, A. M. and Nigg, E. A.. (1995) Cell cycle : the NIMA kinase joins forces with Cdc2. Current biology, Vol. 5, H. 10. pp. 1122-1125. Zucca, E. and Nigg, E. A.. (1995) Cell cycle regulation and the function of cancer genes. Annals of oncology, Vol. 6, no. 10. pp. 975-978. Golsteyn, R. M. and Mundt, K. E. and Fry, A. M. and Nigg, E. A.. (1995) Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. The Journal of cell biology, Vol. 129, H. 6. pp. 1617-1628. Nigg, E. A.. (1995) Cyclin-dependent protein kinases : key regulators of the eukaryotic cell cycle. Bioessays, Vol. 17, H. 6. pp. 471-480. Tassan, J. P. and Jaquenoud, M. and Léopold, P. and Schultz, S. J. and Nigg, E. A.. (1995) Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, H. 19. pp. 8871-8875. Tassan, J. P. and Jaquenoud, M. and Fry, A. M. and Frutiger, S. and Hughes, G. J. and Nigg, E. A.. (1995) In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. The EMBO journal, Vol. 14, H. 22. pp. 5608-5617. Devault, A. and Martinez, A. M. and Fesquet, D. and Labbé, J. C. and Morin, N. and Tassan, J. P. and Nigg, E. A. and Cavadore, J. C. and Dorée, M.. (1995) MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. The EMBO journal, Vol. 14, H. 20. pp. 5027-5036. Blangy, A. and Lane, H. A. and d'Hérin, P. and Harper, M. and Kress, M. and Nigg, E. A.. (1995) Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell, Vol. 83, H. 7. pp. 1159-1169. Gallant, P. and Fry, A. M. and Nigg, E. A.. (1995) Protein kinases in the control of mitosis : focus on nucleocytoplasmic trafficking. Journal of cell science. Supplement, 19. pp. 21-28. Fry, A. M. and Schultz, S. J. and Bartek, J. and Nigg, E. A.. (1995) Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans. Journal of biological chemistry, Vol. 270 , no. 21. pp. 12899-12905. 1994Mäkelä, T. P. and Tassan, J. P. and Nigg, E. A. and Frutiger, S. and Hughes, G. J. and Weinberg, R. A.. (1994) A cyclin associated with the CDK-activating kinase MO15. Nature, Vol. 371. pp. 254-257. Golsteyn, R. M. and Schultz, S. J. and Bartek, J. and Ziemiecki, A. and Ried, T. and Nigg, E. A.. (1994) Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5. Journal of cell science, Vol. 107, H. 6. pp. 1509-1517. Tassan, J. P. and Schultz, S. J. and Bartek, J. and Nigg, E. A.. (1994) Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). The Journal of cell biology, Vol. 127, H. 2. pp. 467-478. Schultz, S. J. and Fry, A. M. and Sütterlin, C. and Ried, T. and Nigg, E. A.. (1994) Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans. Cell growth & differentiation, Vol. 5, H. 6. pp. 625-635. Gallant, P. and Nigg, E. A.. (1994) Identification of a novel vertebrate cyclin : cyclin B3 shares properties with both A- and B-type cyclins. The EMBO journal, Vol. 13, H. 3. pp. 595-605. Roy, R. and Adamczewski, J. P. and Seroz, T. and Vermeulen, W. and Tassan, J. P. and Schaeffer, L. and Nigg, E. A. and Hoeijmakers, J. H. and Egly, J. M.. (1994) The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell, Vol. 79, H. 6. pp. 1093-1101. Hennekes, H. and Nigg, E. A.. (1994) The role of isoprenylation in membrane attachment of nuclear lamins : a single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties. Journal of cell science, Vol. 107, H. 4. pp. 1019-1029. 1993Nigg, E. A.. (1993) Cellular substrates of p34(cdc2) and its companion cyclin-dependent kinases. Trends in cell biology, Vol. 3, H. 9. pp. 296-301. Schultz, S. J. and Nigg, E. A.. (1993) Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans. Cell growth & differentiation, Vol. 4, H. 10. pp. 821-830. Schmidt-Zachmann, M. S. and Dargemont, C. and Kühn, L. C. and Nigg, E. A.. (1993) Nuclear export of proteins : the role of nuclear retention. Cell, Vol. 74, H. 3. pp. 493-504. Maridor, G. and Gallant, P. and Golsteyn, R. and Nigg, E. A.. (1993) Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits. Journal of cell science, Vol. 106, H. 2. pp. 535-544. Hennekes, H. and Peter, M. and Weber, K. and Nigg, E. A.. (1993) Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2. The Journal of cell biology, Vol. 120, H. 6. pp. 1293-1304. Schmidt-Zachmann, M. S. and Nigg, E. A.. (1993) Protein localization to the nucleolus : a search for targeting domains in nucleolin. Journal of cell science, Vol. 105, H. 3. pp. 799-806. Nigg, E. A.. (1993) Targets of cyclin-dependent protein kinases. Current opinion in cell biology, Vol. 5, H. 2. pp. 187-193. 1992Nigg, E. A.. (1992) Assembly and cell cycle dynamics of the nuclear lamina. Seminars in cell biology, Vol. 3, H. 4. pp. 245-253. Nigg, E. A.. (1992) Assembly-disassembly of the nuclear lamina. Current opinion in cell biology, Vol. 4, H. 1. pp. 105-109. Krek, W. and Maridor, G. and Nigg, E. A.. (1992) Casein kinase II is a predominantly nuclear enzyme. The Journal of cell biology, Vol. 116, H. 1. pp. 43-55. Krek, W. and Nigg, E. A.. (1992) Cell cycle regulation of vertebrate p34cdc2 activity: identification of Thr161 as an essential in vivo phosphorylation site. The New Biologist, Vol. 4, no. 4. pp. 323-329. Gallant, P. and Nigg, E. A.. (1992) Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. The Journal of cell biology, Vol. 117, H. 1. pp. 213-224. Sanghera, J. S. and Peter, M. and Nigg, E. A. and Pelech, S. L.. (1992) Immunological characterization of avian MAP kinases : evidence for nuclear localization. Molecular Biology of the Cell, 3 (7). pp. 775-787. Peter, M. and Chavrier, P. and Nigg, E. A. and Zerial, M.. (1992) Isoprenylation of rab proteins on structurally distinct cysteine motifs. Journal of cell science, Vol. 102, H. 4. pp. 857-865. Peter, M. and Sanghera, J. S. and Pelech, S. L. and Nigg, E. A.. (1992) Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2. European journal of biochemistry, Vol. 205, H. 1. pp. 287-294. Nigg, E. A. and Gallant, P. and Krek, W.. (1992) Regulation of p34cdc2 protein kinase activity by phosphorylation and cyclin binding. Ciba Foundation symposium, 170. pp. 72-84; discussion 84-96. Nigg, E. A. and Kitten, G. T. and Vorburger, K.. (1992) Targeting lamin proteins to the nuclear envelope: the role of CaaX box modifications. Biochemical Society transactions, Vol. 20, H. 2. pp. 500-504. Krek, W. and Marks, J. and Schmitz, N. and Nigg, E. A. and Simanis, V.. (1992) Vertebrate p34cdc2 phosphorylation site mutants : effects upon cell cycle progression in the fission yeast Schizosaccharomyces pombe. Journal of cell science, Vol. 102, H. 1. pp. 43-53. 1991Maridor, G. and Park, W. and Krek, W. and Nigg, E. A.. (1991) Casein kinase II : cDNA sequences, developmental expression, and tissue distribution of mRNAs for alpha, alpha', and beta subunits of the chicken enzyme. Journal of biological chemistry, Vol. 266 , no. 4. pp. 2362-2368. Bailer, S. M. and Eppenberger, H. M. and Griffiths, G. and Nigg, E. A.. (1991) Characterization of A 54-kD protein of the inner nuclear membrane : evidence for cell cycle-dependent interaction with the nuclear lamina. The Journal of cell biology, Vol. 114, H. 3. pp. 389-400. Krek, W. and Nigg, E. A.. (1991) Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle : identification of major phosphorylation sites. The EMBO journal, Vol. 10, H. 2. pp. 305-316. Peter, M. and Heitlinger, E. and Häner, M. and Aebi, U. and Nigg, E. A.. (1991) Disassembly of in vitro formed lamin head-to-tail polymers by CDC2 kinase. The EMBO journal, Vol. 10, H. 6. pp. 1535-1544. Peter, M. and Nigg, E. A.. (1991) Ectopic expression of an A-type lamin does not interfere with differentiation of lamin A-negative embryonal carcinoma cells. Journal of cell science, Vol. 100, H. 3. pp. 589-598. Heitlinger, E. and Peter, M. and Häner, M. and Lustig, A. and Aebi, U. and Nigg, E. A.. (1991) Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions. The Journal of cell biology, Vol. 113, H. 3. pp. 485-495. Pearson, D. and Nigg, E. A. and Nagamine, Y. and Jans, D. A. and Hemmings, B. A.. (1991) Mechanisms of cAMP-mediated gene induction : examination of renal epithelial cell mutants affected in the catalytic subunit of the cAMP-dependent protein kinase. Experimental cell research, Vol. 192, H. 1. pp. 315-318. Krek, W. and Nigg, E. A.. (1991) Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells : evidence for a double block to p34cdc2 kinase activation in vertebrates. The EMBO journal, Vol. 10, H. 11. pp. 3331-3341. Nigg, E. A. and Baeuerle, P. A. and Lührmann, R.. (1991) Nuclear import-export : in search of signals and mechanisms. Cell, Vol. 66, H. 1. pp. 15-22. Kitten, G. T. and Nigg, E. A.. (1991) The CaaX motif is required for isoprenylation, carboxyl methylation, and nuclear membrane association of lamin B2. The Journal of cell biology, Vol. 113, H. 1. pp. 13-23. Nigg, E. A.. (1991) The substrates of the cdc2 kinase. Seminars in cell biology, Vol. 2, H. 4. pp. 261-270. Nigg, E. A. and Krek, W. and Peter, M.. (1991) Vertebrate cdc2 kinase : its regulation by phosphorylation and its mitotic targets. Cold Spring Harbor Symposia on Quantitative Biology, vol. 56. pp. 539-547. Enoch, T. and Peter, M. and Nurse, P. and Nigg, E. A.. (1991) p34cdc2 acts as a lamin kinase in fission yeast. The Journal of cell biology, Vol. 112, H. 5. pp. 797-807. 1990Peter, M. and Nakagawa, J. and Dorée, M. and Labbé, J. C. and Nigg, E. A.. (1990) Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase. Cell, Vol. 60, H. 5. pp. 791-801. Peter, M. and Nakagawa, J. and Dorée, M. and Labbé, J. C. and Nigg, E. A.. (1990) In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase. Cell, Vol. 61, H. 4. pp. 591-602. Nigg, E. A.. (1990) Mechanisms of signal transduction to the cell nucleus. Advances in cancer research, Vol. 55. pp. 271-310. Maridor, G. and Krek, W. and Nigg, E. A.. (1990) Structure and developmental expression of chicken nucleolin and NO38 : coordinate expression of two abundant non-ribosomal nucleolar proteins. Biochimica et biophysica acta, Vol. 1049, H. 2. pp. 126-133. Griffiths, G. and Hollinshead, R. and Hemmings, B. A. and Nigg, E. A.. (1990) Ultrastructural localization of the regulatory (RII) subunit of cyclic AMP-dependent protein kinase to subcellular compartments active in endocytosis and recycling of membrane receptors. Journal of cell science, Vol. 96, H. 4. pp. 691-703. Maridor, G. and Nigg, E. A.. (1990) cDNA sequences of chicken nucleolin/C23 and NO38/B23 : two major nucleolar proteins. Nucleic Acids Research, 18 (5). p. 1286. 1989Vorburger, K. and Lehner, C. F. and Kitten, G. T. and Eppenberger, H. M. and Nigg, E. A.. (1989) A second higher vertebrate B-type lamin : cDNA sequence determination and in vitro processing of chicken lamin B2. Journal of molecular biology, Vol. 208, H. 3. pp. 405-415. Nakagawa, J. and Kitten, G. T. and Nigg, E. A.. (1989) A somatic cell-derived system for studying both early and late mitotic events in vitro. Journal of cell science, Vol. 94, H. 3. pp. 449-462. Peter, M. and Kitten, G. T. and Lehner, C. F. and Vorburger, K. and Bailer, S. M. and Maridor, G. and Nigg, E. A.. (1989) Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. Journal of molecular biology, Vol. 208, H. 3. pp. 393-404. Borer, R. A. and Lehner, C. F. and Eppenberger, H. M. and Nigg, E. A.. (1989) Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell, Vol. 56, H. 3. pp. 379-390. Vorburger, K. and Kitten, G. T. and Nigg, E. A.. (1989) Modification of nuclear lamin proteins by a mevalonic acid derivative occurs in reticulocyte lysates and requires the cysteine residue of the C-terminal CXXM motif. The EMBO journal, Vol. 8, H. 13. pp. 4007-4013. Krek, W. and Nigg, E. A.. 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