Items where Author is "Nashev, Lyubomir G."

May 2016

Mani, Orlando and Nashev, Lyubomir G. and Livelo, Christopher and Baker, Michael E. and Odermatt, Alex. (2016) Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone. The Journal of steroid biochemistry and molecular biology, 159. pp. 31-40.

2014

Vuorinen, Anna and Nashev, Lyubomir G. and Odermatt, Alex and Rollinger, Judith M. and Schuster, Daniela. (2014) Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: Search for modulators of intracellular glucocorticoid concentrations. Molecular Informatics, 33. pp. 15-25.

2013

Nashev, Lyubomir G. and Atanasov, Atanas G. and Baker, Michael E. and Odermatt, Alex. (2013) Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals. International journal of cell biology, Vol. 2013 , art. 769536.

Legeza, Balázs and Balázs, Zoltán and Nashev, Lyubomir G. and Odermatt, Alex. (2013) The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase. Endocrinology, Vol. 154, H. 1. pp. 205-213.

2012

Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. p. 260.

Nashev, Lyubomir G. and Vuorinen, Anna and Praxmarer, Lukas and Chantong, Boonrat and Cereghetti, Diego and Winiger, Rahel and Schuster, Daniela and Odermatt, Alex. (2012) Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action. PLoS ONE, Vol. 7, H. 10 , e46958.

2010

Nashev, Lyubomir G. and Schuster, Daniela and Laggner, Christian and Sodha, Seloni and Langer, Thierry and Wolber, Gerhard and Odermatt, Alex. (2010) The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals. Biochemical Pharmacology, Vol. 79, Issue 8. pp. 1189-1199.

Odermatt, Alex and Nashev, Lyubomir G.. (2010) The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations. The journal of steroid biochemistry and molecular biology, Vol. 119, H. 1-2. pp. 1-13.

2008

Atanasov, Atanas G. and Nashev, Lyubomir G. and Gelman, Laurent and Legeza, Balazs and Sack, Ragna and Portmann, Reto and Odermatt, Alex. (2008) Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen. Biochimica et biophysica acta. Molecular cell research, Vol. 1783, Issue 8. pp. 1536-1543.

Schuster, Daniela and Nashev, Lyubomir G. and Kirchmair, Johannes and Laggner, Christian and Wolber, Gerhard and Langer, Thierry and Odermatt, Alex. (2008) Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. Journal of medicinal chemistry, Vol. 51, no. 14. pp. 4188-4199.