Items where Author is "Lin, Shuo"

20 February 2023

Thürkauf, Marco and Lin, Shuo and Oliveri, Filippo and Grimm, Dirk and Platt, Randall J. and Rüegg, Markus A.. (2023) Fast, multiplexable and highly efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9.

2023

Thürkauf, Marco and Lin, Shuo and Oliveri, Filippo and Grimm, Dirk and Platt, Randall J. and Rüegg, Markus A.. (2023) Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9. Nature communications, 14 (1). p. 6116.

Reinhard, Judith R. and Porrello, Emanuela and Lin, Shuo and Pelczar, Pawel and Previtali, Stefano C. and Rüegg, Markus A.. (2023) Nerve pathology is prevented by linker proteins in mouse models for LAMA2-related muscular dystrophy. PNAS Nexus, 2 (4). pgad083.

19 May 2022

Reinhard, Judith R. and Porrello, Emanuela and Lin, Shuo and Pelczar, Pawel and Previtali, Stefano C. and Rüegg, Markus A.. (2022) Nerve pathology is prevented by linker proteins in mouse models for LAMA2- related muscular dystrophy.

2022

Ham, Daniel J. and Börsch, Anastasiya and Chojnowska, Kathrin and Lin, Shuo and Leuchtmann, Aurel B. and Ham, Alexander S. and Thürkauf, Marco and Delezie, Julien and Furrer, Regula and Burri, Dominik and Sinnreich, Michael and Handschin, Christoph and Tintignac, Lionel A. and Zavolan, Mihaela and Mittal, Nitish and Rüegg, Markus A.. (2022) Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle. Nature Communications, 13. p. 2025.

Kaiser, Marco S. and Milan, Giulia and Ham, Daniel J. and Lin, Shuo and Oliveri, Filippo and Chojnowska, Kathrin and Tintignac, Lionel A. and Mittal, Nitish and Zimmerli, Christian E. and Glass, David J. and Zavolan, Mihaela and Rüegg, Markus A.. (2022) Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis. Communications biology, 5 (1). p. 1141.

30 May 2021

Ham, Daniel J. and Börsch, Anastasyia and Chojnowska, Kathrin and Lin, Shuo and Leuchtmann, Aurel B. and Ham, Alexander S. and Thürkauf, Marco and Delezie, Julien and Furrer, Regula and Burri, Dominik and Sinnreich, Michael and Handschin, Christoph and Tintignac, Lionel A. and Zavolan, Mihaela and Mittal, Nitish and Rüegg, Markus A.. (2021) Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle.

2021

Kaiser, Marco S. and Milan, Giulia and Lin, Shuo and Oliveri, Filippo and Chojnowska, Kathrin and Tintignac, Lionel A. and Mittal, Nitish and Zimmerli, Christian E. and Glass, David J. and Zavolan, Mihaela and Ham, Daniel J. and Rüegg, Markus A.. (2021) Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis. bioRxiv. pp. 1-39.

2020

Pereira, Jorge A. and Gerber, Joanne and Ghidinelli, Monica and Gerber, Daniel and Tortola, Luigi and Ommer, Andrea and Bachofner, Sven and Santarella, Francesco and Tinelli, Elisa and Lin, Shuo and Rüegg, Markus A. and Kopf, Manfred and Toyka, Klaus V. and Suter, Ueli. (2020) Mice carrying an analogous heterozygous Dynamin 2 K562E mutation that causes neuropathy in humans develop predominant characteristics of a primary myopathy. Human Molecular Genetics, 29 (8). pp. 1253-1273.

Ham, Daniel J. and Börsch, Anastasiya and Lin, Shuo and Thürkauf, Marco and Weihrauch, Martin and Reinhard, Judith R. and Delezie, Julien and Battilana, Fabienne and Wang, Xueyong and Kaiser, Marco S. and Guridi, Maitea and Sinnreich, Michael and Rich, Mark M. and Mittal, Nitish and Tintignac, Lionel A. and Handschin, Christoph and Zavolan, Mihaela and Rüegg, Markus A.. (2020) The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia. Nature Communications, 11 (1). p. 4510.

Ham, Alexander S. and Chojnowska, Kathrin and Tintignac, Lionel A. and Lin, Shuo and Schmidt, Alexander and Ham, Daniel J. and Sinnreich, Michael and Rüegg, Markus A.. (2020) mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice. Journal of Cachexia, Sarcopenia and Muscle, 11 (1). pp. 259-273.

2019

Donadon, Irving and Bussani, Erica and Riccardi, Federico and Licastro, Danilo and Romano, Giulia and Pianigiani, Giulia and Pinotti, Mirko and Kostantinova, Pavlina and Evers, Melvin and Lin, Shuo and Rüegg, Markus A. and Pagani, Franco. (2019) Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA. Nucleic acids research, 47 (14). pp. 7618-7632.

Rion, Nathalie and Castets, Perrine and Lin, Shuo and Enderle, Leonie and Reinhard, Judith R. and Eickhorst, Christopher and Rüegg, Markus A.. (2019) mTOR controls embryonic and adult myogenesis via mTORC1. Development, 146 (7). pp. 1-15.

Castets, Perrine and Rion, Nathalie and Théodore, Marine and Falcetta, Denis and Lin, Shuo and Reischl, Markus and Wild, Franziska and Guérard, Laurent and Eickhorst, Christopher and Brockhoff, Marielle and Guridi, Maitea and Ibebunjo, Chikwendu and Cruz, Joseph and Sinnreich, Michael and Rudolf, Rüdiger and Glass, David J. and Rüegg, Markus A.. (2019) mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4. Nature communications, 10 (1). p. 3187.

Rion, Nathalie and Castets, Perrine and Lin, Shuo and Enderle, Leonie and Reinhard, Judith R. and Rüegg, Markus A.. (2019) mTORC2 affects the maintenance of the muscle stem cell pool. Skeletal Muscle, 9 (1). p. 30.

2018

Zainul, Zarin and Heikkinen, Anne and Koivisto, Hennariikka and Rautalahti, Iina and Kallio, Mika and Lin, Shuo and Härönen, Heli and Norman, Oula and Rüegg, Markus A. and Tanila, Heikki and Pihlajaniemi, Taina. (2018) Collagen XIII Is Required for Neuromuscular Synapse Regeneration and Functional Recovery after Peripheral Nerve Injury. The Journal of neuroscience, 38 (17). pp. 4243-4258.

2017

Reinhard, Judith R. and Lin, Shuo and McKee, Karen K. and Meinen, Sarina and Crosson, Stephanie C. and Sury, Maurizio and Hobbs, Samantha and Maier, Geraldine and Yurchenco, Peter D. and Rüegg, Markus A.. (2017) Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice. Science Translational Medicine, 9 (396). eaal4649.

21 March 2016

Guridi, Maitea and Kupr, Barbara and Romanino, Klaas and Lin, Shuo and Falcetta, Denis and Tintignac, Lionel and Rüegg, Markus A.. (2016) Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism. Skeletal Muscle, 6 (13). pp. 1-14.

10 November 2015

Guridi, Maitea and Tintignac, Lionel A. and Lin, Shuo and Kupr, Barbara and Castets, Perrine and Rüegg, Markus A.. (2015) Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21. Science Signaling, 8 (402). ra113.

2015

Zhang, Yina and Lin, Shuo and Karakatsani, Andromachi and Rüegg, Markus A. and Kröger, Stephan. (2015) Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles. European Journal of Neuroscience, 41 (1). pp. 69-78.

2014

Hettwer, Stefan and Lin, Shuo and Kucsera, Stefan and Haubitz, Monika and Oliveri, Filippo and Fariello, Ruggero G. and Ruegg, Markus A. and Vrijbloed, Jan W.. (2014) Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction. PLoS ONE, 9 (2). e88739.

Steiner, Esther and Enzmann, Gaby U. and Lyck, Ruth and Lin, Shuo and Rüegg, Markus A. and Kröger, Stephan and Engelhardt, Britta. (2014) The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell and Tissue Research, 358 (2). pp. 465-479.

2013

Varshney, Gaurav K. and Lu, Jing and Gildea, Derek E. and Huang, Haigen and Pei, Wuhong and Yang, Zhongan and Huang, Sunny C. and Schoenfeld, David and Pho, Nam H. and Casero, David and Hirase, Takashi and Mosbrook-Davis, Deborah and Zhang, Suiyuan and Jao, Li-En and Zhang, Bo and Woods, Ian G. and Zimmerman, Steven and Schier, Alexander F. and Wolfsberg, Tyra G. and Pellegrini, Matteo and Burgess, Shawn M. and Lin, Shuo. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Research, 23 (4). pp. 727-735.

Bentzinger, C. Florian and Lin, Shuo and Romanino, Klaas and Castets, Perrine and Guridi, Maitea and Summermatter, Serge and Handschin, Christoph and Tintignac, Lionel A. and Hall, Michael N. and Rüegg, Markus A.. (2013) Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal Muscle, 3 (1). p. 6.

Cloëtta, Dimitri and Thomanetz, Venus and Baranek, Constanze and Lustenberger, Regula M. and Lin, Shuo and Oliveri, Filippo and Atanasoski, Suzana and Rüegg, Markus A.. (2013) Inactivation of mTORC1 in the Developing Brain Causes Microcephaly and Affects Gliogenesis. Journal of neuroscience, Vol. 33, H. 18. pp. 7799-7810.

Castets, Perrine and Lin, Shuo and Rion, Nathalie and Di Fulvio, Sabrina and Romanino, Klaas and Guridi, Maitea and Frank, Stephan and Tintignac, Lionel A. and Sinnreich, Michael and Ruegg, Markus A.. (2013) Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell metabolism, 17 (5). pp. 731-744.

2012

Meinen, Sarina and Lin, Shuo and Ruegg, Markus A.. (2012) Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A). Skeletal muscle, Vol. 2, H. 1. p. 18.

Meinen, Sarina and Lin, Shuo and Rüegg, Markus A. and Punga, Anna Rostedt. (2012) Fatigue and Muscle Atrophy in a Mouse Model of Myasthenia Gravis Is Paralleled by Loss of Sarcolemmal nNOS. PLoS ONE, Vol. 7, H. 8 , e44148.

Steiner, Esther and Enzmann, Gaby U. and Lin, Shuo and Ghavampour, Sharang and Hannocks, Melanie-Jane and Zuber, Benoît and Rüegg, Markus A. and Sorokin, Lydia and Engelhardt, Britta. (2012) Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia, 60 (11). pp. 1646-1659.

2011

Meinen, Sarina and Lin, Shuo and Thurnherr, Raphael and Erb, Michael and Meier, Thomas and Rüegg, Markus A.. (2011) Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO Molecular Medicine, 3 (8). pp. 465-479.

Romanino, Klaas and Mazelin, Laetitia and Albert, Verena and Conjard-Duplany, Agnès and Lin, Shuo and Bentzinger, C. Florian and Handschin, Christoph and Puigserver, Pere and Zorzato, Francesco and Schaeffer, Laurent and Gangloff, Yann-Gaël and Rüegg, Markus A.. (2011) Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 51. pp. 20808-20813.

2007

Ksiazek, Iwona and Burkhardt, Constanze and Lin, Shuo and Seddik, Riad and Maj, Marcin and Bezakova, Gabriela and Jucker, Mathias and Arber, Silvia and Caroni, Pico and Sanes, Joshua R. and Bettler, Bernhard and Ruegg, Markus A.. (2007) Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. Journal of Neuroscience, 27 (27). pp. 7183-7195.