Items where Author is "Krauth-Siegel, R. Luise"

2019

De Gasparo, Raoul and Halgas, Ondrej and Harangozo, Dora and Kaiser, Marcel and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2019) Targeting a large active site : structure-based design of nanomolar inhibitors of Trypanosoma brucei trypanothione reductase. Chemistry - A European Journal, 25 (49). pp. 11416-11421.

2018

De Gasparo, Raoul and Brodbeck-Persch, Elke and Bryson, Steve and Hentzen, Nina B. and Kaiser, Marcel and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2018) Biological evaluation and x-ray co-crystal structures of cyclohexylpyrrolidine ligands for trypanothione reductase, an enzyme from the redox metabolism of trypanosoma. ChemMedChem, 13 (9). pp. 957-967.

2014

Ayyari, Mahdi and Salehi, Peyman and Ebrahimi, Samad Nejad and Zimmermann, Stefanie and Portmann, Lena and Krauth-Siegel, R. Luise and Kaiser, Marcel and Brun, Reto and Rezadoost, Hassan and Rezazadeh, Shamsali and Hamburger, Matthias. (2014) Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina. Planta Medica, 80 (1). pp. 86-89.

Persch, Elke and Bryson, Steve and Todoroff, Nickolay K. and Eberle, Christian and Thelemann, Jonas and Dirdjaja, Natalie and Kaiser, Marcel and Weber, Maria and Derbani, Hassan and Brun, Reto and Schneider, Gisbert and Pai, Emil F. and Krauth-Siegel, R. Luise and Diederich, François. (2014) Binding to large enzyme pockets : small-molecule inhibitors of trypanothione reductase. ChemMedChem, Vol. 9, H. 8. pp. 1880-1891.

Belluti, Federica and Uliassi, Elisa and Veronesi, Giacomo and Bergamini, Christian and Kaiser, Marcel and Brun, Reto and Viola, Angelo and Fato, Romana and Michels, Paul A. M. and Krauth-Siegel, R. Luise and Cavalli, Andrea and Bolognesi, Maria Laura. (2014) Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi. ChemMedChem : chemistry enabling drug discovery, Vol. 9, H. 2. pp. 371-382.

2013

Zimmermann, Stefanie and Oufir, Mouhssin and Leroux, Alejandro and Krauth-Siegel, R. Luise and Becker, Katja and Kaiser, Marcel and Brun, Reto and Hamburger, Matthias and Adams, Michael. (2013) Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei. Bioorganic & medicinal chemistry, 21 (22). pp. 7202-7209.