Items where Author is "Kaupmann, K."

2001

Pagano, A. and Rovelli, G. and Mosbacher, J. and Lohmann, T. and Duthey, B. and Stauffer, D. and Ristig, D. and Schuler, V. and Meigel, I. and Lampert, C. and Stein, T. and Prezeau, L. and Blahos, J. and Pin, J. and Froestl, W. and Kuhn, R. and Heid, J. and Kaupmann, K. and Bettler, B.. (2001) C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. Journal of neuroscience, Vol. 21, H. 4. pp. 1189-1202.

Schuler, V. and Lüscher, C. and Blanchet, C. and Klix, N. and Sansig, G. and Klebs, K. and Schmutz, M. and Heid, J. and Gentry, C. and Urban, L. and Fox, A. and Spooren, W. and Jaton, A. L. and Vigouret, J. and Pozza, M. and Kelly, P. H. and Mosbacher, J. and Froestl, W. and Käslin, E. and Korn, R. and Bischoff, S. and Kaupmann, K. and van der Putten, H. and Bettler, B.. (2001) Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron, Vol. 31, H. 1. pp. 47-58.

Froestl, W. and Bettler, B. and Bittiger, H. and Heid, J. and Kaupmann, K. and Mickel, S. J. and Strub, D.. (2001) Ligands for expression cloning and isolation of GABA(B) receptors. Il farmaco, Vol. 56, no. 1-2. pp. 101-105.

Urwyler, S. and Mosbacher, J. and Lingenhoehl, K. and Heid, J. and Hofstetter, K. and Froestl, W. and Bettler, B. and Kaupmann, K.. (2001) Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Molecular pharmacology, Vol. 60, H. 5. pp. 963-971.

2000

Galvez, T. and Urwyler, S. and Prézeau, L. and Mosbacher, J. and Joly, C. and Malitschek, B. and Heid, J. and Brabet, I. and Froestl, W. and Bettler, B. and Kaupmann, K. and Pin, J. P.. (2000) Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors : involvement of serine 269 of the GABA(B)R1 subunit. Molecular pharmacology, Vol. 57, H. 3. pp. 419-426.

1999

Pfaff, T. and Malitschek, B. and Kaupmann, K. and Prézeau, L. and Pin, J. P. and Bettler, B. and Karschin, A.. (1999) Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. The European journal of neuroscience, Vol. 11, H. 8. pp. 2874-2882.

Sander, T. and Peters, C. and Kämmer, G. and Samochowiec, J. and Zirra, M. and Mischke, D. and Ziegler, A. and Kaupmann, K. and Bettler, B. and Epplen, J. T. and Riess, O.. (1999) Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy. American journal of medical genetics, Vol. 88, no. 4. pp. 305-310.

Marshall, F. H. and Jones, K. A. and Kaupmann, K. and Bettler, B.. (1999) GABAB receptors - the first 7TM heterodimers. Trends in Pharmacological Sciences, Vol. 20, H. 10. pp. 396-369.

Lingenhoehl, K. and Brom, R. and Heid, J. and Beck, P. and Froestl, W. and Kaupmann, K. and Bettler, B. and Mosbacher, J.. (1999) Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors. Neuropharmacology, Vol. 38, H. 11. pp. 1667-1673.

Froestl, W. and Bettler, B. and Bittiger, H. and Heid, J. and Kaupmann, K. and Mickel, S. J. and Strub, D.. (1999) Ligands for the isolation of GABA(B) receptors [corrected]. Neuropharmacology, Vol. 38, H. 11. pp. 1641-1646.

Galvez, T. and Parmentier, M. L. and Joly, C. and Malitschek, B. and Kaupmann, K. and Kuhn, R. and Bittiger, H. and Froestl, W. and Bettler, B. and Pin, J. P.. (1999) Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding. Journal of biological chemistry, Vol. 274, H. 19. pp. 13362-13369.

Mosbacher, J. and Kaupmann, K. and Schuler, V. and Ristig, D. and Struckmeyer, K. and Pfaff, T. and Karschin, A. and Pozza, M. F. and Bettler, B.. (1999) Processing of GABABR1 in heterologous expression systems. Annals of the New York Academy of Sciences, Vol. 868. pp. 689-692.

Bischoff, S. and Leonhard, S. and Reymann, N. and Schuler, V. and Shigemoto, R. and Kaupmann, K. and Bettler, B.. (1999) Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. The Journal of comparative neurology, Vol. 412, H. 1. pp. 1-16.

Malitschek, B. and Schweizer, C. and Keir, M. and Heid, J. and Froestl, W. and Mosbacher, J. and Kuhn, R. and Henley, J. and Joly, C. and Pin, J. P. and Kaupmann, K. and Bettler, B.. (1999) The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Molecular pharmacology, Vol. 56, H. 2. pp. 448-454.

Franek, M. and Pagano, A. and Kaupmann, K. and Bettler, B. and Pin, J. P. and Blahos, J.. (1999) The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini. Neuropharmacology, Vol. 38, H. 11. pp. 1657-1666.

1998

Malitschek, B. and Rüegg, D. and Heid, J. and Kaupmann, K. and Bittiger, H. and Fröstl, W. and Bettler, B. and Kuhn, R.. (1998) Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain. Molecular and cellular neuroscience, Vol. 12, H. 1-2. pp. 56-64.

Kaupmann, K. and Malitschek, B. and Schuler, V. and Heid, J. and Froestl, W. and Beck, P. and Mosbacher, J. and Bischoff, S. and Kulik, A. and Shigemoto, R. and Karschin, A. and Bettler, B.. (1998) GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature, Vol. 396, H. 6712. pp. 683-687.

Bettler, B. and Kaupmann, K. and Bowery, N.. (1998) GABAB receptors: drugs meet clones. Current opinion in neurobiology, Vol. 8, H. 3. pp. 345-350.

Kaupmann, K. and Schuler, V. and Mosbacher, J. and Bischoff, S. and Bittiger, H. and Heid, J. and Froestl, W. and Leonhard, S. and Pfaff, T. and Karschin, A. and Bettler, B.. (1998) Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels. Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 25. pp. 14991-14996.

Peters, H. C. and Kämmer, G. and Volz, A. and Kaupmann, K. and Ziegler, A. and Bettler, B. and Epplen, J. T. and Sander, T. and Riess, O.. (1998) Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene : evaluation of its involvement in idiopathic generalized epilepsy. Neurogenetics, Vol. 2, H. 1. pp. 47-54.

1997

Kaupmann, K. and Huggel, K. and Heid, J. and Flor, P. J. and Bischoff, S. and Mickel, S. J. and McMaster, G. and Angst, C. and Bittiger, H. and Froestl, W. and Bettler, B.. (1997) Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature, Vol. 386, H. 6622. pp. 239-246.