Items where Author is "Huwyler, J."
Number of items: 35. 2018Schittny, A. and Ogawa, H. and Huwyler, J. and Puchkov, M.. (2018) A Combined Mathematical Model Linking the Formation of Amorphous Solid Dispersions with Hot-Melt-Extrusion Process Parameters. European Journal of Pharmaceutics and Biopharmaceutics, 132. pp. 127-145. Mech, A. and Rasmussen, K. and Jantunen, P. and Aicher, L. and Alessandrelli, M. and Bernauer, U. and Bleeker, E. A. J. and Bouillard, J. and Di Prospero Fanghella, P. and Draisci, R. and Dusinska, M. and Encheva, G. and Flament, G. and Haase, A. and Handzhiyski, Y. and Herzberg, F. and Huwyler, J. and Jacobsen, N. R. and Jeliazkov, V. and Jeliazkova, N. and Nymark, P. and Grafström, R. and Oomen, A. G. and Polci, M. L. and Riebeling, C. and Sandström, J. and Shivachev, B. and Stateva, S. and Tanasescu, S. and Tsekovska, R. and Wallin, H. and Wilks, M. F. and Zellmer, S. and Apostolova, M. D.. (2018) Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation. Nanotoxicology. pp. 1-23. 2016Werk, T. and Ludwig, I. S. and Luemkemann, J. and Huwyler, J. and Mahler, H. -C. and Haeuser, C. R. and Hafner, M.. (2016) New Processes for Freeze-Drying in Dual-Chamber Systems. PDA Journal of Pharmaceutical Science and Technology, 70 (3). pp. 191-207. 2015Mueller, B. and Hieber, S. E. and Zumbuehl, A. and Walter, M. A. and Huwyler, J. and Pfohl, T. and Cattin, Ph. C.. (2015) Translational Medicine: Nanoscience and Nanotechnology to Improve Patient Care. In: The Nano-Micro Interface: Bridging the Micro and Nano Worlds. Weinheim, pp. 291-309. 2014Stirnimann, T. and Atria, S. and Schoelkopf, J. and Gane, P. A. and Alles, R. and Huwyler, J. and Puchkov, M.. (2014) Compaction of functionalized calcium carbonate, a porous and crystalline microparticulate material with a lamellar surface. International journal of pharmaceutics, Vol. 466, H. 1-2 , S. 266–275. Preisig, D. and Haid, D. and Varum, F. J. and Bravo, R. and Huwyler, J. and Puchkov, M.. (2014) Drug loading into porous calcium carbonate microparticles by solvent evaporation. European journal of pharmaceutics and biopharmaceutics, Vol. 87, H. 3. pp. 548-558. Eberle, V. A. and Schoelkopf, J. and Gane, P. A. and Alles, R. and Huwyler, J. and Puchkov, M.. (2014) Floating gastroretentive drug delivery systems : comparison of experimental and simulated dissolution profiles and floatation behavior. European journal of pharmaceutical sciences, Vol. 58. pp. 34-43. Allmendinger, A. and Dieu, L. H. and Fischer, S. and Mueller, R. and Mahler, H. C. and Huwyler, J.. (2014) High-throughput viscosity measurement using capillary electrophoresis instrumentation and its application to protein formulation. Journal of pharmaceutical and biomedical analysis, Vol. 99. pp. 51-58. Kunze, A. and Huwyler, J. and Poller, B. and Gutmann, H. and Camenisch, G.. (2014) In vitro-in vivo extrapolation method to predict human renal clearance of drugs. Journal of pharmaceutical sciences, Vol. 103, H. 3. pp. 994-1001. Camblin, M. and Detampel, P. and Kettiger, H. and Wu, D. and Balasubramanian, V. and Huwyler, J.. (2014) Polymersomes containing quantum dots for cellular imaging. International journal of nanomedicine, Vol. 9. pp. 2287-2298. Kunze, A. and Huwyler, J. and Camenisch, G. and Poller, B.. (2014) Prediction of OATP1B1 and OATP1B3 Mediated Hepatic Uptake of Statins Based on Transporter Protein Expression and Activity Data. Drug metabolism and disposition, Vol. 42, H. 9. pp. 1514-1521. Allmendinger, A. and Fischer, S. and Huwyler, J. and Mahler, H. C. and Schwarb, E. and Zarraga, I. E. and Mueller, R.. (2014) Rheological characterization and injection forces of concentrated protein formulations : an alternative predictive model for non-Newtonian solutions. European journal of pharmaceutics and biopharmaceutics, Vol. 87, H. 2. pp. 318-328. 2013Seeland, S. and Torok, M. and Kettiger, H. and Treiber, A. and Hafner, M. and Huwyler, J.. (2013) A cell-based, multiparametric sensor approach characterises drug-induced cytotoxicity in human liver HepG2 cells. Toxicology in vitro, Vol. 27, H. 3. pp. 1109-1120. Alles, R. and Puchkov, M. and Jablonski, C. and Speich, B. and Keiser, J. and Huwyler, J.. (2013) Development of oxantel tablets for pediatric clinical studies : a technical note. Journal of drug delivery science and technology, Vol. 23, H. 6. pp. 623-625. Kettiger, H. and Schipanski, A. and Wick, P. and Huwyler, J.. (2013) Engineered nanomaterial uptake and tissue distribution : from cell to organism. International journal of nanomedicine, Vol. 8. pp. 3255-3269. Fasler-Kan, E. and Barteneva, N. S. and Ketterer, S. and Wunderlich, K. and Reschner, A. and Nurzhanova, A. and Flammer, J. and Huwyler, J. and Meyer, P.. (2013) Human cytokines activate JAK-STAT signaling pathway in porcine ocular tissue. Xenotransplantation, Vol. 20, H. 6. pp. 469-480. Schoenbaechler, A. and Olfa, G. and Huwyler, J. and Frenz, M. and Pieles, U.. (2013) Indocyanine green loaded biocompatible nanoparticles: Stabilization of indocyanine green (ICG) using biocompatible silica-poly(; e; -caprolactone) grafted nanocomposites. Journal of photochemistry and photobiology. A, Chemistry, Vol. 261. pp. 12-19. 2012Sano, Y. and Kashiwamura, Y. and Abe, M. and Dieu, L. H. and Huwyler, J. and Shimizu, F. and Haruki, H. and Maeda, T. and Saito, K. and Tasaki, A. and Kanda, T.. (2012) A stable human brain microvascular endothelial cell line retaining its barrier-specific nature, independent of the passage number. Clinical and experimental neuroimmunology, Vol. 3. pp. 1-12. Suenderhauf, C. and Hammann, F. and Huwyler, J.. (2012) Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction. Molecules, Vol. 17, H. 9. pp. 10429-10445. Hysek, C. M. and Simmler, L. D. and Nicola, V. G. and Vischer, N. and Donzelli, M. and Krahenbuhl, S. and Grouzmann, E. and Huwyler, J. and Hoener, M. C. and Liechti, M. E.. (2012) Duloxetine inhibits effects of MDMA ("ecstasy") in vitro and in humans in a randomized placebo-controlled laboratory study. PLoS ONE, Vol. 7, H. 5 , e36476. Duthaler, U. and Huwyler, J. and Rinaldi, L. and Cringoli, G. and Keiser, J.. (2012) Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica. Veterinary parasitology, Vol. 186, H. 3-4. pp. 270-280. Kunze, A. and Huwyler, J. and Camenisch, G. and Gutmann, H.. (2012) Interaction of the antiviral drug telaprevir with renal and hepatic drug transporters. Biochemical pharmacology, Vol. 84, Issue 8. pp. 1096-1102. Kirchhofer, C. and Vargas, M. and Huwyler, J. and Keiser, J.. (2012) Pharmacokinetics of the fasciocidal drug candidates MT04 and OZ78 in uninfected rats and in vitro pharmacodynamic studies. International journal for parasitology: drugs and drug resistance, Vol. 2. pp. 121-125. Simmler, L. D. and Buser, T. A. and Donzelli, M. and Schramm, Y. and Dieu, L. H. and Huwyler, J. and Chaboz, S. and Hoener, M. C. and Liechti, M. E.. (2012) Pharmacological characterization of designer cathinones in vitro. British journal of pharmacology, Vol. 168, no. 2. pp. 458-470. 2011Hammann, F. and Suenderhauf, C. and Huwyler, J.. (2011) A Binary Ant Colony Optimization Classifier for Molecular Activities. Journal of Chemical Information and Modeling, Vol. 51. pp. 2690-2696. Seeland, S. and Treiber, A. and Hafner, M. and Huwyler, J.. (2011) On-line identification of P-glycoprotein substrates by monitoring of extracellular acidification and respiration rates in living cells. Biochimica et biophysica acta, Vol. 1808, H. 7. pp. 1827-1831. Schroeder, K. and Bremm, K. D. and Alepee, N. and Bessems, J. G. and Blaauboer, B. and Boehn, S. N. and Burek, C. and Coecke, S. and Gombau, L. and Hewitt, N. J. and Heylings, J. and Huwyler, J. and Jaeger, M. and Jagelavicius, M. and Jarrett, N. and Ketelslegers, H. and Kocina, I. and Koester, J. and Kreysa, J. and Note, R. and Poth, A. and Radtke, M. and Rogiers, V. and Scheel, J. and Schulz, T. and Steinkellner, H. and Toeroek, M. and Whelan, M. and Winkler, P. and Diembeck, W.. (2011) Report from the EPAA workshop : in vitro ADME in safety testing used by EPAA industry sectors. Toxicology in vitro, Vol. 25, H. 3. pp. 589-604. Hysek, C. M. and Simmler, L. D. and Ineichen, M. and Grouzmann, E. and Hoener, M. C. and Brenneisen, R. and Huwyler, J. and Liechti, M. E.. (2011) The Norepinephrine Transporter Inhibitor Reboxetine Reduces Stimulant Effects of MDMA ("Ecstasy") in Humans. Clinical pharmacology and therapeutics, 90 (2). pp. 246-255. 2010Fasler-Kan, E. and Barteneva, N. and Ketterer, S. and Wunderlich, K. and Huwyler, J. and Gygax, D. and Flammer, J. and Meyer, P.. (2010) Activation of the JAK?STAT intracellular pathway in human retinal pigment epithelialcell line ARPE-19. International Journal of Interferon, Cytokine and Mediator Research, Vol. 2. pp. 127-136. Boehringer, M. and Fischer, H. and Hennig, M. and Hunziker, D. and Huwyler, J. and Kuhn, B. and Loeffler, B. M. and Luebbers, T. and Mattei, P. and Narquizian, R. and Sebokova, E. and Sprecher, U. and Wessel, H. P.. (2010) Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors. Bioorganic & medicinal chemistry letters, Vol. 20, H. 3. pp. 1106-1108. Kirchhofer, C. and Keiser, J. and Huwyler, J.. (2010) Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate. Journal of chromatography B, 878 (28). pp. 2770-2774. Mattei, P. and Boehringer, M. and Di Giorgio, P. and Fischer, H. and Hennig, M. and Huwyler, J. and Kocer, B. and Kuhn, B. and Loeffler, B. M. and Macdonald, A. and Narquizian, R. and Rauber, E. and Sebokova, E. and Sprecher, U.. (2010) Discovery of carmegliptin : a potent and long-acting dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Bioorganic & medicinal chemistry letters, Vol. 20, H. 3. pp. 1109-1113. Richter, H. G. and Freichel, C. and Huwyler, J. and Nakagawa, T. and Nettekoven, M. and Plancher, J. M. and Raab, S. and Roche, O. and Schuler, F. and Taylor, S. and Ullmer, C. and Wiegand, R.. (2010) Discovery of potent and selective histamine H3 receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold. Bioorganic & medicinal chemistry letters, Vol. 20, H. 19. pp. 5713-5717. 2008Poller, B. and Gutmann, H. and Krähenbühl, S. and Weksler, B. and Romero, I. and Couraud, P. O. and Tuffin, G. and Drewe, J. and Huwyler, J.. (2008) The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies. Journal of Neurochemistry, Vol. 107, H. 5. pp. 1358-1368. Huwyler, J. and Drewe, J. and Krähenbuhl, S.. (2008) Tumor targeting using liposomal antineoplastic drugs. International Journal of Nanomedicine, 3 (1). pp. 21-29. |
