Items where Author is "Holländer, Georg A."

2014

Sansom, Stephen N. and Shikama-Dorn, Noriko and Zhanybekova, Saule and Nusspaumer, Gretel and Macaulay, Iain C. and Deadman, Mary E. and Heger, Andreas and Ponting, Chris P. and Holländer, Georg A.. (2014) Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. Genome Research, 24 (12). pp. 1918-1931.

2013

Dertschnig, Simone and Nusspaumer, Gretel and Ivanek, Robert and Hauri-Hohl, Mathias M. and Holländer, Georg A. and Krenger, Werner. (2013) Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD. Blood, 122 (5). pp. 837-841.

2012

Zuklys, Saulius and Mayer, Carlos E. and Zhanybekova, Saule and Stefanski, Heather E. and Nusspaumer, Gretel and Gill, Jason and Barthlott, Thomas and Chappaz, Stephane and Nitta, Takeshi and Dooley, James and Nogales-Cadenas, Ruben and Takahama, Yousuke and Finke, Daniela and Liston, Adrian and Blazar, Bruce R. and Pascual-Montano, Alberto and Holländer, Georg A.. (2012) MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection. Journal of immunology (Baltimore, Md. : 1950), 189 (8). pp. 3894-3904.

2011

Krenger, Werner and Blazar, Bruce R. and Holländer, Georg A.. (2011) Thymic T-cell development in allogeneic stem cell transplantation. Blood : the journal of the American Society of Hematology, Vol. 117, H. 25. pp. 6768-6776.

2010

Gossens, Klaus and Naus, Silvia and Holländer, Georg A. and Ziltener, Hermann J.. (2010) Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE, Vol. 5, H. 9 , e12766.

Holländer, Georg A. and Krenger, Werner and Blazar, Bruce R.. (2010) Emerging strategies to boost thymic function. Current opinion in pharmacology, Vol. 10, H. 4. pp. 443-453.

Kenins, Linda and Gill, Jason W. and Holländer, Georg A. and Wodnar-Filipowicz, Aleksandra. (2010) Flt3 ligand-receptor interaction is important for maintenance of early thymic progenitor numbers in steady-state thymopoiesis. European Journal of Immunology, Vol. 40, H. 1. pp. 81-90.

Fayard, Elisabeth and Moncayo, Gerald and Hemmings, Brian A. and Holländer, Georg A.. (2010) Phosphatidylinositol 3-kinase signaling in thymocytes : the need for stringent control. Science signaling, Vol. 3, H. 135 , re5.

Kelly, Ryan M. and Goren, Emily M. and Taylor, Patricia A. and Mueller, Scott N. and Stefanski, Heather E. and Osborn, Mark J. and Scott, Hamish S. and Komarova, Elena A. and Gudkov, Andrei V. and Holländer, Georg A. and Blazar, Bruce R.. (2010) Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation. Blood, Vol. 115, H. 5. pp. 1088-1097.

Saade, Murielle and Irla, Magali and Yammine, Miriam and Boulanger, Nicolas and Victorero, Geneviève and Vincentelli, Renaud and Penninger, Josef M. and Holländer, Georg A. and Chauvet, Sophie and Nguyen, Catherine. (2010) Spatial (Tbata) expression in mature medullary thymic epithelial cells. European Journal of Immunology, Vol. 40, H. 2. pp. 530-538.

Krenger, Werner and Holländer, Georg A.. (2010) The role of the thymus in allogeneic hematopoietic stem cell transplantation. Swiss medical weekly, Vol. 140 , w13051.

Vroegindeweij, Eric and Crobach, Stijn and Itoi, Manami and Satoh, Rumi and Zuklys, Saulius and Happe, Christiane and Germeraad, Wilfred T. V. and Cornelissen, Jan J. and Cupedo, Tom and Holländer, Georg A. and Kawamoto, Hiroshi and van Ewijk, Willem. (2010) Thymic cysts originate from Foxn1 positive thymic medullary epithelium. Molecular immunology, Vol. 47, H. 5. pp. 1106-1113.

2009

Shikama, Noriko and Nusspaumer, Gretel and Holländer, Georg A.. (2009) Clearing the AIRE : on the pathophysiological basis of the autoimmune polyendocrinopathy syndrome type-1. Endocrinology and metabolism clinics of North America, Vol. 38, H. 2 , S. 273-288, vii.

Zuklys, Saulius and Gill, Jason and Keller, Marcel P. and Hauri-Hohl, Mathias and Zhanybekova, Saule and Balciunaite, Gina and Na, Kyung-Jae and Jeker, Lukas T. and Hafen, Katrin and Tsukamoto, Noriyuki and Amagai, Takashi and Taketo, Makoto M. and Krenger, Werner and Holländer, Georg A.. (2009) Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. Journal of immunology : official journal of the American Association of Immunologists, Vol. 182. pp. 2997-3007.

Takahama, Yousuke and Saito, Takashi and Kawamoto, Hiroshi and Itoi, Manami and Boyd, Richard L. and Chidgey, Ann and Zamoyska, Rose and Holländer, Georg A. and Anderson, Graham and Taylor, Naomi and Petrie, Howard T. and Nikolich-Zugich, Janko. (2009) The Global Thymus Network: past, present and future. Trends in immunology, Vol. 30, H. 5. pp. 191-192.

2008

Kelly, Ryan M. and Highfill, Steven L. and Panoskaltsis-Mortari, Angela and Taylor, Patricia A. and Boyd, Richard L. and Holländer, Georg A. and Blazar, Bruce R.. (2008) Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation. Blood, 111 (12). pp. 5734-5744.

Jeker, Lukas Thabo and Barthlott, Thomas and Keller, Marcel P. and Zuklys, Saulius and Hauri-Hohl, Mathias Martin and Deng, Chu-Xia and Holländer, Georg A.. (2008) Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood, 112 (9). pp. 3688-3695.

Hauri-Hohl, Mathias Martin and Zuklys, Saulius and Keller, Marcel P. and Jeker, Lukas T. and Barthlott, Thomas and Moon, Anne M. and Roes, Jürgen and Holländer, Georg A.. (2008) TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. Blood, 112 (3). pp. 626-634.

2005

Wagner, Anna-Margaretha and Beier, Konstantin and Christen, Elli and Holländer, Georg A. and Krenger, Werner. (2005) Leydig cell injury as a consequence of an acute graft-versus-host reaction. Blood, Vol. 105, H. 7. pp. 2988-2890.