Items where Author is "Giese , Bernd"

2017

Beaufils, Florent and Cmiljanovic, Natasa and Cmiljanovic, Vladimir and Bohnacker, Thomas and Melone, Anna and Marone, Romina and Jackson, Eileen and Zhang, Xuxiao and Sele, Alexander and Borsari, Chiara and Mestan, Jurgen and Hebeisen, Paul and Hillmann, Petra and Giese, Bernd and Zvelebil, Marketa and Fabbro, Doriano and Williams, Roger L. and Rageot, Denise and Wymann, Matthias P.. (2017) 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. Journal of Medicinal Chemistry, 60 (17). pp. 7524-7538.

2015

Cmiljanovic, Vladimir and Ettlin, Robert A. and Beautils, Florent and Dieterle, Walter and Hillmann, Petra and Mestan, Juergen and Melone, Anna and Bohnacker, Thomas and Lang, Marc and Cmiljanovic, Natasa and Giese, Bernd and Hebeisen, Paul and Wymann, Matthias P. and Fabbro, Doriano. (2015) PQR309: A potent, brain-penetrant, dual pan-PI3K/mTOR inhibitor with excellent oral bioavailability and tolerability. Cancer Research, 75 (15). p. 4514.

Cmiljanovic, Vladimir and Cmiljanovic, Natasa and Marone, Romina and Beaufils, Florent and Zhang, Xuxiao and Zvelebil, Marketa and Hebeisen, Paul and Lang, Marc and Mestan, Juergen and Melone, Anna and Bohnacker, Thomas and Gaudio, Eugenio and Tarantelli, Chiara and Bertoni, Francesco and Ritschard, Reto and Pretre, Vincent and Wicki, Andreas and Fabbro, Doriano and Hillmann, Petra and Williams, Roger and Giese, Bernd and Wymann, Matthias P.. (2015) PQR309: Structure-based design, synthesis and biological evaluation of a novel, selective, dual pan-PI3K/mTOR inhibitor. Cancer Research, 75 (15). p. 2664.

2010

Constable, Edwin C. and Housecroft, Catherine E. and Creus, Marc and Gademann, Karl and Giese , Bernd and Ward, Thomas R. and Woggon, Wolf-D. and Chougnet, Antoinette. (2010) Bioorganic and bioinorganic chemistry. Chimia, 64 (12). pp. 847-848.

2009

Wang, Min and Gao, Jian and Müller, Pavel and Giese, Bernd. (2009) Electron Transfer in Peptides with Cysteine and Methionine as Relay Amino Acids. Angewandte Chemie International Edition, 48 (23). pp. 4232-4234.

Giese, Bernd and Wang, Min and Gao, Jian and Stoltz, Moritz and Müller, Pavel and Graber, Michael. (2009) Electron relay race in peptides. The journal of organic chemistry, Vol. 74, H. 10 , S. 3621–3625.

Cordes, Meike and Giese, Bernd. (2009) Electron transfer in peptides and proteins. Chemical Society reviews, Vol. 38. pp. 892-901.

Marone, Romina and Erhart, Dominik and Mertz, Ann C. and Bohnacker, Thomas and Schnell, Christian and Cmiljanovic, Vladimir and Stauffer, Frédéric and Garcia-Echeverria, Carlos and Giese, Bernd and Maira, Sauveur-Michel and Wymann, Matthias P.. (2009) Targeting melanoma with dual phosphoinosite 3-kinase/mammalian target of rapamycin inhibitors. Molecular Cancer Research, Vol. 7. pp. 601-613.

2008

Cordes, Meike and Jacques, Olivier and Koettgen, Agnieszka and Jasper, Christian and Boudebous, Hassen and Giese, Bernd. (2008) Development of a model system for the study of long distance electron transfer in peptides. Advanced synthesis & catalysis, Vol. 350. pp. 1053-1062.

Cordes, Meike and Koettgen, Angnieszka and Jasper, Christian and Jacques, Olivier and Boudebous, Hassen and Giese, Bernd. (2008) Influence of amino acid side chains on long-distance electron transfer in peptides : electron hopping via "Stepping Stones". Angewandte Chemie. International edition in English, Vol. 47, H. 18. pp. 3461-3463.

2007

Thoeni, Sandra and Kressierer, Christoph J. and Giese, Bernd. (2007) Site-specific DNA cleavage on a solid support: A method for mismatch detection. Angewandte Chemie. International edition in English, Vol. 46, H. 12. pp. 2112-2114.

2006

Amiot, Nicolas and Heintz, Karine and Giese, Bernd. (2006) New approach for the synthesis of c-di-GMP and its analogues. Synthesis, 2006, H. 24. pp. 4230-4236.