Items where Author is "Botha, Mariette"

2017

Paquet, Tanya and Le Manach, Claire and Cabrera, Diego González and Younis, Yassir and Henrich, Philipp P. and Abraham, Tara S. and Lee, Marcus C. S. and Basak, Rajshekhar and Ghidelli-Disse, Sonja and Lafuente-Monasterio, María José and Bantscheff, Marcus and Ruecker, Andrea and Blagborough, Andrew M. and Zakutansky, Sara E. and Zeeman, Anne-Marie and White, Karen L. and Shackleford, David M. and Mannila, Janne and Morizzi, Julia and Scheurer, Christian and Angulo-Barturen, Iñigo and Martínez, María Santos and Ferrer, Santiago and Sanz, Laura María and Gamo, Francisco Javier and Reader, Janette and Botha, Mariette and Dechering, Koen J. and Sauerwein, Robert W. and Tungtaeng, Anchalee and Vanachayangkul, Pattaraporn and Lim, Chek Shik and Burrows, Jeremy and Witty, Michael J. and Marsh, Kennan C. and Bodenreider, Christophe and Rochford, Rosemary and Solapure, Suresh M. and Jiménez-Díaz, María Belén and Wittlin, Sergio and Charman, Susan A. and Donini, Cristina and Campo, Brice and Birkholtz, Lyn-Marie and Hanson, Kirsten K. and Drewes, Gerard and Kocken, Clemens H. M. and Delves, Michael J. and Leroy, Didier and Fidock, David A. and Waterson, David and Street, Leslie J. and Chibale, Kelly. (2017) Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Science translational medicine, 9 (387). eaad9735.

Singh, Kawaljit and Okombo, John and Brunschwig, Christel and Ndubi, Ferdinand and Barnard, Linley and Wilkinson, Chad and Njogu, Peter M. and Njoroge, Mathew and Laing, Lizahn and Machado, Marta and Prudêncio, Miguel and Reader, Janette and Botha, Mariette and Nondaba, Sindisiwe and Birkholtz, Lyn-Marie and Lauterbach, Sonja and Churchyard, Alisje and Coetzer, Theresa L. and Burrows, Jeremy N. and Yeates, Clive and Denti, Paolo and Wiesner, Lubbe and Egan, Timothy J. and Wittlin, Sergio and Chibale, Kelly. (2017) Antimalarial pyrido[1,2-a]benzimidazoles : lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and in vivo oral efficacy in a mouse model. Journal of medicinal chemistry, 60 (4). pp. 1432-1448.

2015

Le Manach, Claire and Paquet, Tanya and Brunschwig, Christel and Njoroge, Mathew and Han, Ze and Gonzàlez Cabrera, Diego and Bashyam, Sridevi and Dhinakaran, Rajkumar and Taylor, Dale and Reader, Janette and Botha, Mariette and Churchyard, Alisje and Lauterbach, Sonja and Coetzer, Theresa L. and Birkholtz, Lyn-Marie and Meister, Stephan and Winzeler, Elizabeth A. and Waterson, David and Witty, Michael J. and Wittlin, Sergio and Jiménez-Díaz, María-Belén and Santos Martínez, María and Ferrer, Santiago and Angulo-Barturen, Iñigo and Street, Leslie J. and Chibale, Kelly. (2015) A novel pyrazolopyridine with in vivo activity in Plasmodium berghei- and Plasmodium falciparum-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyridazines. Journal of medicinal chemistry, 58 (21). pp. 8713-8722.