Items where Author is "Avery, V. M."

2022

Sykes, M. L. and Kennedy, E. K. and Read, K. D. and Kaiser, M. and Avery, V. M.. (2022) Temporal and wash-out studies identify medicines for malaria venture pathogen box compounds with fast-acting activity against both Trypanosoma cruzi and Trypanosoma brucei. Microorganisms, 10 (7). p. 1287.

2021

Laleu, B. and Akao, Y. and Ochida, A. and Duffy, S. and Lucantoni, L. and Shackleford, D. M. and Chen, G. and Katneni, K. and Chiu, F. C. K. and White, K. L. and Chen, X. and Sturm, A. and Dechering, K. J. and Crespo, B. and Sanz, L. M. and Wang, B. and Wittlin, S. and Charman, S. A. and Avery, V. M. and Cho, N. and Kamaura, M.. (2021) Discovery and structure-activity relationships of quinazolinone-2-carboxamide derivatives as novel orally efficacious antimalarials. Journal of medicinal chemistry, 64 (17). pp. 12582-12602.

Brown, R. W. and Abdel-Megeed, A. M. and Keller, P. A. and Jones, A. J. and Sykes, M. L. and Kaiser, M. and Baell, J. B. and Avery, V. M. and Hyland, C. J. T.. (2021) Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness. RSC Medicinal Chemistry, 11 (12). pp. 1413-1422.

Okaniwa, M. and Shibata, A. and Ochida, A. and Akao, Y. and White, K. L. and Shackleford, D. M. and Duffy, S. and Lucantoni, L. and Dey, S. and Striepen, J. and Yeo, T. and Mok, S. and Aguiar, A. C. C. and Sturm, A. and Crespo, B. and Sanz, L. M. and Churchyard, A. and Baum, J. and Pereira, D. B. and Guido, R. V. C. and Dechering, K. J. and Wittlin, S. and Uhlemann, A. C. and Fidock, D. A. and Niles, J. C. and Avery, V. M. and Charman, S. A. and Laleu, B.. (2021) Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as Plasmodium cytoplasmic prolyl-trna synthetase inhibitors. ACS Infect Dis, 7 (6). pp. 1680-1689.

2015

Manos-Turvey, A. and Watson, E. E. and Sykes, M. L. and Jones, A. J. and Baell, J. B. and Kaiser, M. and Avery, V. M. and Payne, R. J.. (2015) Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. MedChemComm, Vol. 6, H. 3. pp. 403-406.

2012

Edlin, C. D. and Morgans, G. and Winks, S. and Duffy, S. and Avery, V. M. and Wittlin, S. and Waterson, D. and Burrows, J. and Bryans, J.. (2012) Identification and in-vitro ADME assessment of a series of novel anti-malarial agents suitable for hit-to-lead chemistry. ACS medicinal chemistry letters, Vol. 3, H. 7. pp. 570-573.

Sykes, M. L. and Baell, J. B. and Kaiser, M. and Chatelain, E. and Moawad, S. R. and Ganame, D. and Ioset, J. R. and Avery, V. M.. (2012) Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign. PLoS neglected tropical diseases, Vol. 6, H. 11 , e1896.