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Items where contributor is "Vargas, Mireille"

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2018

Wu, Jianbo and Wang, Chunkai and Leas, Derek and Vargas, Mireille and White, Karen L. and Shackleford, David M. and Chen, Gong and Sanford, Austin G. and Hemsley, Ryan M. and Davis, Paul H. and Dong, Yuxiang and Charman, Susan A. and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2018) Progress in antischistosomal N,N'-diaryl urea SAR. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, 28 (3). pp. 244-248.

2017

Tritten, Lucienne and Tam, Mifong and Vargas, Mireille and Jardim, Armando and Stevenson, Mary M. and Keiser, Jennifer and Geary, Timothy G.. (2017) Excretory/secretory products from the gastrointestinal nematode Trichuris muris. Experimental parasitology, 178. pp. 30-36.

Okombo, John and Singh, Kawaljit and Mayoka, Godfrey and Ndubi, Ferdinand and Barnard, Linley and Njogu, Peter M. and Njoroge, Mathew and Gibhard, Liezl and Brunschwig, Christel and Vargas, Mireille and Keiser, Jennifer and Egan, Timothy J. and Chibale, Kelly. (2017) Antischistosomal activity of pyrido[1,2-a]benzimidazole derivatives and correlation with inhibition of beta-hematin formation. ACS Infectious Diseases, 3 (6). pp. 411-420.

Kovač, Jana and Vargas, Mireille and Keiser, Jennifer. (2017) In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium. Parasites and Vectors, 10. p. 365.

Abla, Nada and Keiser, Jennifer and Vargas, Mireille and Reimers, Natalie and Haas, Helmut and Spangenberg, Thomas. (2017) Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model. PLoS neglected tropical diseases, 11 (9). e0005942.

2016

Keiser, Jennifer and Panic, Gordana and Adelfio, Roberto and Cowan, Noemi and Vargas, Mireille and Scandale, Ivan. (2016) Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections. Parasites and Vectors, 9. p. 376.

Cowan, Noemi and Vargas, Mireille and Keiser, Jennifer. (2016) In vitro and in vivo drug interaction Ssudy of two lead combinations, oxantel pamoate plus albendazole and albendazole plus mebendazole, for the treatment of soil-transmitted helminthiasis. Antimicrobial agents and chemotherapy, 60 (10). pp. 6127-6133.

Khan, M. O. Faruk and Keiser, Jennifer and Amoyaw, P. N. A. and Hossain, Mohammad F. and Vargas, Mireille and Le, Justin G. and Simpson, Natalie C. and Roewe, Kimberly D. and Freeman, TaRynn N. Carder and Hasley, Travis R. and Maples, Randall D. and Archibald, Stephen J. and Hubin, Timothy J.. (2016) Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes. Antimicrobial agents and chemotherapy, 60 (9). pp. 5331-5336.

Leonidova, Anna and Vargas, Mireille and Huwyler, Jörg and Keiser, Jennifer. (2016) Pharmacokinetics of the antischistosomal lead OZ418 in uninfected mice determined by LC-MS/MS. Antimicrobial agents and chemotherapy, 60 (12). pp. 7364-7371.

2015

Keiser, Jennifer and Panic, Gordana and Vargas, Mireille and Wang, Chunkai and Dong, Yuxiang and Gautam, Nagsen and Vennerstrom, Jonathan L.. (2015) Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal. The journal of antimicrobial chemotherapy, Vol. 70, H. 6. pp. 1788-1797.

Panic, Gordana and Vargas, Mireille and Scandale, Ivan and Keiser, Jennifer. (2015) Activity profile of an FDA-approved compound library against Schistosoma mansoni. PLoS neglected tropical diseases, Vol. 9, H. 7 , e0003962.

2014

Ingram-Sieber, Katrin and Cowan, Noemi and Panic, Gordana and Vargas, Mireille and Mansour, Nuha R. and Bickle, Quentin D. and Wells, Timothy N. C. and Spangenberg, Thomas and Keiser, Jennifer. (2014) Orally active antischistosomal early leads identified from the open access malaria box. PLoS neglected tropical diseases, Vol. 8, H. 1 , e2610.

Keiser, Jennifer and Vargas, Mireille and Rubbiani, Riccardo and Gasser, Gilles and Biot, Christophe. (2014) In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasites and Vectors, 7 (424).

Wang, Chunkai and Zhao, Qingjie and Min, Jaeki and Muniyan, Sakthivel and Vargas, Mireille and Wang, Xiaofang and Dong, Yuxiang and Guy, R. Kiplin and Lin, Ming-Fong and Keiser, Jennifer and Vennerstrom, Jonathan L.. (2014) Antischistosomal versus antiandrogenic properties of aryl hydantoin Ro 13-3978. American journal of tropical medicine and hygiene, Vol. 90, H. 6. pp. 1156-1158.

Spivak, Anna Yu and Keiser, Jennifer and Vargas, Mireille and Gubaidullin, Rinat R. and Nedopekina, Darya A. and Shakurova, Elvira R. and Khalitova, Rezeda R. and Odinokov, Victor N.. (2014) Synthesis and activity of new triphenylphosphonium derivatives of betulin and betulinic acid against Schistosoma mansoni in vitro and in vivo. Bioorganic & medicinal chemistry, 22 (21). pp. 6297-6304.

2013

Keiser, J. and Tritten, L. and Silbereisen, A. and Speich, B. and Adelfio, R. and Vargas, M.. (2013) Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2119.

Ingram, Katrin and Duthaler, Urs and Vargas, Mireille and Ellis, William and Keiser, Jennifer. (2013) Disposition of mefloquine and enpiroline is highly influenced by a chronic Schistosoma mansoni infection. Antimicrobial agents and chemotherapy, Vol. 57, H. 9. pp. 4506-4511.

Tritten, Lucienne and Keiser, Jennifer and Godejohann, Markus and Utzinger, Jürg and Vargas, Mireille and Beckonert, Olaf and Holmes, Elaine and Saric, Jasmina. (2013) Metabolic profiling framework for discovery of candidate diagnostic markers of malaria. Scientific Reports, 3. p. 2769.