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Items where contributor is "Pluschke, Gerd"

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2017

Owusu, Enid and Newman, Mercy J. and Akumwena, Amos and Bannerman, Elizabeth and Pluschke, Gerd. (2017) Evaluating decontamination protocols for the isolation of Mycobacterium ulcerans from swabs. BMC microbiology, 17. p. 2.

Cornick, Jennifer E. and Tastan Bishop, Özlem and Yalcin, Feyruz and Kiran, Anmol M. and Kumwenda, Benjamin and Chaguza, Chrispin and Govindpershad, Shanil and Ousmane, Sani and Senghore, Madikay and du Plessis, Mignon and Pluschke, Gerd and Ebruke, Chinelo and McGee, Lesley and Sigaùque, Beutel and Collard, Jean-Marc and Bentley, Stephen D. and Kadioglu, Aras and Antonio, Martin and von Gottberg, Anne and French, Neil and Klugman, Keith P. and Heyderman, Robert S. and Alderson, Mark and Everett, Dean B. and PAGe consortium, . (2017) The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1. Vaccine, 35 (6). pp. 972-980.

Addison, Naa Okaikor and Pfau, Stefanie and Koka, Eric and Aboagye, Samuel Yaw and Kpeli, Grace and Pluschke, Gerd and Yeboah-Manu, Dorothy and Junghanss, Thomas. (2017) Assessing and managing wounds of Buruli ulcer patients at the primary and secondary health care levels in Ghana. PLoS Neglected Tropical Diseases, 11 (2). e0005331.

Kpeli, Grace and Buultjens, Andrew H. and Giulieri, Stefano and Owusu-Mireku, Evelyn and Aboagye, Samuel Y. and Baines, Sarah L. and Seemann, Torsten and Bulach, Dieter and Gonçalves da Silva, Anders and Monk, Ian R. and Howden, Benjamin P. and Pluschke, Gerd and Yeboah-Manu, Dorothy and Stinear, Timothy. (2017) Genomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in Ghana. PeerJ, 5. e3047.

Favuzza, Paola and Guffart, Elena and Tamborrini, Marco and Scherer, Bianca and Dreyer, Anita M. and Rufer, Arne C. and Erny, Johannes and Hoernschemeyer, Joerg and Thoma, Ralf and Schmid, Georg and Gsell, Bernard and Lamelas, Araceli and Benz, Joerg and Joseph, Catherine and Matile, Hugues and Pluschke, Gerd and Rudolph, Markus G.. (2017) Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody. eLife, 6. e20383.

Bieri, Raphael and Scherr, Nicole and Ruf, Marie-Thérèse and Dangy, Jean-Pierre and Gersbach, Philipp and Gehringer, Matthias and Altmann, Karl-Heinz and Pluschke, Gerd. (2017) The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR. ACS chemical biology, 12 (5). pp. 1297-1307.

Ruf, Marie-Thérèse and Andreoli, Arianna and Vujic, Gabriel and Itin, Peter and Pluschke, Gerd and Schmid, Peter. (2017) Exudate collection using wound sponges - An easy, non-invasive and reliable method to explore protease activities in ulcers. Wound Repair and Regeneration, 25 (2). pp. 320-326.

N'krumah, Raymond T. A. S. and Koné, Brama and Cissé, Guéladio and Tanner, Marcel and Utzinger, Jürg and Pluschke, Gerd and Tiembré, Issaka. (2017) Characteristics and epidemiological profile of Buruli ulcer in the district of Tiassalé, south Côte d'Ivoire. Acta Tropica, 175. pp. 138-144.

2016

Ampah, Kobina Assan and Nickel, Beatrice and Asare, Prince and Ross, Amanda and De-Graft, Daniel and Kerber, Sarah and Spallek, Ralf and Singh, Mahavir and Pluschke, Gerd and Yeboah-Manu, Dorothy and Röltgen, Katharina. (2016) A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans. PLoS neglected tropical diseases, 10 (1). e0004387.

Vogel, Moritz and Bayi, Pierre F. and Ruf, Marie-Thérèse and Bratschi, Martin W. and Bolz, Miriam and Um Boock, Alphonse and Zwahlen, Marcel and Pluschke, Gerd and Junghanss, Thomas. (2016) Local heat application for the treatment of Buruli ulcer : results of a phase II open label single center non comparative clinical trial. Clinical Infectious Diseases, 62 (3). pp. 342-350.

N'krumah, Raymond T. A. S. and Koné, Brama and Tiembre, Issaka and Cissé, Guéladio and Pluschke, Gerd and Tanner, Marcel and Utzinger, Jürg. (2016) Socio-environmental factors associated with the risk of contracting Buruli ulcer in Tiassalé, South Côte d'Ivoire : a case-control study. PLoS neglected tropical diseases, 10 (1). e0004327.

Bieri, Raphael and Bolz, Miriam and Ruf, Marie-Thérèse and Pluschke, Gerd. (2016) Interferon-γ is a crucial activator of early host immune defense against Mycobacterium ulcerans infection in mice. PLoS neglected tropical diseases, 10 (2). e0004450.

Bolz, Miriam and Bénard, Angèle and Dreyer, Anita M. and Kerber, Sarah and Vettiger, Andrea and Oehlmann, Wulf and Singh, Mahavir and Duthie, Malcolm S. and Pluschke, Gerd. (2016) Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer. PLoS neglected tropical diseases, 10 (2). e0004431.

Tabah, Earnest Njih and Nsagha, Dickson Shey and Bissek, Anne-Cécile Zoung-Kanyi and Njamnshi, Alfred Kongnyu and Bratschi, Martin W. and Pluschke, Gerd and Um Boock, Alphonse. (2016) Buruli ulcer in Cameroon: the development and impact of the National Control Programme. PLoS neglected tropical diseases, 10 (1). e0004224.

Favuzza, Paola and Blaser, Simon and Dreyer, Anita M. and Riccio, Guy and Tamborrini, Marco and Thoma, Ralf and Matile, Hugues and Pluschke, Gerd. (2016) Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA. Malaria journal, 15. p. 161.

Ampah, Kobina Assan and Asare, Prince and Binnah, Daniel De-Graft and Maccaulley, Samuel and Opare, William and Röltgen, Katharina and Pluschke, Gerd and Yeboah-Manu, Dorothy. (2016) Burden and historical trend of Buruli Ulcer prevalence in selected communities along the Offin River of Ghana. PLoS neglected tropical diseases, 10 (4). e0004603.

Scherr, Nicole and Pluschke, Gerd and Panda, Manoranjan. (2016) Comparative study of activities of a diverse set of antimycobacterial agents against Mycobacterium tuberculosis and Mycobacterium ulcerans. Antimicrobial agents and chemotherapy, 60 (5). pp. 3132-3137.

Ampah, Kobina Assan and Pinho-Nascimento, Carlos Augusto and Kerber, Sarah and Asare, Prince and De-Graft, Daniel and Adu-Nti, Frank and Paixão, Izabel C. N. P. and Niel, Christian and Yeboah-Manu, Dorothy and Pluschke, Gerd and Röltgen, Katharina. (2016) Limited genetic diversity of Hepatitis b virus in the general population of the offin river valley in Ghana. PLoS one, 11 (6). e0156864.

Ruf, Marie-Thérèse and Bolz, Miriam and Vogel, Moritz and Bayi, Pierre F. and Bratschi, Martin W. and Sopho, Ghislain Emmanuel and Yeboah-Manu, Dorothy and Um Boock, Alphonse and Junghanss, Thomas and Pluschke, Gerd. (2016) Spatial distribution of Mycobacterium ulcerans in Buruli ulcer lesions: implications for laboratory diagnosis. PLoS Neglected Tropical Diseases, 10 (6). e0004767.

Lamelas, Araceli and Ampah, Kobina Assan and Aboagye, Samuel and Kerber, Sarah and Danso, Emelia and Asante-Poku, Adwoa and Asare, Prince and Parkhill, Julian and Harris, Simon R. and Pluschke, Gerd and Yeboah-Manu, Dorothy and Röltgen, Katharina. (2016) Spatiotemporal co-existence of two Mycobacterium ulcerans clonal complexes in the Offin River Valley of Ghana. PLoS Neglected Tropical Diseases, 10 (7). e0004856.

Kpeli, G. and Darko Otchere, I. and Lamelas, A. and Buultjens, A. L. and Bulach, D. and Baines, S. L. and Seemann, T. and Giulieri, S. and Nakobu, Z. and Aboagye, S. Y. and Owusu-Mireku, E. and Pluschke, G. and Stinear, T. P. and Yeboah-Manu, D.. (2016) Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana. New microbes and new infections, 13. pp. 92-101.

Dangy, Jean-Pierre and Scherr, Nicole and Gersbach, Philipp and Hug, Melanie N. and Bieri, Raphael and Bomio, Claudio and Li, Jun and Huber, Sylwia and Altmann, Karl-Heinz and Pluschke, Gerd. (2016) Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 10 (6). e0004808.

Tabah, Earnest Njih and Nsagha, Dickson Shey and Bissek, Anne-Cecile Zoung-Kanyi and Bratschi, Martin W. and Njamnshi, Theophilus Ngeh and Plushke, Gerd and Njamnshi, Alfred Kongnyu. (2016) The burden of leprosy in Cameroon: fifteen years into the post-elimination era. PLoS Neglected Tropical Diseases, 10 (10). e0005012.

Bénard, Angèle and Sala, Claudia and Pluschke, Gerd. (2016) Mycobacterium ulcerans mouse model refinement for pre-clinical profiling of vaccine candidates. PLoS one, 11 (11). e0167059.

Rose, Natalie and Pinho-Nascimento, Carlos Augusto and Ruggieri, Alessia and Favuzza, Paola and Tamborrini, Marco and Roth, Hanna and Baroni de Moraes, Marcia Terezinha and Matile, Hugues and Jänisch, Thomas and Pluschke, Gerd and Röltgen, Katharina. (2016) Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization. BMC biotechnology, 16. p. 83.

Chaguza, Chrispin and Cornick, Jennifer E. and Harris, Simon R. and Andam, Cheryl P. and Bricio-Moreno, Laura and Yang, Marie and Yalcin, Feyruz and Ousmane, Sani and Govindpersad, Shanil and Senghore, Madikay and Ebruke, Chinelo and Du Plessis, Mignon and Kiran, Anmol M. and Pluschke, Gerd and Sigauque, Betuel and McGee, Lesley and Klugman, Keith P. and Turner, Paul and Corander, Jukka and Parkhill, Julian and Collard, Jean-Marc and Antonio, Martin and von Gottberg, Anne and Heyderman, Robert S. and French, Neil and Kadioglu, Aras and Hanage, William P. and Everett, Dean B. and Bentley, Stephen D. and PAGe Consortium, . (2016) Understanding pneumococcal serotype 1 biology through population genomic analysis. BMC infectious diseases, 16. p. 649.

2015

Dreyer, Anita and Röltgen, Katharina and Dangy, Jean Pierre and Ruf, Marie Thérèse and Scherr, Nicole and Bolz, Miriam and Tobias, Nicholas Jay and Moes, Charles and Vettiger, Andrea and Stinear, Timothy Paul and Pluschke, Gerd. (2015) Identification of the Mycobacterium ulcerans protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer. PLoS neglected tropical diseases, Vol. 9, H. 2 , e0003477.

Walker, Karen M. and Okitsu, Shinji and Porter, David W. and Duncan, Christopher and Amacker, Mario and Pluschke, Gerd and Cavanagh, David R. and Hill, Adrian V. S. and Todryk, Stephen M.. (2015) Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships. Immunology, Vol. 145, H. 1. S. 71-81.

Andreoli, A. and Ruf, M. T. and Itin, P. and Pluschke, G. and Schmid, P.. (2015) Phosphorylation of the ribosomal protein S6, a marker of mTOR (mammalian target of rapamycin) pathway activation, is strongly increased in hypertrophic scars and keloids. British journal of dermatology, Vol. 172, H. 5. S. 1415-1417.

Bolz, Miriam and Bratschi, Martin W. and Kerber, Sarah and Minyem, Jacques C. and Um Boock, Alphonse and Vogel, Moritz and Bayi, Pierre Franklin and Junghanss, Thomas and Brites, Daniela and Harris, Simon R. and Parkhill, Julian and Pluschke, Gerd and Lamelas Cabello, Araceli. (2015) Locally confined clonal complexes of Mycobacterium ulcerans in two Buruli ulcer endemic regions of Cameroon. PLoS neglected tropical diseases, Vol. 9, H. 6 , e0003802.

Ogbechi, Joy and Ruf, Marie-Thérèse and Hall, Belinda S. and Bodman-Smith, Katherine and Vogel, Moritz and Wu, Hua-Lin and Stainer, Alexander and Esmon, Charles T. and Ahnström, Josefin and Pluschke, Gerd and Simmonds, Rachel E.. (2015) Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions. PLoS Pathogens, Vol. 11, H. 7 , e1005011.

Bolz, Miriam and Kerber, Sarah and Zimmer, Gert and Pluschke, Gerd. (2015) Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease. PLoS neglected tropical diseases, Vol. 9, H. 8 , e0004011.

Scherr, Nicole and Pluschke, Gerd and Thompson, Charles J. and Ramón-García, Santiago. (2015) Selamectin is the avermectin with the best potential for Buruli ulcer treatment. PLoS neglected tropical diseases, Vol. 9, H. 8 , e0003996.

Silbereisen, Angelika and Tamborrini, Marco and Wittwer, Matthias and Schürch, Nadia and Pluschke, Gerd. (2015) Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species. BMC microbiology, 15. p. 198.

Tuffour, Joseph and Owusu-Mireku, Evelyn and Ruf, Marie-Therese and Aboagye, Samuel and Kpeli, Grace and Akuoku, Victor and Pereko, Janet and Paintsil, Albert and Bonney, Kofi and Ampofo, William and Pluschke, Gerd and Yeboah-Manu, Dorothy. (2015) Challenges associated with management of Buruli ulcer/human immunodeficiency virus coinfection in a treatment center in Ghana : a case series study. American journal of tropical medicine and hygiene, 93 (2). pp. 216-223.

Tamborrini, Marco and Geib, Nina and Marrero-Nodarse, Aniebrys and Jud, Maja and Hauser, Julia and Aho, Celestine and Lamelas, Araceli and Zuniga, Armando and Pluschke, Gerd and Ghasparian, Arin and Robinson, John A.. (2015) A synthetic virus-like particle streptococcal vaccine candidate using B-cell epitopes from the proline-rich region of pneumococcal surface protein A. Vaccines, 3 (4). pp. 850-874.

Andreoli, Arianna and Mou, Ferdinand and Minyem, Jacques C. and Wantong, Fidèle G. and Noumen, Djeunga and Awah, Paschal K. and Pluschke, Gerd and Boock, Alphonse Um and Bratschi, Martin W.. (2015) Complete healing of a laboratory-confirmed Buruli ulcer lesion after receiving only herbal household remedies. PLoS neglected tropical diseases, 9 (11). e0004102.

Sater, Mohamad R. Abdul and Lamelas, Araceli and Wang, Guilin and Clark, Tyson A. and Röltgen, Katharina and Mane, Shrikant and Korlach, Jonas and Pluschke, Gerd and Schmid, Christoph D.. (2015) DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates. PLoS one, 10 (12). e0144612.

Owusu, E. and Newman, M. J. and Akumwena, A. and Pfosu-Appiah, L. and Pluschke, G.. (2015) Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana. International journal of mycobacteriology, 4 (3). pp. 184-190.

Röltgen, K. and Pluschke, G.. (2015) Epidemiology and disease burden of Buruli ulcer : a review. Research and Reports in Tropical Medicine, 6. pp. 59-73.

Cornick, J. E. and Chaguza, C. and Harris, S. R. and Yalcin, F. and Senghore, M. and Kiran, A. M. and Govindpershad, S. and Ousmane, S. and du Plessis, M. and Pluschke, G. and Ebruke, C. and McGee, L. and Sigauque, B. and Collard, J. M. and Antonio, M. and von Gottberg, A. and French, N. and Klugman, K. P. and Heyderman, R. S. and Bentley, S. D. and Everett, D. B.. (2015) Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae. Microbial genomics, 1 (2). pp. 1-13.

Röltgen, K. and Pluschke, G.. (2015) Mycobacterium ulcerans disease (Buruli ulcer): potential reservoirs and vectors. Current clinical microbiology reports, 2. pp. 35-43.

2014

Röltgen, Katharina and Bratschi, Martin W. and Ross, Amanda and Aboagye, Samuel Y. and Ampah, Kobina A. and Bolz, Miriam and Andreoli, Arianna and Pritchard, James and Minyem, Jacques C. and Noumen, Djeunga and Koka, Eric and Um Boock, Alphonse and Yeboah-Manu, Dorothy and Pluschke, Gerd. (2014) Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children. PLoS neglected tropical diseases, Vol. 8, H. 5 , e2904.

Bratschi, Martin W. and Ruf, Marie-Thérèse and Andreoli, Arianna and Minyem, Jacques C. and Kerber, Sarah and Wantong, Fidèle G. and Pritchard, James and Chakwera, Victoria and Beuret, Christian and Wittwer, Matthias and Noumen, Djeunga and Schürch, Nadia and Um Book, Alphonse and Pluschke, Gerd. (2014) Mycobacterium ulcerans persistence at a village water source of Buruli ulcer patients. PLoS neglected tropical diseases, Vol. 8, H. 3 , e2756.

Koeberling, Oliver and Ispasanie, Emma and Hauser, Julia and Rossi, Omar and Pluschke, Gerd and Caugant, Dominique A. and Saul, Allan and Maclennan, Calman A.. (2014) A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on Generalized Modules for Membrane Antigens (GMMA). Vaccine, 32 (23). pp. 2688-2695.

Junghanss, T. and Johnson, R. C. and Pluschke, G.. (2014) Mycobacterium ulcerans disease. In: Manson's tropical diseases. - 23rd ed.. [Edinburgh], S. 519-531.

Andreoli, Arianna and Ruf, Marie-Thérèse and Sopoh, Ghislain Emmanuel and Schmid, Peter and Pluschke, Gerd. (2014) Immunohistochemical monitoring of wound healing in antibiotic treated buruli ulcer patients. PLoS neglected tropical diseases, Vol. 8, H. 4 , e2809.

Bolz, Miriam and Ruggli, Nicolas and Ruf, Marie-Thérèse and Ricklin, Meret E. and Zimmer, Gert and Pluschke, Gerd. (2014) Experimental infection of the pig with Mycobacterium ulcerans : a novel model for studying the pathogenesis of Buruli ulcer disease. PLoS neglected tropical diseases, Vol. 8, H. 7 , e2968.

Vettiger, A. and Scherr, N. and Ruf, M. T. and Röltgen, K. and Pluschke, G.. (2014) Localization of mycobacterial antigens by immunofluorescence staining of agarose embedded cells. Mycobacterial diseases, Vol. 4, H. 3. S. 3-4.

Bratschi, Martin W. and Bolz, Miriam and Grize, Leticia and Kerber, Sarah and Minyem, Jacques C. and Um Boock, Alphonse and Yeboah-Manu, Dorothy and Ruf, Marie-Thérèse and Pluschke, Gerd. (2014) Primary cultivation : factors affecting contamination and Mycobacterium ulcerans growth after long turnover time of clinical specimens. BMC infectious diseases, Vol. 14 , 636.

Lamelas, Araceli and Harris, Simon R. and Röltgen, Katharina and Dangy, Jean-Pierre and Hauser, Julia and Kingsley, Robert A. and Connor, Thomas R. and Sie, Ali and Hodgson, Abraham and Dougan, Gordon and Parkhill, Julian and Bentley, Stephen D. and Pluschke, Gerd. (2014) Emergence of a new epidemic Neisseria meningitidis serogroup A clone in the African meningitis belt : high-resolution picture of genomic changes that mediate immune evasion. mBio, Vol. 5, H. 5 , e01974-14.

Hilty, Markus and Wüthrich, Daniel and Salter, Susannah J. and Engel, Hansjürg and Campbell, Samuel and Sá-Leão, Raquel and de Lencastre, Hermínia and Hermans, Peter and Sadowy, Ewa and Turner, Paul and Chewapreecha, Claire and Diggle, Mathew and Pluschke, Gerd and McGee, Lesley and Köseoğlu Eser, Özgen and Low, Donald E. and Smith-Vaughan, Heidi and Endimiani, Andrea and Küffer, Marianne and Dupasquier, Mélanie and Beaudoing, Emmanuel and Weber, Johann and Bruggmann, Rémy and Hanage, William P. and Parkhill, Julian and Hathaway, Lucy J. and Mühlemann, Kathrin and Bentley, Stephen D.. (2014) Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages. Genome biology and evolution, Vol. 6, H. 12. S. 3281-3294.

Ruf, M. T. and Andreoli, A. and Itin, P. and Pluschke, G. and Schmid, P.. (2014) Ribosomal protein S6 is hyperactivated and differentially phosphorylated in epidermal lesions of patients with psoriasis and atopic dermatitis. British journal of dermatology, Vol. 171, H. 6. S. 1533-1536.

Ispasanie, Emma and Pluschke, Gerd and Hodgson, Abraham and Sie, Ali and MacLennan, Calman and Koeberling, Oliver. (2014) Characterization of vaccine antigens of meningococcal serogroup W isolates from Ghana and Burkina Faso from 2003 to 2009. Faculty of 1000, Vol. 3. S. 264.

2013

Bratschi, Martin W. and Bolz, Miriam and Minyem, Jacques C. and Grize, Leticia and Wantong, Fidèle G. and Kerber, Sarah and Njih Tabah, Earnest and Ruf, Marie-Thérèse and Mou, Ferdinand and Noumen, Djeunga and Um Boock, Alphonse and Pluschke, Gerd. (2013) Geographic distribution, age pattern and sites of lesions in a cohort of buruli ulcer patients from the mapé basin of cameroon. PLoS neglected tropical diseases, Vol. 7, H. 6 , e2252.

Herrmann, Mathias and Abdullah, Salim and Alabi, Abraham and Alonso, Pedro and Friedrich, Alexander W. and Fuhr, Günther and Germann, Anja and Kern, Winfried V. and Kremsner, Peter G. and Mandomando, Inacio and Mellmann, Alexander C. and Pluschke, Gerd and Rieg, Siegbert and Ruffing, Ulla and Schaumburg, Frieder and Tanner, Marcel and Peters, Georg and von Briesen, Hagen and von Eiff, Christof and von Müller, Lutz and Grobusch, Martin P.. (2013) Staphylococcal disease in Africa : another neglected 'tropical' disease. Future microbiology, Vol. 8. S. 17-26.

Yeboah-Manu, Dorothy and Kpeli, Grace S. and Ruf, Marie-Thérèse and Asan-Ampah, Kobina and Quenin-Fosu, Kwabena and Owusu-Mireku, Evelyn and Paintsil, Albert and Lamptey, Isaac and Anku, Benjamin and Kwakye-Maclean, Cynthia and Newman, Mercy and Pluschke, Gerd. (2013) Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin. PLoS neglected tropical diseases, Vol. 7, H. 5 , e2191.

Scherr, Nicole and Gersbach, Philipp and Dangy, Jean-Pierre and Bomio, Claudio and Li, Jun and Altmann, Karl-Heinz and Pluschke, Gerd. (2013) Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 7, H. 3 , e2143.

Huber, Charlotte A. and Pflüger, Valentin and Hamid, Abdul-Wahab M. and Forgor, Abudulai A. and Hodgson, Abraham and Sié, Ali and Junghanss, Thomas and Pluschke, Gerd. (2013) Lack of antigenic diversification of major outer membrane proteins during clonal waves of Neisseria meningitidis serogroup A colonization and disease. Pathogens and disease, Vol. 67. S. 4-10.

Grandgirard, D. and Gäumann, R. and Coulibaly, B. and Dangy, J. P. and Sie, A. and Junghanss, T. and Schudel, H. and Pluschke, G. and Leib, S. L.. (2013) The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, ID 312476.

Micoli, Francesca and Romano, Maria Rosaria and Tontini, Marta and Cappelletti, Emilia and Gavini, Massimiliano and Proietti, Daniela and Rondini, Simona and Swennen, Erwin and Santini, Laura and Filippini, Sara and Balocchi, Cristiana and Adamo, Roberto and Pluschke, Gerd and Norheim, Gunnstein and Pollard, Andrew and Saul, Allan and Rappuoli, Rino and Maclennan, Calman A. and Berti, Francesco and Costantino, Paolo. (2013) Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X. Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, H. 47. S. 19077-19082.

Altmann, Danny and Aseffa, Abraham and Bash, Margaret and Basta, Nicole and Borrow, Ray and Broome, Claire and Caugant, Dominique and Clark, Tom and Collard, Jean-Marc and Djingarey, Mamoudou and Goldblatt, David and Greenwood, Brian and Griffiths, Ulla and Hajjeh, Rana and Hassan-King, Musa and Hugonnet, Stephane and Kimball, Ann Marie and LaForce, Marc and MacLennan, Calman and Maiden, Martin C. J. and Manigart, Olivier and Mayer, Leonard and Messonnier, Nancy and Moisi, Jennifer and Moore, Katie and Moto, Daugla Doumagoum and Mueller, Judith and Nascimento, Maria and Obaro, Stephen and Ouedraogo, Rasmata and Page, Anne-Laure and Perea, Willima and Pluschke, Gerd and Preziosi, Mari-Pierre and Sow, Samba and Stephens, David and Stuart, James and Thomson, Madeleiene and Tiendrebeogo, Sylvestre and Trape, Jean-Francois and Vernet, Guy. (2013) Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt. Vaccine : the official journal of the International Society for Vaccines, 31 (11). pp. 1453-1457.

2012

Ruf, M. T. and Schütte, D. and Chauffour, A. and Jarlier, V. and Ji, B. and Pluschke, G.. (2012) Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model. Antimicrobial agents and chemotherapy : AAC, Vol. 56, H. 2. S. 687-696.

Käser, M. and Hauser, J. and Pluschke, G.. (2012) PCR typing of Mycobacterium ulcerans lineages based on large sequence polymorphisms. Journal of medical microbiology and diagnosis, Vol. S1 , 001.

Berti, F. and Romano, M. R. and Micoli, F. and Pinto, V. and Cappelletti, E. and Gavini, M. and Proietti, D. and Pluschke, G. and MacLennan, C. A. and Costantino, P.. (2012) Relative stability of meningococcal serogroup A and X polysaccharides. Vaccine : the official journal of the International Society for Vaccines, 30. pp. 6409-6415.

Bauer, M. and Chicca, A. and Tamborrini, M. and Eisen, D. and Lerner, R. and Lutz, B. and Poetz, O. and Pluschke, G. and Gertsch, J.. (2012) Identification and qualification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors. Journal of biological chemistry, Vol. 287, H. 44. S. 36944-36967.

Röltgen, K. and Stinear, T. P. and Pluschke, G.. (2012) The genome, evolution and diversity of Mycobacterium ulcerans. Infection, genetics and evolution, Vol. 12, H. 3. S. 522-529.

Röltgen, K. and Assan-Ampah, K. and Danso, E. and Yeboah-Manu, D. and Pluschke, G.. (2012) Development of a temperature-switch PCR-based SNP typing method for Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 6, H. 11 , e1904.

Yeboah-Manu, D. and Röltgen, K. and Opare, W. and Asan-Ampah, K. and Quenin-Fosu, K. and Asante-Poku, A. and Ampadu, E. and Fyfe, J. and Koram, K. and Ahorlu, C. and Pluschke, G.. (2012) Sero-epidemiology as a tool to screen populations for exposure to Mycobacterium ulcerans. PLoS neglected tropical diseases, Vol. 6, H. 1 , e1460.

Khan, M. G. and Bhaskar, K. R. and Salam, M. A. and Akther, T. and Pluschke, G. and Mondal, D.. (2012) Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for detection of Leishmania DNA in buffy coat from visceral leishmaniasis patients. Parasites and Vectors, 5 (280).

Doig, K. D. and Holt, K. E. and Fyfe, J. A. and Lavender, C. J. and Eddyani, M. and Portaels, F. and Yeboah-Manu, D. and Pluschke, G. and Seemann, T. and Stinear, T. P.. (2012) On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer. BMC genomics, Vol. 13 , 257.

Scherr, N. and Röltgen, K. and Witschel, M. and Pluschke, G.. (2012) Screening of antifungal azole drugs and agrochemicals with an adapted Alamar Blue-based assay demonstrates antibacterial activity of Croconazole against Mycobacterium ulcerans. Antimicrobial agents and chemotherapy, Vol. 56, H. 12. S. 6410-6413.

Pluschke, Gerd and Tamborrini, Marco. (2012) Development of a virosomal malaria vaccine candidate : from synthetic peptide design to clinical concept validation. Future virology, Vol. 7, H. 8. S. 779-790.

Bratschi, M. W. and Njih, Tabah and Bolz, M. and Stucki, D. and Borrell, S. and Gagneux, S. and Noumen-Djeunga, B. and Junghanss, T. and Um Boock, A. and Pluschke, G.. (2012) A case of cutaneous tuberculosis in a Buruli ulcer-endemic area. PLoS neglected tropical diseases, Vol. 6, H. 8 , e1751.

Dreyer, A. M. and Matile, H. and Papastogiannidis, P. and Kamber, J. and Favuzza, P. and Voss, T. S. and Wittlin, S. and Pluschke, G.. (2012) Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen. Journal of immunology : official journal of the American Association of Immunologists, Vol. 188, H. 12. S. 6225-6237.

2011

Cech, Patrick Georges and Aebi, Thomas and Abdallah, Mwanajaa Shomari and Mpina, Maxmillian and Machunda, Ester Barnabas and Westerfeld, Nicole and Stoffel, Sabine Alexandra and Zurbriggen, Rinaldo and Pluschke, Gerd and Tanner, Marcel and Daubenberger, Claudia and Genton, Blaise and Abdulla, Salim. (2011) Virosome-formulated Plasmodium falciparum AMA-1 & CSP derived peptides as malaria vaccine : randomized phase 1b trial in semi-immune adults & children. PLoS one, Vol. 6, H. 7 , e22273.

Yeboah-Manu D., and Danso, E. and Ampah, K. and Asante-Poku A., and Nakobu, Z. and Pluschke, G.. (2011) Isolation of mycobacterium ulcerans from swab and fine-needle-aspiration specimens. Journal of clinical microbiology, Vol. 49, H. 5. S. 1997-1999.

Ruf, M. T. and Sopoh, G. E. and Brun, L. V. and Dossou, A. D. and Barogui, Y. T. and Johnson, R. C. and Pluschke, G.. (2011) Histopathological changes and clinical responses of Buruli ulcer plaque lesions during chemotherapy : a role for surgical removal of necrotic tissue? PLoS neglected tropical diseases, Vol. 5, H. 9 , e1334.

Yeboah-Manu D., and Asante-Poku A., and Bodmer, T. and Stucki, D. and Koram, K. and Bonsu, F. and Pluschke, G. and Gagneux, S.. (2011) Genotypic diversity and drug susceptibility patterns among M. tuberculosis complex isolates from South-Western Ghana. PLoS one, Vol. 6, H. 7 , e21906.

Gersbach, P. and Jantsch, A. and Feyen, F. and Scherr, N. and Dangy, J. P. and Pluschke, G. and Altmann, K. H.. (2011) A ring-closing metathesis (RCM)-based approach to mycolactones A/B. Chemistry : a European journal, Vol. 17, H. 46. S. 13017-13031.

Chauty, A. and Ardant, M. F. and Marsollier, L. and Pluschke, G. and Landier, J. and Adeye, A. and Goundoté, A. and Cottin, J. and Ladikpo, T. and Ruf, T. and Ji, B.. (2011) Oral treatment for Mycobacterium ulcerans infection : results from a pilot study in Benin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 52, H. 1. S. 94-96.

Ruf, M. T. and Chauty, A. and Adeye, A. and Ardant, M. F. and Koussemou, H. and Johnson, R. C. and Pluschke, G.. (2011) Secondary Buruli ulcer skin lesions emerging several months after completion of chemotherapy : paradoxical reaction or evidence for immune protection? PLoS neglected tropical diseases, Vol. 5, H. 8 , e1252.

Yeboah-Manu D., and Asante-Poku A., and Asan-Ampah K., and Ampadu, E. D. and Pluschke, G.. (2011) Combining PCR with microscopy to reduce costs of laboratory diagnosis of Buruli ulcer. American journal of tropical medicine and hygiene, Vol. 85, H. 5. S. 900-904.

Tamborrini, M. and Stoffel, S. A. and Westerfeld, N. and Amacker, M. and Theisen, M. and Zurbriggen, R. and Pluschke, G.. (2011) Immunogenicity of a virosomally-formulated Plasmodium falciparum GLURP-MSP3 chimeric protein-based malaria vaccine candidate in comparison to adjuvanted formulations. Malaria journal, Vol. 10 , 359.

Ghasparian, A. and Riedel, T. and Koomullil, J. and Moehle, K. and Gorba, C. and Svergun, D. I. and Perriman, A. W. and Mann, S. and Tamborrini, M. and Pluschke, G. and Robinson, J. A.. (2011) Engineered synthetic virus-like particles and their use in vaccine delivery. ChemBioChem : a European journal of chemical biology, Vol. 12, H. 1. S. 100-109.

Tamborrini, M. and Bauer, M. and Bolz, M. and Maho, A. and Oberli, M. A. and Werz, D. B. and Schelling, E. and Zinsstag, J. and Seeberger, P. H. and Frey, J. and Pluschke, G.. (2011) Identification of an African bacillus anthracis lineage that lacks expression of the spore surface associated anthrose containing oligosaccharide. Journal of bacteriology : a publication of the American Society for Microbiology, Vol. 193, H. 14. S. 3506-3511.

Röltgen, K. and Pluschke, G.. (2011) SNP-Typisierung des Buruli-Ulkus-Erregers. Biospektrum, Vol. 17, H. 1. S. 48-51.

2010

Tamborrini, M. and Liu, X. and Mugasa, J. P. and Kwon, Y. U. and Kamena, F. and Seeberger, P. H. and Pluschke, G.. (2010) Synthetic glycosylphosphatidylinositol microarray reveals differential antibody levels and fine specificities in children with mild and severe malaria. Bioorganic & medicinal chemistry letters : a Tetrahedron publication for the rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Vol. 18. S. 3747-3752.

Käser, M. and Ruf, M. T. and Hauser, J. and Pluschke, G.. (2010) Optimized DNA preparation from mycobacteria. Cold Spring Harbor protocols, Vol. 2010, H. 4 , pdb.prot5408.

Röltgen, K. and Qi, W. and Ruf, M. T. and Mensah-Quainoo E., and Pidot, S. J. and Seemann, T. and Stinear, T. P. and Käser, M. and Yeboah-Manu D., and Pluschke, G.. (2010) Single nucleotide polymorphism typing of Mycobacterium ulcerans reveals focal transmission of Buruli ulcer in a highly endemic region of Ghana. PLoS neglected tropical diseases, Vol. 4, H. 7 , e751.

Pluschke, Gerd and Tamborrini, Marco. (2010) Virosomal technology in malaria vaccine development. Future virology, Vol. 5, H. 3. S. 247-250.

Pidot, S. J. and Porter, J. L. and Marsollier, L. and Chauty, A. and Migot-Nabias F., and Badaut, C. and Benard, A. and Ruf, M. T. and Seemann, T. and Johnson, P. D. and Davies, J. K. and Jenkin, G. A. and Pluschke, G. and Stinear, T. P.. (2010) Serological evaluation of Mycobacterium ulcerans antigens identified by comparative genomics. PLoS neglected tropical diseases, Vol. 4, H. 11 , e872.

Dujardin, J. C. and Herrera, S. and do, R. and Arevalo, J. and Boelaert, M. and Carrasco, H. J. and Correa-Oliveira R., and Garcia, L. and Gotuzzo, E. and Gyorkos, T. W. and Kalergis, A. M. and Kouri, G. and Larraga, V. and Lutumba, P. and Macias Garcia M. A., and Manrique-Saide P. C., and Modabber, F. and Nieto, A. and Pluschke, G. and Robello, C. and Rojas de A. A., and Rumbo, M. and Santos Preciado J. I., and Sundar, S. and Torres, J. and Torrico, F. and Van der Stuyft P., and Victoir, K. and Olesen, O. F.. (2010) Research priorities for neglected infectious diseases in Latin America and the Caribbean region. PLoS neglected tropical diseases, Vol. 4, H. 10 , e780.

Dreyer, A. M. and Beauchamp, J. and Matile, H. and Pluschke, G.. (2010) An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells. BMC biotechnology, Vol. 10 , 87.

2009

Tamborrini, M. and Mueller, M. S. and Stoffel, S. A. and Westerfeld, N. and Vogel, D. and Boato, F. and Zurbriggen, R. and Robinson, J. A. and Pluschke, G.. (2009) Design and pre-clinical profiling of a Plasmodium falciparum MSP-3 derived component for a multi-valent virosomal malaria vaccine. Malaria Journal, Vol. 8 , 314.

Tamborrini, M. and Oberli, M. A. and Werz, D. B. and Schürch, N. and Frey, J. and Seeberger, P. H. and Pluschke, G.. (2009) Immuno-detection of anthrose containing tetrasaccharide in the exosporium of Bacillus anthracis and Bacillus cereus strains. Journal of applied microbiology, Vol. 106, H. 5. S. 1618-1628.

Käser, M. and Gutmann, O. and Hauser, J. and Stinear, T. and Cole, S. and Yeboah-Manu D., and Dernick, G. and Certa, U. and Pluschke, G.. (2009) Lack of insertional-deletional polymorphism in a collection of Mycobacterium ulcerans isolates from Ghanaian Buruli ulcer patients. Journal of clinical microbiology, Vol. 47, H. 11. S. 3640-3646.

Leimkugel, J. and Racloz, L. and Da Silva J., and Pluschke, G.. (2009) Global review of meningococcal disease : a shifting etiology. Journal of bacteriology research, Vol. 1, H. 1.

Huygen, K. and Adjei, O. and Affolabi, D. and Bretzel, G. and Demangel, C. and Fleischer, B. and Johnson, R. C. and Pedrosa, J. and Phanzu, D. M. and Phillips, R. O. and Pluschke, G. and Siegmund, V. and Singh, M. and van der Werf T. S., and Wansbrough-Jones M., and Portaels, F.. (2009) Buruli ulcer disease : prospects for a vaccine. Medical microbiology and immunology = Zeitschrift für medizinische Mikrobiologie und Immunologie, Vol. 198, H. 2. S. 69-77.

Junghanss, T. and Um Boock A., and Vogel, M. and Schütte, D. and Weinlaeder, H. and Pluschke, G.. (2009) Phase change material for thermotherapy of Buruli ulcer : a prospective observational single centre proof-of-principle trial. PLoS neglected tropical diseases, Vol. 3, H. 2 , e380.

Käser, M. and Hauser, J. and Pluschke, G.. (2009) Single nucleotide polymorphisms on the road to strain differentiation in Mycobacterium ulcerans. Journal of clinical microbiology, Vol. 47, H. 11. S. 3647-3652.

Schütte, D. and Um Boock A., and Pluschke, G.. (2009) Phagocytosis of Mycobacterium ulcerans in the course of rifampicin and streptomycin chemotherapy in Buruli ulcer lesions. British journal of dermatology, Vol. 160, H. 2. S. 273-283.

Braxmeier, S. and Hellmann, M. and Beck, A. and Umboock, A. and Pluschke, G. and Junghanss, T. and Weinlaeder, H.. (2009) Phase change material for thermotherapy of Buruli ulcer : modelling as an aid to implementation. Journal of medical engineering & technology : an international bi-monthly journal promoting the application of engineering and technology in medical research and clinical medicine, Vol. 33, H. 7. S. 559-566.

Käser, M. and Ruf, M. T. and Hauser, J. and Marsollier, L. and Pluschke, G.. (2009) Optimized method for preparation of DNA from pathogenic and environmental mycobacteria. Applied and environmental microbiology, Vol. 75, H. 2. S. 414-418.

Käser, M. and Hauser, J. and Small, P. and Pluschke, G.. (2009) Large sequence polymorphisms unveil the phylogenetic relationship of environmental and pathogenic mycobacteria related to Mycobacterium ulcerans. Applied and environmental microbiology, Vol. 75, H. 17. S. 5667-5675.

Qi, W. and Käser, M. and Röltgen, K. and Yeboah-Manu D., and Pluschke, G.. (2009) Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS Pathogens, Vol. 5, H. 9 , e1000580.

Schütte, Daniela and Pluschke, Gerd. (2009) Immunosuppression and treatment-associated inflammatory response in patients with Mycobacterium ulcerans infection (Buruli ulcer). Expert opinion on biological therapy, 9 (2). pp. 187-200.