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Items where contributor is "Oufir, Mouhssin"

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2020

Zabela, Volha and Sampath, Chethan and Oufir, Mouhssin and Butterweck, Veronika and Hamburger, Matthias. (2020) Single dose pharmacokinetics of intravenous 3,4-dihydroxyphenylacetic acid and 3-hydroxyphenylacetic acid in rats. Fitoterapia, 142. p. 104526.

Ehrsam, Daniel and Sieber, Sandro and Oufir, Mouhssin and Porta, Fabiola and Hamburger, Matthias and Huwyler, Jörg and Meyer zu Schwabedissen, Henriette E.. (2020) Design, Synthesis, and Characterization of a Paclitaxel Formulation Activated by Extracellular MMP9. Bioconjugate Chemistry, 31 (3). pp. 781-793.

2019

Weissenstein, Ulrike and Kunz, Matthias and Oufir, Mouhssin and Wang, Jue Theresa and Hamburger, Matthias and Urech, Konrad and Regueiro, Ursula and Baumgartner, S.. (2019) Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro. BMC complementary and alternative medicine, 19 (1). p. 23.

Oufir, Mouhssin and Zabela, Volha and Hettich, Timm and Schlotterbeck, Götz and Wimmer, Laurin and Mihovilovic, Marko D. and Guillet, Fabrice and Bouaita, Belkacem and Shevchenko, Bénédicte and Hamburger, Matthias. (2019) Piperine analogs as modulators of the central nervous system. Chimia, 73 (3). p. 206.

2018

Zabela, Volha and Hettich, Timm and Schlotterbeck, Götz and Wimmer, Laurin and Mihovilovic, Marko D. and Guillet, Fabrice and Bouaita, Belkacem and Shevchenko, Bénédicte and Hamburger, Matthias and Oufir, Mouhssin. (2018) GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding. Journal of Chromatography B, 1072. pp. 379-389.

Meyer zu Schwabedissen, Henriette E. and Ferreira, Celio and Schaefer, Anima M. and Oufir, Mouhssin and Seibert, Isabell and Hamburger, Matthias and Tirona, Rommel G.. (2018) Thyroid hormones are transport substrates and transcriptional regulators of Organic Anion Transporting Polypeptide 2B1. Molecular Pharmacology, 94 (1). pp. 700-712.

2017

Guccione, Clizia and Oufir, Mouhssin and Piazzini, Vieri and Eigenmann, Daniela Elisabeth and Jähne, Evelyn Andrea and Zabela, Volha and Faleschini, Maria Teresa and Bergonzi, Maria Camilla and Smiesko, Martin and Hamburger, Matthias and Bilia, Anna Rita. (2017) Andrographolide-loaded nanoparticles for brain delivery: formulation, charcterization and in vitro permeability using hCMEC/D3 cell line. European Journal of Pharmaceutics and Biopharmaceutics, 119. pp. 253-263.

2016

Jähne, Evelyn A. and Sampath, Chethan and Butterweck, Veronika and Hamburger, Matthias and Oufir, Mouhssin. (2016) Development and full validation of an UPLC-MS/MS method for the quantification of indirubin in rat plasma. Journal of Pharmaceutical and Biomedical Analysis, 128. pp. 247-252.

Moradi-Afrapoli, Fahimeh and Oufir, Mouhssin and Walter, Fruzsina R. and Deli, Maria A. and Smieško, Martin and Zabela, Volha and Butterweck, Veronika and Hamburger, Matthias. (2016) Validation of UHPLC-MS/MS methods for the determination of kaempferol and its metabolite 4-hydroxyphenyl acetic acid, and application to in vitro BBB and intestinal drug permeability studies. Journal of Pharmaceutical and Biomedical Analysis, 128. pp. 264-274.

Eigenmann, Daniela E. and Dürig, Carmen and Jähne, Evelyn A. and Smieško, Martin and Culot, Maxime and Gosselet, Fabien and Cecchelli, Romeo and Cederberg Helms, Hans Christian and Brodin, Birger and Wimmer, Laurin and Mihovilovic, Marko D. and Hamburger, Matthias and Oufir, Mouhssin. (2016) In vitro blood-brain barrier permeability predictions of piperine analogues with GABAA receptor modulating properties. European Journal of Pharmaceutics and Biopharmaceutics, 103. pp. 118-126.

Eigenmann, Daniela E. and Jähne, Evelyn A. and Smiesko, Martin and Hamburger, Matthias and Oufir, Mouhssin. (2016) Validation of an immortalized human (hBMEC) in vitro blood-brain barrier model. Analytical and Bioanalytical Chemistry, 408 (8). pp. 2095-2107.

Jähne, E. A. and Eigenmann, D. E. and Sampath, C. and Butterweck, V. and Culot, M. and Cecchelli, R. and Walter, F. R. and Deli, M. A. and Smiesko, M. and Hamburger, M. and Oufir, M.. (2016) Pharmacokinetics and in vitro blood-brain barrier screening of the plant-derived alkaloid tryptanthrin. Planta Medica, 82 (11-12). pp. 1021-1029.

Jähne, E. A. and Eigenmann, D. E. and Moradi-Afrapoli, F. and Verjee, S. and Butterweck, V. and Hebeisen, S. and Hettich, T. and Schlotterbeck, G. and Smiesko, M. and Hamburger, M. and Oufir, M.. (2016) Caco-2 permeability studies and hERG liability assessment of tryptanthrin and indolinone. Planta Medica, 82 (13). pp. 1192-1201.

Zabela, V. and Sampath, C. and Oufir, M. and Moradi-Afrapoli, F. and Butterweck, V. and Hamburger, M.. (2016) Pharmacokinetics and metabolism of dietary kaempferol and its metabolite 4-hydroxy-phenylacetic acid in rats. Fitoterapia, 115. pp. 189-197.

2015

Oufir, Mouhssin and Seiler, Christina and Gerodetti, Manon and Gerber, Julia and Fürer, Karin and Mennet-von Eiff, Monica and Elsas, Siegward-M. and Brenneisen, Rudolf and von Mandach, Ursula and Hamburger, Matthias and Potterat, Olivier. (2015) Quantification of burfadienolides in bryophyllum pinnatum leaves and manufactured products by UHPLC-ESIMS/MS. Planta Medica, 81 (12/13). pp. 1190-1197.

Witschel, Matthias C. and Rottmann, Matthias and Schwab, Anatol and Leartsakulpanich, Ubolsree and Chitnumsub, Penchit and Seet, Michael and Tonazzi, Sandro and Schwertz, Geoffrey and Stelzer, Frank and Mietzner, Thomas and McNamara, Case and Thater, Frank and Freymond, Céline and Jaruwat, Aritsara and Pinthong, Chatchadaporn and Riangrungroj, Pinpunya and Oufir, Mouhssin and Hamburger, Matthias and Mäser, Pascal and Sanz-Alonso, Laura M. and Charman, Susan and Wittlin, Sergio and Yuthavong, Yongyuth and Chaiyen, Pimchai and Diederich, François. (2015) Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT) : co-crystal structures of pyrazolopyrans with potent blood-and liver-stage activities. Journal of Medicinal Chemistry, 58 (7). pp. 3117-3130.

2014

Julianti, T. and Oufir, M. and Hamburger, M.. (2014) Quantification of the antiplasmodial alkaloid carpaine in papaya leaves (Carica papaya L.). Planta medica, Vol. 80, H. 13. pp. 1138-1142.

Schöffmann, A. and Wimmer, L. and Goldmann, D. and Khom, S. and Hintersteiner, J. and Baburin, I. and Schwarz, T. and Hintersteininger, M. and Pakfeifer, P. and Oufir, M. and Hamburger, M. and Erker, T. and Ecker, G. and Mihovilovic, M. and Hering, S.. (2014) Efficient modulation of of γ-aminobutyric acid type A (GABAA) receptors by piperine derivatives. Journal of Medicinal Chemistry, 57 (13). pp. 5602-5619.

Jähne, E. A. and Eigenmann, D. E. and Culot, M. and Cecchelli, R. and Walter, F. R. and Deli, M. A. and Tremmel, R. and Fricker, G. and Smiesko, M. and Hamburger, M. and Oufir, M.. (2014) Development and validation of an LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models. Journal of Pharmaceutical and Biomedical Analysis, 98. pp. 235-246.

2013

Zimmermann, Stefanie and Oufir, Mouhssin and Leroux, Alejandro and Krauth-Siegel, R. Luise and Becker, Katja and Kaiser, Marcel and Brun, Reto and Hamburger, Matthias and Adams, Michael. (2013) Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei. Bioorganic & medicinal chemistry, 21 (22). pp. 7202-7209.

Eigenmann, Daniela E. and Xue, Gongda and Kim, Kwang S. and Moses, Ashlee V. and Hamburger, Matthias and Oufir, Mouhssin. (2013) Comparative study of four immortalised human brain capillary endothelial cell lines, hCMEC/D3, hBMED, TY10, and BB19, and optimization of culture conditions, for an in vitro blood-brain barrier model for drug permeability studies. Fluids and Barriers of the CNS, 10 (33). pp. 1-6.

2012

Oufir, Mouhssin and Sampath, Chethan and Butterweck, Veronika and Hamburger, Matthias. (2012) Development and full validation of an UPLC-MS/MS method for the determination of an anti-allergic indolinone derivative in rat plasma, and application to a preliminary pharmacokinetic study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 902. pp. 27-34.