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Items where contributor is "De Libero, Gennaro"

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Consonni, Michela and Garavaglia, Claudio and Grilli, Andrea and de Lalla, Claudia and Mancino, Alessandra and Mori, Lucia and De Libero, Gennaro and Montagna, Daniela and Casucci, Monica and Serafini, Marta and Bonini, Chiara and Haussinger, Daniel and Ciceri, Fabio and Bernardi, Massimo and Mastaglio, Sara and Bicciato, Silvio and Dellabona, Paolo and Casorati, Giulia. (2021) Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia. Nature Communications, 12. p. 4844.

Yang, C. and Krishnamurthy, S. and Liu, J. and Liu, S. and Lu, X. and Coady, D. J. and Cheng, W. and De Libero, G. and Singhal, A. and Hedrick, J. L. and Yang, Y. Y.. (2016) Broad-Spectrum Antimicrobial Star Polycarbonates Functionalized with Mannose for Targeting Bacteria Residing inside Immune Cells. Advanced Healthcare Materials, 5 (11). pp. 1272-1281.

Shinya, E. and Shimizu, M. and Owaki, A. and Paoletti, S. and Mori, L. and De Libero, G. and Takahashi, H.. (2016) Hemopoietic cell kinase (Hck) and p21-activated kinase 2 (PAK2) are involved in the down-regulation of CD1a lipid antigen presentation by HIV-1 Nef in dendritic cells. Virology, 487. pp. 285-295.

Pereira, C. S. and Sa-Miranda, C. and De Libero, G. and Mori, L. and Macedo, M. F.. (2016) Globotriaosylceramide inhibits iNKT-cell activation in a CD1d-dependent manner. European Journal of Immunology, 46 (1). pp. 147-153.

Mori, L. and Lepore, M. and De Libero, G.. (2016) The Immunology of CD1- and MR1-Restricted T Cells. Annual Review of Immunology, 34. pp. 479-510.

Mani, V. and Paleja, B. and Larbi, K. and Kumar, P. and Tay, J. A. and Siew, J. Y. and Inci, F. and Wang, S. and Chee, C. and Wang, Y. T. and Demirci, U. and De Libero, G. and Singhal, A.. (2016) Microchip-based ultrafast serodiagnostic assay for tuberculosis. Scientific Reports, 6. p. 35845.

Gilleron, M. and Lepore, M. and Layre, E. and Cala-De Paepe, D. and Mebarek, N. and Shayman, J. A. and Canaan, S. and Mori, L. and Carriere, F. and Puzo, G. and De Libero, G.. (2016) Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens. Cell Chemical Biology, 23 (9). pp. 1147-1156.

Camacho, F. and Sarmiento, M. E. and Reyes, F. and Kim, L. and Huggett, J. and Lepore, M. and Otero, O. and Gilleron, M. and Puzo, G. and Norazmi, M. N. and Rook, G. and Mori, L. and De Libero, G. and Acosta, A.. (2016) Selection of phage-displayed human antibody fragments specific for CD1b presenting the Mycobacterium tuberculosis glycolipid Ac2SGL. International Journal of Mycobacteriology, 5 (2). pp. 120-127.

Narang, Vipin and Ramli, Muhamad Azfar and Singhal, Amit and Kumar, Pavanish and de Libero, Gennaro and Poidinger, Michael and Monterola, Christopher. (2015) Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks. PLoS Computational Biology, 11 (9). e1004504.

Lepore, Marco and de Lalla, Claudia and Mori, Lucia and Dellabona, Paolo and De Libero, Gennaro and Casorati, Giulia. (2015) Targeting leukemia by CD1c-restricted T cells specific for a novel lipid antigen. Oncoimmunology, 4 (3). e970463.

De Libero, Gennaro and Lau, Sze-Yi and Mori, Lucia. (2015) Phosphoantigen Presentation to TCR gammadelta Cells, a Conundrum Getting Less Gray Zones. Frontiers in Immunology, 5. p. 679.

Lepore, Marco and de Lalla, Claudia and Gundimeda, S. Ramanjaneyulu and Gsellinger, Heiko and Consonni, Michela and Garavaglia, Claudio and Sansano, Sebastiano and Piccolo, Francesco and Scelfo, Andrea and Häussinger, Daniel and Montagna, Daniela and Locatelli, Franco and Bonini, Chiara and Bondanza, Attilio and Forcina, Alessandra and Li, Zhiyuan and Ni, Guanghui and Ciceri, Fabio and Jenö, Paul and Xia, Chengfeng and Mori, Lucia and Dellabona, Paolo and Casorati, Giulia and De Libero, Gennaro. (2014) A novel self-lipid antigen targets human T cells against CD1c(+) leukemias. Journal of Experimental Medicine, 211 (7). pp. 1363-1377.

Singhal, Amit and Jie, Liu and Kumar, Pavanish and Hong, Gan suay and Leow, Melvin Khee and Paleja, Bhairav and Tsenova, Liana and Kurepina, Natalia and Chen, Jinmiao and Zolezzi, Francesca and Kreiswirth, Barry N. and Poidinger, Michael and Chee, Cynthia and Kaplan, Gilla and Wang, Yee Tang and De Libero, Gennaro. (2014) Metformin as adjunct antituberculosis therapy. Science Translational Medicine, 6 (263). 263ra159.

Ni, Guanghui and Li, Zhiyuan and Liang, Kangjian and Wu, Ting and De Libero, Gennaro and Xia, Chengfeng. (2014) Synthesis and evaluation of immunostimulant plasmalogen lysophosphatidylethanolamine and analogues for natural killer T cells. Bioorganic & medicinal chemistry, 22 (11). pp. 2966-2973.

Mani, Vigneshwaran and Wang, Shuqi and Inci, Fatih and De Libero, Gennaro and Singhal, Amit and Demirci, Utkan. (2014) Emerging technologies for monitoring drug-resistant tuberculosis at the point-of-care. Advanced Drug Delivery Reviews, 78. pp. 105-117.

Lepore, Marco and Kalinichenko, Artem and Colone, Alessia and Paleja, Bhairav and Singhal, Amit and Tschumi, Andreas and Lee, Bernett and Poidinger, Michael and Zolezzi, Francesca and Quagliata, Luca and Sander, Peter and Newell, Evan William and Bertoletti, Antonio and Terracciano, Luigi and De Libero, Gennaro and Mori, Lucia. (2014) Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRbeta repertoire. Nature Communications, 5. p. 3866.

Jo, Juandy and Tandrapah, Anthony T. and Ussher, James E. and Sandalova, Elena and Tang, Xin-Zi and Tan-Garcia, Alfonso and Touchet, Natalie and Hong, Michelle and Chia, Adeline and Gill, Upkar S. and Kennedy, Patrick T. and Tan, Kai Chah and Lee, Kang Hoe and De Libero, Gennaro and Gehring, Adam J. and Willberg, Christian B. and Klenerman, Paul and Bertoletti, Antonio. (2014) Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver. PLoS Pathogens, 10 (6). e1004210.

De Libero, Gennaro and Singhal, Amit and Lepore, Marco and Mori, Lucia. (2014) Nonclassical T cells and their antigens in tuberculosis. Cold Spring Harbor Perspectives in Medicine, 4 (9). a018473.

De Libero, Gennaro and Mori, Lucia. (2014) Professional differences in antigen presentation to iNKT cells. Immunity, 40 (1). pp. 5-7.

De Libero, Gennaro and Mori, Lucia. (2014) The T-Cell Response to Lipid Antigens of; Mycobacterium tuberculosis. Frontiers in immunology, 5. p. 219.

Cavallari, Marco and Stallforth, Pierre and Kalinichenko, Artem and Rathwell, Dominea C. K. and Gronewold, Thomas M. A. and Adibekian, Alexander and Mori, Lucia and Landmann, Regine and Seeberger, Peter H. and De Libero, Gennaro. (2014) A semisynthetic carbohydrate-lipid vaccine that protects against S. pneumoniae in mice. Nature Chemical Biology, 10 (11). pp. 950-956.

Wang, S. and Inci, F. and De Libero, G. and Singhal, A. and Demirci, U.. (2013) Point-of-care assays for tuberculosis: role of nanotechnology/microfluidics. Biotechnology advances, Vol. 31, H. 4. pp. 438-449.

Gau, B. and Lemetais, A. and Lepore, M. and Garcia-Alles, L. F. and Bourdreux, Y. and Mori, L. and Gilleron, M. and De Libero, G. and Puzo, G. and Beau, J. M. and Prandi, J.. (2013) Simplified deoxypropionate acyl chains for Mycobacterium tuberculosis sulfoglycolipid analogues : chain length is essential for high antigenicity. ChemBioChem, Vol. 14, H. 18. pp. 2413-2417.

Tang, X. Z. and Jo, J. and Tan, A. T. and Sandalova, E. and Chia, A. and Tan, K. C. and Lee, K. H. and Gehring, A. J. and De Libero, G. and Bertoletti, A.. (2013) IL-7 licenses activation of human liver intrasinusoidal mucosal-associated invariant T cells. Journal of immunology, Vol. 190, H. 7. pp. 3142-3152.

Vavassori, S. and Kumar, A. and Wan, G. S. and Ramanjaneyulu, G. S. and Cavallari, M. and El Daker, S. and Beddoe, T. and Theodossis, A. and Williams, N. K. and Gostick, E. and Price, D. A. and Soudamini, D. U. and Voon, K. K. and Olivo, M. and Rossjohn, J. and Mori, L. and De Libero, G.. (2013) Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gammadelta T cells. Nature immunology, Vol. 14, H. 9. pp. 908-916.

De Libero, G. and Mori, L.. (2012) Novel insights into lipid antigen presentation. Trends in immunology, Vol. 33, H. 3. pp. 103-111.

Facciotti, F. and Ramanjaneyulu, G. S. and Lepore, M. and Sansano, S. and Cavallari, M. and Kistowska, M. and Forss-Petter, S. and Ni, G. and Colone, A. and Singhal, A. and Berger, J. and Xia, C. and Mori, L. and De Libero, G.. (2012) Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus. Nature immunology, Vol. 13, H. 5. pp. 474-480.

Mori, L. and De Libero, G.. (2012) T cells specific for lipid antigens. Immunologic Research, 53 (1-3). pp. 191-199.

Cala-De Paepe, D. and Layre, E. and Giacometti, G. and Garcia-Alles, L. F. and Mori, L. and Hanau, D. and de Libero, G. and de la Salle, H. and Puzo, G. and Gilleron, M.. (2012) Deciphering the role of CD1e protein in mycobacterial phosphatidyl-myo-inositol mannosides (PIM) processing for presentation by CD1b to T lymphocytes. Journal of biological chemistry, Vol. 287, H. 37. pp. 31494-31502.

Kyriakakis, E. and Cavallari, M. and Pfaff, D. and Fabbro, D. and Mestan, J. and Philippova, M. and De Libero, G. and Erne, P. and Resink, T. J.. (2011) IL-8-mediated angiogenic responses of endothelial cells to lipid antigen activation of iNKT cells depend on EGFR transactivation. Journal of leukocyte biology, Vol. 90, no. 5. pp. 929-939.

Cillo, C. and Schiavo, G. and Cantile, M. and Bihl, M. P. and Sorrentino, P. and Carafa, V. and D' Armiento M., and Roncalli, M. and Sansano, S. and Vecchione, R. and Tornillo, L. and Mori, L. and De Libero, G. and Zucman-Rossi, J. and Terracciano, L.. (2011) The HOX gene network in hepatocellular carcinoma. International journal of cancer, Vol. 129, H. 11. pp. 2577-2587.

Garcia-Alles, L. F. and Collmann, A. and Versluis, C. and Lindner, B. and Guiard, J. and Maveyraud, L. and Huc, E. and Im, J. S. and Sansano, S. and Brando, T. and Julien, S. and Prandi, J. and Gilleron, M. and Porcelli, S. A. and de la Salle, H. and Heck, A. J. and Mori, L. and Puzo, G. and Mourey, L. and De Libero, G.. (2011) Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 43. pp. 17755-17760.

Garcia-Alles, L. F. and Giacometti, G. and Versluis, C. and Maveyraud, L. and de Paepe, D. and Guiard, J. and Tranier, S. and Gilleron, M. and Prandi, J. and Hanau, D. and Heck, A. J. and Mori, L. and De Libero, G. and Puzo, G. and Mourey, L. and de la Salle, H.. (2011) Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 32. pp. 13230-13235.

de Lalla, C. and Lepore, M. and Piccolo, F. M. and Rinaldi, A. and Scelfo, A. and Garavaglia, C. and Mori, L. and De Libero, G. and Dellabona, P. and Casorati, G.. (2011) High-frequency and adaptive-like dynamics of human CD1 self-reactive T cells. European journal of immunology, Vol. 41, H. 3. pp. 602-610.

Facciotti, F. and Cavallari, M. and Angenieux, C. and Garcia-Alles, L. F. and Signorino-Gelo, F. and Angman, L. and Gilleron, M. and Prandi, J. and Puzo, G. and Panza, L. and Xia, C. and Wang, P. G. and Dellabona, P. and Casorati, G. and Porcelli, S. A. and de la Salle, H. and Mori, L. and De Libero, G.. (2011) Fine tuning by human CD1e of lipid-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 34. pp. 14228-14233.

Kyriakakis, Emmanouil and Cavallari, Marco and Andert, Jan and Philippova, Maria and Koella, Christoph and Bochkov, Valery and Erne, Paul and Wilson, S. Brian and Mori, Lucia and Biedermann, Barbara C. and Resink, Therese J. and De Libero, Gennaro. (2010) Invariant natural killer T cells : linking inflammation and neovascularization in human atherosclerosis. European Journal of Immunology, Vol. 40, H. 11. pp. 3268-3279.

Cernadas, Manuela and Cavallari, Marco and Watts, Gerald and Mori, Lucia and De Libero, Gennaro and Brenner, Michael B.. (2010) Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. Journal of immunology, Vol. 184, H. 3. pp. 1235-1241.

De Libero, Gennaro and Mori, Lucia. (2010) The easy virtue of CD1c. Immunity, Vol. 33, H. 6. pp. 831-833.

De Libero, Gennaro and Mori, Lucia. (2010) How the immune system detects lipid antigens. Progress in lipid research, Vol. 49, H. 2. pp. 120-127.

Guiard, Julie and Collmann, Anthony and Garcia-Alles, Luis Fernando and Mourey, Lionel and Brando, Thérèse and Mori, Lucia and Gilleron, Martine and Prandi, Jacques and De Libero, Gennaro and Puzo, Germain. (2009) Fatty acyl structures of mycobacterium tuberculosis sulfoglycolipid govern T cell response. Journal of immunology : official journal of the American Association of Immunologists, Vol. 182. pp. 7030-7037.

Mathew, Thresen and Billaud, Célia and Billich, Andreas and Cavallari, Marco and Nussbaumer, Peter and De Libero, Gennaro and Vasella, Andrea. (2009) Synthesis of 7-aza- and 7-thiasphingosines, and evaluation of their interaction with sphingosine kinases and with T-cells. Chemistry & biodiversity, Vol. 6. pp. 725-738.

Layre, E. and Collmann, A. and Bastian, M. and Mariotti, S. and Czaplicki, J. and Prandi, J. and Mori, L. and Stenger, S. and De Libero, G. and Puzo, G. and Gilleron, M.. (2009) Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells. Chemistry & biology, Vol. 16. pp. 82-92.

Mathew, Thresen and Billich, Andreas and Cavallari, Marco and Bornancin, Frederic and Nussbaumer, Peter and De Libero, Gennaro and Vasella, Andrea. (2009) Synthesis and evaluation of sphingolipid analogues: modification of the hydroxy group at C(1) of 7-oxasphingosine, and of the hydroxy group at C(1) and the amide group of 7-oxaceramides. Chemistry & biodiversity, Vol. 6. pp. 705-724.

Gagliardi, Maria Cristina and Teloni, Raffaela and Giannoni, Federico and Mariotti, Sabrina and Remoli, Maria Elena and Sargentini, Valeria and Videtta, Melissa and Pardini, Manuela and De Libero, Gennaro and Coccia, Eliana Marina and Nisini, Roberto. (2009) Mycobacteria exploit p38 signaling to affect CD1 expression and lipid antigen presentation by human dendritic cells. Infection and immunity, Vol. 77. pp. 4947-4952.

Mathew, Thresen and Cavallari, Marco and Billich, Andreas and Bornancin, Frederic and Nussbaumer, Peter and De Libero, Gennaro and Vasella, Andrea. (2009) 4,5,6-Trisubstituted piperidinones as conformationally restricted ceramide analogues: synthesis and evaluation as inhibitors of sphingosine and ceramide kinases and as NKT cell-stimulatory antigens. Chemistry & biodiversity, Vol. 6. pp. 1688-1715.

Maître, Blandine and Angénieux, Catherine and Wurtz, Virginie and Layre, Emilie and Gilleron, Martine and Collmann, Anthony and Mariotti, Sabrina and Mori, Lucia and Fricker, Dominique and Cazenave, Jean-Pierre and van Dorsselaer, Alain and Gachet, Christian and de Libero, Gennaro and Puzo, Germain and Hanau, Daniel and de la Salle, Henri. (2009) The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments. Biochemical journal : BJ, Vol. 419. pp. 661-668.

De Libero, Gennaro and Collmann, Anthony and Mori, Lucia. (2009) The cellular and biochemical rules of lipid antigen presentation. European journal of immunology, Vol. 39, H. 10. pp. 2648-2656.

Barral, D. C. and Cavallari, M. and McCormick, P. J. and Garg, S. and Magee, A. I. and Bonifacino, J. S. and De Libero, G. and Brenner, M. B.. (2008) CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic, Vol. 9. pp. 1446-1457.

Michieletti, M. and Bracci, A. and Compostella, F. and De Libero, G. and Mori, L. and Fallarini, S. and Lombardi, G. and Panza, L.. (2008) Synthesis of alpha-galactosyl ceramide (KRN7000) and analogues there of via a common precursor and their preliminary biological assessment. The journal of organic chemistry, Vol. 73, H. 22. pp. 9192-9195.

Kistowska, M. and Rossy, E. and Sansano, S. and Gober, H. J. and Landmann, R. and Mori, L. and De Libero, G.. (2008) Dysregulation of the host mevalonate pathway during early bacterial infection activates human TCR gamma delta cells. European Journal of Immunology, Vol. 38. pp. 2200-2209.

Tourne, S. and Maitre, B. and Collmann, A. and Layre, E. and Mariotti, S. and Signorino-Gelo, F. and Loch, C. and Salamero, J. and Gilleron, M. and Angénieux, C. and Cazenave, J. P. and Mori, L. and Hanau, D. and Puzo, G. and De Libero, G. and de la Salle, H.. (2008) Cutting edge : a naturally occurring mutation in CD1e impairs lipid antigen presentation. Journal of immunology, Vol. 180, H. 6. pp. 3642-3646.

Sloma, I. and Zilber, M. T. and Vasselon, T. and Setterblad, N. and Cavallari, M. and Mori, L. and De Libero, G. and Charron, D. and Mooney, N. and Gelin, C.. (2008) Regulation of CD1a Surface Expression and Antigen Presentation by Invariant Chain and Lipid Rafts. Journal of immunology, Vol. 180, H. 2. pp. 980-987.

Guiard, J. and Collmann, A. and Gilleron, M. and Mori, L. and De Libero, G. and Prandi, J. and Puzo, G.. (2008) Synthesis of diacylated trehalose sulfates : candidates for a tuberculosis vaccine. Angewandte Chemie. International edition in English, Vol. 47, H. 50. pp. 9734-9738.

De Libero, G. and Mori, L.. (2008) How T cells get grip on lipid antigens. Current opinion in immunology, Vol. 20, H. 1. pp. 96-104.

Mori, L. and De Libero, G.. (2008) Presentation of lipid antigens to T cells. Immunology letters, Vol. 117. pp. 1-8.

Li, Sai and Kralovics, Robert and De Libero, Gennaro and Theocharides, Alexandre and Gisslinger, Heinz and Skoda, Radek C.. (2008) Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2-V617F mutations. Blood, 111 (7). pp. 3863-3866.