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Items where contributor is "Bettler, Bernhard"

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2018

Porcu, Alessandra and Melis, Miriam and Turecek, Rostislav and Ullrich, Celine and Mocci, Ignazia and Bettler, Bernhard and Gessa, Gian Luigi and Castelli, M. Paola. (2018) Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a Gα; i/o; protein inhibitor. Neuropharmacology, 133. pp. 107-120.

2017

Booker, Sam A. and Althof, Daniel and Gross, Anna and Loreth, Desiree and Muller, Johanna and Unger, Andreas and Fakler, Bernd and Varro, Andrea and Watanabe, Masahiko and Gassmann, Martin and Bettler, Bernhard and Shigemoto, Ryuichi and Vida, Imre and Kulik, Akos. (2017) KCTD12 Auxiliary Proteins Modulate Kinetics of GABAB Receptor-Mediated Inhibition in Cholecystokinin-Containing Interneurons. Cereb Cortex, 27 (3). pp. 2318-2334.

2016

Doly, S. and Shirvani, H. and Gata, G. and Meye, F. J. and Emerit, M. B. and Enslen, H. and Achour, L. and Pardo-Lopez, L. and Yang, S. K. and Armand, V. and Gardette, R. and Giros, B. and Gassmann, M. and Bettler, B. and Mameli, M. and Darmon, M. and Marullo, S.. (2016) GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper. Molecular Psychiatry, 21 (4). pp. 480-490.

Jacobson, Laura H. and Sweeney, Fabian F. and Kaupmann, Klemens and O'Leary, Olivia F. and Gassmann, Martin and Bettler, Bernhard and Cryan, John F.. (2016) Differential roles of GABAB1 subunit isoforms on locomotor responses to acute and repeated administration of cocaine. Behavioral Brain Research, 298 (Pt B). pp. 12-16.

Jurado-Parras, Maria Teresa and Delgado-Garcia, José M. and Sanchez-Campusano, Raudel and Gassmann, Martin and Bettler, Bernhard and Gruart, Agnès. (2016) Presynaptic GABAB Receptors Regulate Hippocampal Synapses during Associative Learning in Behaving Mice. PLoS One, 11 (2). e0148800.

Pin, Jean-Philippe and Bettler, Bernhard. (2016) Organization and functions of mGlu and GABAB receptor complexes. Nature, 540 (7631). pp. 60-68.

Sailer, Martin H. and Sarvepalli, Durga and Bregere, Catherine and Fisch, Urs and Guentchev, Marin and Weller, Michael and Guzman, Raphael and Bettler, Bernhard and Ghosh, Arkasubhra and Hutter, Gregor. (2016) An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (114). p. 54018.

Schwenk, Jochen and Perez-Garci, Enrique and Schneider, Andy and Kollewe, Astrid and Gauthier-Kemper, Anne and Fritzius, Thorsten and Raveh, Adi and Dinamarca, Margarita C. and Hanuschkin, Alexander and Bildl, Wolfgang and Klingauf, Jürgen and Gassmann, Martin and Schulte, Uwe and Bettler, Bernhard and Fakler, Bernd. (2016) Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics. Natural Neuroscience, 19 (2). pp. 233-242.

Zhang, Juen and Tan, Lubin and Ren, Yuqi and Liang, Jingwen and Lin, Rui and Feng, Qiru and Zhou, Jingfeng and Hu, Fei and Ren, Jing and Wei, Chao and Yu, Tao and Zhuang, Yinghua and Bettler, Bernhard and Wang, Fengchao and Luo, Minmin. (2016) Presynaptic Excitation via GABAB Receptors in Habenula Cholinergic Neurons Regulates Fear Memory Expression. Cell, 166 (3). pp. 716-728.

2015

Giachino, C. and Boulay, J. L. and Ivanek, R. and Alvarado, A. and Tostado, C. and Lugert, S. and Tchorz, J. and Coban, M. and Mariani, L. and Bettler, B. and Lathia, J. and Frank, S. and Pfister, S. and Kool, M. and Taylor, V.. (2015) A tumor suppressor function for Notch signaling in forebrain tumor subtypes. Cancer Cell, 28 (6). pp. 730-742.

Cathomas, F. and Stegen, M. and Sigrist, H. and Schmid, L. and Seifritz, E. and Gassmann, M. and Bettler, B. and Pryce, C. R.. (2015) Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders. Translational Psychiatry, 5. e510.

Hanack, C. and Moroni, M. and Lima, W. C. and Wende, H. and Kirchner, M. and Adelfinger, L. and Schrenk-Siemens, K. and Tappe-Theodor, A. and Wetzel, C. and Kuich, P. H. and Gassmann, M. and Roggenkamp, D. and Bettler, B. and Lewin, G. R. and Selbach, M. and Siemens, J.. (2015) GABA Blocks Pathological but Not Acute TRPV1 Pain Signals. Cell, 160 (4). pp. 759-770.

Harmeier, A. and Obermueller, S. and Meyer, C. A. and Revel, F. G. and Buchy, D. and Chaboz, S. and Dernick, G. and Wettstein, J. G. and Iglesias, A. and Rolink, A. and Bettler, B. and Hoener, M. C.. (2015) Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers. European Neuropsychopharmacology, 25 (11). pp. 2049-2061.

Rajalu, M. and Fritzius, T. and Adelfinger, L. and Jacquier, V. and Besseyrias, V. and Gassmann, M. and Bettler, B.. (2015) Pharmacological characterization of GABAB receptor subtypes assembled with auxiliary KCTD subunits. Neuropharmacology, 88. pp. 145-154.

Takahashi, A. and Lee, R. X. and Iwasato, T. and Itohara, S. and Arima, H. and Bettler, B. and Miczek, K. A. and Koide, T.. (2015) Glutamate Input in the Dorsal Raphe Nucleus As a Determinant of Escalated Aggression in Male Mice. Journal of Neuroscience, 35 (16). pp. 6452-6463.

Varani, A. P. and Pedron, V. T. and Machado, L. M. and Antonelli, M. C. and Bettler, B. and Balerio, G. N.. (2015) Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal. Neuropharmacology, 90. pp. 90-101.

Vertkin, I. and Styr, B. and Slomowitz, E. and Ofir, N. and Shapira, I. and Berner, D. and Fedorova, T. and Laviv, T. and Barak-Broner, N. and Greitzer-Antes, D. and Gassmann, M. and Bettler, B. and Lotan, I. and Slutsky, I.. (2015) GABAB receptor deficiency causes failure of neuronal homeostasis in hippocampal networks. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 112 (25). E3291-9.

2014

Giachino, C. and Barz, M. and Tchorz, J. S. and Tome, M. and Gassmann, M. and Bischofberger, J. and Bettler, B. and Taylor, V.. (2014) GABA suppresses neurogenesis in the adult hippocampus through GABAB receptors. Development, Vol. 141, H. 1. pp. 83-90.

Adelfinger, Lisa and Turecek, Rostislav and Ivankova, Klara and Jensen, Anders A. and Moss, Stephen J. and Gassmann, Martin and Bettler, Bernhard. (2014) GABAB receptor phosphorylation regulates KCTD12-induced K(+) current desensitization. Biochemical Pharmacology, 91 (3). pp. 369-379.

Di Giorgio, Noelia P. and Semaan, Sheila J. and Kim, Joshua and Lopez, Paula V. and Bettler, Bernhard and Libertun, Carlos and Lux-Lantos, Victoria A. and Kauffman, Alexander S.. (2014) Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice. Endocrinology, 155 (3). pp. 1033-1044.

Faroni, Alessandro and Castelnovo, Luca Franco and Procacci, Patrizia and Caffino, Lucia and Fumagalli, Fabio and Melfi, Simona and Gambarotta, Giovanna and Bettler, Bernhard and Wrabetz, Lawrence and Magnaghi, Valerio. (2014) Deletion of GABA-B receptor in Schwann cells regulates remak bundles and small nociceptive C-fibers. Glia, 62 (4). pp. 548-565.

Martin, Cédric B. P. and Gassmann, Martin and Chevarin, Caroline and Hamon, Michel and Rudolph, Uwe and Bettler, Bernhard and Lanfumey, Laurence and Mongeau, Raymond. (2014) Effect of genetic and pharmacological blockade of GABA receptors on the 5-HT2C receptor function during stress. Journal of Neurochemistry, 131 (5). pp. 566-572.

O'Leary, Olivia F. and Felice, Daniela and Galimberti, Stefano and Savignac, Hélène M. and Bravo, Javier A. and Crowley, Tadgh and El Yacoubi, Malika and Vaugeois, Jean Marie and Gassmann, Martin and Bettler, Bernhard and Dinan, Timothy G. and Cryan, John F.. (2014) GABAB(1) receptor subunit isoforms differentially regulate stress resilience. Proceedings of the National Academy of Sciences of the United States of America, 111 (42). pp. 15232-15237.

Turecek, Rostislav and Schwenk, Jochen and Fritzius, Thorsten and Ivankova, Klara and Zolles, Gerd and Adelfinger, Lisa and Jacquier, Valérie and Besseyrias, Valérie and Gassmann, Martin and Schulte, Uwe and Fakler, Bernd and Bettler, Bernhard. (2014) Auxiliary GABAB receptor subunits uncouple G protein betagamma subunits from effector channels to induce desensitization. Neuron, 82 (5). pp. 1032-1044.

Varani, Andrés P. and Pedron, Valeria T. and Bettler, Bernhard and Balerio, Graciela N.. (2014) Involvement of GABAB receptors in biochemical alterations induced by anxiety-related responses to nicotine in mice: genetic and pharmacological approaches. Neuropharmacology, 81. pp. 31-41.

2013

Bonaventura, M. M. and Rodriguez, D. and Ferreira, M. L. and Crivello, M. and Repetto, E. M. and Bettler, B. and Libertun, C. and Lux-Lantos, V. A.. (2013) Sex differences in insulin resistance in GABAB1 knockout mice. Life sciences, Vol. 92, H. 3. pp. 175-182.

Dill, M. T. and Tornillo, L. and Fritzius, T. and Terracciano, L. and Semela, D. and Bettler, B. and Heim, M. H. and Tchorz, J. S.. (2013) Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology, Vol. 57, No. 4. pp. 1607-1619.

Craig, Michael T. and Mayne, Elizabeth W. and Bettler, Bernhard and Paulsen, Ole and McBain, Chris J.. (2013) Distinct roles of GABAB1a- and GABAB1b-containing GABAB receptors in spontaneous and evoked termination of persistent cortical activity. The Journal of physiology, Vol. 591, Nr. 4. pp. 835-843.

Foster, Joshua D. and Kitchen, Ian and Bettler, Bernhard and Chen, Ying. (2013) GABAB receptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output. British journal of pharmacology, Vol. 168, no. 8. pp. 1808-1819.

Di Giorgio, N. P. and Catalano, P. N. and Lopez, P. V. and Gonzalez, B. and Semaan, S. J. and Lopez, G. C. and Kauffman, A. S. and Rulli, S. B. and Somoza, G. M. and Bettler, B. and Libertun, C. and Lux-Lantos, V. A.. (2013) Lack of functional GABA receptors alters Kiss1 , Gnrh1 and Gad1 mRNA expression in the medial basal hypothalamus at postnatal day 4. Neuroendocrinology, 98 (3). pp. 212-223.

Crivello, M. and Bonaventura, M. M. and Chamson-Reig, A. and Arany, E. and Bettler, B. and Libertun, C. and Lux-Lantos, V.. (2013) Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors. American journal of physiology. Endocrinology and Metabolism, Vol. 304, H. 10 , E1064-E1076.

Booker, S. A. and Gross, A. and Althof, D. and Shigemoto, R. and Bettler, B. and Frotscher, M. and Hearing, M. and Wickman, K. and Watanabe, M. and Kulik, A. and Vida, I.. (2013) Differential GABAB-receptor-mediated effects in perisomatic- and dendrite-targeting parvalbumin interneurons. Journal of Neuroscience, 33 (18). pp. 7961-7974.

Wedemeyer, C. and Zorrilla de San Martin, J. and Ballestero, J. and Gomez-Casati, M. E. and Torbidoni, A. V. and Fuchs, P. A. and Bettler, B. and Elgoyhen, A. B. and Katz, E.. (2013) Activation of presynaptic GABA(B(1a,2)) receptors inhibits synaptic transmission at mammalian inhibitory cholinergic olivocochlear-hair cell synapses. Journal of Neuroscience, 33 (39). pp. 15477-15487.

Ivankova, K. and Turecek, R. and Fritzius, T. and Seddik, R. and Prezeau, L. and Comps-Agrar, L. and Pin, J. P. and Fakler, B. and Besseyrias, V. and Gassmann, M. and Bettler, B.. (2013) Up-regulation of GABA(B) receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12). Journal of biological chemistry, Vol. 288, H. 34. pp. 24848-24856.

Ito, Y. and Banno, R. and Shibata, M. and Adachi, K. and Hagimoto, S. and Hagiwara, D. and Ozawa, Y. and Goto, M. and Suga, H. and Sugimura, Y. and Bettler, B. and Oiso, Y. and Arima, H.. (2013) GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high-fat diet. Journal of Neuroscience, 33 (43). pp. 17166-17173.

2012

Tchorz, J. S. and Suply, T. and Ksiazek, I. and Giachino, C. and Cloetta, D. and Danzer, C. P. and Doll, T. and Isken, A. and Lemaistre, M. and Taylor, V. and Bettler, B. and Kinzel, B. and Mueller, M.. (2012) A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PLoS ONE, Vol. 7, H. 1 , e30011.

Zecharia, A. Y. and Yu, X. and Gotz, T. and Ye, Z. and Carr, D. R. and Wulff, P. and Bettler, B. and Vyssotski, A. L. and Brickley, S. G. and Franks, N. P. and Wisden, W.. (2012) GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness. Journal of Neuroscience, 32 (38). pp. 13062-13075.

Yang, Jiwen and Bücker, Sandra and Jungblut, Benno and Böttger, Thomas and Cinnamon, Yuval and Tchorz, Jan and Müller, Matthias and Bettler, Bernhard and Harvey, Richard and Sun, Qing-Yuan and Schneider, Andre and Braun, Thomas. (2012) Inhibition of Notch2 by Numb/Numblike controls myocardial compaction in the heart. Cardiovascular research, Vol. 96, H. 2. pp. 276-285.

Gassmann, M. and Bettler, B.. (2012) Regulation of neuronal GABA(B) receptor functions by subunit composition. Nature reviews. Neuroscience, Vol. 13, H. 6. pp. 380-394.

Moloney, Rachel D. and O'Leary, Olivia F. and Felice, Daniela and Bettler, Bernhard and Dinan, Timothy G. and Cryan, John F.. (2012) Early-life stress induces visceral hypersensitivity in mice. Neuroscience letters, Vol. 512, H. 2. pp. 99-102.

Tchorz, J. S. and Tome, M. and Cloetta, D. and Sivasankaran, B. and Grzmil, M. and Huber, R. M. and Rutz-Schatzmann, F. and Kirchhoff, F. and Schaeren-Wiemers, N. and Gassmann, M. and Hemmings, B. A. and Merlo, A. and Bettler, B.. (2012) Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell death & disease, Vol. 3 , e325.

Seddik, Riad and Jungblut, Stefan P. and Silander, Olin K. and Rajalu, Mathieu and Fritzius, Thorsten and Besseyrias, Valérie and Jacquier, Valérie and Fakler, Bernd and Gassmann, Martin and Bettler, Bernhard. (2012) Opposite effects of KCTD subunit domains on GABA(B) receptor-mediated desensitization. The Journal of biological chemistry, Vol. 287, H. 47. pp. 39869-39877.

Varani, Andrés P. and Moutinho, Lirane Machado and Bettler, Bernhard and Balerio, Graciela N.. (2012) Acute behavioural responses to nicotine and nicotine withdrawal syndrome are modified in GABA(B1) knockout mice. Neuropharmacology, Vol. 63, H. 5. pp. 863-872.

2011

Comps-Agrar, Laëtitia and Kniazeff, Julie and Nørskov-Lauritsen, Lenea and Maurel, Damien and Gassmann, Martin and Gregor, Nathalie and Prézeau, Laurent and Bettler, Bernhard and Durroux, Thierry and Trinquet, Eric and Pin, Jean-Philippe. (2011) The oligomeric state sets GABA(B) receptor signalling efficacy. The EMBO journal, Vol. 30, H. 12. pp. 2336-2349.

Revel, F. G. and Moreau, J. L. and Gainetdinov, R. R. and Bradaia, A. and Sotnikova, T. D. and Mory, R. and Durkin, S. and Zbinden, K. G. and Norcross, R. and Meyer, C. A. and Metzler, V. and Chaboz, S. and Ozmen, L. and Trube, G. and Pouzet, B. and Bettler, B. and Caron, M. G. and Wettstein, J. G. and Hoener, M. C.. (2011) TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity. Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, H. 20. pp. 8485-8490.

Metz, M. and Gassmann, M. and Fakler, B. and Schaeren-Wiemers, N. and Bettler, B.. (2011) Distribution of the auxiliary GABA(B) receptor subunits KCTD8, 12, 12b and 16 in the mouse brain. The journal of comparative neurology, Vol. 519, H. 8. pp. 1435-1454.

Laviv, T. and Vertkin, I. and Berdichevsky, Y. and Fogel, H. and Riven, I. and Bettler, B. and Slesinger, P. A. and Slutsky, I.. (2011) Compartmentalization of the GABAB receptor signaling complex is required for presynaptic inhibition at hippocampal synapses. Journal of Neuroscience, 31 (35). pp. 12523-12532.

2010

Biermann, Barbara and Ivankova-Susankova, Klara and Bradaia, Amyaouch and Abdel Aziz, Said and Besseyrias, Valerie and Kapfhammer, Josef P. and Missler, Markus and Gassmann, Martin and Bettler, Bernhard. (2010) The Sushi domains of GABAB receptors function as axonal targeting signals. Journal of Neuroscience, 30 (4). pp. 1385-1394.

Schwenk, Jochen and Metz, Michaela and Zolles, Gerd and Turecek, Rostislav and Fritzius, Thorsten and Bildl, Wolfgang and Tarusawa, Etsuko and Kulik, Akos and Unger, Andreas and Ivankova, Klara and Seddik, Riad and Tiao, Jim Y. and Rajalu, Mathieu and Trojanova, Johana and Rohde, Volker and Gassmann, Martin and Schulte, Uwe and Fakler, Bernd and Bettler, Bernhard. (2010) Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. Nature, Vol. 465, H. 7295. pp. 231-235.

Catalano, Paolo N. and Di Giorgio, Noelia and Bonaventura, María M. and Bettler, Bernhard and Libertun, Carlos and Lux-Lantos, Victoria A.. (2010) Lack of functional GABA(B) receptors alters GnRH physiology and sexual dimorphic expression of GnRH and GAD-67 in the brain. American journal of physiology. Endocrinology and metabolism, Vol. 298, H. 3 , E683-E696.

Vienne, Julie and Bettler, Bernhard and Franken, Paul and Tafti, Mehdi. (2010) Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation. Journal of Neuroscience, 30 (42). pp. 14194-14204.

Maurice, Pascal and Daulat, Avais M. and Turecek, Rostislav and Ivankova-Susankova, Klara and Zamponi, Francesco and Kamal, Maud and Clement, Nathalie and Guillaume, Jean-Luc and Bettler, Bernhard and Galès, Céline and Delagrange, Philippe and Jockers, Ralf. (2010) Molecular organization and dynamics of the melatonin MT ? receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling. The EMBO journal, Vol. 29, H. 21. pp. 3646-3659.

Pinard, Audrée and Seddik, Riad and Bettler, Bernhard. (2010) GABAB receptors : physiological functions and mechanisms of diversity. Advances in pharmacology, Vol. 58. pp. 231-255.

Guetg, Nicole and Aziz, Said Abdel and Holbro, Niklaus and Turecek, Rostislav and Rose, Tobias and Seddik, Riad and Gassmann, Martin and Moes, Suzette and Jenoe, Paul and Oertner, Thomas G. and Casanova, Emilio and Bettler, Bernhard. (2010) NMDA receptor-dependent GABA(B) receptor internalization via CaMKII phosphorylation of serine 867 in GABA(B1). Proceedings of the National Academy of Sciences (PNAS), 107 (31). pp. 13924-13929.

2009

Guetg, Nicole and Seddik, Riad and Vigot, Réjan and Turecek, Rostislav and Gassmann, Martin and Vogt, Kaspar E. and Bräuner-Osborne, Hans and Shigemoto, Ryuichi and Kretz, Oliver and Frotscher, Michael and Kulik, Akos and Bettler, Bernhard. (2009) The GABAB1a isoform mediates heterosynaptic depression at hippocampal mossy fiber synapses. Journal of Neuroscience, 29 (5). pp. 1414-1423.

Matsuki, Taizo and Nomiyama, Mika and Takahira, Hitomi and Hirashima, Noriko and Kunita, Satoshi and Takahashi, Satoru and Yagami, Ken-ichi and Kilduff, Thomas S. and Bettler, Bernhard and Yanagisawa, Masashi and Sakurai, Takeshi. (2009) Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 11. pp. 4459-4464.

Bradaia, Amyaouch and Trube, Gerhard and Stalder, Henri and Norcross, Roger D. and Ozmen, Laurence and Wettstein, Joseph G. and Pinard, Audrée and Buchy, Danièle and Gassmann, Martin and Hoener, Marius C. and Bettler, Bernhard. (2009) The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, No. 47. pp. 20081-20086.

Fernández-Alacid, Laura and Aguado, Carolina and Ciruela, Francisco and Martín, Ricardo and Colón, José and Cabañero, María José and Gassmann, Martin and Watanabe, Masahiko and Shigemoto, Ryuichi and Wickman, Kevin and Bettler, Bernhard and Sánchez-Prieto, José and Luján, Rafael. (2009) Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. Journal of neurochemistry, Vol. 110, H. 4. pp. 1363-1376.

Casanova, Emilio and Guetg, Nicole and Vigot, Réjan and Seddik, Riad and Julio-Pieper, Marcela and Hyland, Niall P. and Cryan, John F. and Gassmann, Martin and Bettler, Bernhard. (2009) A mouse model for visualization of GABA(B) receptors. Genesis, Vol. 47, H. 9. pp. 595-602.

Gangadharan, Vijayan and Agarwal, Nitin and Brugger, Stefan and Tegeder, Imgard and Bettler, Bernhard and Kuner, Rohini and Kurejova, Martina. (2009) Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo. Molecular pain, Vol. 5 , 68.

Tchorz, Jan S. and Kinter, Jochen and Müller, Matthias and Tornillo, Luigi and Heim, Markus H. and Bettler, Bernhard. (2009) Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology : official journal of the American Association for the Study of Liver Diseases, Vol. 50, No. 3. pp. 871-879.

Wellendorph, Petrine and Johansen, Lars Dan and Jensen, Anders A. and Casanova, Emilio and Gassmann, Martin and Deprez, Pierre and Clément-Lacroix, Philippe and Bettler, Bernhard and Bräuner-Osborne, Hans. (2009) No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions. Journal of molecular endocrinology, Vol. 42, no. 3. pp. 215-223.

Maison, Stéphane F. and Casanova, Emilio and Holstein, Gay R. and Bettler, Bernhard and Liberman, M. Charles. (2009) Loss of GABAB receptors in cochlear neurons: threshold elevation suggests modulation of outer hair cell function by type II afferent fibers. Journal of the Association for Research in Otolaryngology, Vol. 10, no. 1. pp. 50-63.

2008

Tiao, Jim Y. and Bradaia, Amyaouch and Biermann, Barbara and Kaupmann, Klemens and Metz, Michaela and Haller, Corinne and Rolink, Antonius G. and Pless, Elin and Barlow, Paul N. and Gassmann, Martin and Bettler, Bernhard. (2008) The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. Journal of biological chemistry, Vol. 283, H. 45. pp. 31005-31011.

Magnaghi, Valerio and Ballabio, Marinella and Camozzi, Francesca and Colleoni, Mariapia and Consoli, Antonio and Gassmann, Martin and Lauria, Giuseppe and Motta, Marcella and Procacci, Patrizia and Trovato, Anna Elisa and Bettler, Bernhard. (2008) Altered peripheral myelination in mice lacking GABAB receptors. Molecular and cellular neuroscience, Vol. 37, H. 3. pp. 599-609.

Lindemann, Lothar and Meyer, Claas Aiko and Jeanneau, Karine and Bradaia, Amyaouch and Ozmen, Laurence and Bluethmann, Horst and Bettler, Bernhard and Wettstein, Joseph G. and Borroni, Edilio and Moreau, Jean-Luc and Hoener, Marius C.. (2008) Trace amine-associated receptor 1 modulates dopaminergic activity. Journal of pharmacology and experimental therapeutics, Vol. 324, H. 3. pp. 948-956.

Bonaventura, M. M. and Catalano, P. N. and Chamson-Reig, A. and Arany, E. and Hill, D. and Bettler, B. and Saravia, F. and Libertun, C. and Lux-Lantos, V. A.. (2008) GABAB receptors and glucose homeostasis : evaluation in GABAB receptor knockout mice. American journal of physiology. Endocrinology and metabolism, Vol. 294, H. 1 , E157-E167.

2007

Ksiazek, Iwona and Burkhardt, Constanze and Lin, Shuo and Seddik, Riad and Maj, Marcin and Bezakova, Gabriela and Jucker, Mathias and Arber, Silvia and Caroni, Pico and Sanes, Joshua R. and Bettler, Bernhard and Ruegg, Markus A.. (2007) Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. Journal of Neuroscience, 27 (27). pp. 7183-7195.

Ulrich, Daniel and Bettler, Bernhard. (2007) GABA(B) receptors: synaptic functions and mechanisms of diversity. Current opinion in neurobiology, Vol. 17, H. 3. pp. 298-303.

Pinheiro, Paulo S. and Perrais, David and Coussen, Françoise and Barhanin, Jacques and Bettler, Bernhard and Mann, Jeffrey R. and Malva, João O. and Heinemann, Stephen F. and Mulle, Christophe. (2007) GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 29. pp. 12181-12186.

Chang, Wenhan and Tu, Chialing and Cheng, Zhiqiang and Rodriguez, Luis and Chen, Tsui-Hua and Gassmann, Martin and Bettler, Bernhard and Margeta, Marta and Jan, Lily Y. and Shoback, Dolores. (2007) Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor : Studies with HEK-293 cells and neurons. Journal of biological chemistry, Vol. 282, H. 34. pp. 25030-25040.

Ulrich, Daniel and Besseyrias, Valérie and Bettler, Bernhard. (2007) Functional mapping of GABA(B)-receptor subtypes in the thalamus. Journal of Neurophysiology, Vol. 98, H. 6. pp. 3791-3795.

Cheng, Zhiqiang and Tu, Chialing and Rodriguez, Luis and Chen, Tsui-Hua and Dvorak, Melita M. and Margeta, Marta and Gassmann, Martin and Bettler, Bernhard and Shoback, Dolores and Chang, Wenhan. (2007) Type B gamma-aminobutyric acid receptors modulate the function of the extracellular Ca2+-sensing receptor and cell differentiation in murine growth plate chondrocytes. Endocrinology, Vol. 148, No. 10. pp. 4984-4992.

Jacobson, Laura H. and Kelly, Peter H. and Bettler, Bernhard and Kaupmann, Klemens and Cryan, John F.. (2007) Specific roles of GABA(B(1)) receptor isoforms in cognition. Behavioural brain research, Vol. 181, no. 1. pp. 158-162.

Jacobson, Laura H. and Bettler, Bernhard and Kaupmann, Klemens and Cryan, John F.. (2007) Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology, Vol. 190, no. 4. pp. 541-553.

Mutel, Vincent and Bettler, Bernhard. (2007) The pros of not being competitive. Current neuropharmacology, Vol. 5, H. 3. p. 148.

2006

Bettler, Bernhard and Tiao, Jim Yu-Hsiang. (2006) Molecular diversity, trafficking and subcellular localization of GABAB receptors. Pharmacology & therapeutics, Vol. 110, no. 3. pp. 533-543.

Rey-Roldán, Estela B. and Bianchi, María S. and Bettler, Bernhard and Becu-Villalobos, Damasia and Lux-Lantos, Victoria A. and Libertun, Carlos. (2006) Adenohypophyseal and hypothalamic GABA B receptor subunits are downregulated by estradiol in adult female rats. Life sciences, Vol. 79, no. 4. pp. 342-350.

Vacher, Claire-Marie and Gassmann, Martin and Desrayaud, Sandrine and Challet, Etienne and Bradaia, Amyaouch and Hoyer, Daniel and Waldmeier, Peter and Kaupmann, Klemens and Pévet, Paul and Bettler, Bernhard. (2006) Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice. Journal of neurochemistry, Vol. 97, H. 4. pp. 979-991.

Engle, M. P. and Gassman, M. and Sykes, K. T. and Bettler, B. and Hammond, D. L.. (2006) Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat. Neuroscience, Vol. 138, H. 4. pp. 1277-1287.

Pérez-Garci, Enrique and Gassmann, Martin and Bettler, Bernhard and Larkum, Matthew E.. (2006) The GABAB1b isoform mediates long-lasting inhibition of dendritic Ca2+ spikes in layer 5 somatosensory pyramidal neurons. Neuron, Vol. 50, H. 4. pp. 603-616.

Vigot, Réjan and Barbieri, Samuel and Bräuner-Osborne, Hans and Turecek, Rostislav and Shigemoto, Ryuichi and Zhang, Yan-Ping and Luján, Rafael and Jacobson, Laura H. and Biermann, Barbara and Fritschy, Jean-Marc and Vacher, Claire-Marie and Müller, Matthias and Sansig, Gilles and Guetg, Nicole and Cryan, John F. and Kaupmann, Klemens and Gassmann, Martin and Oertner, Thomas G. and Bettler, Bernhard. (2006) Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron, Vol. 50, H. 4. pp. 589-601.

Kulik, Akos and Vida, Imre and Fukazawa, Yugo and Guetg, Nicole and Kasugai, Yu and Marker, Cheryl L. and Rigato, Franck and Bettler, Bernhard and Wickman, Kevin and Frotscher, Michael and Shigemoto, Ryuichi. (2006) Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. Journal of neuroscience, Vol. 26, H. 16. pp. 4289-4297.

Jacobson, Laura H. and Kelly, Peter H. and Bettler, Bernhard and Kaupmann, Klemens and Cryan, John F.. (2006) GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. Journal of neuroscience, Vol. 26, H. 34. pp. 8800-8803.

Jacobson, Laura H. and Bettler, Bernhard and Kaupmann, Klemens and Cryan, John F.. (2006) GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. The Journal of Pharmacology and Experimental Therapeutics, Vol. 319, H. 3. pp. 1317-1326.

Shaban, Hamdy and Humeau, Yann and Herry, Cyril and Cassasus, Guillaume and Shigemoto, Ryuichi and Ciocchi, Stephane and Barbieri, Samuel and van der Putten, Herman and Kaupmann, Klemens and Bettler, Bernhard and Lüthi, Andreas. (2006) Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nature neuroscience, Vol. 9, H. 8. pp. 1028-1035.

2005

Sauter, Kathrin and Grampp, Thomas and Fritschy, Jean-Marc and Kaupmann, Klemens and Bettler, Bernhard and Mohler, Hanns and Benke, Dietmar. (2005) Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors. Journal of biological chemistry, Vol. 280, H. 39. pp. 33566-33572.

Mombereau, Cedric and Kaupmann, Klemens and Gassmann, Martin and Bettler, Bernhard and van der Putten, Herman and Cryan, John F.. (2005) Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. NeuroReport, Vol. 16, H. 3. pp. 307-310.

Gassmann, Martin and Haller, Corinne and Stoll, Yanick and Aziz, Said Abdel and Biermann, Barbara and Mosbacher, Johannes and Kaupmann, Klemens and Bettler, Bernhard. (2005) The RXR-type endoplasmic reticulum-retention/retrieval signal of GABAB1 requires distant spacing from the membrane to function. Molecular pharmacology, Vol. 68, H. 1. pp. 137-144.

Bianchi, María S. and Lux-Lantos, Victoria A. and Bettler, Bernhard and Libertun, Carlos. (2005) Expression of gamma-aminobutyric acid B receptor subunits in hypothalamus of male and female developing rats. Developmental brain research, Vol. 160, no. 2. pp. 124-129.

Catalano, Paolo N. and Bonaventura, María Marta and Silveyra, Patricia and Bettler, Bernhard and Libertun, Carlos and Lux-Lantos, Victoria A.. (2005) GABA(B1) knockout mice reveal alterations in prolactin levels, gonadotropic axis, and reproductive function. Neuroendocrinology, 82 (5-6). pp. 294-305.

Deriu, Daniela and Gassmann, Martin and Firbank, Susan and Ristig, Dorothee and Lampert, Christina and Mosbacher, Johannes and Froestl, Wolfgang and Kaupmann, Klemens and Bettler, Bernhard and Grütter, Markus G.. (2005) Determination of the minimal functional ligand-binding domain of the GABAB1b receptor. The biochemical journal, Vol. 386, H. Pt. 3. pp. 423-431.

2004

Merlo, Adrian and Bettler, Bernhard. (2004) Glioblastomas on the move. Science's STKE, Vol. 2004, no. 229 , pe18.

Tabata, Toshihide and Araishi, Kenji and Hashimoto, Kouichi and Hashimotodani, Yuki and van der Putten, Herman and Bettler, Bernhard and Kano, Masanobu. (2004) Ca2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA. Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 48. pp. 16952-16957.

Rüttimann, Elisabeth and Vacher, Claire-Marie and Gassmann, Martin and Kaupmann, Klemens and Van der Putten, Herman and Bettler, Bernhard. (2004) Altered hippocampal expression of calbindin-D-28k and calretinin in GABA(B(1))-deficient mice. Biochemical Pharmacology, Volume 68, Issue 8. pp. 1613-1620.

Fritschy, Jean-Marc and Sidler, Corinne and Parpan, Franziska and Gassmann, Martin and Kaupmann, Klemens and Bettler, Bernhard and Benke, Dietmar. (2004) Independent maturation of the GABA(B) receptor subunits GABA(B1) and GABA(B2) during postnatal development in rodent brain. The Journal of comparative neurology, Vol. 477, H. 3. pp. 235-252.

Gassmann, Martin and Shaban, Hamdy and Vigot, Réjan and Sansig, Gilles and Haller, Corinne and Barbieri, Samuel and Humeau, Yann and Schuler, Valérie and Müller, Matthias and Kinzel, Bernd and Klebs, Klaus and Schmutz, Markus and Froestl, Wolfgang and Heid, Jakob and Kelly, Peter H. and Gentry, Clive and Jaton, Anne-Lise and Van der Putten, Herman and Mombereau, Cédric and Lecourtier, Lucas and Mosbacher, Johannes and Cryan, John F. and Fritschy, Jean-Marc and Lüthi, Andreas and Kaupmann, Klemens and Bettler, Bernhard. (2004) Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. Journal of neuroscience, Vol. 24, H. 27. pp. 6086-6097.

Bettler, Bernhard and Kaupmann, Klemens and Mosbacher, Johannes and Gassmann, Martin. (2004) Molecular structure and physiological functions of GABA(B) receptors. Physiological reviews, Vol. 84, no. 3. pp. 835-867.

Haller, Corinne and Casanova, Emilio and Müller, Matthias and Vacher, Claire-Marie and Vigot, Rejan and Doll, Thierry and Barbieri, Samuel and Gassmann, Martin and Bettler, Bernhard. (2004) Floxed allele for conditional inactivation of the GABAB(1) gene. Genesis, Vol. 40, H. 3. pp. 125-130.

Cryan, John F. and Kelly, Peter H. and Chaperon, Frederique and Gentsch, Conrad and Mombereau, Cedric and Lingenhoehl, Kurt and Froestl, Wolfgang and Bettler, Bernhard and Kaupmann, Klemens and Spooren, Will P. J. M.. (2004) Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine) : anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. The Journal of Pharmacology and Experimental Therapeutics, Vol. 310, H. 3. pp. 952-963.

Bianchi, María S. and Catalano, Paolo N. and Bonaventura, María M. and Silveyra, Patricia and Bettler, Bernhard and Libertun, Carlos and Lux-Lantos, Victoria A. R.. (2004) Effect of androgens on sexual differentiation of pituitary gamma-aminobutyric acid receptor subunit GABA(B) expression. Neuroendocrinology, 80 (3). pp. 129-142.

2003

Saghatelyan, Armen K. and Snapyan, Marina and Gorissen, Silke and Meigel, Inge and Mosbacher, Johannes and Kaupmann, Klemens and Bettler, Bernhard and Kornilov, Andrei V. and Nifantiev, Nikolay E. and Sakanyan, Vehary and Schachner, Melitta and Dityatev, Alexander. (2003) Recognition molecule associated carbohydrate inhibits postsynaptic GABA(B) receptors : a mechanism for homeostatic regulation of GABA release in perisomatic synapses. Molecular and cellular neuroscience, Vol. 24, H. 2. pp. 271-282.

Kaupmann, Klemens and Cryan, John F. and Wellendorph, Petrine and Mombereau, Cedric and Sansig, Gilles and Klebs, Klaus and Schmutz, Markus and Froestl, Wolfgang and van der Putten, Herman and Mosbacher, Johannes and Bräuner-Osborne, Hans and Waldmeier, Peter and Bettler, Bernhard. (2003) Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. The European journal of neuroscience, Vol. 18, H. 10. pp. 2722-2730.

Furtinger, Sabine and Bettler, Bernhard and Sperk, Günther. (2003) Altered expression of GABAB receptors in the hippocampus after kainic-acid-induced seizures in rats. Molecular brain research, Vol. 113, no. 1-2. pp. 107-115.

Froestl, Wolfgang and Bettler, Bernhard and Bittiger, Helmut and Heid, Jakob and Kaupmann, Klemens and Mickel, Stuart J. and Strub, Dietrich. (2003) Ligands for expression cloning and isolation of GABA(B) receptors. Il farmaco, Vol. 58, no. 3. pp. 173-183.

Vacher, Claire-Marie and Bettler, Bernhard. (2003) GABA(B) receptors as potential therapeutic targets. Current drug targets. CNS and neurological disorders, Vol. 2, no. 4. pp. 248-259.

2002

Duthey, Béatrice and Caudron, Sara and Perroy, Julie and Bettler, Bernhard and Fagni, Laurent and Pin, Jean-Philippe and Prézeau, Laurent. (2002) A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor. Journal of biological chemistry, Vol. 277, H. 5. pp. 3236-3241.

Havlickova, Michaela and Prezeau, Laurent and Duthey, Beatrice and Bettler, Bernhard and Pin, Jean-Philippe and Blahos, Jaroslav. (2002) The intracellular loops of the GB2 subunit are crucial for G-protein coupling of the heteromeric gamma-aminobutyrate B receptor. Molecular pharmacology, Vol. 62, H. 2. pp. 343-350.

Jensen, Anders A. and Mosbacher, Johannes and Elg, Susanne and Lingenhoehl, Kurt and Lohmann, Tania and Johansen, Tommy N. and Abrahamsen, Bjarke and Mattsson, Jan P. and Lehmann, Anders and Bettler, Bernhard and Bräuner-Osborne, Hans. (2002) The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors. Molecular pharmacology, Vol. 61, H. 6. pp. 1377-1384.

Kulik, Akos and Nakadate, Kazuhiko and Nyíri, Gábor and Notomi, Takuya and Malitschek, Barbara and Bettler, Bernhard and Shigemoto, Ryuichi. (2002) Distinct localization of GABA(B) receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. The European journal of neuroscience, Vol. 15, H. 2. pp. 291-307.

Bowery, N. G. and Bettler, B. and Froestl, W. and Gallagher, J. P. and Marshall, F. and Raiteri, M. and Bonner, T. I. and Enna, S. J.. (2002) International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acid(B) receptors: structure and function. Pharmacological reviews, Vol. 54, no. 2. pp. 247-264.

2001

Gonchar, Y. and Pang, L. and Malitschek, B. and Bettler, B. and Burkhalter, A.. (2001) Subcellular localization of GABA(B) receptor subunits in rat visual cortex. The Journal of comparative neurology, Vol. 431, H. 2. pp. 182-197.

Urwyler, S. and Mosbacher, J. and Lingenhoehl, K. and Heid, J. and Hofstetter, K. and Froestl, W. and Bettler, B. and Kaupmann, K.. (2001) Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Molecular pharmacology, Vol. 60, H. 5. pp. 963-971.

Schuler, V. and Lüscher, C. and Blanchet, C. and Klix, N. and Sansig, G. and Klebs, K. and Schmutz, M. and Heid, J. and Gentry, C. and Urban, L. and Fox, A. and Spooren, W. and Jaton, A. L. and Vigouret, J. and Pozza, M. and Kelly, P. H. and Mosbacher, J. and Froestl, W. and Käslin, E. and Korn, R. and Bischoff, S. and Kaupmann, K. and van der Putten, H. and Bettler, B.. (2001) Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron, Vol. 31, H. 1. pp. 47-58.

Galvez, T. and Duthey, B. and Kniazeff, J. and Blahos, J. and Rovelli, G. and Bettler, B. and Prézeau, L. and Pin, J. P.. (2001) Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function. The EMBO journal, Vol. 20, H. 9. pp. 2152-2159.

Bianchi, M. and Rey-Roldán, E. and Bettler, B. and Ristig, D. and Malitschek, B. and Libertun, C. and Lux-Lantos, V.. (2001) Ontogenic expression of anterior pituitary GABA(B) receptor subunits. Neuropharmacology, Vol. 40, H. 2. pp. 185-192.

Pagano, A. and Rovelli, G. and Mosbacher, J. and Lohmann, T. and Duthey, B. and Stauffer, D. and Ristig, D. and Schuler, V. and Meigel, I. and Lampert, C. and Stein, T. and Prezeau, L. and Blahos, J. and Pin, J. and Froestl, W. and Kuhn, R. and Heid, J. and Kaupmann, K. and Bettler, B.. (2001) C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. Journal of neuroscience, Vol. 21, H. 4. pp. 1189-1202.

Froestl, W. and Bettler, B. and Bittiger, H. and Heid, J. and Kaupmann, K. and Mickel, S. J. and Strub, D.. (2001) Ligands for expression cloning and isolation of GABA(B) receptors. Il farmaco, Vol. 56, no. 1-2. pp. 101-105.

2000

Lorente, P. and Lacampagne, A. and Pouzeratte, Y. and Richards, S. and Malitschek, B. and Kuhn, R. and Bettler, B. and Vassort, G.. (2000) gamma-aminobutyric acid type B receptors are expressed and functional in mammalian cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 15. pp. 8664-8669.

Galvez, T. and Prezeau, L. and Milioti, G. and Franek, M. and Joly, C. and Froestl, W. and Bettler, B. and Bertrand, H. O. and Blahos, J. and Pin, J. P.. (2000) Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors. Journal of biological chemistry, Vol. 275, H. 52. pp. 41166-41174.

Galvez, T. and Urwyler, S. and Prézeau, L. and Mosbacher, J. and Joly, C. and Malitschek, B. and Heid, J. and Brabet, I. and Froestl, W. and Bettler, B. and Kaupmann, K. and Pin, J. P.. (2000) Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors : involvement of serine 269 of the GABA(B)R1 subunit. Molecular pharmacology, Vol. 57, H. 3. pp. 419-426.

Towers, S. and Princivalle, A. and Billinton, A. and Edmunds, M. and Bettler, B. and Urban, L. and Castro-Lopes, J. and Bowery, N. G.. (2000) GABAB receptor protein and mRNA distribution in rat spinal cord and dorsal root ganglia. The European journal of neuroscience, Vol. 12, H. 9. pp. 3201-3210.

Mulle, C. and Sailer, A. and Swanson, G. T. and Brana, C. and O'Gorman, S. and Bettler, B. and Heinemann, S. F.. (2000) Subunit composition of kainate receptors in hippocampal interneurons. Neuron, Vol. 28, H. 2. pp. 475-484.

1999

Marshall, F. H. and Jones, K. A. and Kaupmann, K. and Bettler, B.. (1999) GABAB receptors - the first 7TM heterodimers. Trends in Pharmacological Sciences, Vol. 20, H. 10. pp. 396-369.

Galvez, T. and Parmentier, M. L. and Joly, C. and Malitschek, B. and Kaupmann, K. and Kuhn, R. and Bittiger, H. and Froestl, W. and Bettler, B. and Pin, J. P.. (1999) Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding. Journal of biological chemistry, Vol. 274, H. 19. pp. 13362-13369.

Benke, D. and Honer, M. and Michel, C. and Bettler, B. and Mohler, H.. (1999) gamma-aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution. Journal of biological chemistry, Vol. 274, H. 38. pp. 27323-27330.

Mosbacher, J. and Kaupmann, K. and Schuler, V. and Ristig, D. and Struckmeyer, K. and Pfaff, T. and Karschin, A. and Pozza, M. F. and Bettler, B.. (1999) Processing of GABABR1 in heterologous expression systems. Annals of the New York Academy of Sciences, Vol. 868. pp. 689-692.

Bischoff, S. and Leonhard, S. and Reymann, N. and Schuler, V. and Shigemoto, R. and Kaupmann, K. and Bettler, B.. (1999) Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. The Journal of comparative neurology, Vol. 412, H. 1. pp. 1-16.

Malitschek, B. and Schweizer, C. and Keir, M. and Heid, J. and Froestl, W. and Mosbacher, J. and Kuhn, R. and Henley, J. and Joly, C. and Pin, J. P. and Kaupmann, K. and Bettler, B.. (1999) The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Molecular pharmacology, Vol. 56, H. 2. pp. 448-454.

Pfaff, T. and Malitschek, B. and Kaupmann, K. and Prézeau, L. and Pin, J. P. and Bettler, B. and Karschin, A.. (1999) Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. The European journal of neuroscience, Vol. 11, H. 8. pp. 2874-2882.

Froestl, W. and Bettler, B. and Bittiger, H. and Heid, J. and Kaupmann, K. and Mickel, S. J. and Strub, D.. (1999) Ligands for the isolation of GABA(B) receptors [corrected]. Neuropharmacology, Vol. 38, H. 11. pp. 1641-1646.

Franek, M. and Pagano, A. and Kaupmann, K. and Bettler, B. and Pin, J. P. and Blahos, J.. (1999) The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini. Neuropharmacology, Vol. 38, H. 11. pp. 1657-1666.

Lingenhoehl, K. and Brom, R. and Heid, J. and Beck, P. and Froestl, W. and Kaupmann, K. and Bettler, B. and Mosbacher, J.. (1999) Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors. Neuropharmacology, Vol. 38, H. 11. pp. 1667-1673.

Sander, T. and Peters, C. and Kämmer, G. and Samochowiec, J. and Zirra, M. and Mischke, D. and Ziegler, A. and Kaupmann, K. and Bettler, B. and Epplen, J. T. and Riess, O.. (1999) Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy. American journal of medical genetics, Vol. 88, no. 4. pp. 305-310.

Keir, M. J. and Barakat, M. J. and Dev, K. K. and Bittiger, H. and Bettler, B. and Henley, J. M.. (1999) Characterisation and partial purification of the GABA(B) receptor from the rat cerebellum using the novel antagonist [3H]CGP 62349. Molecular brain research, Vol. 71, no. 2. pp. 279-289.

1998

Bettler, B. and Kaupmann, K. and Bowery, N.. (1998) GABAB receptors: drugs meet clones. Current opinion in neurobiology, Vol. 8, H. 3. pp. 345-350.

Kaupmann, K. and Schuler, V. and Mosbacher, J. and Bischoff, S. and Bittiger, H. and Heid, J. and Froestl, W. and Leonhard, S. and Pfaff, T. and Karschin, A. and Bettler, B.. (1998) Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels. Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, No. 25. pp. 14991-14996.

Couve, A. and Filippov, A. K. and Connolly, C. N. and Bettler, B. and Brown, D. A. and Moss, S. J.. (1998) Intracellular retention of recombinant GABAB receptors. Journal of biological chemistry, Vol. 273, no. 41. pp. 26361-26367.

Zhang, C. and Bettler, B. and Duvoisin, R. M.. (1998) Differential localization of GABA(B) receptors in the mouse retina. NeuroReport, Vol. 9, H. 15. pp. 3493-3497.

Peters, H. C. and Kämmer, G. and Volz, A. and Kaupmann, K. and Ziegler, A. and Bettler, B. and Epplen, J. T. and Sander, T. and Riess, O.. (1998) Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene : evaluation of its involvement in idiopathic generalized epilepsy. Neurogenetics, Vol. 2, H. 1. pp. 47-54.

Malitschek, B. and Rüegg, D. and Heid, J. and Kaupmann, K. and Bittiger, H. and Fröstl, W. and Bettler, B. and Kuhn, R.. (1998) Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain. Molecular and cellular neuroscience, Vol. 12, H. 1-2. pp. 56-64.

Kaupmann, K. and Malitschek, B. and Schuler, V. and Heid, J. and Froestl, W. and Beck, P. and Mosbacher, J. and Bischoff, S. and Kulik, A. and Shigemoto, R. and Karschin, A. and Bettler, B.. (1998) GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature, Vol. 396, H. 6712. pp. 683-687.

Koulen, P. and Malitschek, B. and Kuhn, R. and Bettler, B. and Wässle, H. and Brandstätter, J. H.. (1998) Presynaptic and postsynaptic localization of GABA(B) receptors in neurons of the rat retina. The European journal of neuroscience, 10 (4). pp. 1446-1456.

Mulle, C. and Sailer, A. and Pérez-Otaño, I. and Dickinson-Anson, H. and Castillo, P. E. and Bureau, I. and Maron, C. and Gage, F. H. and Mann, J. R. and Bettler, B. and Heinemann, S. F.. (1998) Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature, Vol. 392, H. 6676. pp. 601-605.

1997

Bischoff, S. and Barhanin, J. and Bettler, B. and Mulle, C. and Heinemann, S.. (1997) Spatial distribution of kainate receptor subunit mRNA in the mouse basal ganglia and ventral mesencephalon. The Journal of comparative neurology, Vol. 379, H. 4. pp. 541-562.

Kaupmann, K. and Huggel, K. and Heid, J. and Flor, P. J. and Bischoff, S. and Mickel, S. J. and McMaster, G. and Angst, C. and Bittiger, H. and Froestl, W. and Bettler, B.. (1997) Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature, Vol. 386, H. 6622. pp. 239-246.

1995

Bettler, B. and Mulle, C.. (1995) Review : neurotransmitter receptors. II. AMPA and kainate receptors. Neuropharmacology, Vol. 34, H. 2. pp. 123-139.

1994

Stern-Bach, Y. and Bettler, B. and Hartley, M. and Sheppard, P. O. and O'Hara, P. J. and Heinemann, S. F.. (1994) Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron, Vol. 13, H. 6. pp. 1345-1357.

1993

Eubanks, J. H. and Puranam, R. S. and Kleckner, N. W. and Bettler, B. and Heinemann, S. F. and McNamara, J. O.. (1993) The gene encoding the glutamate receptor subunit GluR5 is located on human chromosome 21q21.1-22.1 in the vicinity of the gene for familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, No. 1. pp. 178-182.

1992

Sarfati, M. and Bettler, B. and Letellier, M. and Fournier, S. and Rubio-Trujillo, M. and Hofstetter, H. and Delespesse, G.. (1992) Native and recombinant soluble CD23 fragments with IgE suppressive activity. Immunology, Vol. 76, H. 4. pp. 662-667.

Bettler, B. and Texido, G. and Raggini, S. and Rüegg, D. and Hofstetter, H.. (1992) Immunoglobulin E-binding site in Fc epsilon receptor (Fc epsilon RII/CD23) identified by homolog-scanning mutagenesis. Journal of biological chemistry, Vol. 267, no. 1. pp. 185-191.

Bettler, B. and Egebjerg, J. and Sharma, G. and Pecht, G. and Hermans-Borgmeyer, I. and Moll, C. and Stevens, C. F. and Heinemann, S.. (1992) Cloning of a putative glutamate receptor : a low affinity kainate-binding subunit. Neuron, Vol. 8, H. 2. pp. 257-265.

Mossalayi, M. D. and Arock, M. and Delespesse, G. and Hofstetter, H. and Bettler, B. and Dalloul, A. H. and Kilchherr, E. and Quaaz, F. and Debré, P. and Sarfati, M.. (1992) Cytokine effects of CD23 are mediated by an epitope distinct from the IgE binding site. The EMBO journal, Vol. 11, H. 12. pp. 4323-4328.

Boulter, J. and Bettler, B. and Dingledine, R. and Edgebjerg, J. and Hartley, M. and Hermans-Borgmeyer, I. and Hollmann, M. and Hume, R. I. and Rogers, S. and Heinemann, S.. (1992) Molecular biology of the glutamate receptors. Clinical neuropharmacology. Supplement, 15.

1991

Delespesse, G. and Suter, U. and Mossalayi, D. and Bettler, B. and Sarfati, M. and Hofstetter, H. and Kilcherr, E. and Debre, P. and Dalloul, A.. (1991) Expression, structure, and function of the CD23 antigen. Advances in immunology, Vol. 49. pp. 149-191.

Egebjerg, J. and Bettler, B. and Hermans-Borgmeyer, I. and Heinemann, S.. (1991) Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA. Nature, Vol. 351, H. 6329. pp. 745-748.

1990

Bettler, B. and Boulter, J. and Hermans-Borgmeyer, I. and O'Shea-Greenfield, A. and Deneris, E. S. and Moll, C. and Borgmeyer, U. and Hollmann, M. and Heinemann, S.. (1990) Cloning of a novel glutamate receptor subunit, GluR5 : expression in the nervous system during development. Neuron, Vol. 5, H. 5. pp. 583-595.

1989

Bettler, B. and Hofstetter, H. and Rao, M. and Yokoyama, W. M. and Kilchherr, F. and Conrad, D. H.. (1989) Molecular structure and expression of the murine lymphocyte low-affinity receptor for IgE (Fc epsilon RII). Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 19. pp. 7566-7570.

Bettler, B. and Maier, R. and Rüegg, D. and Hofstetter, H.. (1989) Binding site for IgE of the human lymphocyte low-affinity Fc epsilon receptor (Fc epsilon RII/CD23) is confined to the domain homologous with animal lectins. Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 18. pp. 7118-7122.

1988

Bettler, B. and Ness, P. J. and Schmidlin, S. and Parish, R. W.. (1988) The upstream limit of nuclease-sensitive chromatin in Dictyostelium rRNA genes neighbors a topoisomerase I-like cluster. Journal of molecular biology, Vol. 204, H. 3. pp. 549-559.