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Items where contributor is "Amstutz, Alain"

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2023

Labhardt, N. D. and González Fernández, L. and Katende, B. and Muhairwe, J. and Bresser, M. and Amstutz, A. and Glass, T. R. and Ruhwald, M. and Sacks, J. A. and Escadafal, C. and Mareka, M. and Mooko, S. M. and de Vos, M. and Reither, K.. (2023) Head-to-head comparison of nasal and nasopharyngeal sampling using SARS-CoV-2 rapid antigen testing in Lesotho. PLoS One, 18 (3). e0278653.

Seiler, O. and Kopo, M. and Kao, M. and Lejone, T. I. and Tschumi, N. and Glass, T. G. and Brown, J. A. and Labhardt, N. D. and Amstutz, A.. (2023) HIV care preferences among young people living with HIV in Lesotho: a secondary data analysis of the PEBRA cluster randomized trial. AIDS Res Treat, 2023. p. 8124192.

2022

Firima, Emmanuel and Gonzalez, Lucia and Huber, Jacqueline and Belus, Jennifer M. and Raeber, Fabian and Gupta, Ravi and Mokhohlane, Joalane and Mphunyane, Madavida and Amstutz, Alain and Labhardt, Niklaus Daniel. (2022) Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: a scoping review protocol. F1000Research, 10. p. 535.

González Fernández, L. and Firima, E. and Robinson, E. and Ursprung, F. and Huber, J. and Amstutz, A. and Gupta, R. and Gerber, F. and Mokhohlane, J. and Lejone, T. and Ayakaka, I. and Xu, H. and Labhardt, N. D.. (2022) Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services. BMC public health, 22. p. 1126.

Gryaznov, D. and von Niederhäusern, B. and Speich, B. and Kasenda, B. and Ojeda-Ruiz, E. and Blümle, A. and Schandelmaier, S. and Mertz, D. and Odutayo, A. and Tomonaga, Y. and Amstutz, A. and Pauli-Magnus, C. and Gloy, V. and Lohner, S. and Bischoff, K. and Wollmann, K. and Rehner, L. and Meerpohl, J. J. and Nordmann, A. and Klatte, K. and Ghosh, N. and Taji Heravi, A. and Wong, J. and Chow, N. and Hong, P. and McCord-De Iaco, K. A. and Sricharoenchai, S. and Busse, J. W. and Agarwal, A. and Saccilotto, R. and Schwenkglenks, M. and Moffa, G. and Hemkens, L. and Hopewell, S. and Von Elm, E. and Briel, M.. (2022) Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE). BMJ Open, 12 (5). e053417.

Muhairwe, J. A. and Brown, J. A. and Motaboli, L. and Nsakala, B. L. and Lerotholi, M. and Amstutz, A. and Klimkait, T. and Glass, T. R. and Labhardt, N. D.. (2022) The suboptimal pediatric HIV viral load cascade: multidistrict cohort study among children taking antiretroviral therapy in Lesotho, Southern Africa. Pediatr Infect Dis J, 41 (3). e75-e80.

Scherrer, R. and Tschumi, N. and Lejone, T. I. and Kopo, M. and Motaboli, L. and Mothobi, B. and Amstutz, A. and Deml, M. J. and Lerotholi, M. and Labhardt, N. D.. (2022) eHealth supported multi-months dispensing of antiretroviral therapy: a mixed-methods preference assessment in rural Lesotho. Pilot Feasibility Stud, 8. p. 61.

Speich, B. and Gryaznov, D. and Busse, J. W. and Gloy, V. L. and Lohner, S. and Klatte, K. and Taji Heravi, A. and Ghosh, N. and Lee, H. and Mansouri, A. and Marian, I. R. and Saccilotto, R. and Nury, E. and Kasenda, B. and Ojeda-Ruiz, E. and Schandelmaier, S. and Tomonaga, Y. and Amstutz, A. and Pauli-Magnus, C. and Bischoff, K. and Wollmann, K. and Rehner, L. and Meerpohl, J. J. and Nordmann, A. and Wong, J. and Chow, N. and Hong, P. J. and Mc Cord-De Iaco, K. and Sricharoenchai, S. and Agarwal, A. and Schwenkglenks, M. and Hemkens, L. G. and von Elm, E. and Copsey, B. and Griessbach, A. N. and Schönenberger, C. and Mertz, D. and Blümle, A. and von Niederhausern, B. and Hopewell, S. and Odutayo, A. and Briel, M.. (2022) Nonregistration, discontinuation, and nonpublication of randomized trials: a repeated metaresearch analysis. PLoS Med, 19 (4). e1003980.

Brown, J. A. and Nsakala, B. L. and Mokhele, K. and Rakuoane, I. and Muhairwe, J. and Glass, T. R. and Amstutz, A. and Tschumi, N. and Belus, J. M. and Klimkait, T. and Labhardt, N. D.. (2022) Dolutegravir in real life: self-reported mental and physical health outcomes after transitioning from efavirenz- to dolutegravir-based antiretroviral therapy in a prospective cohort study in Lesotho. HIV Med. in press.

Tschumi, N. and Lerotholi, M. and Kopo, M. and Kao, M. and Lukau, B. and Nsakala, B. and Chejane, N. and Motaboli, L. and Lee, T. and Barnabas, R. and Shapiro, A. E. and van Heerden, A. and Lejone, T. I. and Amstutz, A. and Brown, J. A. and Heitner, J. and Belus, J. M. and Chammartin, F. and Labhardt, N. D.. (2022) Assessment of a viral load result-triggered automated differentiated service delivery model for people taking ART in Lesotho (the VITAL study): study protocol of a cluster-randomized trial. PLoS One, 17 (5). e0268100.

Brow, J. A. and Nsakala, B. L. and Mokhele, K. and Rakuoane, I. and Muhairwe, J. and Urda, L.. (2022) Viral suppression after transition from nonnucleoside reverse transcriptase inhibitor- to dolutegravir-based antiretroviral therapy: a prospective cohort study in Lesotho (DO-REAL study). HIV medicine, 23 (3). pp. 287-293.

Fernández, L. G. and Firima, E. and RObinson, E. and Ursprung, F. and Huber, J. and Amstutz, A. and Gupta, R. and Gerber, F. and Mokhohlane, J. and Lejone, T. and Ayakaka, I. and Xu, H. and Labhardt, N. D.. (2022) Correction: Community-based care models for arterial hypertension management in non-pregnant adults in sub-Saharan Africa: a literature scoping review and framework for designing chronic services. BMC public health, 22. p. 1640.

2021

Lohner, Szimonetta and Gryaznov, Dmitry and von Niederhäusern, Belinda and Speich, Benjamin and Kasenda, Benjamin and Ojeda-Ruiz, Elena and Schandelmaier, Stefan and Mertz, Dominik and Odutayo, Ayodele and Tomonaga, Yuki and Amstutz, Alain and Pauli-Magnus, Christiane and Gloy, Viktoria and Bischoff, Karin and Wollmann, Katharina and Rehner, Laura and Meerpohl, Joerg J. and Nordmann, Alain and Klatte, Katharina and Ghosh, Nilabh and Heravi, Ala Taji and Wong, Jacqueline and Chow, Ngai and Hong, Patrick Jiho and McCord, Kimberly and Sricharoenchai, Sirintip and Busse, Jason W. and Agarwal, Arnav and Saccilotto, Ramon and Schwenkglenks, Matthias and Moffa, Giusi and Hemkens, Lars G. and Hopewell, Sally and von Elm, Erik and Blümle, Anette and Briel, Matthias. (2021) Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study. Journal of Clinical Epidemiology, 139. pp. 340-349.

Amstutz, A. and Matsela, L. and Lejone, T. I. and Kopo, M. and Glass, T. R. and Labhardt, N. D.. (2021) Reaching absent and refusing individuals during home-based HIV testing through self-testing-at what cost? Front Med, 8. p. 653677.

Amstutz, A. and Lejone, T. I. and Khesa, L. and Kopo, M. and Kao, M. and Muhairwe, J. and Bresser, M. and Räber, F. and Klimkait, T. and Battegay, M. and Glass, T. R. and Labhardt, N. D.. (2021) Offering ART refill through community health workers versus clinic-based follow-up after home-based same-day ART initiation in rural Lesotho: the VIBRA cluster-randomized clinical trial. PLoS medicine, 18 (10). e1003839.

Brown, J. A. and Amstutz, A. and Nsakala, B. L. and Seeburg, U. and Vanobberghen, F. and Muhairwe, J. and Klimkait, T. and Daniel Labhardt, N.. (2021) Extensive drug resistance during low-level HIV viraemia while taking NNRTI-based ART supports lowering the viral load threshold for regimen switch in resource-limited settings: a pre-planned analysis from the SESOTHO trial. The journal of antimicrobial chemotherapy, 76 (5). pp. 1294-1298.

Mapesi, H. and Gupta, R. and Wilson, H. I. and Lukau, B. and Amstutz, A. and Lyimo, A. and Muhairwe, J. and Senkoro, E. and Byakuzana, T. and Mphunyane, M. and Bresser, M. and Glass, T. R. and Lambiris, M. and Fink, G. and Gingo, W. and Battegay, M. and Paris, D. H. and Rohacek, M. and Vanobberghen, F. and Labhardt, N. D. and Burkard, T. and Weisser, M.. (2021) The coArtHA trial-identifying the most effective treatment strategies to control arterial hypertension in sub-Saharan Africa: study protocol for a randomized controlled trial. Trials, 22. p. 77.

2020

Lejone, Thabo Ishmael and Kopo, Mathebe and Bachmann, Nadine and Brown, Jennifer Anne and Glass, Tracy Renée and Muhairwe, Josephine and Matsela, Tebatso and Scherrer, Ramona and Chere, Lebohang and Namane, Tilo and Labhardt, Niklaus Daniel and Amstutz, Alain. (2020) PEBRA trial - effect of a peer-educator coordinated preference-based ART service delivery model on viral suppression among adolescents and young adults living with HIV: protocol of a cluster-randomized clinical trial in rural Lesotho. BMC public health, 20. p. 425.

Amstutz, Alain and Kopo, Mathebe and Lejone, Thabo I. and Khesa, Lefu and Kao, Mpho and Muhairwe, Josephine and Glass, Tracy R. and Labhardt, Niklaus D.. (2020) "If it is left, it becomes easy for me to get tested": use of oral self-tests and community health workers to maximize the potential of home-based HIV testing among adolescents in Lesoth. Journal of the International AIDS Society, 23 (Suppl 5). e25563.

Amstutz, Alain and Nsakala, Bienvenu Lengo and Vanobberghen, Fiona and Muhairwe, Josephine and Glass, Tracy Renée and Namane, Tilo and Mpholo, Tlali and Battegay, Manuel and Klimkait, Thomas and Labhardt, Niklaus Daniel. (2020) Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho. PLoS medicine, 17 (9). e1003325.

Amstutz, Alain and Lejone, Thabo Ishmael and Khesa, Lefu and Muhairwe, Josephine and Bresser, Moniek and Vanobberghen, Fiona and Kopo, Mathebe and Kao, Mpho and Nsakala, Bienvenu Lengo and Tlali, Katleho and Klimkait, Thomas and Battegay, Manuel and Labhardt, Niklaus Daniel and Glass, Tracy Renée. (2020) Home-based oral self-testing for absent and declining individuals during a door-to-door HIV testing campaign in rural Lesotho (HOSENG): a cluster-randomised trial. The lancet. HIV, 7 (11). e752-e761.

Brown, Jennifer Anne and Ringera, Isaac and Luoga, Ezekiel and Cheleboi, Molisana and Kimera, Namvua and Muhairwe, Josephine and Kayembe, Buntshi Paulin and Molapo Hlasoa, Mosa and Kabundi, Lorraine and Yav, Ching Wey David and Mothobi, Buoang and Thahane, Lineo and Amstutz, Alain and Bachmann, Nadine and Mollel, Getrud Joseph and Bresser, Moniek and Glass, Tracy Renée and Paris, Daniel Henry and Klimkait, Thomas and Weisser, Maja and Labhardt, Niklaus Daniel. (2020) Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania. BMC infectious diseases, 20. p. 773.

Gryaznov, D. and Odutayo, A. and von Niederhausern, B. and Speich, B. and Kasenda, B. and Ojeda-Ruiz, E. and Blumle, A. and Schandelmaier, S. and Mertz, D. and Tomonaga, Y. and Amstutz, A. and Pauli-Magnus, C. and Gloy, V. and Bischoff, K. and Wollmann, K. and Rehner, L. and Lohner, S. and Meerpohl, J. J. and Nordmann, A. and Klatte, K. and Ghosh, N. and Heravi, A. T. and Wong, J. and Chow, N. and Hong, P. J. and Cord, K. M. and Sricharoenchai, S. and Busse, J. W. and Agarwal, A. and Saccilotto, R. and Schwenkglenks, M. and Moffa, G. and Hemkens, L. G. and Hopewell, S. and von Elm, E. and Briel, M.. (2020) Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects. Trials, 21. p. 896.

Amstutz, A. and Nsakala, B. L. and Cheleboi, M. and Lejone, T. I. and Hobbins, M. A. and Battegay, M.. (2020) Low rates of active hepatitis B and C infections among adults and children living with HIV and taking antiretroviral therapy: a multicenter screening study in Lesotho. Journal of medical virology, 92. pp. 3857-3861.

2019

Speich, Benjamin and Schur, Nadine and Gryaznov, Dmitry and von Niederhäusern, Belinda and Hemkens, Lars G. and Schandelmaier, Stefan and Amstutz, Alain and Kasenda, Benjamin and Pauli-Magnus, Christiane and Ojeda-Ruiz, Elena and Tomonaga, Yuki and McCord, Kimberly and Nordmann, Alain and von Elm, Erik and Briel, Matthias and Schwenkglenks, Matthias and a collaboration of the Marta Aspire Study Groups, . (2019) Resource use, costs, and approval times for planning and preparing a randomized clinical trial before and after the implementation of the new Swiss human research legislation. PLoS ONE, 14 (1). e0210669.

Amstutz, Alain and Lejone, Thabo Ishmael and Khesa, Lefu and Muhairwe, Josephine and Nsakala, Bienvenu Lengo and Tlali, Katleho and Bresser, Moniek and Vanobberghen, Fiona and Kopo, Mathebe and Kao, Mpho and Klimkait, Thomas and Battegay, Manuel and Labhardt, Niklaus Daniel and Glass, Tracy Renée. (2019) The HOSENG trial - effect of the provision of oral self-testing for absent and refusing individuals during a door-to-door HIV-testing campaign on testing coverage : protocol of a cluster-randomized clinical trial in rural Lesotho. Trials, 20. p. 496.

Amstutz, Alain and Lejone, Thabo Ishmael and Khesa, Lefu and Muhairwe, Josephine and Nsakala, Bienvenu Lengo and Tlali, Katleho and Bresser, Moniek and Tediosi, Fabrizio and Kopo, Mathebe and Kao, Mpho and Klimkait, Thomas and Battegay, Manuel and Glass, Tracy Renée and Labhardt, Niklaus Daniel. (2019) VIBRA trial - Effect of village-based refill of ART following home-based same-day ART initiation vs clinic-based ART refill on viral suppression among individuals living with HIV : protocol of a cluster-randomized clinical trial in rural Lesotho. Trials, 20. p. 522.

Glass, Tracy Renee and Motaboli, Lipontso and Nsakala, Bienvenu and Lerotholi, Malebanye and Vanobberghen, Fiona and Amstutz, Alain and Lejone, Thabo Ishmael and Muhairwe, Josephine and Klimkait, Thomas and Labhardt, Niklaus Daniel. (2019) The viral load monitoring cascade in a resource-limited setting : a prospective multicentre cohort study after introduction of routine viral load monitoring in rural Lesotho. PLoS ONE, 14 (8). e0220337.

Labhardt, Niklaus Daniel and Ringera, Isaac and Lejone, Thabo Ishmael and Amstutz, Alain and Klimkait, Thomas and Muhairwe, Josephine and Glass, Tracy Renee. (2019) Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa. BMC public health, 19. p. 1441.

Amstutz, Alain and Brown, Jennifer Anne and Ringera, Isaac and Muhairwe, Josephine and Lejone, Thabo Ishmael and Klimkait, Thomas and Glass, Tracy Renée and Labhardt, Niklaus Daniel. (2019) Engagement in care, viral suppression, drug resistance and reasons for non-engagement after home-based same-day ART initiation in Lesotho: a two-year follow-up of the CASCADE trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71 (10). pp. 2608-2614.

2018

Amstutz, Alain and Nsakala, Bienvenu Lengo and Vanobberghen, Fiona and Muhairwe, Josephine and Glass, Tracy Renée and Achieng, Beatrice and Sepeka, Mamorena and Tlali, Katleho and Sao, Lebohang and Thin, Kyaw and Klimkait, Thomas and Battegay, Manuel and Labhardt, Niklaus Daniel. (2018) SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa. BMC infectious diseases, 18 (1). p. 76.

Labhardt, N. D. and Ringera, I. and Lejone, T. I. and Klimkait, T. and Muhairwe, J. and Amstutz, A. and Glass, T. R.. (2018) Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho : the CASCADE randomized clinical trial. JAMA : the journal of the American Medical Association, 319 (11). pp. 1103-1112.

2017

Schandelmaier, Stefan and Tomonaga, Yuki and Bassler, Dirk and Meerpohl, Joerg J. and von Elm, Erik and You, John J. and Bluemle, Anette and Lamontagne, Francois and Saccilotto, Ramon and Amstutz, Alain and Bengough, Theresa and Stegert, Mihaela and Olu, Kelechi K. and Tikkinen, Kari A. O. and Neumann, Ignacio and Carrasco-Labra, Alonso and Faulhaber, Markus and Mulla, Sohail M. and Mertz, Dominik and Akl, Elie A. and Sun, Xin and Busse, Jason W. and Ferreira-González, Ignacio and Nordmann, Alain and Gloy, Viktoria and Raatz, Heike and Moja, Lorenzo and Rosenthal, Rachel and Ebrahim, Shanil and Vandvik, Per O. and Johnston, Bradley C. and Walter, Martin A. and Burnand, Bernard and Schwenkglenks, Matthias and Hemkens, Lars G. and Guyatt, Gordon and Bucher, Heiner C. and Kasenda, Benjamin and Briel, Matthias. (2017) Premature Discontinuation of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study. The Journal of Pediatrics, 184. pp. 209-214.e1.