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Translesion DNA synthesis : little fingers teach tolerance

Fleck, Oliver and Schär, Primo. (2004) Translesion DNA synthesis : little fingers teach tolerance. Current biology, Vol. 14, H. 10 , R389-391.

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Official URL: http://edoc.unibas.ch/dok/A5254004

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Abstract

DNA synthesis on a damaged template requires tolerant DNA polymerases. Crystallographic analysis has captured a Y-family polymerase synthesizing across an abasic site, providing insight into the mechanisms of DNA damage tolerance and mutation.
Faculties and Departments:03 Faculty of Medicine > Departement Biomedizin > Division of Biochemistry and Genetics > Molecular Genetics (Schär)
UniBasel Contributors:Schär, Primo Leo
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Cell Press
ISSN:0960-9822
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:22 Mar 2012 14:23
Deposited On:22 Mar 2012 13:33

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