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Sustaining the control of Schistosoma mansoni in western Côte d'Ivoire : baseline findings before the implementation of a randomized trial

Assaré, Rufin K. and Hürlimann, Eveline and Ouattara, Mamadou and N'Guessan, Nicaise A. and Tian-Bi, Yves-Nathan T. and Yapi, Ahoua and Yao, Patrick K. and Coulibaly, Jean T. and Knopp, Stefanie and N'Goran, Eliézer K. and Utzinger, Jürg. (2016) Sustaining the control of Schistosoma mansoni in western Côte d'Ivoire : baseline findings before the implementation of a randomized trial. American journal of tropical medicine and hygiene, 94 (2). pp. 352-360.

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Official URL: http://edoc.unibas.ch/42129/

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Abstract

We report baseline findings before the implementation of a 4-year intervention trial designed to assess the impact of three different school-based treatment schedules with praziquantel to sustain the control of intestinal schistosomiasis. The baseline survey was conducted in 75 schools of western Côte d'Ivoire previously identified with moderate Schistosoma mansoni endemicity (prevalence: 10-24% in children aged 13-14 years). Three stool samples collected over consecutive days were subjected to duplicate Kato-Katz thick smears each. A questionnaire was administered to collect village-specific information that is relevant for schistosomiasis transmission. Overall, 4,953 first graders (aged 5-8 years) and 7,011 school children (aged 9-12 years) had complete parasitologic data. The overall prevalence of S. mansoni was 5.4% among first graders and 22.1% in 9- to 12-year-old children. Open defecation was practiced in all villages. The current baseline findings will be important to better understand the dynamics of S. mansoni prevalence and intensity over the course of this trial that might be governed by village characteristics and specific treatment interventions.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Eco System Health Sciences > Health Impact Assessment (Utzinger)
UniBasel Contributors:Utzinger, Jürg and Knopp, Stefanie
Item Type:Article, refereed
Publisher:Williams and Wilkins
ISSN:0002-9637
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:30 Jun 2016 11:03
Deposited On:28 Apr 2016 07:40

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