Luu, V. D. and Fischer, B. and von Teichman, A. and Boysen, G. and Mertz, K. and Zimmermann, P. and Moch, H. and Schraml, P.. (2008) [Von-Hippel-Lindau gene mutation types. Association of gene expression signatures in clear cell renal cell carcinoma]. Der Pathologe, Vol. 29, Suppl. 2. pp. 303-307.
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Official URL: http://edoc.unibas.ch/dok/A6005295
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Abstract
The von-Hippel-Lindau (VHL) tumor suppressor is a multifunctional protein. VHL mutations are common in sporadic clear cell renal cell carcinoma (ccRCC). Different mutation types may specifically alter pVHL functions, which have significant impact on gene expression and, consequently, on the disease outcome. The aim of this study was to identify gene expression signatures that correlate with specific VHL gene mutation types in RCC.
| Faculties and Departments: | 03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB 03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB |
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| UniBasel Contributors: | Schraml, Peter Hans |
| Item Type: | Article, refereed |
| Article Subtype: | Research Article |
| Publisher: | Springer |
| ISSN: | 0172-8113 |
| Note: | Publication type according to Uni Basel Research Database: Journal article |
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| Identification Number: |
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| Last Modified: | 23 May 2014 08:33 |
| Deposited On: | 23 May 2014 08:33 |
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