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Novel DOTA-based prochelator for divalent peptide vectorization : synthesis of dimeric bombesin analogues for multimodality tumor imaging and therapy

Abiraj, K. and Jaccard, H. and Kretzschmar, M. and Helm, L. and Maecke, H. R.. (2008) Novel DOTA-based prochelator for divalent peptide vectorization : synthesis of dimeric bombesin analogues for multimodality tumor imaging and therapy. Chemical Communications, 44 (28). pp. 3248-3250.

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Official URL: http://edoc.unibas.ch/dok/A6004858

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Abstract

Dimeric peptidic vectors, obtained by the divalent grafting of bombesin analogues on a newly synthesized DOTA-based prochelator, showed improved qualities as tumor targeted imaging probes in comparison to their monomeric analogues.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Ehemalige Einheiten Querschnittsfächer (Klinik) > Radiologische Chemie (Mindt)
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Ehemalige Einheiten Querschnittsfächer (Klinik) > Radiologische Chemie (Mindt)
UniBasel Contributors:Mäcke, Helmut
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Royal Society of Chemistry
ISSN:0022-4936
Note:Publication type according to Uni Basel Research Database: Journal article
Identification Number:
Last Modified:01 Dec 2016 07:19
Deposited On:25 Apr 2014 08:01

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