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Effect of supervised training on FEV1 in cystic fibrosis : a randomised controlled trial

Kriemler, Susi and Kieser, Stephanie and Junge, Sibylle and Ballmann, Manfred and Hebestreit, Alexandra and Schindler, Christian and Stüssi, Christoph and Hebestreit, Helge. (2013) Effect of supervised training on FEV1 in cystic fibrosis : a randomised controlled trial. Journal of cystic fibrosis, Vol. 12, H. 6. pp. 714-720.

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Official URL: http://edoc.unibas.ch/dok/A6205638

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Abstract

Long-term exercise interventions have been shown to improve vital capacity in cystic fibrosis (CF). Yet, no data are available indicating positive effects of long-term exercise training on FEV1.; 39 Swiss patients with CF were randomly divided into strength training (ST, n=12), endurance training (AT, n=17) and controls (CONCH, n=10), and also compared with age-matched Swiss (n=35) and German (n=701) CF registry data. A partially supervised training of 3×30min/week for 6months took place with measurements at baseline and after 3, 6, 12 and 24months. Primary outcome was FEV1 at 6months.; FEV1 increased significantly in both training groups compared with CONCH (AT:+5.8±0.95, ST:+7.4±2.5, CONCH:-11.5±2.7% predicted, p>0.001) and both registry groups at 6months. At 24months, changes in favour of the training groups persisted marginally compared with CONCH, but not compared with registry data.; A partially supervised training over 6months improved FEV1 but effects were basically gone 18months off training. Regular long-term training should be promoted as essential part of treatment in CF.
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Former Units within Swiss TPH > Physical Activity and Health (Kriemler)
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH)
UniBasel Contributors:Kriemler, Susi and Schindler, Christian
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:Elsevier
ISSN:1569-1993
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:31 Jan 2014 09:49
Deposited On:31 Jan 2014 09:49

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