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Fluorescence in situ hybridization in the definitive diagnosis of malignant mesothelioma in effusion cytology

Savic, Spasenija and Franco, Noreli and Grilli, Bruno and Barascud, Audrey de Vito and Herzog, Michelle and Bode, Beata and Loosli, Heinz and Spieler, Peter and Schönegg, René and Zlobec, Inti and Clark, Douglas P. and Herman, James G. and Bubendorf, Lukas. (2010) Fluorescence in situ hybridization in the definitive diagnosis of malignant mesothelioma in effusion cytology. Chest, Vol. 138, H. 1. pp. 137-144.

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Official URL: http://edoc.unibas.ch/dok/A6003648

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Abstract

Distinction of malignant mesothelioma (MM) from reactive mesothelial cells (RM) in effusions is notoriously difficult. The aim of our study was to test chromosomal aberrations detected by fluorescence in situ hybridization (FISH) in the diagnosis of MM in effusion cytology and to explore the potential role of p16, p14, and p15 gene methylation as an alternative mechanism of tumor suppressor gene inactivation.
Faculties and Departments:03 Faculty of Medicine > Bereich Querschnittsfächer (Klinik) > Pathologie USB
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Querschnittsfächer (Klinik) > Pathologie USB
UniBasel Contributors:Zlobec, Inti
Item Type:Article, refereed
Article Subtype:Research Article
Publisher:American College of Chest Physicians
ISSN:0012-3692
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:19 Jul 2013 07:43
Deposited On:19 Jul 2013 07:35

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