edoc

Prevalence of airflow obstruction in smokers and never smokers in Switzerland

Bridevaux, P.-O. and Probst-Hensch, N. M. and Schindler, C. and Curjuric, I. and Felber Dietrich, D. and Braendli, O. and Brutsche, M. and Burdet, L. and Frey, M. and Gerbase, M. W. and Ackermann-Liebrich, U. and Pons, M. and Tschopp, J.-M. and Rochat, T. and Russi, E. W.. (2010) Prevalence of airflow obstruction in smokers and never smokers in Switzerland. The European respiratory journal, Vol. 36, H. 6. S. 1259-1269.

Full text not available from this repository.

Official URL: http://edoc.unibas.ch/dok/A5842994

Downloads: Statistics Overview

Abstract

We aimed to measure age-specific prevalence of airflow obstruction (AO) in Switzerland in smokers and never smokers using pulmonary function tests and respiratory symptoms from 6126 subjects participating in the Swiss Cohort Study on Air Pollution and Lung Diseases in Adults.The lower limit of normal of FEV1/FVC ratio was used to define AO. Severity of AO was graded according to the recommendations of the Global Initiative for Chronic Obstructive Lung Disease.Prevalence of AO ranged from 2.5% in subjects aged 30-39 to 8.0% in those aged 70 or more. In multivariate analysis, age (ORaged70+ vs aged 30-39 2.8), smoking (OR 1.8) and asthma, (OR 6.7) were associated with AO. Never smokers constituted 29.3 % of subjects with AO. Never smokers with AO were younger, male and reported more frequently asthma than obstructive smokers. Obstructive smokers and never smokers had similar level of symptoms and quality of life impairment.Prevalence of AO in Switzerland is similar in magnitude compared to other developed countries. Never smokers account for a third of the prevalence which is higher than elsewhere. AO in never smokers deserve attention because of its frequency and its similar health impact than in smokers
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Biostatistics > Biostatistics - Frequency Modelling (Schindler)
03 Faculty of Medicine > Bereich Medizinische Fächer (Klinik) > Pneumologie
03 Faculty of Medicine > Departement Klinische Forschung > Bereich Medizinische Fächer (Klinik) > Pneumologie
09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Epidemiology and Public Health (EPH) > Chronic Disease Epidemiology > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin > Genetic Epidemiology of Non-Communicable Diseases (Probst-Hensch)
03 Faculty of Medicine > Departement Public Health > Sozial- und Präventivmedizin
UniBasel Contributors:Brutsche, Martin and Schindler, Christian and Felber Dietrich, Denise and Curjuric, Ivan and Ackermann-Liebrich, Ursula A. and Probst Hensch, Nicole
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Munksgaard
ISSN:0903-1936
Note:Publication type according to Uni Basel Research Database: Journal article
Related URLs:
Identification Number:
Last Modified:07 Dec 2012 13:03
Deposited On:07 Dec 2012 12:59

Repository Staff Only: item control page