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The homeotic gene Sex Combs Reduced of Drosophila: gene structure and embryonic expression

LeMotte, P. K. and Kuroiwa, A. and Fessler, L. I. and Gehring, W. J.. (1989) The homeotic gene Sex Combs Reduced of Drosophila: gene structure and embryonic expression. The EMBO journal, Vol. 8, H. 1. S. 219-227.

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Official URL: http://edoc.unibas.ch/dok/A5257336

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Abstract

The homeotic gene Sex Combs Reduced (Scr) of Drosophila is required during embryogenesis for labial and first thoracic segment development. We define the Scr gene structure, showing that the major embryonic transcript is proximal to the fushi tarazu gene, and report the sequence of the transcript, which encodes a 413-amino acid, homeodomain-containing protein. We describe Scr protein distribution throughout embryogenesis. Expression begins at gastrulation and is eventually apparent in three tissues, epidermis, nervous system and visceral mesoderm, though there are clear contrasts in the domains of expression in these three tissues.
Faculties and Departments:05 Faculty of Science > Departement Biozentrum > Former Organization Units Biozentrum > Cell Biology (Gehring)
UniBasel Contributors:Gehring, Walter Jakob
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Nature Publishing Group
ISSN:0261-4189
Note:Publication type according to Uni Basel Research Database: Journal article
Last Modified:22 Mar 2012 14:19
Deposited On:22 Mar 2012 13:17

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