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Phase change material for thermotherapy of Buruli ulcer : modelling as an aid to implementation

Braxmeier, S. and Hellmann, M. and Beck, A. and Umboock, A. and Pluschke, G. and Junghanss, T. and Weinlaeder, H.. (2009) Phase change material for thermotherapy of Buruli ulcer : modelling as an aid to implementation. Journal of medical engineering & technology : an international bi-monthly journal promoting the application of engineering and technology in medical research and clinical medicine, Vol. 33, H. 7. S. 559-566.

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Official URL: http://edoc.unibas.ch/dok/A5843293

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Abstract

A mathematical model was developed and validated to predict the thermal behaviour of a heat application device based on a phase change material (pcm) for the heat treatment of Mycobacterium ulcerans infection (Buruli ulcer). The thermal model allows the prediction of skin surface temperatures and an optimization of the amount of pcm with respect to discharge time. A first prototype of such a pcm bandage was manufactured and used in a proof-of-principal trial in Cameroon. The experimental data were analysed and yielded no difference in thermoregulatory response between people living in hot or moderate climate. Short-term maximum skin surface temperatures of 42 degrees C are tolerable; the pcm bandage keeps the skin surface temperature above 40 degrees C for about four to five hours. This makes such pcm bandages an ideal device for the heat treatment of Buruli ulcer. The pcm bandage is easy to apply, cheap, and thus is well suited for use in low-resource countries
Faculties and Departments:09 Associated Institutions > Swiss Tropical and Public Health Institute (Swiss TPH) > Department of Medical Parasitology and Infection Biology > Molecular Immunology (Pluschke)
UniBasel Contributors:Pluschke, Gerd
Item Type:Article, refereed
Bibsysno:Link to catalogue
Publisher:Taylor & Francis
ISSN:1464-522x
Note:Publication type according to Uni Basel Research Database: Journal article
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Last Modified:14 Sep 2012 07:18
Deposited On:14 Sep 2012 06:43

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