Knobloch, Bernd and Okruszek, Andrzej and Sigel, Helmut. (2008) Inosylyl(3'-< 5')inosine (Ipl⁻): Acid-base and metal ion-binding properties of a dinucleoside monophosphate in aqueous solution. Inorganic chemistry, Vol. 47, H. 7. S. 2641-2648.
Full text not available from this repository.
Official URL: http://edoc.unibas.ch/dok/A5248835
The acidity constants of the (N7)H+ sites of inosylyl(3`-< 5`)inosine (Ipl(-)) were estimated and those of its (N1)H sites were measured by potentiometric pH titrations in aqueous solution (25 degrees C; l = 0.1 M, NaNO3). The same method was used for the determination of the stability constants of the 1:1 complexes formed between Mg2+, CO2+, Ni2+, Zn2+, or Cd2+ (= M2+) and (Ipl - H)(2-) and, in the case of Mg2+, also of (Ipl - 2H)(3-). The stability constants of the M(Ipl)(+) complexes were estimated. The acidity constants of H(inosine)+ and the stability constants of the M(Ino)(2+) and M(Ino - H)(+) complexes were taken from the literature. The comparison of these and related data allows the conclusion that, in the M(Ipl - H) species, chelates are formed; most likely they are preferably of an N7/N7 type. or the metal ions CO2+, Ni2+, Zn2+, or Cd2+, the formation degrees of the chelates are on the order of 60-80 Mg(Ipl - H) complexes. It is noteworthy that the (N1)H deprotonation, which leads to the M(Ipl - H) species, occurs in all M(Ipl)(+) complexes in the physiological pH range of about 7.5 or even below.
|Faculties and Departments:||05 Faculty of Science > Departement Chemie > Chemie|
|Item Type:||Article, refereed|
|Bibsysno:||Link to catalogue|
|Publisher:||American Chemical Society|
|Note:||Publication type according to Uni Basel Research Database: Journal article|
|Last Modified:||14 Sep 2012 08:56|
|Deposited On:||22 Mar 2012 15:16|
Repository Staff Only: item control page